scholarly journals Ischemic stroke following Dengue fever: A case report

2015 ◽  
Vol 7 (2) ◽  
pp. 107-108 ◽  
Author(s):  
Robin George Manappallil

Dengue fever is an acute febrile illness associated with severe headache, myalgias, arthralgias, rashes, leucopenia and thrombocytopenia. Occasionally unusual haemorrhage such as gastrointestinal bleeding, intracranial haemorrhage, hypermenorrhoea, hematuria and massive epistaxis occur. This is a case of an elderly male with dengue fever who presented with ischemic stroke.  Asian Journal of Medical Sciences Vol.7(2) 2015 107-108

2019 ◽  
Vol 10 (2) ◽  
pp. 62-64
Author(s):  
Robin George Manappallil ◽  
Pradeep Kumar V.G. ◽  
Apurva Rao K.S.

Dengue fever is an acute febrile viral illness characterized by severe headache, myalgia, arthralgia, rashes, leucopenia and thrombocytopenia. Patients may face haemorrhagic complications like gastrointestinal bleeding, intracranial haemorrhage, menorrhagia, hematomas, hematuria and massive epistaxis. Ischemic stroke in dengue fever is a rare scenario; and Parkinsonism following basal ganglia infarction in dengue fever, to the best of our knowledge, has not been reported yet.


2020 ◽  
Vol 40 (2) ◽  
pp. 93-99
Author(s):  
Saheli Misra Chatterjee ◽  
Suman Mondal ◽  
Kaushik Mukhopadhyay ◽  
Niloy Kumar Das

Introduction: The disease spectrum of dengue, scrub typhus and typhoid presenting as acute febrile illness is often a diagnostic dilemma to the clinician. The purpose of this study is to compare the clinical features and laboratory parameters of children suffering from typhoid, dengue and scrub typhus and use these parameters in early identification of scrub typhus before conclusion is made from serological diagnosis. Methods: A retrospective observational analytical study was conducted among children presenting with acute febrile illness in a tertiary care level hospital. Over the period of one year 113 cases were identified of which 39 were dengue, 44 were typhoid and 30 were scrub typhus. Results: The mean age of the children was 7.45 ± 2.98 years, median was eight with an interquartile range of six to ten years. The male to female ratio was 1.3:1. Symptoms of vomiting (61.54%), headache (46.15%) and hepatomegaly (47.37%) were significantly higher among children with dengue fever. A significantly higher number of children with scrub typhus fever had temperature above 40°C. The incidence of low haemoglobin, raised C reactive protein, raised ALT and low albumin levels were significantly higher in them. Children with acute febrile illness having temperature > 40°C, absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to suffer from scrub typhus with relative probability ratio (RPR) of 25.68 and 10.57 respectively (p < 0.001). Children with WBC < 5000/mm3 were more likely to be suffering from dengue with RPR of 10.60 (p < 0.001). Conclusion: Children with acute febrile illness with temperature > 40°C and absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to be suffering from scrub typhus.


2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Surendra Sapkota ◽  
Sudeep Bhandari ◽  
Subash Sapkota ◽  
Rabin Hamal

Dengue fever and scrub typhus are common causes of acute febrile illness of unclear origin in Asia. Though coinfections of many vector-borne diseases have been described, articles on dengue and scrub typhus coinfection are distinctly limited. In case of coinfection with dengue and scrub typhus, vigilant monitoring of vitals, platelets transfusion, and timely treatment with doxycycline are necessary. High degree of suspicion has to be made for coinfection in a patient presenting with febrile illness with thrombocytopenia and deranged laboratory parameters in postmonsoon season in endemic regions in Asia.


2019 ◽  
Vol 7 (1) ◽  
pp. 1-5
Author(s):  
Saravanan Thangavelu ◽  
Clement Jenil Dhas ◽  
Mohammad Zeya Ansari

Dengue fever, which is transmitted by the mosquito Aedes aegypti is a common acute viral febrile illness, affecting 390 million people worldwide every year. It is endemic in several countries. Although the usual presentation is that of a self-limiting illness, its complications are protean. Infection Associated with Hemophagocytic Syndrome (IAHS) is a rare and fatal complication of dengue fever. It should be suspected in a patient with fever beyond seven days, associated with hepatosplenomegaly, hyperferritinemia, worsening cytopenias and development of multiorgan dysfunction(MOD). We report a 19-year-old female, who presented with an acute febrile illness and was diagnosed with primary dengue fever. Despite appropriate supportive therapy, she worsened clinically during the course of hospitalisation. A disproportionately high ferritin level and persistent bicytopenia prompted investigations for hemophagocytic lymphohistiocytosis (HLH). Further evaluation revealed features of HLH, as per the diagnostic criteria laid down by the Histiocyte Society. She was successfully treated with glucocorticoids, etoposide and intravenous immunoglobin and other supportive therapy. She had severe cytopenia and cardiac dysfunction during the course of her illness and its management. This case adds to the limited adult cases of dengue-associated hemophagocytic syndrome and shows its difficulty in management due to associated extra complications.


Author(s):  
Swati Gupta ◽  
Sachee Agrawal ◽  
Jayanthi Shastri

Introduction: Dengue and Chikungunya fever are arboviral diseases which are spread by a common vector. Being clinically indistinguishable, it is necessary to distinguish both either by molecular or serology testing. Aim: To estimate the seroprevalence of Dengue and Chikungunya mono-infection as well as dual infection in patients with acute febrile illness. Materials and Methods: Two hundred patients with acute febrile illness were enrolled from April 2015 to October 2016. Detailed clinical history was documented. Samples were collected and subjected to Polymerase Chain Reaction (PCR) and Enzyme Linked Immuno Sorbent Assay (ELISA) testing. For qualitative data, frequency percentage table was used and association was done using Chi-square test. Results: Out of 200 patients, 8.5% had Chikungunya mono-infection and 41.5% patients had Dengue mono-infection. Dengue and Chikungunya co-infection was found in 4.5% patients. Most affected age group was 18-60 years wherein male preponderance was seen. In Chikungunya fever, 82.4% had morning stiffness and 35.3% had joint swelling; elbow and knee were the most commonly affected joints. In Chikungunya fever, 76.5% patients had restricted joint movements and 52.9% had Visual Analog Score (VAS) of 6-10. In Dengue fever, myalgia (67.5%) and rash (20.5%) were common symptoms. A total of 61.4% patients of Dengue fever had low platelet count. All Chikungunya cases and 88.1% Dengue cases detected by PCR had fever duration of less than five days. 85% of Chikungunya and 69% of Dengue cases detected by IgM ELISA had fever duration of more than five days. Conclusion: Diagnostic algorithms of acute febrile illness cases should include testing by both molecular and serology for both the viruses, which is the absolute need of the hour.


2017 ◽  
Vol 15 (2) ◽  
pp. 61-64
Author(s):  
Jinnat Fatema Saira Safa ◽  
Farhana Mahmood ◽  
Sheikh Md Hasan Mamun ◽  
Mohammad Ferdous ◽  
Mohammad Jalaluddin

Leptospirosis, a zoonotic disease is increasingly being recognized in developing countries. It is often underdiagnosed resulting in significant mortality as the presenting features mimic other commonly prevailing diseases like Malaria, Dengue, Acute hepatitis, Typhoid in developing world. We report a case of 32 yrs old male, sewer worker presented with acute febrile illness with icterus, hemorrhagic manifestation and pulmonary-renal involvement, diagnosed as Severe Leptospirosis (Weil’s disease) confirmed by ICT method. This experience highlights the importance of considering Leptospirosis early in the diagnosis of acute non specific febrile illness with multi-organ involvement to cutoff mortality from this fatal disease.Chatt Maa Shi Hosp Med Coll J; Vol.15 (2); Jul 2016; Page 61-64


2019 ◽  
Vol 10 (1) ◽  
pp. 96-97
Author(s):  
Md Mahmudur Rahman Siddiqui ◽  
Quazi Tarikul Islam ◽  
Mohammad Shahidul Islam

Acute febrile illness is the most common clinical presentation among patients attending to doctor in developing countries. In Bangladesh, dengue and typhoid fever have emerged as major public health problems. Co-infection with both these diseases is rarely reported and are known to present with overlapping symptoms making the clinical diagnosis difficult. The exact incidence of dengue and typhoid co-infection is not known. Here we report a case of co-infection of dengue fever with typhoid fever. Anwer Khan Modern Medical College Journal Vol. 10, No. 1: Jan 2019, P 96-97


2018 ◽  
Vol 9 (2) ◽  
pp. 43-44
Author(s):  
Robin George Manappallil ◽  
Mounika Yelisetti

Dengue fever is an acute febrile viral illness associated with severe headache, myalgia, arthralgia, rashes, leucopenia and thrombocytopenia. These patients can present with haemorrhagic manifestations. Wet purpura in oral mucosa occurs when there is a drastic fall in platelet counts; and can be taken as a sign of impending systemic haemorrhage. This is the case of a young male who was diagnosed to have Dengue fever. He developed severe thrombocytopenia and wet purpura, following which he had gastrointestinal bleed. Dengue fever presenting with wet purpura is a rare scenario.Asian Journal of Medical Sciences Vol.9(2) 2018 43-44


2019 ◽  
Vol 9 (1) ◽  
pp. 80-81
Author(s):  
Shahana Zaman ◽  
Lubna Rashid ◽  
Muhammad Abdur Rahim

Rickettsial fevers are a heterogeneous group of illness characterized by fever, headache, myalgia and rash. Rickettsia has a wide global distribution and regional species specificity. In spite of significant serosurveillance reports, rickettsial fevers are occasionally reported in Bangladesh. Here, we report a case of scrub typhus occurring in a young girl who presented with fever and had a typical eschar. We emphasize rickettsial fever should be a differential diagnosis in acute fever without localizing symptoms and signs in Bangladesh. Birdem Med J 2019; 9(1): 80-81


2019 ◽  
Vol 4 (1) ◽  
pp. 23 ◽  
Author(s):  
Yazli Yuhana ◽  
Ampai Tanganuchitcharnchai ◽  
Pimpan Sujariyakul ◽  
Piengchan Sonthayanon ◽  
Kesinee Chotivanich ◽  
...  

Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia.


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