The selective contribution of the right cerebellar lobule VI to reading

2021 ◽  
Author(s):  
Hehui Li ◽  
Rebecca A. Marks ◽  
Lanfang Liu ◽  
Jia Zhang ◽  
Hejing Zhong ◽  
...  
Keyword(s):  
Phonological Processing ◽  
Posterior Part ◽  
Chinese Characters ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Viewing Condition ◽  
Activation Patterns ◽  
English Bilingual ◽  
Passive Viewing ◽  
The Right

Extensive studies have reported significant cerebellar activation during reading tasks. However, it is still unclear which regions in the cerebellum are specifically involved in reading and what this involvement entails. With functional magnetic resonance imaging, we compared Chinese-English bilingual children’s cerebellar neural activity between reading and non-reading conditions and between Chinese characters and English words in a passive viewing paradigm. We observed that the posterior part of the right lobule VI showed greater activation in the reading compared to non-reading tasks. Reading specificity index was significantly in this region. Functional decoding via Neurosynth further showed that this region was responsible for phonological processing and connected with the cerebral reading areas. These results suggest that the posterior part of the right lobule VI might be a reading-selective region in the cerebellum. However, we did not observe any significantly separable activation patterns in the cerebellum between Chinese characters and English words, indicating that the region preferentially responding to reading may not be able to differentiate scripts in a passive viewing condition. In general, these findings deepen our understanding of how the cerebellum contributes to reading.

scholarly journals Effects of behavioural activation on the neural circuit related to intrinsic motivation

BJPsych Open ◽  
2018 ◽  
Vol 4 (5) ◽  
pp. 317-323 ◽  
Author(s):  
Asako Mori ◽  
Yasumasa Okamoto ◽  
Go Okada ◽  
Koki Takagaki ◽  
Masahiro Takamura ◽  
...  
Keyword(s):  
Intrinsic Motivation ◽  
Neural Circuit ◽  
Intervention Group ◽  
Behavioural Activation ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Neural Basis ◽  
Efficient Treatment ◽  
The Right ◽  
Magnetic Resonance Imaging Scanning

BackgroundBehavioural activation is an efficient treatment for depression and can improve intrinsic motivation. Previous studies have revealed that the frontostriatal circuit is involved in intrinsic motivation; however, there are no data on how behavioural activation affects the frontostriatal circuit.AimsWe aimed to investigate behavioural activation-related changes in the frontostriatal circuit.MethodFifty-nine individuals with subthreshold depression were randomly assigned to either the intervention or non-intervention group. The intervention group received five weekly behavioural activation sessions. The participants underwent functional magnetic resonance imaging scanning on two separate occasions while performing a stopwatch task based on intrinsic motivation. We investigated changes in neural activity and functional connectivity after behavioural activation.ResultsAfter behavioural activation, the intervention group had increased activation and connectivity in the frontostriatal region compared with the non-intervention group. The increased activation in the right middle frontal gyrus was correlated with an improvement of subjective sensitivity to environmental rewards.ConclusionsBehavioural activation-related changes to the frontostriatal circuit advance our understanding of psychotherapy-induced improvements in the neural basis of intrinsic motivation.Declaration of interestNone.

Coerced training of the nondominant hand resulting in cortical reorganization: a high-field functional magnetic resonance imaging study

2004 ◽  
Vol 101 (2) ◽  
pp. 310-313 ◽  
Author(s):  
Tsutomu Nakada ◽  
Yukihiko Fujii ◽  
Ingrid L. Kwee
Keyword(s):  
Magnetic Resonance Imaging ◽  
High Field ◽  
Cortical Reorganization ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Content Type ◽  
Hand Motion ◽  
Left Handed ◽  
The Right ◽  
Fine Print

Object. The authors investigated brain strategies associated with hand use in an attempt to clarify genetic and nongenetic factors influencing handedness by using high-field functional magnetic resonance imaging. Methods. Three groups of patients were studied. The first two groups comprised individuals in whom handedness developed spontaneously (right-handed and left-handed groups). The third group comprised individuals who were coercively trained to use the right hand and developed mixed handedness, referred to here as trained ambidexterity. All trained ambidextrous volunteers were certain that they were innately left-handed, but due to social pressure had modified their preferred hand use for certain tasks common to the right hand. Although right-handed and left-handed volunteers displayed virtually identical cortical activation, involving homologous cortex primarily located contralateral to the hand motion, trained ambidextrous volunteers exhibited a clearly unique activation pattern. During right-handed motion, motor areas in both hemispheres were activated in these volunteers. During left-handed motion, the right supplemental motor area and the right intermediate zone of the anterior cerebellar lobe were activated significantly more frequently than observed in naturally right-handed or left-handed volunteers. Conclusions. The results provide strong evidence that cortical organization of spontaneously developed right- and left-handedness involves homologous cortex primarily located contralateral to the hand motion, and this organization is likely to be prenatally determined. By contrast, coerced training of the nondominant hand during the early stages of an individual's development results in mixed handedness (trained ambidexterity), indicating cortical reorganization.

scholarly journals Aberrant Brain Functional Connectivity Strength and Effective Connectivity in Patients with Type 2 Diabetes Mellitus

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Xi Guo ◽  
Su Wang ◽  
Yu-Chen Chen ◽  
Heng-Le Wei ◽  
Gang-Ping Zhou ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Disease Duration ◽  
Effective Connectivity ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Functional Connectivity Strength ◽  
The Right ◽  
Brain Functional Connectivity ◽  
Connectivity Strength

Alterations of brain functional connectivity in patients with type 2 diabetes mellitus (T2DM) have been reported by resting-state functional magnetic resonance imaging studies, but the underlying precise neuropathological mechanism remains unclear. This study is aimed at investigating the implicit alterations of functional connections in T2DM by integrating functional connectivity strength (FCS) and Granger causality analysis (GCA) and further exploring their associations with clinical characteristics. Sixty T2DM patients and thirty-three sex-, age-, and education-matched healthy controls (HC) were recruited. Global FCS analysis of resting-state functional magnetic resonance imaging was performed to explore seed regions with significant differences between the two groups; then, GCA was applied to detect directional effective connectivity (EC) between the seeds and other brain regions. Correlations of EC with clinical variables were further explored in T2DM patients. Compared with HC, T2DM patients showed lower FCS in the bilateral fusiform gyrus, right superior frontal gyrus (SFG), and right postcentral gyrus, but higher FCS in the right supplementary motor area (SMA). Moreover, altered directional EC was found between the left fusiform gyrus and bilateral lingual gyrus and right medial frontal gyrus (MFG), as well as between the right SFG and bilateral frontal regions. In addition, triglyceride, insulin, and plasma glucose levels were correlated with the abnormal EC of the left fusiform, while disease duration and cognitive function were associated with the abnormal EC of the right SFG in T2DM patients. These results suggest that T2DM patients show aberrant brain function connectivity strength and effective connectivity which is associated with the diabetes-related metabolic characteristics, disease duration, and cognitive function, providing further insights into the complex neural basis of diabetes.

scholarly journals Resting-State Functional Magnetic Resonance Imaging and Functional Connectivity Density Mapping in Patients With Optic Neuritis

2021 ◽  
Vol 15 ◽  
Author(s):  
Ke Song ◽  
Yong Wang ◽  
Mei-Xia Ren ◽  
Jiao Li ◽  
Ting Su ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Connectivity ◽  
Functional Magnetic Resonance Imaging ◽  
Optic Neuritis ◽  
Resting State ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Functional Connectivity Density ◽  
The Right

Background: Using resting-state functional connectivity (rsFC), we investigated alternations in spontaneous brain activities reflected by functional connectivity density (FCD) in patients with optic neuritis (ON).Methods: We enrolled 28 patients with ON (18 males, 10 females) and 24 healthy controls (HCs; 16 males, 8 females). All subjects underwent functional magnetic resonance imaging (fMRI) in a quiet state to determine the values of rsFC, long-range FCD (longFCD), and short-range FCD (IFCD). Receiver operating characteristic (ROC) curves were generated to distinguish patients from HCs.Results: The ON group exhibited obviously lower longFCD values in the left inferior frontal gyrus triangle, the right precuneus and the right anterior cingulate, and paracingulate gyri/median cingulate and paracingulate gyri. The left median cingulate and paracingulate gyri and supplementary motor area (SMA) were also significantly lower. Obviously reduced IFCD values were observed in the left middle temporal gyrus/angular gyrus/SMA and right cuneus/SMA compared with HCs.Conclusion: Abnormal neural activities were found in specific brain regions in patients with ON. Specifically, they showed significant changes in rsFC, longFCD, and IFCD values. These may be useful to identify the specific mechanism of change in brain function in ON.

scholarly journals A comparative study of brain activation patterns associated with sexual arousal between males and females using 3.0-T functional magnetic resonance imaging

Sexual Health ◽  
2014 ◽  
Vol 11 (1) ◽  
pp. 11 ◽  
Author(s):  
Gwang-Won Kim ◽  
Gwang-Woo Jeong
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Gender Difference ◽  
Functional Magnetic Resonance Imaging ◽  
Sexual Arousal ◽  
Brain Activation ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Activation Patterns ◽  
3.0 T

Background In contrast to the previous studies using a 1.5-T magnetic resonance imaging system, our study was performed on a higher magnetic field strength, 3.0 T, to gain more valuable information on the functional brain anatomy associated with visual sexual arousal for discriminating the gender difference by increasing the detection power of brain activation. Methods: Twenty-four healthy subjects consisting of 12 males and 12 females underwent functional magnetic resonance imaging examination for this study. Brain activity was measured while viewing erotic videos. Results: The predominant activation areas observed in males as compared with females included the hypothalamus, the globus pallidus, the head of the caudate nucleus, the parahippocampal gyrus, the amygdala and the septal area, whereas the predominant activation in females was observed in the anterior cingulate gyrus and the putamen. Conclusion: Our findings suggest that the brain activation patterns associated with visual sexual arousal are specific to gender. This gender difference in brain activation patterns is more remarkable at higher magnet field (3.0 T) than at 1.5 T.

scholarly journals Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging

2006 ◽  
Vol 189 (6) ◽  
pp. 560-561 ◽  
Author(s):  
Therese Van Amelsvoort ◽  
Nicole Schmitz ◽  
Eileen Daly ◽  
Quinton Deeley ◽  
Hugo Critchley ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Emotional Processing ◽  
Brain Regions ◽  
Functional Neuroanatomy ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
The Right ◽  
Velo Cardio Facial Syndrome

SummaryWe studied the functional neuroanatomy of social behaviour in velo-cardio-facial syndrome (VCFS) using a facial emotional processing task and functional magnetic resonance imaging in adults with this syndrome and controls matched for age and IQ. The VCFS group had less activation in the right insula and frontal brain regions and more activation in occipital regions. Genetically determined abnormalities in pathways including those involved in emotional processing may underlie deficits in social cognition in people with VCFS.

Sign in / Sign up

Export Citation Format

Share Document