O668 ANALYSIS OF RISK FACTORS, MATERNAL AND FETAL OUTCOME OF SPONTANEOUS PRETERM PREMATURE RUPTURE OF MEMBRANES: A CROSS SECTIONAL STUDY

2012 ◽  
Vol 119 ◽  
pp. S496-S496
Author(s):  
S.M. Surekha ◽  
C. Thippeveeranna ◽  
K.P. Devi ◽  
B. Devi ◽  
C.M. Singh
Keyword(s):  
Risk Factors ◽  
Fetal Outcome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Preterm Premature Rupture

scholarly journals Analysis of risk factors, maternal and fetal outcome of spontaneous preterm premature rupture of membranes: a cross sectional study

2017 ◽  
Vol 6 (9) ◽  
pp. 3781
Author(s):  
Surekha S. Mohan ◽  
Chamaraja Thippeveeranna ◽  
Naorem N. Singh ◽  
Laiphrakpam R. Singh
Keyword(s):  
Fetal Outcome ◽  
Cross Sectional Study ◽  
Perinatal Morbidity ◽  
Sectional Study ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Membrane Rupture ◽  
Preterm Premature Rupture ◽  
History Of

Background: Preterm premature rupture of membranes (PPROM) is one of the most common complications of pregnancy. It is an important cause of perinatal morbidity and mortality. Objective of present study was to determine incidence, risk factors, maternal, fetal outcome of PPROM occurring in patients attending a tertiary hospital in North Eastern India.Methods: This descriptive cross- sectional study was carried out in the department of Obstetrics and Gynecology, Regional Institute of Medical Sciences, Imphal, India. Out of 15,969 deliveries between July 2010 to December 2011, 358 pregnant patients with spontaneous preterm premature rupture of membranes from 28-0 to 36-6weeks gestation were reviewed. After excluding patients with uterine anomalies, intrauterine deaths and congenital anomalies 293 patients were included and evaluated in this study.Results: The incidence of PPROM was 2.2%. Out of 293 patients 86% were singleton pregnancies, 12.9% were twins and 1.02% were triplets. 48.4% had previous history of termination of pregnancy, 28.6% history of previous PPROM and 16.3% had urinary tract infection. The mean gestational age at the onset of membrane rupture was 34.1+2.4 weeks and the latency from the membrane rupture to delivery interval ranged from 0-72 days with a mean of 48.4 hours. There were 7stillbirths (2.38%) and 4 neonatal deaths (1.02%) resulting in perinatal deaths of 3.29% and perinatal mortality rate of 0.329 per 1000 births due to PPROM. Maternal morbidity was minimal with postpartum haemorrhage in 11 patients (4.1%), abruptio placentae in 7 patients (2.3%) and sepsis in 43patients (14.6%). 66 patients (22.5%) underwent caesarean section for which malpresentations were the major cause.Conclusions: Despite remarkable advances in perinatal care, preterm premature rupture of membranes continues to cause perinatal morbidity and mortality. Strategies should be developed for its prevention. Management protocol should be improved in regard to vaginal swab culture and use of specific antibiotics.

scholarly journals Predictors of Premature Rupture of Membranes among Pregnant Women in Rural Uganda: A Cross-Sectional Study at a Tertiary Teaching Hospital

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Simon Byonanuwe ◽  
Emmanuel Nzabandora ◽  
Baltazar Nyongozi ◽  
Theophilus Pius ◽  
David Santson Ayebare ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Pregnant Women ◽  
Gestational Age ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
History Of ◽  
Tract Infections

Background. Premature rupture of membranes (PROM) is a common condition in developed and developing countries and poses a serious threat to the maternal and fetal well-being if not properly managed. This study delineated the prevalence and predictors of PROM in the western part of Uganda so as to guide specific preventive measures. Methods. A cross-sectional study design was conducted in the months of September 2019 to November 2019. A total of 334 pregnant women above 28 weeks of gestation admitted at the maternity ward of KIU-TH were consecutively enrolled. Interviewer-administered questionnaires were used to obtain the data. Descriptive statistics followed by binary logistic regression were conducted. All data analyses were conducted using STATA 14.2. Results. Of the 334 pregnant women enrolled, the prevalence of PROM was found to be 13.8%. The significant independent predictors associated with lower odds of PROM were no history of urinary tract infection (UTI) in the month preceding enrollment into the study (aOR=0.5, 95% CI: 0.22-0.69, p=0.038) and gestational age of 37 weeks or more (aOR=0.3, 95% CI: 0.14-0.71, p=0.01) while history of 3 or more abortions (aOR=13.1, 95% CI: 1.12-153.62, p=0.05) was associated with higher likelihood of PROM. Conclusions. Majorly urinary tract infections, low gestational age, and abortions influence premature rupture of membranes among women. There is a great need for continuous screening and prompt treatment of pregnant women for UTI especially those with history of 3 or more abortions at less than 34 weeks of gestation.

scholarly journals A Cross-Sectional Study of Obstetrical and Gynecological Parameters in Twins – A Potential Increase in Premature Rupture of Membranes and Pre-eclampsia in Twin Women

2020 ◽  
Author(s):  
Nathan Keller ◽  
Kevin C. Kiley
Keyword(s):  
General Population ◽  
Gestational Diabetes ◽  
Gynecological Cancer ◽  
Geographical Area ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Age Of Menarche

Abstract Background This cross-sectional study of 192 twins across a wide geographical area compared obstetrical and gynecological parameters between twins and the general population. Methods The study is a cross-sectional study. Gynecological variables included age of menarche, abnormal pap smears, birth control usage, endometriosis, fibroids, infertility, gynecological cancer, and osteoporosis. Obstetrical variables studied included pregnancy, ectopic pregnancies, hypertension, pre-eclampsia, gestational diabetes, and premature rupture of membranes (PROM). Chi Square and Fisher’s Exact tests were utilized to compare these binary variables between identical and fraternal twins. Finally, odds ratios were used to compare the rates of PROM, pre-eclampsia, hypertension, ectopic pregnancy, and gestational diabetes among twins compared to the general population using reputable literature sources. Results Identical twins reported the same age of menarche more frequently than their fraternal counterparts (p = 0.0021) with an odds ratio of 4.56 (95% CI = 1.62,12.83). There was also an increase in the odds of PROM 1.37 to 5.42 (95% CI = 0.95,1.96 and 4.21,6.98) and pre-eclampsia 1.17 to 3.16 (95% CI = 0.66,2.09 and 2.16,4.62) in our twin sample verse the general population. Finally, only 9.9% (18/184) reported knowledge of amnionicity and chorionicity. Conclusions Our findings suggest that further large scale research concerning PROM and pre-eclampsia in twin women may be warranted.

scholarly journals Vaginal flora in preterm premature rupture of membranes and their sensitivity to commonly used antibiotics

2014 ◽  
Vol 5 (4) ◽  
pp. 58-60 ◽  
Author(s):  
Shikha Rani ◽  
Reeti Mehra ◽  
Varsha Gupta ◽  
Anju Huria ◽  
Jagdish Chander
Keyword(s):  
Pregnant Women ◽  
Cross Sectional Study ◽  
Vaginal Flora ◽  
Gram Negative Bacteria ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Gram Negative ◽  
Preterm Premature Rupture ◽  
Ascending Infection

Background: Ascending infection is one of the most common etiologies in preterm premature rupture of membranes (PPROM). Antibiotics are used in PPROM to prolong the pregnancy and to prevent infection. But to prevent drug overuse and resistance, microorganism directed antibiotics should be used. So, this study was planned to evaluate vaginal flora in pregnant women with PPROM and their sensitivity to commonly used antibiotics. Methods: In this prospective cross-sectional study, 50 pregnant women (cases) preterm premature rupture of membranes and 28 pregnant women (controls) without complication were assessed for the type of vaginal flora and its sensitivity to commonly used antibiotics. Results: Among cases 18 (36%) women showed bacteria on Gram’s staining of vaginal swabs with Gram?negative bacteria (10/18) being the most common. Among controls, 16 (57%) women showed bacteria on Gram’s staining with Gram?positive bacteria being most common. Among cases Escherichia coli and Staphylococcus aureus were the commonest isolates. Of 8 (16%) positive bacterial cultures in cases, 6 (10%) were sensitive to Gentamicin and 2 (4%) to Ampicillin. Conclusion: Lower genital tract flora of pregnant women with PPROM predominantly consists of Gram?negative bacteria, which are sensitive to Gentamicin. DOI: http://dx.doi.org/10.3126/ajms.v5i4.9889 Asian Journal of Medical Sciences 2014 Vol.5(4); 58-60

scholarly journals The Protect Role of Serum Uric Acid to Premature Rupture of Membranes in Gestational Diabetes: a Cross-sectional Study

2020 ◽  
Author(s):  
Meixiang Guo ◽  
Jun Lu ◽  
Xiaowen Hu ◽  
Wenjing Hou ◽  
Xuemei Yu ◽  
...  
Keyword(s):  
Uric Acid ◽  
Weight Gain ◽  
Pregnant Women ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Weight Gain During Pregnancy

Abstract Background: Uric acid has strong antioxidant activity whereas its oxidative damage is closely related to many diseases. We assessed the association between serum uric acid (SUA) levels and premature rupture of membranes (PROM) in pregnant women with Gestational diabetes (GDM) in china. Method: In this cross-sectional study, a total of 456 pregnant women were enrolled. Anthropometric parameters for pregnant women were collected within 12 weeks of gestation. Weight gain during pregnancy was obtained from patients’ record. GDM was diagnosed according to 75-g oral glucose tolerance tests at 24-28th week’s gestation, and SUA was determined simultaneously. PROM was identified as the natural rupture of fetal membranes before the first stage of labor. Logistic models were fitted to identify the presence of PROM using clinical characteristics with (Model 1) or without serum uric acid (Model 2).Results: There exist differences in BMI, haemoglobin A1c, fasting blood glucose, 1-hour postprandial glucose, 2h PG, insulin levels, weight gain during pregnancy, the rate of macrosomia, PROM between women with and without GDM (all P<0.05). Furthermore, individuals with PROM had lower level of SUA than those without PROM in GDM women (P=0.030). The odds ratio of PROM decreases with the increase of SUA level. The area under the receiver operating characteristic curves for PROM based on Model 1 was larger than that in Model 2 (0.86 versus 0.71, p<0.05).Conclusion: Elevated relatively SUA levels at the 24-28th weeks of gestation were associated with a lower risk of PROM in women with GDM. SUA may be a protective factor for PROM in GDM patient. The optimal concentration of uric acid in different diseases and different populations needs to be further studied.

scholarly journals The Role of Tumor Necrosis Factor  (TNF ) and Matrix Metalloproteinase9 (MMP9) Serum in Preterm Premature Rupture of Membranes

2017 ◽  
pp. 199
Author(s):  
Ardiles Ardiles ◽  
Desmiwarti Desmiwarti ◽  
Hafni Bachtiar
Keyword(s):  
Serum Levels ◽  
Cross Sectional Study ◽  
P Value ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Preterm Premature Rupture ◽  
The Mean ◽  
Necrosis Factor

Objective: To investigate the role of TNF- and MMP-9 serum in preterm premature rupture of membranes (PPROM). Methods: We used cross-sectional study design. Subjects were all pregnant women with and without PPROM who underwent checkup at Obstetrics and Gynecology Functional Medical Staff General Hospital Dr. M. Djamil and networking hospital. Results: A total of 48 subjects were enrolled in this study. The mean serum levels of TNF- in patients with PPROM 17.43 ng/ml  12.4 ng/ml and without PPROM 8.45 ng/ml  6.86 ng/ml. The mean serum levels of MMP-9 in patients with PPROM 8.77 ng/ml  4.41 ng/ml, and without PPROM 4.46 ng/ml  3.04 ng/ml. Statistical test result p value <0.05, it can be conclude there are differences in the levels of TNF- and MMP-9 serum in premature rupture of membranes and without premature rupture of membranes pregnancy of preterm. Conclusion: There are differences in the levels of TNF- and MMP-9 serum in PPROM and without PPROM.Keywords: MMP-9, premature rupture of membranes, TNF-

PRRSV: Risikofaktoren und Herdenprävalenz in Deutschland

2019 ◽  
Vol 47 (02) ◽  
pp. 132-132
Author(s):  
Sebastian Ganz
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Respiratory Syndrome Virus ◽  
Sectional Study ◽  
Cross Sectional ◽  
Klinische Symptome

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.

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