A systematic review and meta-analysis of the association between stress reactivity and psychosis

2021 ◽  
Author(s):  
Pamela Charlotte Jacobsen ◽  
Sarah Muddle ◽  
Bradley Jones ◽  
Gemma Taylor
Keyword(s):  
Emotional Stress ◽  
Stress Reactivity ◽  
Longitudinal Research ◽  
Clinical Symptoms ◽  
Meta Analysis ◽  
Psychotic Symptoms ◽  
Psychotic Experiences ◽  
Cross Sectional ◽  
Related Stress ◽  
Study Designs

Objective: Emotional stress reactivity may be a mediating factor in the association between trauma and psychosis. This review aimed to i) identify, summarise and critically evaluate the link between emotional stress reactivity and psychotic experiences ii) examine evidence for a ‘dose-response’ relationship between stress reactivity and psychosis in the wider psychosis phenotype (i.e. sub-clinical symptoms).Method: Electronic database searches (PsychINFO, MEDLINE, EMBASE) were conducted for studies which investigated the link between stress reactivity and psychosis, psychotic symptoms, or a vulnerability to developing psychosis (wider phenotype). Cross-sectional, experimental and experience sampling method study designs were eligible for inclusion. Results: 45 eligible articles were identified (N participants= 8830). Meta-analysis (k=4, n=383) showed increases in emotional stress reactivity was associated with higher negative affect in response to event-related stress, in those with psychosis compared to controls (mean difference in beta coefficients = 0.05, 95% CI 0.02 to 0.08, p=0.004). However, this difference was small with a considerable degree of heterogeneity (p=.001, I² = 81%) so results should be interpreted with caution. Narrative synthesis showed that increased emotional stress reactivity was associated with psychosis and subclinical psychotic experiences across all study designs, however, findings were inconsistent across studies. Conclusions: The results show emotional stress reactivity is associated with both clinical and subclinical psychosis symptoms. Overall, the evidence suggests that the link between emotional stress reactivity and psychosis and emotional stress reactivity is plausible mediator between trauma and psychosis. Further longitudinal research is needed to assess this.

scholarly journals Psychosocial job stressors and suicidality: a meta-analysis and systematic review

2017 ◽  
Vol 75 (4) ◽  
pp. 245-253 ◽  
Author(s):  
Allison Milner ◽  
Katrina Witt ◽  
Anthony D LaMontagne ◽  
Isabelle Niedhammer
Keyword(s):  
Systematic Review ◽  
Suicide Attempt ◽  
Suicide Ideation ◽  
Longitudinal Research ◽  
Common Mental Disorders ◽  
Job Insecurity ◽  
Meta Analysis ◽  
Job Stressors ◽  
Cross Sectional ◽  
Job Stressor

ObjectivesJob stressors are known determinants of common mental disorders. Over the past 10 years, there has been evidence that job stressors may also be risk factors for suicidality. The current paper sought to examine this topic through the first comprehensive systematic review and meta-analysis of the literature to date.MethodsWe used a three-tier search strategy of seven electronic databases. Studies were included if they reported on a job stressor or job-related stress as an exposure and suicide ideation, self-harm, suicide attempt or suicide as an outcome. Two researchers independently screened articles. All extracted effect estimates were converted to log-transformed ORs.ResultsThere were 22 studies that were included in meta-analysis. Overall, exposure to job stressors was associated with elevated risk of suicide ideation and behaviours. The OR for suicide ideation (14 studies) ranged from 1.45 (95% CI 1.01 to 2.08) for poor supervisor and colleague support to 1.91 (95% CI 1.22 to 2.99) for job insecurity. For suicide (six studies), exposure to lower supervisor and collegial support produced an OR of 1.16 (95% CI 0.98 to 1.38), while low job control resulted in an OR of 1.23 (95% CI 1.00 to 1.50). There were only two studies that examined suicide attempt, both of which suggested an adverse effect of exposure to job stressors.ConclusionsThis study provides some evidence that job stressors may be related to suicidal outcomes. However, as most studies in the area were cross-sectional and observational in design, there is a need for longitudinal research to assess the robustness of observed associations.

scholarly journals Association between soft drinks consumption and asthma: a systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e029046 ◽  
Author(s):  
Abdulmohsen Hamdan Al-Zalabani ◽  
Ibrahim Noor Elahi ◽  
Abdullah Katib ◽  
Abdulmajeed G Alamri ◽  
Abdulrahman Halawani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prenatal Exposure ◽  
Longitudinal Research ◽  
Meta Analysis ◽  
Soft Drinks ◽  
Observational Research ◽  
Cochrane Library ◽  
Asthma Prevalence ◽  
Cross Sectional ◽  
Cross Sectional Studies

ObjectivesTo carry out meta-analysis and systematic review on the association between soft drinks consumption and asthma prevalence among adults and children.DesignSystematic review and meta-analysis of observational research.Data sourcesMedline, Scopus, ISI Web of Science and the Cochrane Library were searched up to December 2018.Eligibility criteriaWe included observational studies investigating the association between soft drinks consumption (including maternal consumption during pregnancy) and asthma or wheeze.Data extraction and synthesisData were extracted by one author and reviewed independently by two other authors. The most adjusted estimate from each original study was used in the meta-analysis. Meta-analysis was conducted using random-effects model. The quality of studies was assessed using the Newcastle–Ottawa scale and heterogeneity was evaluated using I2statistic.ResultsOf 725 publications originally identified, 19 were included in this systematic review, including 3 cohort studies and 16 cross-sectional studies. Ten articles reported on children up to 18 years, 5 articles on adults (>18 years) and 2 articles on prenatal exposure. In total, 468 836 participants were included, with more than 50 000 asthma cases. Soft drinks consumption was associated with significantly increased odds of asthma in both adults (OR=1.37; 95% CI, 1.23 to 1.52) and children (OR=1.14; 95% CI, 1.06 to 1.21). Prenatal exposure had marginally statistically significant association (OR=1.11; 95% CI, 1.00 to 1.23) with asthma in children. In subgroup analysis for childhood exposure, the association persists for sugar-sweetened soft drinks but not for carbonated drinks.ConclusionOur findings show a positive association between soft drinks consumption and asthma prevalence, mostly from cross-sectional studies. Therefore, more longitudinal research is required to establish causality.

scholarly journals Cyberbullying Perpetration and Victimization in Youth: A Meta-Analysis of Longitudinal Studies

2020 ◽  
Vol 25 (2) ◽  
pp. 163-181 ◽  
Author(s):  
Laura Marciano ◽  
Peter J Schulz ◽  
Anne-Linda Camerini
Keyword(s):  
Longitudinal Studies ◽  
Behavioral Problems ◽  
Internet Use ◽  
Longitudinal Research ◽  
Meta Analysis ◽  
Sample Population ◽  
Related Factors ◽  
Cross Sectional ◽  
Meta Analyses ◽  
Over Time

Abstract Cyberbullying perpetration (CP) and victimization (CV) are prevalent issues in adolescent development. However, previous meta-analyses focused only on cross-sectional findings. The present study aims to meta-analytically summarize 56 longitudinal studies on CP, CV, and related factors in children and adolescents. Forty meta-analyses on CP and CV as both predictors and outcomes of person-related, Internet activity-related, and contextual factors were performed. Additional moderator analyses took into account study design, sample population, and quality of the studies. Results highlight reciprocal longitudinal effects among CP, CV, and both traditional bullying and victimization: CP causes externalizing problem behaviors over time, whereas CV constitutes a risk factor of internalizing problems, such as depression and anxiety. Conversely, behavioral problems and increased Internet use predict involvement in CP, while depression, anxiety, and Internet use also predict CV over time. Further longitudinal research is needed to provide empirical evidence on understudied concepts.

scholarly journals Loot boxes: A scoping review on primary studies of prevalence and association with problematic gaming and gambling

2021 ◽  
Author(s):  
Irene Montiel Juan ◽  
Aránzazu Basterra-González ◽  
Juan Manuel Machimbarrena ◽  
Jessica Ortega-Barón ◽  
Joaquín González-Cabrera
Keyword(s):  
Scoping Review ◽  
Longitudinal Research ◽  
Meta Analysis ◽  
Future Research ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Scoping Reviews ◽  
Problematic Gaming ◽  
General Studies ◽  
Actual Prevalence

Background: Loot boxes are a type of random microtransactions that are increasingly common in videogames, so there is some concern about its true extent and entailed risks. Although many papers have been published recently about this topic, the actual prevalence of loot boxes use is uncertain and there is still controversy over the nature of its relationship with problematic gaming and gambling. Objectives: The aims of this scoping review are to summarize the characteristics and findings of published primary research studies about the prevalence of loot boxes and/or its relationship with problematic gaming and gambling, taking into account the operationalization of loot boxes use in these studies. Methods: The Joanna Briggs Institute Guidance for conducting a systematic scoping reviews and the systematic reviews and meta-analysis extension for scoping reviews (PRISMA-ScR) are followed. Searches in three academic databases provided 299 articles. Results: Sixteen primary studies met the inclusion criteria for this review. All the studies were cross-sectional, only four used samples of adolescents and males were overrepresented in ten of the samples. The annual purchase prevalence rate in gamers is higher in adults than in adolescents (22.7 - 44.2% and 20 - 33.9%, respectively), but in general samples (gamers and non-gamers) it is just the opposite (from 24.9% among 13-14 to 7.8% in adults). Prevalence rates are also higher in the samples made up of gamers and gamblers and in studies that measured monthly or lifetime prevalence. In general, studies suggest a positive and significant relationship between loot boxes and problematic gaming and gambling. Conclusions: The overrepresentation of male adults with gaming and/or gambling problems in study samples do not allow to generalize their results. An enhanced standardization in measurements and methods for future research in this field is recommended. Also, further longitudinal research is needed to improve the understanding of these problems.

scholarly journals Adiponectin and Sarcopenia: A Systematic Review With Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Klara Komici ◽  
Antonio Dello Iacono ◽  
Antonio De Luca ◽  
Fabio Perrotta ◽  
Leonardo Bencivenga ◽  
...  
Keyword(s):  
Systematic Review ◽  
Longitudinal Research ◽  
Meta Analysis ◽  
Asian Population ◽  
Female Gender ◽  
Endocrine Function ◽  
Current Evidence ◽  
Cochrane Library ◽  
Cross Sectional ◽  
Inflammatory Status

BackgroundSarcopenia is a progressive loss of skeletal muscle mass whose pathophysiology has been proposed to possibly involve mechanisms of altered inflammatory status and endocrine function. Adiponectin has been shown to modulate inflammatory status and muscle metabolism. However, the possible association between adiponectin levels and sarcopenia is poorly understood. In order to fill this gap, in the present manuscript we aimed to summarize the current evidence with a systematic review and a meta-analysis of studies reporting serum adiponectin levels in patients with sarcopenia compared to non-sarcopenic controls.MethodsAn electronic search through Medline/PubMed, Cochrane Library, and Science Direct was performed till March 1, 2020. From the included papers, meta-analysis of cross-sectional studies comparing serum levels of adiponectin between patients with sarcopenia and controls was performed.ResultsOut of 1,370 initial studies, seven studies were meta-analyzed. Sarcopenic participants had significantly higher levels of adiponectin Hedges’ g with 95% confidence interval (CI): 1.20 (0.19–2.22), p = 0.02 than controls. Subgroup analysis, performed in Asian population and focused on identification of the condition based on AWGS criteria, reported higher adiponectin levels in sarcopenic population (2.1 (0.17–4.03), p = 0.03 and I2 = 98.98%. Meta-regression analysis revealed female gender to significantly influence the results as demonstrated by beta = 0.14 (95% CI (0.010–0.280), p = 0.040).ConclusionsOur meta-analysis found evidence that sarcopenia is associated with higher adiponectin levels. However, caution is warranted on the interpretation of these findings, and future longitudinal research is required to disentangle and better understand the topic.

scholarly journals Ecological Momentary Assessment: A Meta-Analysis on Designs, Samples, and Compliance Across Research Fields

Assessment ◽  
2022 ◽  
pp. 107319112110675
Author(s):  
Cornelia Wrzus ◽  
Andreas B. Neubauer
Keyword(s):  
Financial Incentives ◽  
Longitudinal Research ◽  
Meta Analysis ◽  
Dropout Rate ◽  
Total N ◽  
Research Fields ◽  
Sample Characteristics ◽  
Ecological Momentary ◽  
Study Designs ◽  
Predict Study

Ecological Momentary Assessments (i.e., EMA, repeated assessments in daily life) are widespread in many fields of psychology and related disciplines. Yet, little knowledge exists on how differences in study designs and samples predict study compliance and dropout—two central parameters of data quality in (micro-)longitudinal research. The current meta-analysis included k = 477 articles (496 samples, total N = 677,536). For each article, we coded the design, sample characteristics, compliance, and dropout rate. The results showed that on average EMA studies scheduled six assessments per day, lasted for 7 days, and obtained a compliance of 79%. Studies with more assessments per day scheduled fewer assessment days, yet, the number of assessments did not predict compliance or dropout rates. Compliance was significantly higher in studies providing financial incentives. Otherwise, design or sample characteristics had little effects. We discuss the implications of the findings for planning, reporting, and reviewing EMA studies.

scholarly journals Clinical and Paraclinical Characteristics of COVID-19 patients: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Keyvan Heydari ◽  
Sahar Rismantab ◽  
Amir Shamshirian ◽  
Parisa Lotfi ◽  
Nima Shadmehri ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Symptoms ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Case Series ◽  
Ground Glass Opacity ◽  
Border Crossings ◽  
Cross Sectional ◽  
Public Places

IntroductionRecently, a new strain of coronaviruses, which originated from Wuhan City, Hubei Province, China has been identified. According to the high prevalence of new coronavirus, further investigation on the clinical and paraclinical features of this disease seems essential. Hence, we carried out this systematic review and meta-analysis to figure out the unknown features.MethodsThis study was performed using databases of Web of Science, Scopus and PubMed. We considered English cross-sectional and case-series papers which reported clinical, radiological, and laboratory characteristics of patients with COVID-19. We used STATA v.11 and random effect model for data analysis.ResultsIn the present meta-analysis, 32 papers including 49504 COVID-19 patients were studied. The most common clinical symptoms were fever (84%), cough (65%) and fatigue (42%), respectively. The most common radiological and paraclinical features were bilateral pneumonia (61%), ground-glass opacity (50%), thrombocytopenia (36%) and lymphocytopenia (34%). The study also showed that the frequency of comorbidities and early symptoms was higher in critically severe patients. Moreover, we found the overall mortality rate of three percent.ConclusionAccording to that there are many cases without Computed Tomography Scan findings or clear clinical symptoms, it is recommended to use other confirming methods such RNA sequencing in order to identification of suspicious undiagnosed patients. Moreover, while there is no access to clinical and paraclinical facilities in in public places such as airports and border crossings, it is recommended to consider factors such as fever, cough, sputum and fatigue.

scholarly journals Perceived Paternal and Maternal Parenting Attributes among Chinese Adolescents: A Meta-Analysis

2020 ◽  
Vol 17 (23) ◽  
pp. 8741
Author(s):  
Diya Dou ◽  
Daniel T. L. Shek ◽  
Ka Ho Robin Kwok
Keyword(s):  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Chinese Adolescents ◽  
Cross Sectional ◽  
Maternal Parenting ◽  
Effect Model ◽  
Paternal Parenting ◽  
Study Designs ◽  
Parental Differences

This meta-analysis study examined perceived parental differences between Chinese mothers and fathers from the perspective of adolescents. A systematic search for relevant articles published up to 2019 was performed in electronic databases. The random-effect model was used to calculate the weighted and pooled effect size at the 95% confidence interval. This study was based on 43 studies in English peer-reviewed journals involving 55,759 Chinese adolescents aged between 11 and 18 years. We conducted subgroup analyses to explore whether differences in study designs (i.e., cross-sectional and longitudinal) and adolescent gender could explain perceived parental differences. The results showed that perceived maternal parenting attributes were more positive than perceived paternal parenting attributes in cross-sectional and longitudinal studies. Besides, perceived paternal parenting attributes showed slightly greater variability than did maternal parenting attributes. Subgroup analysis based on adolescent gender revealed that only adolescent girls perceived maternal parenting attributes to be more positive than paternal parenting attributes.

Cannabis use at a young age is associated with psychotic experiences

2010 ◽  
Vol 41 (6) ◽  
pp. 1301-1310 ◽  
Author(s):  
C. D. Schubart ◽  
W. A. van Gastel ◽  
E. J. Breetvelt ◽  
S. L. Beetz ◽  
R. A. Ophoff ◽  
...  
Keyword(s):  
Negative Symptoms ◽  
Psychiatric Symptoms ◽  
Adult Population ◽  
Population Sample ◽  
Cannabis Use ◽  
Psychotic Symptoms ◽  
Psychotic Experiences ◽  
Cross Sectional ◽  
Symptom Dimensions ◽  
The Impact

BackgroundCannabis use is associated with psychosis and a range of subclinical psychiatric symptoms. The strength of this association depends on dosage and age at first use. The current study investigates whether level of cannabis exposure and starting age are associated with specific profiles of subclinical symptoms.MethodWe collected cross-sectional data from a young adult population sample by administering an online version of the Community Assessment of Psychic Experiences (CAPE). Cannabis exposure was quantified as the amount of Euros spent on cannabis per week and the age of initial cannabis use. The primary outcome measure was the odds ratio (OR) to belong to the highest 10% of scores on the total CAPE and the positive-, negative- and depressive symptom dimensions.ResultsIn 17 698 adolescents (mean age 21.6, s.d.=4.2 years), cannabis use at age 12 years or younger was strongly associated with a top 10% score on psychotic experiences [OR 3.1, 95% confidence interval (CI) 2.1–4.3] and to a lesser degree with negative symptoms (OR 1.7, 95% CI 1.1–2.5). The OR of heavy users (>€25/week) for negative symptoms was 3.4 (95% CI 2.9–4.1), for psychotic experiences 3.0 (95% CI 2.4–3.6), and for depressive symptoms 2.8 (95% CI 2.3–3.3).ConclusionsEarly start of cannabis use is strongly associated with subclinical psychotic symptoms and to a lesser degree with negative symptoms, while smoking high amounts of cannabis is associated with increased levels of all three symptom dimensions: psychotic, negative and depressive. These results support the hypothesis that the impact of cannabis use is age specific.

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