Hymenoptera stings: a study of clinical profile, complication and outcome from a teaching hospital of central Nepal

Background Hymenoptera sting is a common health hazard in the tropics. Wasp and Bee stings can produce symptoms ranging from local allergic reactions to serious complications including anaphylaxis and multiple organ dysfunction syndromes.Objective To evaluate the clinical profile, management and early outcome of patients with gallbladder cancer.Methods We prospectively analyzed all the consecutive patients with Hymenopterid sting (Wasp and Bee stings), who were admitted in Nephrology Unit in college of Medical Sciences Teaching hospital over a period of two year; from June 2010 to May 2012. Data including demographic profile, clinical profile, complications and outcomes associated with the Hymenopterid stings were entered in a designated profroma and were analyzed.Results A total of 15 cases with Hymenopterid stings (Wasp and Bee stings) were analyzed. Majority of the cases were females (n=8). The male to female ratio was 0.88. The mean age of the case was 37.1± 17.38years. Most of the cases (n=11) were younger subjects d"45 years and majority of them felt in the age group of 21-30 years; (n=4). Mean number of stings (Wasp or Bee stings), were 46 ± 18.4 (12-74) and the mean time to reach the hospital from the bite time was 78.23±82.24 hours (30 minutes-13 days). Black Wasps were the commonest species to inflict the stings in (n=10) cases and Bees in (n=5) cases. The Hymenoptera stings were observed more frequently in the month of July to September in (n=8). The commonest site of bite was head and face seen in (n=11) cases. Among the clinical presentations the commonest clinical presentation was local burning pain and pruritus which was present in all the cases (n=15) followed by nausea (n=10). The commonest clinical sign was bipedal edema which was seen in (n=7) cases. Low Hb (defined as Hb <10gm/dl) was seen in (n=5) cases of Hymenopterid stings. Low platelet (defined as Platelet < 100X109/L) was documented in (n=10) cases. Serum creatinine >1.5mg /dl was seen in (n=7) cases. Low serum albumin (defined as Serum Albumin (<3.5gm/dl) was seen in (n=6) cases. Among the complications, the most common complication was Hepatitis which was seen in (n=9) cases, followed by Acute Kidney Injury. There was no mortality associated with Hymenopterid stings in our study. However 1 patient left against medical advice.Conclusion Black Wasps were the commonest species to inflict the stings in (n=10) cases. The most common complication of Hymenoptera sting was Hepatitis, which was seen in (n=9) of cases, followed by Acute Kidney Injury. Majority of complications were seen in Wasp stings which caused significant morbidity. No mortality was observed in our study except one case; that left hospital against medical advice. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-3, 17-24

Download Full-text

Incidence of acute kidney injury in asphyxiated babies in university of Uyo teaching hospital, Uyo, Nigeria

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20202882 ◽

2020 ◽

Vol 8 (7) ◽

pp. 2477

Author(s):

Ikpeme Enobong Emmanuel ◽

Dixonumo Ofonime Tony ◽

Udoh Mary Paulinus ◽

Udo Jacob J.

Keyword(s):

Acute Kidney Injury ◽

Serum Creatinine ◽

Teaching Hospital ◽

Birth Asphyxia ◽

Kidney Injury ◽

Neonatal Morbidity ◽

Urinary Output ◽

Cross Sectional ◽

Female Ratio ◽

The Mean

Background: Acute Kidney Injury (AKI) is a consequence of birth asphyxia. In resource poor countries like ours, birth asphyxia still contributes to the high rates of neonatal morbidity and mortality. A few studies have reported the incidence of AKI in birth asphyxia in Nigeria but none from Uyo, south-south region of Nigeria.Methods: A descriptive cross sectional study carried out in the Newborn Unit of the University of Uyo Teaching hospital, Uyo, Nigeria over a period of eight months. One hundred and four term neonates with provisional diagnosis of birth asphyxia using Apgar scoring were recruited. Blood sample was collected within six hours of life from each subject for serum creatinine estimation using modified Jaffe method. Urine output was assessed by application of plastic collection bag to the skin by adhesive patch. AKI was diagnosed when sCr >1.5mg/dl while oliguria was defined as urinary output <1.5ml/kg/hour.Results: Of the total of 104 asphyxiated neonates enrolled into the study, 56 (53.8%) were males while 48 (46.2%) were females giving a male/female ratio of 1.2:1. Twenty-eight (26.9%) of the subjects had severe birth asphyxia; 52 (50%) had moderate birth asphyxia while 24 (23.1%) were mildly asphyxiated. Incidence of AKI was 48 (46.1%), twelve (11.5%) had AKI based on serum creatinine criteria while 36 (34.6%) had AKI based on urinary output criteria. The mean urinary output (ml/kg/hr) for the subjects was 1.65±0.68 while the mean serum creatinine (mg/dl) was 0.88±0.46.Conclusions: The incidence of AKI among asphyxiated neonates in our locale is high at 46.1%.

Download Full-text

Clinical Profile and Short-Term Outcomes of Acute Kidney Injury in Patients Admitted to a Teaching Hospital in Ethiopia: A Prospective Study

International Journal of Nephrology and Renovascular Disease ◽

10.2147/ijnrd.s318037 ◽

2021 ◽

Vol Volume 14 ◽

pp. 201-209

Author(s):

Abinet Abebe ◽

Bezie Kebede ◽

Yohannes Wobie

Keyword(s):

Acute Kidney Injury ◽

Prospective Study ◽

Teaching Hospital ◽

Kidney Injury ◽

Clinical Profile ◽

Short Term ◽

A Prospective Study

Download Full-text

A prospective study of clinical profile of patients with acute kidney injury following acute gastroenteritis

Medpusle International Journal of Medicine ◽

10.26611/102116112 ◽

2020 ◽

Vol 16 (1) ◽

pp. 53-56

Author(s):

Dnyaneshwar Malharrao Ghuge ◽

Keyword(s):

Acute Kidney Injury ◽

Acute Gastroenteritis ◽

Early Recognition ◽

Kidney Injury ◽

Clinical Profile ◽

Common Symptom ◽

Age Group ◽

Female Ratio ◽

Number Of Patients ◽

Co Morbidity

Background: Increasing number of patients of AGE are now diagnosed with AKI.. Over the recent years there has been increasing recognition that relatively small rises in serum creatinine in a variety of clinical settings are associated with worse outcomes. In present study, we aimed to study clinical profile of patients with acute kidney injury following acute gastroenteritis at our tertiary hospital. Material and Methods: Present study was conducted in patients who were diagnosed to have AKI following acute gastroenteritis. Statistical analysis was done using descriptive statistics. Results were expressed as mean and standard deviation for continuous data and frequency as number and percentage. Results: After applying inclusion and exclusion criteria, total 72 patients of AGE with AKI were considered for this study. Most common age group in this study was age group of 61–70 years (28%), followed by age group of 51–60 years (25%). Mean age of study patients was 53.8 ± 11.7 years. Male patients (64%) were more than female patients (36%). Male to female ratio was 1.8:1. According to clinical presentation most common symptom was loose stools (100 %), followed by fever (76 %) and vomiting (68 %). Other complaints were shortness of breath (18 %) and altered sensorium (8 %). Diabetes was the most common co-morbidity noted (39 %) followed by hypertension (34%). AKI was staged for severity according to the KDIGO criteria. At the time of diagnosis most patients were in stage 1 (57%), while 32% and 11% were in stage 2 and 3 respectively.In this study hypotension, hyperkalemia were common complications of Acute Kidney Injury. Other complications were metabolic acidosis, encephalopathy, pulmonary edema, anemia, multi organ dysfunction syndrome (MODS), hypokalemia and hyponatremia. In present study, 11% patients underwent hemodialysis and 3 % mortality was noted. Conclusion: Acute kidney injury in patients with acute gastroenteritis had good prognosis if detected earlier. Early recognition of AKI is essential to ensure prompt and appropriate management, and to avoid progression to deadlier stages of the disease.

Download Full-text

Acute kidney injury in children: A study of etiology, clinical profile, and short-term outcomes at the University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria

Saudi Journal of Kidney Diseases and Transplantation ◽

10.4103/1319-2442.256849 ◽

2019 ◽

Vol 30 (2) ◽

pp. 421 ◽

Cited By ~ 1

Author(s):

EmmanuelA Anigilaje ◽

AdogahI Adebayo ◽

SundayA Ocheni

Keyword(s):

Acute Kidney Injury ◽

Teaching Hospital ◽

Kidney Injury ◽

Clinical Profile ◽

Short Term ◽

The University

Download Full-text

CLINICAL PROFILE AND MANAGEMENT OF PATIENTS ADMITTED WITH ACUTE KIDNEY INJURY SECONDARY TO GASTROENTERITIS IN A TERTIARY CARE TEACHING HOSPITAL

MVP Journal of Medical Sciences ◽

10.18311/mvpjms/2018/v5i2/18282 ◽

2018 ◽

Vol 5 (2) ◽

pp. 134-139

Author(s):

Umang Patil ◽

Jitendra Kodilkar ◽

Neelima Chafekar ◽

Deodatta Chafekar ◽

Gauri Anand Diwan ◽

...

Keyword(s):

Acute Kidney Injury ◽

Teaching Hospital ◽

Tertiary Care ◽

Kidney Injury ◽

Clinical Profile ◽

Tertiary Care Teaching Hospital ◽

Care Teaching

Download Full-text

Preoperative Low Serum Albumin Levels Increase the Requirement of Renal Replacement Therapy after Cardiac Surgery

The Heart Surgery Forum ◽

10.1532/hsf.1577 ◽

2016 ◽

Vol 19 (3) ◽

pp. 123 ◽

Cited By ~ 7

Author(s):

Orhan Findik ◽

Ufuk Aydin ◽

Ozgur Baris ◽

Hakan Parlar ◽

Gokcen Atilboz Alagoz ◽

...

Keyword(s):

Acute Kidney Injury ◽

Regression Analysis ◽

Cardiac Surgery ◽

Renal Replacement Therapy ◽

Serum Albumin ◽

Replacement Therapy ◽

Kidney Injury ◽

Preoperative Serum ◽

Group I ◽

Group Ii

Background: Acute kidney injury is a common complication of cardiac surgery that increases morbidity and mortality. The aim of the present study is to analyze the association of preoperative serum albumin levels with acute kidney injury and the requirement of renal replacement therapy after isolated coronary artery bypass graft surgery (CABG). Methods: We retrospectively reviewed the prospectively collected data of 530 adult patients who underwent isolated CABG surgery with normal renal function. The perioperative clinical data of the patients included demographic data, laboratory data, length of stay, in-hospital complications and mortality. The patient population was divided into two groups: group I patients with preoperative serum albumin levels <3.5 mg/dL; and group II pateints with preoperative serum albumin levels ≥3.5 mg/dL. Results: There were 413 patients in group I and 117 patients in group II. Postoperative acute kidney injury (AKI) occured in 33 patients (28.2%) in group I and in 79 patients (19.1%) in group II. Renal replacement therapy was required in 17 patients (3.2%) (8 patients from group I; 9 patients from group II; P = .018). 30-day mortality occurred in 18 patients (3.4%) (10 patients from group I; 8 patients from group II; P = .037). Fourteen of these patients required renal replacement therapy. Logistic regression analysis revealing the presence of lower serum albumin levels preoperatively was shown to be associated with increased incidence of postoperative AKI (OR: 1.661; 95% CI: 1.037-2.661; P = .035). Logistic regression analysis also revealed that DM (OR: 3.325; 95% CI: 2.162-5.114; P = .000) was another independent risk factor for AKI after isolated CABG. Conclusion: Low preoperative serum albumin levels result in severe acute kidney injury and increase the rate of renal replacement therapy and mortality after isolated CABG.

Download Full-text