scholarly journals Infant Development as Uncertainty Reduction: Bayesian Insights on Phonological Acquisition

2020 ◽  
Author(s):  
Christopher Martin Mikkelsen Cox ◽  
Riccardo Fusaroli ◽  
Tamar Keren-Portnoy ◽  
Andreas Roepstorff

Bayesian accounts of development posit that infants form predictions about the causes of sensory signals in their environment and select actions that resolve the largest amount of uncertainty. This paper considers how this approach to infant development can inform and unify insights from experimental research on early cognitive development and language acquisition. In order to establish whether infants’ early inferential abilities conform to the basic assumptions of a Bayesian approach to cognition, we first conduct a systematic review of experimental studies on infants’ ability to form predictions about probabilistic contingencies. These studies provide evidence that infants exhibit sensitivity to the probabilistic structure of their surrounding environment and recruit their own uncertainty to guide their exploration of information in the world. We then demonstrate how these Bayesian computational principles may apply in the context of language acquisition by conducting a second systematic review of experiments on the facilitative role of infants’ vocal production. These studies indicate that infants are more likely to produce and allocate attention to those speech sounds that best afford the opportunity to reduce prediction error over time. This paper demonstrates how Bayesian models of cognition can offer a unifying framework to advance the understanding of cognitive processes in early development. This framework not only gives a larger perspective to current findings, but also provides conceptual tools to enable investigation of infants’ individual trajectories of behavioural change.

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e031598 ◽  
Author(s):  
Clare Meernik ◽  
Hannah M Baker ◽  
Sarah D Kowitt ◽  
Leah M Ranney ◽  
Adam O Goldstein

ObjectivesGiven the exponential increase in the use of e-cigarettes among younger age groups and in the growth in research on e-cigarette flavours, we conducted a systematic review examining the impact of non-menthol flavoured e-cigarettes on e-cigarette perceptions and use among youth and adults.DesignPubMed, Embase, PyscINFO and CINAHL were systematically searched for studies published and indexed through March 2018.Eligibility criteriaQuantitative observational and experimental studies that assessed the effect of non-menthol flavours in e-cigarettes on perceptions and use behaviours were included. Specific outcome measures assessed are appeal, reasons for use, risk perceptions, susceptibility, intention to try, initiation, preference, current use, quit intentions and cessation.Data extraction and synthesisThree authors independently extracted data related to the impact of flavours in tobacco products. Data from a previous review were then combined with those from the updated review for final analysis. Results were then grouped and analysed by outcome measure.ResultsThe review included 51 articles for synthesis, including 17 published up to 2016 and an additional 34 published between 2016 and 2018. Results indicate that non-menthol flavours in e-cigarettes decrease harm perceptions (five studies) and increase willingness to try and initiation of e-cigarettes (six studies). Among adults, e-cigarette flavours increase product appeal (seven studies) and are a primary reason many adults use the product (five studies). The role of flavoured e-cigarettes on smoking cessation remains unclear (six studies).ConclusionThis review provides summary data on the role of non-menthol flavours in e-cigarette perceptions and use. Consistent evidence shows that flavours attract both youth and adults to use e-cigarettes. Given the clear findings that such flavours increase product appeal, willingness to try and initiation among youth, banning non-menthol flavours in e-cigarettes may reduce youth e-cigarette use. Longitudinal research is needed to examine any role flavours may play in quit behaviours among adults.


2019 ◽  
Vol 29 (1) ◽  
pp. 3-20 ◽  
Author(s):  
Genevieve A. Le Bas ◽  
George J. Youssef ◽  
Jacqui A. Macdonald ◽  
Larissa Rossen ◽  
Samantha J. Teague ◽  
...  

2015 ◽  
Vol 38 (3) ◽  
Author(s):  
Ting Wang ◽  
Lin Jiang

AbstractThe role of written corrective feedback (CF) in the process of acquiring a second language (L2) has been an issue of considerable controversies over past decades. This study thus endeavors to extend current work on written CF by investigating and comparing the effect on collocation learning of one traditional type of feedback—direct corrective feedback (DCF)—with an innovative type of error correction, feedback provided within context—situated feedback (SF). The effects of the two types of written feedback were measured by examining the accurate use of target collocations in a translation test and a multiple choice test completed by 73 intermediate EFL students in China. Three groups were formed: a DCF group, an SF group, and a control group. The study found that both treatment groups outperformed the control group in the posttests and delayed posttests and that there were significant advantages of the SF group in comparison to the DCF group in both posttests. The results suggested that the provision of written CF was helpful for collocation learning and that situational context could promote the facilitative role of written CF in language acquisition. These findings are discussed from the perspectives of both second language acquisition (SLA) theory and language pedagogy and implications for future research efforts are put forward.


Toxins ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 788
Author(s):  
Alicja Rydzewska-Rosołowska ◽  
Natalia Sroka ◽  
Katarzyna Kakareko ◽  
Mariusz Rosołowski ◽  
Edyta Zbroch ◽  
...  

The last years have brought an abundance of data on the existence of a gut-kidney axis and the importance of microbiome in kidney injury. Data on kidney-gut crosstalk suggest the possibility that microbiota alter renal inflammation; we therefore aimed to answer questions about the role of microbiome and gut-derived toxins in acute kidney injury. PubMed and Cochrane Library were searched from inception to October 10, 2020 for relevant studies with an additional search performed on ClinicalTrials.gov. We identified 33 eligible articles and one ongoing trial (21 original studies and 12 reviews/commentaries), which were included in this systematic review. Experimental studies prove the existence of a kidney-gut axis, focusing on the role of gut-derived uremic toxins and providing concepts that modification of the microbiota composition may result in better AKI outcomes. Small interventional studies in animal models and in humans show promising results, therefore, microbiome-targeted therapy for AKI treatment might be a promising possibility.


2020 ◽  
Vol 9 (8) ◽  
pp. 2521
Author(s):  
Candice Fontaine ◽  
Gwenaelle Jacq ◽  
François Perier ◽  
Mathilde Holleville ◽  
Stephane Legriel

(1) Background: Little is known about the impact of pathophysiological mechanisms that underlie the enhancement of excitotoxicity and the neuronal consequences of status epilepticus (SE), as well as the clinical consequences of secondary brain insults (SBI) in patients with SE on outcome; (2) Methods: Electronic searches were conducted in May 2020 using Medline via PubMed, Embase, and Google Scholar (#CRD42019139092). Experimental studies of animals or randomized, observational, controlled trials of patients with SE in indexed journals were included. There were no language or date restrictions for the published literature included in this review. Information was extracted on study design, sample size, SBI characteristics, and primary and secondary outcomes, including the timing of evaluation; (3) Results: Among the 2209 articles responding to our inclusion criteria, 56 were included in this systematic review. There are numerous experimental data reporting the deleterious effects associated with each of the SBI in animals exposed to SE. In humans, only the effect of target temperature management in hypothermia (32–34 °C) has been explored. (4) Conclusions: There is little experimental evidence that favors the control of secondary brain insult after SE. Further studies are required to assess the neuroprotective interest of secondary brain insult control after SE in humans.


Author(s):  
Carolina Salles de Andrade ◽  
Milena Pereira Pondé

The objective of this study was to conduct a systematic review of experimental studies performed to assess the role of mirror neurons in the pathophysiology of autism. Four papers reported that areas of mirror neurons (MN) were under-active in autistic patients, giving weight to the theory of MN as a cause of ASD. Three papers indicated that MN were activated during the proposed activities, advocating atypical activation of MN, but not necessarily hypoactivation of these areas. One of the articles reported that only part of the MN system or just those areas of interconnected neurons are dysfunctional in autism. Analysis of the selected studies showed a correlation between dysfunction of the mirror neuron system and the main symptoms of autism such as deficits in social cognition, complete absence or a reduction in the individual’s interaction with his/her social environment and a failure in the neural mechanisms of imitation.


2009 ◽  
Vol 8 (3) ◽  
pp. 330-336 ◽  
Author(s):  
Asdrubal Falavigna ◽  
Alisson Roberto Teles ◽  
Maíra Cristina Velho ◽  
Fabrício Diniz Kleber

OBJECTIVE: to conduct a systematic review of experimental and clinical studies evaluating the effect of hyperbaric oxygen therapy on the spinal cord injury. METHODS: ninety-three studies were identified in the database Pubmed. Among these, through a set of inclusion/exclusion criteria, 11 articles published between 1963 and 2009 were selected. In the nine experimental studies, different ways to apply the treatment were observed. The measured outcomes were: functional, histological, biochemical and electrophysiological. RESULTS: in most of the studies, the results show recovery of locomotor function, histology and/or biochemical features. Regarding the two studies in clinical samples, the results are controversial. The samples are heterogeneous and the application of hyperbaric oxygen therapy is not the same for all patients in each study. CONCLUSION: considering the results of this review, further studies are necessary to define the role of hyperbaric oxygen therapy in acute spinal cord injury.


Life Sciences ◽  
2016 ◽  
Vol 151 ◽  
pp. 109-114 ◽  
Author(s):  
Fernando Pereira Carlos ◽  
Vanessa Gradinetti ◽  
Martha Manchini ◽  
Paulo de Tarso Camillo de Carvalho ◽  
José Antonio Silva ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e046817
Author(s):  
Brett Mitchell ◽  
Cassie Curryer ◽  
Elizabeth Holliday ◽  
Claire M Rickard ◽  
Oyebola Fasugba

ObjectiveA systematic review on meatal cleaning prior to urinary catheterisation and post catheterisation and reduces the risk catheter-associated urinary tract infections (CAUTIs) and bacteriuria was published in 2017, with further studies undertaken since this time. The objective of this paper is to present an updated systematic review on the effectiveness of antiseptic cleaning of the meatal area for the prevention of CAUTIs and bacteriuria in patients who receive a urinary catheter.DesignSystematic review.Data sourcesElectronic databases Cochrane Library, PubMed, Embase, The Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline and Academic Search Complete were searched from 1 January 2016 and 29 February 2020.Eligibility criteriaRandomised controlled trials (RCTs) and quasi-experimental studies evaluating the use of antiseptic, antibacterial or non-medicated agents for cleaning the meatal, periurethral or perineal areas before indwelling catheter insertion or intermittent catheterisation or during routine meatal care.Data extraction and synthesisData were extracted using the Cochrane Collaboration’s data collection form for RCTs and non-RCTs. Data were extracted by one researcher and then checked for accuracy by a second researcher.ResultsA total of 18 studies were included. Some potential benefit of using antiseptics, compared with non-antiseptics for meatal cleaning to prevent bacteriuria and or CAUTI was identified (OR 0.84, 95% CI 0.69 to 1.02; p=0.071). Antiseptics (chlorhexidine or povidine-iodine) may be of value for meatal cleaning on the incidence of CAUTI, compared with comparator agents (saline, soap or antimicrobial cloths) (OR=0.65, 95% CI 0.42 to 0.99; p=0.047).ConclusionThere is emerging evidence of the role of some specific antiseptics (chlorhexidine) prior to urinary catheterisation, in reducing CAUTIs, and some potential benefit to the role of antiseptics more generally in reducing bacteriuria.PROSPERO registration numberCRD42015023741.


Sign in / Sign up

Export Citation Format

Share Document