scholarly journals Burden and risk factors of preterm birth in Nasarawa State, North Central, Nigeria: A five-year case review

2021 ◽  
Vol 7 (2) ◽  
pp. 36-41
Author(s):  
Ikrama Hassan ◽  
◽  
Surajudeen Bello ◽  
Michael Anazodo ◽  
Abdulmumuni Ahmed Lawal ◽  
...  

Background: Preterm birth has been on the increase globally and accounting for morbidities and mortalities. Preterm delivery referred to the birth of a newborn prior to thirty seven completed gestational weeks. There is dearth of knowledge on the burden of preterm birth in this state. This study therefore determined the burden of preterm deliveries in Nasarawa State, evaluate the risk factors and identify the outcome of such deliveries. Methods: A descriptive cross-sectional study of all preterm delivered from the 1st of January 2014 to the 31st of December 2013 at the Dalhatu Araf Specialist Hospital (DASH) Lafia, General Hospital Akwanga and Medical Centre Mararaba Gurku in the Southern, Northern and Western senatorial zones of Nasarawa State respectively. Data was analyzed using SPSS version 20. Results: The mean age of mothers of preterm in this study is 26.5±5.7 years. More than three-quarter of preterm birth in Nasarawa State were at the DASH Lafia. The prevalence of preterm birth and admissions were 1.5% and 10.8% respectively. One in four of the preterm were either late preterm or extreme preterm. Singleton gestation accounted for 82.1% of the preterm births while 75.6% of such deliveries where through the vaginal mode of deliveries. Risk factors for preterm deliveries were multiple gestation, antepartum haemorrhage (placenta previa), premature rupture of membrane and previous preterm delivery. Deaths among the preterm was 11% in this study. Conclusion: The burden of preterm births in this study is comparable to other centre in same region. Half of the preterm were either late or extreme preterm. Risk factors for preterm deliveries were placenta previa, premature rupture of membrane, multiple gestation and previous preterm child birth. Death was recorded in one out of every nine preterm

2021 ◽  
Vol 49 (8) ◽  
pp. 030006052110346
Author(s):  
Techane Sisay Tuji ◽  
Addisu Dabi Wake ◽  
Gezahegn Badeg Adere ◽  
Aselefu Beka Wedajo ◽  
Batu Dekeba Obole ◽  
...  

Objective To assess the prevalence of spontaneous preterm births and to identify the associated risk factors. Methods This single-centre cross-sectional study enrolled women that experienced a preterm birth as registered on the neonatal log-book between 30 December 2019 and 30 December 2020. A pre-tested structured checklist was used to collect data (sociodemographic characteristics; obstetric-related factors; medical history; and pregnancy-related factors). Bivariate logistic regression analyses were applied to identify factors associated with spontaneous preterm birth. A multivariate model identified significant independent risk factors. Results A total of 310 patients participated in the study. The prevalence of spontaneous preterm birth in this population was 67.1% (208 of 310; 95% confidence interval [CI] 61.5, 71.9). Patients without a partner (adjusted odds ratio [AOR] = 1.470, 95% CI 1.23, 4.42), patients residing in a rural area (AOR = 2.51, 95% CI 1.123, 5.513) and those with a history of PIH during their current pregnancy (AOR = 0.104, 95% CI 0.053, 0.014) were significantly more likely to have a spontaneous preterm birth. Conclusion The prevalence of spontaneous preterm birth in in this study was high. Healthcare providers and all stakeholders should focus on screening pregnant women at the risk of spontaneous preterm birth.


2021 ◽  
Vol 23 (2) ◽  
pp. 179-184
Author(s):  
Upanish Oli ◽  
Radhika Upreti ◽  
Neebha Ojha ◽  
Meeta Singh

Preterm birth (PTB) is one of the major causes of morbidity in newborn. The aim of this study was to estimate the prevalence and to compare the associated risk factors of early and late PTB. This was a hospital-based cross sectional study conducted in 2016/2017. Women, 271, having PTB at 28-33+6 weeks period of gestation was taken as early PTB and 34-36+6 were taken as late PTB. Data was collected using semi-structured questionnaire, patients’ record book, adopting face- to - face interview technique and clinical examination. The annual prevalence of PTB was 7.25% of which 11% were <28+0 weeks, early PTB was 32% and late PTB was 57%. Mother with school education were 2.0 times more likely to have early preterm births than those having higher education (P-value: 0.005, COR: 2.061,95% CI:1.234-3.441). Mothers with positive history of PTB in any of previous pregnancy was 10.7 times more likely to have early PTB in current pregnancy (P-value: <0.001, COR: 10.677, 95% CI: 2.792 – 40.746). Both variables were found to have independent risk on early PTB in logistic regression analysis (education: P-value: 0.027, aOR: 2.973, 95% CI: 1.132- 3.047; previous history of PTB: P-value: 0.002, aOR: 9.191, 95% CI: 2.308 - 36.596). Early and late PTB have differential risk factors. Mothers with positive history of PTB and having lower level of education were more likely to have early PTB.


BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e024143 ◽  
Author(s):  
Carley Riley ◽  
Brita Roy ◽  
Jeph Herrin ◽  
Erica Spatz ◽  
Mark T Silvestri ◽  
...  

ObjectiveTo determine if preterm birth, defined as gestational age <37 weeks, is lower for women living in counties with higher well-being, after accounting for known individual risk factors.DesignCross-sectional study of all US births in 2011.ParticipantsWe obtained birth data from the National Center for Health Statistics which included 3 938 985 individuals.Main outcomes measuresPrimary outcome measure was maternal risk of preterm delivery by county; primary independent variable was county-level well-being as measured by the Gallup-Sharecare Well-Being Index (WBI).ResultsWomen living in counties with higher population well-being had a lower rate of preterm delivery. The rate of preterm birth in counties in the lowest WBI quintile was 13.1%, while the rate of preterm birth in counties in the highest WBI quintile was 10.9%. In the model adjusted for maternal risk factors (age, race, Hispanic ethnicity, smoking status, timing of initiation of prenatal visits, multiparity, maternal insurance payer), the association was slightly attenuated with an absolute difference of 1.9% (95% CI 1.7% to 2.1%; p<0.001).ConclusionsPregnant women who live in areas with higher population well-being have lower risk of preterm birth, even after accounting for individual risk factors.


Author(s):  
Veronika Günther ◽  
Ibrahim Alkatout ◽  
Alexandra Stein ◽  
Nicolai Maass ◽  
Alexander Strauss ◽  
...  

Abstract According to the World Health Organization, smoking is the most important risk factor for adverse pregnancy outcomes in industrialized nations. We aimed to establish how fetal gender and smoking interact with regard to perinatal outcomes, especially preterm delivery. Data from 220,339 singleton pregnancies, obtained from the German Perinatal Survey in Schleswig-Holstein and registered between 2004 and 2017 were analyzed in regard to smoking behavior, fetal gender, and preterm delivery. The rate of preterm births was directly proportional to the women’s consumption of nicotine. The rate of preterm deliveries was 6.8% among nonsmokers, and 13.2% in women who were very heavy smokers (≥22 cigarettes/day). Very heavy smoking (≥22 cigarettes/day) had a marked impact on extremely preterm births (<28 weeks of gestation) and very preterm births (28–31 weeks of gestation). Preterm births increased by 1.2% from heavy smokers to very heavy smokers; the differences between the other groups ranged between 0.1% and 0.4%. Fetal gender also had an impact on preterm birth: male infants were predominant in nearly all groups of women who delivered preterm infants. Smoking during pregnancy and male gender are both risk factors for preterm delivery. Fetal gender should be given greater attention as one of the several risk factors of preterm birth. Due to the high rate of morbidity among preterm infants and enormous costs for the healthcare system, women should be encouraged to cease or at least reduce smoking during pregnancy.


Author(s):  
Trupti Ruge ◽  
Trupti Ruge ◽  
Emanuel Gracias

Introduction: Preterm birth is childbirth occurring at less than 37 completed weeks or 259 days of gestation, is a major determinant of neonatal mortality and morbidity and has long-term adverse consequences for health. Identifying ways to address preventable causes of preterm birth should be a top priority in developing regions of the world. the present study was planned to find the association between cervical length at 18 to 23 weeks of gestation done as a routine during all second level scans and spontaneous preterm delivery. Patients and Methods: This is a hospital based cross sectional study conducted during the period from January 2019 to December 2019. A total of 205 women presenting with singleton pregnancies between 18- 23 weeks of gestations were assessed by transvaginal ultrasound for the measurement of cervical length. Patients were interviewed and their demographic data such as age, obstetric index(GPALD), obstetric history such last menstrual period (LMP), estimated delivery date (EDD) and current pregnancy details such as BP, pulse rate, pallor, period of gestation, were recorded in a predesigned pro forma. Results: In a total of 205 subjects, the average age was found to be 23.26 ± 3.49 years with 52.2% of the women being primigravida. The mean gestation age at the time of enrollment was 20.72 ± 1.00 weeks with 33% of women showing a cervical length of 26-30 mm. The delivery outcome was found as 11% preterm, majority (89.27%) was term delivery. Conclusion: The present study showed that a significantly higher number of women with cervical length ≤ 30 mm (assessed at 18 to 23 weeks of gestation) had preterm labour compared to a woman with cervical length > 30 mm.


2019 ◽  
pp. 143-149

Factores de riesgo asociados al parto pre término en el hospital nacional Guillermo Almenara Irigoyen de enero a junio del 2010. Risk factors associated with preterm delivery in the Guillermo Almenara Irigoyen National Hospital from January to June 2010 Lizbeth Estefanía Díaz Polo Universidad de San Martin de Porres. Lima 12 DOI: https://doi.org/10.33017/RevECIPeru2011.0036/ RESUMEN El parto pre término ocurre entre las 22 y antes de las 37 semanas. Su etiología es multifactorial y es causa principal de morbilidad y mortalidad perinatal. El objetivo fue determinar los factores de riesgo asociados al parto pre término en gestantes del Hospital Nacional Guillermo Almenara Irigoyen de Enero a Junio del 2010. Se realizó un estudio retrospectivo, caso - control y descriptivo. Las historias clínicas de pacientes casos y controles, fueron revisadas y registradas en fichas y se procesaron con el SPSS versión 15. Los resultados fueron 81 pacientes con diagnóstico de parto pre término, con significancia estadística en las siguientes variables: ausencia de atención prenatal (OR 3.07, P>0.05), pre eclampsia (OR 20.86, P>0.001), ruptura prematura de membranas (OR 4.03, P>0.005), embarazo múltiple (OR 5.64, P>0.01), corioamnionitis (OR 2.02, P>0.1), lugar de nacimiento: sierra (OR 3.88, P>0.05) y nivel socioeconómico D-E (OR12.73, P>0.05). Se evidencio que gestantes más pobres y con menor nivel educativo presentan mayor incidencia de parto pre término [1] [2] [3]. Que el 21% de los partos pre término, estuvo asociado a la ruptura prematura de membranas (OR 4.03) dato que se encuentra dentro del rango de incidencia, ya que Aagaard-Tillery [4] (2005) señala una incidencia de la ruptura prematura de membrana pre término entre 30 y 40% y Fabián (2008) observó 11.67% de ruptura prematura de membranas [5]. Las gestantes con pre eclampsia tuvieron un riesgo 20 veces más de presentar parto pre término. El 34.6% con parto pre término presentó pre eclampsia, de ellas el 42.8% fue pre eclampsia severa, 25% leve y 32.14% síndrome de HELLP; dato similar al observado por Salviz en su estudio en el Hospital Cayetano Heredia, donde encontró un 30 % de parto pre término en pacientes con pre eclampsia; si bien es conocido que la pre eclampsia afecta del 3 al 5% de las gestaciones, no existen estudios sobre la incidencia de la pre eclampsia en el parto pre término [6]. Se concluye que el principal factor de riesgo asociado al parto pre término fue la pre eclampsia. Haber nacido en la sierra, pertenecer a nivel socioeconómico D-E, ausencia de atención prenatal, ruptura prematura de membranas, coriomanionitis y embarazo múltiple fueron también significativos. Descriptores: factores de riesgo, parto pre término, parto a término, pre eclampsia. ABSTRACT Preterm birth occurs between 22 and before 37 weeks. Its etiology is multifactorial and is a major cause of perinatal morbidity and mortality. The objective was to determine the risk factors associated with preterm delivery in pregnant women Guillermo Almenara Irigoyen National Hospital from January to June 2010. We performed a retrospective case - control and descriptive. The case histories of patients and controls were reviewed and recorded in chips and processed with SPSS version 15. The results were 81 patients diagnosed with preterm birth, with statistical significance in the following variables: absence of prenatal care (OR 3.07, P> 0.05), pre-eclampsia (OR 20.86, P <0.001), premature rupture of membranes (OR 4.03, P> 0,005), multiple pregnancy (OR 5.64, P> 0.01), chorioamnionitis (OR 2.02, P> 0.1), place of birth: saw (OR 3.88, P> 0.05) and socioeconomic status (OR12.73, P> 0.05). It was evident that more poor pregnant women with less education have a higher incidence of preterm delivery [1] [2] [3]. That 21% of preterm births was associated with premature rupture of membranes (OR 4.03) data that is within the range of incidence, as Aagaard-Tillery [4] (2005) noted an incidence of premature rupture preterm membrane between 30 and 40% and Fabian (2008) observed 11.67% of premature rupture of membranes [5]. Pregnant women with preeclampsia had a 20 times higher risk of preterm birth present. 34.6% presented with preterm birth pre-eclampsia, of which 42.8% was severe preeclampsia, 25% and 32.14% mild HELLP syndrome; data Salviz similar to that observed in their study in the Cayetano Heredia Hospital, where he found a 30 % of preterm birth in patients with preeclampsia, although it is known that pre-eclampsia affects 3 to 5% of pregnancies, no studies on the incidence of preeclampsia in preterm labor [6]. We conclude that the main risk factor associated with preterm delivery was preeclampsia. Being born in the mountains, belong to socioeconomic status, lack of prenatal care, premature rupture of membranes, coriomanionitis and multiple pregnancy were also significant. Keywords: risk factors, preterm delivery, term delivery, pre-eclampsia.


2019 ◽  
Vol 26 (12) ◽  
pp. 2044-2047
Author(s):  
Faraz Ahmed ◽  
Mohsin Ali ◽  
Hussan Ali Sarwar ◽  
Miqdad Haider ◽  
Muhammad Bilal Safdar ◽  
...  

One of the major and important but preventable causes of neonatal morbidity and mortality is Neonatal sepsis. Objectives: To determine the frequency of maternal risk factors in diagnosed cases of early neonatal sepsis. Study Design: Descriptive cross sectional study. Setting: Nursery, Department of Children Hospital and the institute of child health, Lahore. Period: 15-01-2016 to 15-07-2016. Material and Methods: After approval from hospital ethical committee, according to inclusion and exclusion criteria, 250 patients were enrolled in the study from nursery department of children hospital, Lahore. Maternal risk factors i.e. PROM, meconium stained liquor and preterm delivery were recorded along with the demographic information of each case. Results: In our study, out of 250 cases, cases between 1-2 days were 64.8% (n=162) while cases between 3 days of life were 35.2% (n=88), mean+sd was resulted as 2.17+0.69 days. Frequency of maternal risk factors in diagnosed cases of early neonatal sepsis was turned out as 64.8% (n=162) PROM, 29.6% (n=74) meconium stained liquor and preterm delivery was resulted in 21.2% (n=53). Conclusion: The leading maternal risk factor is PROM followed by meconium stained liquor and preterm delivery in diagnosed cases of early neonatal sepsis.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Dwiana Ocviyanti ◽  
William Timotius Wahono

Background. Premature rupture of the membrane (PROM) is associated with high maternal as well as perinatal morbidity and mortality risks. It occurs in 5 to 10% of all pregnancy while incidence of amniotic membrane infection varies from 6 to 10%. This study aimed to determine the incidence of neonatal sepsis in Cipto Mangunkusumo Hospital and the risk factors. Methods. A cross-sectional study was done in Cipto Mangunkusumo Hospital, Jakarta, from December 2016 to June 2017. The study used total sampling method including all pregnant women with gestational age of 20 weeks or more experiencing PROM, who came to the hospital at that time. Samples with existing comorbidities such as diabetes mellitus or other serious systemic illnesses such as heart disease or autoimmune condition were excluded from the analysis. Results. A total of 405 pregnant women with PROM were included in this study. There were 21 cases (5.2%) of neonatal sepsis. The analysis showed that risk of neonatal sepsis was higher in pregnant women with prolonged rupture of membrane for ≥ 18 hours before hospital admission (OR 3.08), prolonged rupture of membrane for ≥ 15 hours during hospitalization (OR 7.32), and prolonged rupture of membrane for ≥ 48 hours until birth (OR 5.77). The risk of neonatal sepsis was higher in preterm pregnancy with gestational age of <37 weeks (OR 18.59). Conclusion. Risk of neonatal sepsis is higher in longer duration of prolonged rupture of membrane as well as preterm pregnancy.


2020 ◽  
Vol 32 (2) ◽  
pp. 90-93
Author(s):  
Mst Afroza Khanum ◽  
Salma Lavereen ◽  
Moniruzzaman ◽  
Romana

Background: Currently preterm labour is one of the most challenging problems confronting the obstetricians and perinatologists. This unfortunate episode accounts for 50-75% of the perinatal mortality. Methods: A cross sectional study was conducted on 210 pregnant women with preterm labour admitted in Monno Medical College Hospital, Manikganj from June 2014 to December 2015, to study the causes and outcome of preterm birth in Tertiary health centre of Manikganj. Results: Occurence of preterm birth was 13.82%; 47.14% occured between 34-37 weeks of gestation; 33.80% occured 31-33 weeks of gestation and occurred in 28-30 weeks 19.04%. About 22% patients presenting with preterm labour had a past history of abortions and 14.3% had a history of preterm delivery. Premature rupture of membranes was found to be the most common risk factor related with preterm labour in the present pregnancy. Genitourinary tract infection was the next important risk factor of preterm labour; 24.8% (86) patients had either vaginal infection (19.5%) or urinary infection (21.4%) or both. Another important risk factor identified in this study was antepartum haemorrage which was cause in 11.4 % cases. Preterm babies commonly suffered from various complications like jaundice (32.1%), respiratory distress syndrome (22.6%), asphyxia (13.5%), sepsis, hypoglycemia and coagulopathy. Conclusion: Most of the preterm births occured between 34-37 weeks of gestation. Most common risk factors of preterm births are history of abortion and preterm delivery in previous pregnancy; PROM UTI vaginal infection, PIH and APH in correct pregnancy. Newborn jaundice, RDS and birth asphyxia are the common neonatal morbidity in preterm labour. Identifying risk factors to prevent the onset of preterm labour and advanced neonatal care unit can help decrease neonatal morbidity and mortality. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 90-93


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