Neural correlates of self-evaluation during puberty
Early adolescence is a time of flux in self-concept and self-esteem, as well as when puberty takes place. However, there is limited research on the neural correlates of self-evaluation in relation to pubertal development. The current study aimed to examine how age and pubertal development associate with neural activation during self-evaluation in a community sample of girls, and if these associations depend on the type of evaluated trait. Participants (N=143; age 10.0-13.0) completed a functional MRI task in which they judged the self-descriptiveness of adjectives describing prosocial, antisocial and social status-related traits. Pubertal development was examined using the self-reported Pubertal Development Scale, and morning salivary testosterone, dehydroepiandrosterone, and estradiol. Contrary to preregistered hypotheses, age and pubertal development were not related to neural activation during self-evaluation. We also examined whether activation in two areas linked to self-referential processing, the ventromedial prefrontal cortex (vmPFC) and perigenual anterior cingulate (pgACC), could predict trial-level self-evaluative behaviour. In line with the preregistered hypothesis, higher vmPFC and pgACC activation during self-evaluation predicted more endorsement of negative items and less endorsement of positive items. Future studies should test longitudinal associations, as well as the predictive value of the neural correlates of self-evaluation for adolescent mental health.