scholarly journals Factores de riesgo asociados al parto pre término en el hospital nacional Guillermo Almenara Irigoyen de enero a junio del 2010.

2019 ◽  
pp. 143-149
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Multiple Pregnancy ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
National Hospital ◽  
Factors Associated ◽  
Factores De Riesgo

Factores de riesgo asociados al parto pre término en el hospital nacional Guillermo Almenara Irigoyen de enero a junio del 2010. Risk factors associated with preterm delivery in the Guillermo Almenara Irigoyen National Hospital from January to June 2010 Lizbeth Estefanía Díaz Polo Universidad de San Martin de Porres. Lima 12 DOI: https://doi.org/10.33017/RevECIPeru2011.0036/ RESUMEN El parto pre término ocurre entre las 22 y antes de las 37 semanas. Su etiología es multifactorial y es causa principal de morbilidad y mortalidad perinatal. El objetivo fue determinar los factores de riesgo asociados al parto pre término en gestantes del Hospital Nacional Guillermo Almenara Irigoyen de Enero a Junio del 2010. Se realizó un estudio retrospectivo, caso - control y descriptivo. Las historias clínicas de pacientes casos y controles, fueron revisadas y registradas en fichas y se procesaron con el SPSS versión 15. Los resultados fueron 81 pacientes con diagnóstico de parto pre término, con significancia estadística en las siguientes variables: ausencia de atención prenatal (OR 3.07, P>0.05), pre eclampsia (OR 20.86, P>0.001), ruptura prematura de membranas (OR 4.03, P>0.005), embarazo múltiple (OR 5.64, P>0.01), corioamnionitis (OR 2.02, P>0.1), lugar de nacimiento: sierra (OR 3.88, P>0.05) y nivel socioeconómico D-E (OR12.73, P>0.05). Se evidencio que gestantes más pobres y con menor nivel educativo presentan mayor incidencia de parto pre término [1] [2] [3]. Que el 21% de los partos pre término, estuvo asociado a la ruptura prematura de membranas (OR 4.03) dato que se encuentra dentro del rango de incidencia, ya que Aagaard-Tillery [4] (2005) señala una incidencia de la ruptura prematura de membrana pre término entre 30 y 40% y Fabián (2008) observó 11.67% de ruptura prematura de membranas [5]. Las gestantes con pre eclampsia tuvieron un riesgo 20 veces más de presentar parto pre término. El 34.6% con parto pre término presentó pre eclampsia, de ellas el 42.8% fue pre eclampsia severa, 25% leve y 32.14% síndrome de HELLP; dato similar al observado por Salviz en su estudio en el Hospital Cayetano Heredia, donde encontró un 30 % de parto pre término en pacientes con pre eclampsia; si bien es conocido que la pre eclampsia afecta del 3 al 5% de las gestaciones, no existen estudios sobre la incidencia de la pre eclampsia en el parto pre término [6]. Se concluye que el principal factor de riesgo asociado al parto pre término fue la pre eclampsia. Haber nacido en la sierra, pertenecer a nivel socioeconómico D-E, ausencia de atención prenatal, ruptura prematura de membranas, coriomanionitis y embarazo múltiple fueron también significativos. Descriptores: factores de riesgo, parto pre término, parto a término, pre eclampsia. ABSTRACT Preterm birth occurs between 22 and before 37 weeks. Its etiology is multifactorial and is a major cause of perinatal morbidity and mortality. The objective was to determine the risk factors associated with preterm delivery in pregnant women Guillermo Almenara Irigoyen National Hospital from January to June 2010. We performed a retrospective case - control and descriptive. The case histories of patients and controls were reviewed and recorded in chips and processed with SPSS version 15. The results were 81 patients diagnosed with preterm birth, with statistical significance in the following variables: absence of prenatal care (OR 3.07, P> 0.05), pre-eclampsia (OR 20.86, P <0.001), premature rupture of membranes (OR 4.03, P> 0,005), multiple pregnancy (OR 5.64, P> 0.01), chorioamnionitis (OR 2.02, P> 0.1), place of birth: saw (OR 3.88, P> 0.05) and socioeconomic status (OR12.73, P> 0.05). It was evident that more poor pregnant women with less education have a higher incidence of preterm delivery [1] [2] [3]. That 21% of preterm births was associated with premature rupture of membranes (OR 4.03) data that is within the range of incidence, as Aagaard-Tillery [4] (2005) noted an incidence of premature rupture preterm membrane between 30 and 40% and Fabian (2008) observed 11.67% of premature rupture of membranes [5]. Pregnant women with preeclampsia had a 20 times higher risk of preterm birth present. 34.6% presented with preterm birth pre-eclampsia, of which 42.8% was severe preeclampsia, 25% and 32.14% mild HELLP syndrome; data Salviz similar to that observed in their study in the Cayetano Heredia Hospital, where he found a 30 % of preterm birth in patients with preeclampsia, although it is known that pre-eclampsia affects 3 to 5% of pregnancies, no studies on the incidence of preeclampsia in preterm labor [6]. We conclude that the main risk factor associated with preterm delivery was preeclampsia. Being born in the mountains, belong to socioeconomic status, lack of prenatal care, premature rupture of membranes, coriomanionitis and multiple pregnancy were also significant. Keywords: risk factors, preterm delivery, term delivery, pre-eclampsia.

scholarly journals Factores de riesgo asociados a distocias del mecanismo del parto en gestantes primíparas atendidas en el Hospital Dr. Verdi Cevallos Balda

2020 ◽  
Vol 4 (2) ◽  
pp. 1
Author(s):  
Olga Katherine Veintimilla Chinga ◽  
María Alicia Fernanda Ledezma Hurtado ◽  
Dadier Marrero González ◽  
Lizeet López ◽  
Hugo Loor Lino
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Rural Areas ◽  
Overweight And Obesity ◽  
Modifiable Risk Factors ◽  
Maternal Complications ◽  
Factors Associated ◽  
Factores De Riesgo ◽  
Uterine Malformations ◽  
Delivery Mechanism

  Las distocias del mecanismo del parto en gestantes pueden generar consecuencias significativas tanto maternas como fetales y neonatales, existiendo diversos factores de riesgo asociados a dicha condición. La prevalencia de las distocias es variable para cada localidad, presentándose en el 0,3 % a de los casos. En este sentido, el objetivo de este trabajo fue determinar los principales factores de riesgo que se asocian a distocias del mecanismo del parto en gestantes primíparas atendidas en el Hospital Dr. Verdi Cevallos Balda. Se realizó un estudio descriptivo y retrospectivo, con 250 embarazadas atendidas en el periodo de enero 2018 a diciembre 2019. Las distocias de los mecanismos del parto en primíparas en el Hospital Dr. Verdi Cevallos se presentaron con más frecuencia en las edades entre los 20 y 34 años, con grado de instrucción secundaria, y de zonas rurales. Los principales factores de riesgos modificables asociados a distocias fueron los controles prenatales insuficientes, sobrepeso y obesidad de las gestantes; además de ganancia de peso inadecuada durante el embarazo, bajo peso fetal, duración prolongada de la primera fase del trabajo de parto e inducción del mismo. Los factores de riesgos no modificables identificados fueron la presentación de cara, estrechez pélvica, malformaciones uterinas, hipertensión arterial como enfermedad crónica asociada, talla materna menor a 140 cm y parto prolongado de más de 20 horas. Las complicaciones maternas tuvieron una alta incidencia y dentro de ellas, las cesáreas fueron las más frecuentes, mientras que el distress respiratorio fue la complicación neonatal más presentada.   Palabras clave: Distocia, factores de riesgo, peso elevado, malformaciones uterinas, complicaciones.   Abstract Dystocia of the delivery mechanism in pregnant women can generate significant maternal, fetal and neonatal consequences, with various risk factors associated with this condition. The prevalence of dystocia is variable for each locality, occurring in 0.3% of cases. In this sense, the objective of this study was to determine the main risk factors associated with dystocia in the delivery mechanism in primiparous pregnant women treated at the Dr. Verdi Cevallos Balda Hospital. A descriptive and retrospective study was carried out, with 250 pregnant women seen in the period from January 2018 to December 2019. Dystocia of the labor mechanisms in primiparous women at the Dr. Verdi Cevallos Hospital occurred more frequently in the ages between 20 and 34 years old, with a secondary education degree, and from rural areas. The main modifiable risk factors associated with dystocia were insufficient prenatal care, overweight and obesity in pregnant women; as well as inadequate weight gain during pregnancy, low fetal weight, prolonged duration of the first phase of labor and its induction. The non-modifiable risk factors identified were face presentation, pelvic narrowing, uterine malformations, arterial hypertension as an associated chronic disease, maternal height less than 140 cm and prolonged labor of more than 20 hours. Maternal complications had a high incidence and within them, caesarean sections were the most frequent, while respiratory distress was the most common neonatal complication.   Keywords: Dystocia, risk factors, high weight, uterine malformations, complications.

scholarly journals Risk Factors for Neonatal Bronchopulmonary Dysplasia in Extremely Preterm Premature Rupture of Membranes: A Retrospective Study

2020 ◽  
Author(s):  
Eishin Nakamura ◽  
Shigetaka Matsunaga ◽  
Yoshihisa Ono ◽  
Yasushi Takai ◽  
Hiroyuki Seki
Keyword(s):  
Risk Factors ◽  
Preterm Delivery ◽  
Bronchopulmonary Dysplasia ◽  
Roc Curve ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Extremely Preterm ◽  
Gestational Week ◽  
The Mean

Abstract Background: Determination of the optimal timing for termination of pregnancy in cases of preterm premature rupture of membranes (pPROM) during the extremely preterm period is still difficult. Bronchopulmonary dysplasia (BPD) is a major disease widely taken into account when determining the prognosis of respiratory disorders in a neonate. Many aspects of this disease remain unclear. With the aim of further improving the prognosis of neonates born to mothers with pPROM, this study examined cases who were diagnosed with pPROM before 28 weeks of gestation. The study analysed risk factors for neonatal BPD. Methods: This study included 73 subjects with singleton pregnancy, diagnosed with pPROM during the gestational period from 22 weeks and 0 days to 27 weeks and 6 days. The following factors were retrospectively examined: the gestational week at which pPROM was diagnosed, the gestational week at which delivery occurred, the period for which the volume of amniotic fluid was maintained, and neonatal BPD as a complication. Receiver operating characteristic (ROC) curve analyses were conducted to analyse the relationship of the onset of BPD with the duration of oligohydramnios and the gestational weeks of delivery. Results: The mean gestational week at which a diagnosis of amniorrhexis was made was 24.5±1.9 weeks (mean±SD), and that at which delivery occurred was 27.0±3.0 weeks. Fifty-seven cases (78.1%) were diagnosed with oligohydramnios, the mean duration of which was 17.4±20.5 days. The mean birth weight of neonates was 1000±455 g, of which 49 (67.1%) were diagnosed with BPD following birth. No neonates died in this study. The ROC curve indicated that the cut-off values for the duration of oligohydramnios and gestational age at delivery were 4 days and 24.1 weeks, respectively. Multivariate analysis indicated that the duration of oligohydramnios for more than 4 days before delivery and preterm delivery at less than 24.1 weeks were risk factors for the onset of BPD. Conclusion: Our findings suggest that duration of oligohydramnios for more than 4 days before delivery and preterm delivery less than 24.1 weeks are risk factors for BPD in cases who are diagnosed with pPROM before 28 weeks of gestation.

scholarly journals Risk factors for surgical site infections after caesarean section at Yaounde, Cameroon

2021 ◽  
Vol 10 (11) ◽  
pp. 4048
Author(s):  
Pierre M. Tebeu ◽  
Aurelien Kamdem ◽  
Jean P. Ngou-Mve-Ngou ◽  
Esther Meka ◽  
Jesse S. S. Antaon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Caesarean Section ◽  
Surgical Site Infections ◽  
Biomedical Sciences ◽  
Midline Incision ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Factors Associated ◽  
Chi Squared

Background: Surgical site infection is the invasion by microorganisms of the tissue layers affected by the surgical procedure. Maternal morbidity from infections has been shown to be higher after caesarean section compared to the vaginal delivery. Objective of the research was to analyze the risk factors associated with surgical site infections after caesarean section.Methods: This was a cross sectional (affected/non affected) study approved by the institutional committee for ethics and research of the faculty of medicine and biomedical sciences. A total of 310 medical files were assessed, 62 files from patients with surgical site infections and 248 files from patients without any complications. The data was collected using a pretested questionnaire and analyzed using the statistical package for the social sciences (SPSS) software version 22.0. The Chi squared and the Fisher exact tests were used to assess homogeneity between the 2 groups. Odd ratio 95% confidence interval was used to assess the association between the variables.Results: The proportion of surgical site infections during the study was 1.81%. Factors associated with surgical site infections were premature rupture of membranes (OR: 2.065; 95% CI 1.051-4.05; p=0.035); the vertical midline incision (OR=5.26; 95% CI; 1.41-19.57; p=0.013) and a operation by a resident physician doctor (OR=1.98; 95% CI 1.09-3.59; p=0.02).Conclusions: A factors associated with surgical site infections after caesarean section are a premature rupture of membranes, vertical midline incision and the qualification of the practitioner.

The Association between Shirodkar Cerclage and Preterm Premature Rupture of Membranes in Singleton Pregnancies

2020 ◽  
Author(s):  
Alberto Muniz Rodriguez ◽  
Andrew Pastor ◽  
Nathan S. Fox
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Control Group ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Increased Risk ◽  
Uterine Anomalies ◽  
Underlying Risk ◽  
Singleton Pregnancies

Objective The aim of this study was to estimate if preterm premature rupture of membranes in women with cerclage is due to the cerclage itself or rather the underlying risk factors for preterm birth in this population. Study Design This was a retrospective cohort study of singleton pregnancies who underwent Shirodkar cerclage by a single maternal–fetal medicine practice between 2005 and 2019. The control group was an equal number of randomly selected women with a singleton gestation who had a prior preterm birth and were treated with 17-OH-progesterone but no cerclage. Patients with major uterine anomalies or fetal anomalies were excluded. The primary outcome was preterm premature rupture of membranes prior to 34 weeks. Chi-square and logistic regression were used. Results A total of 350 women with cerclage (154 [44%] history-indicated, 137 [39%] ultrasound-indicated, and 59 [17%] exam-indicated) and 350 controls were included. Preterm premature rupture of membranes prior to 34 weeks did not differ between the groups (8.9% in cerclage vs. 6.0% in controls, p = 0.149, adjusted odds ratio 0.62, 95% confidence interval: 0.24–1.64) nor between the different cerclage indications (9.1% of history-indicated, 7.3% of ultrasound-indicated, and 11.9% of exam-indicated, p = 0.582). This study had 80% power with an α error of 0.05 to detect an increase in preterm premature rupture of membranes prior to 34 weeks from 6.0% in the control group to 12.0% in the cerclage group. Conclusion Cerclage does not increase the risk of preterm premature rupture of membranes prior to 34 weeks compared with other women at increased risk of preterm birth. The observed association between cerclage and preterm premature rupture of membranes is likely due to underlying risk factors and not the cerclage itself. The risk of preterm premature rupture of membranes prior to 34 weeks in women with cerclage is 10% or less and does not appear to differ based on cerclage indication. Key Points

scholarly journals Burden and risk factors of preterm birth in Nasarawa State, North Central, Nigeria: A five-year case review

2021 ◽  
Vol 7 (2) ◽  
pp. 36-41
Author(s):  
Ikrama Hassan ◽  
◽  
Surajudeen Bello ◽  
Michael Anazodo ◽  
Abdulmumuni Ahmed Lawal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Preterm Delivery ◽  
Placenta Previa ◽  
Preterm Births ◽  
Cross Sectional Study ◽  
Multiple Gestation ◽  
Case Review ◽  
Premature Rupture ◽  
Cross Sectional

Background: Preterm birth has been on the increase globally and accounting for morbidities and mortalities. Preterm delivery referred to the birth of a newborn prior to thirty seven completed gestational weeks. There is dearth of knowledge on the burden of preterm birth in this state. This study therefore determined the burden of preterm deliveries in Nasarawa State, evaluate the risk factors and identify the outcome of such deliveries. Methods: A descriptive cross-sectional study of all preterm delivered from the 1st of January 2014 to the 31st of December 2013 at the Dalhatu Araf Specialist Hospital (DASH) Lafia, General Hospital Akwanga and Medical Centre Mararaba Gurku in the Southern, Northern and Western senatorial zones of Nasarawa State respectively. Data was analyzed using SPSS version 20. Results: The mean age of mothers of preterm in this study is 26.5±5.7 years. More than three-quarter of preterm birth in Nasarawa State were at the DASH Lafia. The prevalence of preterm birth and admissions were 1.5% and 10.8% respectively. One in four of the preterm were either late preterm or extreme preterm. Singleton gestation accounted for 82.1% of the preterm births while 75.6% of such deliveries where through the vaginal mode of deliveries. Risk factors for preterm deliveries were multiple gestation, antepartum haemorrhage (placenta previa), premature rupture of membrane and previous preterm delivery. Deaths among the preterm was 11% in this study. Conclusion: The burden of preterm births in this study is comparable to other centre in same region. Half of the preterm were either late or extreme preterm. Risk factors for preterm deliveries were placenta previa, premature rupture of membrane, multiple gestation and previous preterm child birth. Death was recorded in one out of every nine preterm

scholarly journals Etiological factors of preterm delivery

2013 ◽  
Vol 3 (2) ◽  
pp. 159-163
Author(s):  
Elvira Brkičević ◽  
Gordana Grgić ◽  
Dženita Ljuca ◽  
Edin Ostrvica ◽  
Azur Tulumović
Keyword(s):  
Preterm Birth ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Multiple Pregnancy ◽  
Neonatal Morbidity ◽  
Etiological Factor ◽  
Premature Delivery ◽  
Control Group ◽  
Etiological Factors ◽  
Experimental Group

Introduction: Preterm delivery is the delivery before 37 weeks of gestation are completed. Preterm birth is a major course of neonatal morbidity and mortality, the incidence of premature delivery in developedcountries is 5 to 9%. Aims of this study were to determine the common etiological factors for preterm delivery, most common weeks of gestation for pretern delivery, and most commom way of delivery for preterm delivery.Methods: The study included 600 patients divided into two groups, experimental group (included 300 preterm delivered pregnant women), control group (included 300 term delivered women).Results: The incidence of preterm delivery in pregnant women younger than 18 years was 4.4%, and in pregnant women older than 35 years was 14%. 44.6 % of preterm delivered women at the experimentalgroup had lower education. In the experimental group burdened obstetrical history had 29%, 17.2% had a preterm delivery, 35.6% had a premature rupture of membranes, 15% had a preterm delivery before32 weeks of gestation, 12.4% between 32-33.6 weeks of gestation, while 72.6% of deliveries were between 34- 36.6 weeks of gestation. Multiple pregnancy as an etiological factor was present in 10.07% ofcases. Extragenital diseases were present in 10.4%. In the experimental group there were 29%, while in the control group there were 15% subjects with burdened obstetrical history.Conclusions: Preterm birth more often occurs in a pregnant women younger than 18 and older than 35 years, and in a pregnant women of lower educational degree. Preterm delivery in the most commoncases was fi nished in period from 34 to 36.6 weeks of gestation. The most common etiological factor of preterm delivery in the experimental group was preterm rupture of membranes and idiopathic pretermdelivery.

scholarly journals Analysis of Pregnancy Characteristics and Perinatal Outcome of Mediastinal Uterus in China

2021 ◽  
Author(s):  
Na Zhang ◽  
Ying Wang ◽  
Li Zhang ◽  
Chanyun Xiao
Keyword(s):  
Preterm Birth ◽  
Pregnant Women ◽  
Postpartum Hemorrhage ◽  
Mode Of Delivery ◽  
Premature Delivery ◽  
Targeted Prevention ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Neonatal Asphyxia ◽  
Fetal Position

Background: To analyze the complications and outcome of mediastinal uterine pregnancy, and put forward targeted prevention and treatment measures. Methods: A total of 248 pregnant women with mediastinal uterus treated were enrolled from Jan 2015 to Dec 2018 in the Maternal and Child Health Hospital of Hubei Province, China. The data, including complications of pregnancy, gestational weeks, mode of delivery, postpartum hemorrhage, placental condition and perinatal prognosis, were collected and analyzed. Results: There were 12 cases with abnormal fetal position in the previous cesarean section. The total number of cases with abnormal fetal position was 99(49.75%). For women with abnormal fetal position during mediastinal uterine pregnancy, there was a significant increase in the incidence of placental abruption (P<0.05). The average gestational age at termination of pregnancy was 37+5weeks. There were 55 cases (22.18%) of premature and 49 cases (19.75%) of premature rupture of membranes, including 29 cases of abnormal fetal position and premature rupture of membranes, mediastinal uterus preterm birth, premature rupture of membranes (P<0.05). There were 13 cases (5.24%) of postpartum hemorrhage, natural birth without neonatal asphyxia, five cases (2.02%) of neonatal asphyxia, preterm birth, and 51 cases (20.56%) of placental adhesion. Of these, 37 cases were cesarean, 13 were spontaneous production, and 71 were fetal umbilical cord winding. Conclusion: The pregnancy induced spontaneous abortion, premature delivery, premature rupture of membranes and abnormal fetal position in mediastinal uterus are significantly higher than normal pregnancy. The complications during delivery are significantly higher than in normal pregnant women.

scholarly journals Prevalence, antimicrobial susceptibility patterns, serotypes and risk factors for group B streptococcus rectovaginal isolates among pregnant women at Kenyatta National Hospital, Kenya; A cross-sectional study

2019 ◽  
Author(s):  
Jisuvei Clayton Salano ◽  
Osoti Alfred ◽  
Maina Anne Njeri
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Group B Streptococcus ◽  
Penicillin G ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Group B ◽  
Susceptibility Patterns

Abstract Background: Estimates of group B streptococcus (GBS) disease burden, antimicrobial susceptibility, and serotypes in pregnant women are limited for many resource-limited countries including Kenya. These data are required to inform recommendations for prophylaxis and treatment of infections due to GBS. Methods: We evaluated the prevalence, antimicrobial susceptibility patterns, serotypes, and risk factors associated with rectovaginal GBS colonization among pregnant women receiving antenatal care at Kenyatta National Hospital (KNH) between August and November 2017. Consenting pregnant women between 12 and 40 weeks of gestation were enrolled. Interview-administered questionnaires were used to assess risk factors associated with GBS colonization. An anorectal swab and a lower vaginal swab were collected and cultured on Granada agar for GBS isolation. Positive colonies were tested for antimicrobial susceptibility to penicillin G, ampicillin, vancomycin, and clindamycin using the disk diffusion method. Serotyping was performed by latex agglutination. Logistic regression was used to identify factors associated with GBS colonization. Results: A total of 292 women were enrolled. Median age was 30 years (Interquatile range {IQR} 26-35) with a median gestational age of 35 weeks (IQR 30-37). Overall GBS was identified in 60/292 (20.5%) of participants. Among the positive isolates, resistance was detected for penicillin G in 42/60 (72.4%) isolates, ampicillin in 32/60 (55.2%) isolates, clindamycin in 14/60 (30.4%) isolates, and vancomycin in 14 (24.1%) isolates. All ten GBS serotypes were isolated, and 37/53 (69.8%) of GBS positive participants were colonized by more than one serotype. None of the risk factors was associated with GBS colonization.Conclusion: The prevalence of GBS colonization was high among mothers attending antenatal clinic at KNH. In addition, a high proportion of GBS isolates were resistant to commonly prescribed intrapartum antibiotics. Hence, other measures like GBS vaccination is a potentially useful approaches to GBS prevention and control in this population. Screening of pregnant mothers for GBS colonization should be introduced and antimicrobial susceptibility test performed on GBS positive samples to guide antibiotic prophylaxis.

scholarly journals High-density cervical ureaplasma urealyticum colonization in pregnant women

2006 ◽  
Vol 63 (8) ◽  
pp. 737-741 ◽  
Author(s):  
Gordana Randjelovic ◽  
Branislava Kocic ◽  
Biljana Miljkovic-Selimovic ◽  
Snezana Mladenovic-Antic ◽  
Predrag Stojanovic ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Preterm Delivery ◽  
Ureaplasma Urealyticum ◽  
High Density ◽  
Control Group ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Risk Pregnancy ◽  
Normal Term ◽  
Term Delivery

Background/aim: Ureaplasma urealyticum, a common commensal of the female lower genital tract, has been observed as an important opportunistic pathogen during pregnancy. The aims of this study were to determine the degree of cervical colonization with U. urealyticum in pregnant women with risk pregnancy and in pregnant women with normal term delivery and to evaluate the correlation between high-density cervical U. urealyticum colonization and premature rupture of membranes (PROM) as well. Methods. This research was conducted on the samples comprising 130 hospitalized pregnant women with threatening preterm delivery and premature rupture of membranes. The control group consisted of 39 pregnant women with term delivery without PROM. In addition to standard bacteriological examination and performing direct immunofluorescence test to detect Chlamydia trachomatis, cervical swabs were also examined for the presence of U. urealyticum and Mycoplasma hominis by commercially available Mycofast Evolution 2 test (International Microbio, France). Results. The number of findings with isolated high-density U. urealyticum in the target group was 69 (53.08%), while in the control group was 14 (35.90%). Premature rupture of membranes (PROM) occurred in 43 (33.08%) examinees: 29 were pPROM, and 14 were PROM. The finding of U.urealyticum ?104 was determined in 25 (58.14%) pregnant women with rupture, 17 were pPROM, and 8 were PROM. There was statistically significant difference in the finding of high-density U. urealyticum between the pregnant women with PROM and the control group (?? = 4.06, p < 0.05). U. urealyticum was predominant bacterial species found in 62.79% of isolates in the PROM cases, while in 32.56% it was isolated alone. Among the 49 pregnant women with preterm delivery, pPROM occurred in 29 (59.18%) examinees, and in 70.83% of pregnant women with findings of high-density U. urealyticum pPROM was observed. Conclusion. Cervical colonization with U. urealyticum ? 104 is more frequent in pregnant women with risk pregnancy than in pregnant women with normal term delivery. High-density cervical U. urealyticum colonization should be observed as a possible etiological factor for PROM.

scholarly journals Risk Factors and Outcomes of Preterm Premature Rupture of Membranes in a Cohort of 6968 Pregnant Women Prospectively Recruited

2019 ◽  
Vol 8 (11) ◽  
pp. 1987 ◽  
Author(s):  
Damien Bouvier ◽  
Jean-Claude Forest ◽  
Loïc Blanchon ◽  
Emmanuel Bujold ◽  
Bruno Pereira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Preterm Labor ◽  
Regression Analyses ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Level Of Education ◽  
Preterm Premature Rupture ◽  
History Of

We revisited risk factors and outcomes related to the preterm premature rupture of membranes (PPROM). A total of 7866 pregnant women were recruited during 5 years at their first prenatal visit to the perinatal clinic of the institution. We compared three groups (women without prematurity, women with spontaneous preterm labor with intact membranes (sPL with IM), women with PPROM) regarding 60 criteria about characteristics, lifestyle, medical, gynecological, obstetrical history of mothers, medication during pregnancy, events at delivery, and complications in neonates. Logistic regression analyses adjusting for potential confounding factors were used. Of the 6968 women selected, 189 (2.8%) presented a PPROM, and 225 (3.2%) an sPL with IM. The specific risk factors for PPROM were body mass index (BMI) <18.5 kg/m2 (adjusted odds ratio, aOR: 2.00 (1.09–3.67)), history of PPROM (aOR: 2.75 (1.19–6.36)), nulliparity (aOR: 2.52 (1.77–3.60)), gestational diabetes (aOR: 1.87 (1.16–2.99)), and low level of education (aOR: 2.39 (1.20–4.78)). The complications associated with PPROM were abruption placentae, cesarean, APGAR 5′ <4, birth weight <2500 g, stillbirth, neonatal jaundice, and hospitalization of mother and neonates. All these complications were also associated with sPL with IM. Our study confirms some of the risk factors of PPROM and highlights a new one: gestational diabetes. Outcomes of PPROM are related to prematurity.

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