scholarly journals Is Iron Deficiency Anaemia, a risk Factor For Wheeze Associated Respiratory Tract Infection in Children?

2015 ◽  
Vol 34 (3) ◽  
pp. 195-199
Author(s):  
A Agrawal ◽  
R Gupta ◽  
KD Sodhi ◽  
V Raghav

Introduction: Wheezing is the common in children with cumulative prevalence of almost 50% by the age of 6 yrs. Iron deficiency anaemia is an independent risk factor for lower respiratory tract infections (LRTI), however may also play an important role in wheeze associated respiratory tract infection. The present study aimed at finding a correlation between iron deficiency anaemia and wheeze associated respiratory tract infection. Materials and Methods: This case control study was conducted at a multidisciplinary tertiary care hospital from Jul 2012 to Jun 2013 among children six months to five years and having ≥2 episodes of wheeze associated respiratory tract infections. The clinical presentation and laboratory profile were recorded on a predesigned performa. Iron deficiency anaemia was diagnosed by haemoglobin <11.0 gm%, serum ferritin<12ng/ml and RDW>15%. The statistical analysis was done using SPSS, Version 15.0. Results: A total of 100 children were enrolled in the study, of which 50 cases and 50 matched controls. Majority of subjects in both groups were males (n=31;62%),with male to female ratio of 1.6:1. Proportion of cases with iron deficiency anaemia were higher among cases(32%) as compared to controls(24%) but the difference between two groups was not significant statistically (p=0.373) despite having higher risk(OR=1.49;95% CI=0.62-3.59). Mean monocyte, oeosinophil and absolute oeosinophil count was found to be significantly higher in cases as compared to controls (p<0.05). Conclusion: The present study do not suggest a possible linkage between iron deficiency anemia and wheeze associated respiratory infection, however its role as causative factor needs to be explored through long-term prospective and intervention studies on a large population.J Nepal Paediatr Soc 2014;34(3):195-199 DOI: http://dx.doi.org/10.3126/jnps.v34i3.11378

2018 ◽  
Vol 1 (1) ◽  
pp. 5-8
Author(s):  
Henish Shakya ◽  
Saurav Singh ◽  
Ashish Lakhey

Introduction: Lower respiratory tract infection is a major cause of death in children in a developing country and anemia is found to be one of the commonest associated cofactors. This study was aimed to determine association of anemia in children with lower respiratory tract infections.Materials and Methods: The retrospective study was done over a one-year period for children under 5 years of age, admitted in Pediatric Ward of a tertiary Hospital in Lalitpur. The study included 100 diagnosed cases of lower respiratory tract infections as per WHO criteria and 100 age and sex matched patients who did not have respiratory complaints as controls, excluding prematurity, chronic diseases, malnutrition and severe systemic illness. Appropriate clinical history, examination routine investigations like hemoglobin, peripheral smear, and Chest X-ray were included.Results: The age distribution maximum children were in the age group of 3 months to 23 months with significant association with prevalence of both pneumonia (p value 0.005) and anemia (p value 0.002). Anemia was found to be a significant risk factor for LRTI (p value < 0.001) with odds ratio of 2.68 and 95% CI (1.51 – 4.75).Conclusions: Anemia was significantly found to be associated with lower respiratory tract infections and these children were found to be 2.68 times more susceptible to lower respiratory tract infections. Early diagnosis and prevention of anemia is thus important to reduce the incidence of lower respiratory tract infections in children.Nepalese Medical Journal. vol.1, No. 1, 2018, page: 5-8


2021 ◽  
Vol 71 (4) ◽  
pp. 1322-26
Author(s):  
Raazia Nawaz ◽  
Shabbir Hussain ◽  
Arshad Khushdil ◽  
Sidra Tanveer ◽  
Maria Javed ◽  
...  

Objective: To establish association between acute lower respiratory tract infection and iron deficiency anemia. Study Design: Case-control study. Place and Duration of Study: Pediatrics Department, Pak Emirates Military Hospital, Rawalpindi, from Dec 2017 to May 2018. Methodology: A total of 100 children with age ranging from 6-60 months were selected for this study with 50 being in each group. Study group constituted of children presenting with acute lower respiratory tract infection and healthy children presenting to outpatient were taken as controls. Hemoglobin levels (<11g/dl), mean corpuscular volume (<70fl), Serum Ferritin (<30ng/ml) and red blood cell Morphology were used to determine iron deficiency anemia. Patients meeting the WHO criteria were labeled to have acute lower respiratory tract infection. Results: The frequency of iron deficiency was found to be 40 (80%) in cases and only 34 (17%) in healthy controls. A significant association was found between iron deficiency anemia and acute lower respiratory tract Infection with an odds ratio of 7.76 and a significant p-value of <0.01. Conclusions: Iron deficiency anemia has an increased association of up to seven times in children with acute lower respiratory tract infections as compared to healthy children thus highlighting it as a significant risk factor.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jayaweera Arachchige Asela Sampath Jayaweera ◽  
Mohammed Reyes ◽  
Anpalaham Joseph

Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-021-90018-8.


2019 ◽  
Vol 67 (2) ◽  
pp. 341-347
Author(s):  
Norma Constanza Corrales-Zúñiga ◽  
Nelly Patricia Martínez-Muñoz ◽  
Sara Isabel Realpe-Cisneros ◽  
Carlos Eberth Pacichana-Agudelo ◽  
Leandro Guillermo Realpe-Cisneros ◽  
...  

Introducción. Es frecuente que muchos niños sometidos a procedimientos con anestesia general tengan historia de infección viral respiratoria superior reciente o activa.Objetivo. Realizar una revisión narrativa acerca de las pautas de manejo anestésico para los niños con infección reciente o activa de la vía aérea superior.Materiales y métodos. Se realizó una búsqueda estructurada de la literatura en las bases de datos ProQuest, EBSCO, ScienceDirect, PubMed, LILACS, Embase, Trip Database, SciELO y Cochrane Library con los términos Anesthesia AND Respiratory Tract Infections AND Complications; Anesthesia AND Upper respiratory tract infection AND Complications; Anesthesia, General AND Respiratory Tract Infections AND Complications; Anesthesia, General AND Upper respiratory tract infection AND Complications; Anesthesia AND Laryngospasm OR Bronchospasm. La búsqueda se hizo en inglés con sus equivalentes en español.Resultados. Se encontraron 56 artículos con información relevante para el desarrollo de la presente revisión.Conclusiones. Una menor manipulación de la vía aérea tiende a disminuir la frecuencia de aparición y severidad de eventos adversos respiratorios perioperatorios. No existe evidencia suficiente para recomendar la optimización medicamentosa en pacientes con infección respiratoria superior.


2009 ◽  
Vol 30 (10) ◽  
pp. 952-958 ◽  
Author(s):  
Fernando Bellissimo-Rodrigues ◽  
Wanessa Teixeira Bellissimo-Rodrigues ◽  
Jaciara Machado Viana ◽  
Gil Cezar Alkmim Teixeira ◽  
Edson Nicolini ◽  
...  

Objective.To evaluate the effectiveness of the oral application of a 0.12% solution of Chlorhexidine for prevention of respiratory tract infections among intensive care unit (ICU) patients.Design.The study design was a double-blind, randomized, placebo-controlled trial.Setting.The study was performed in an ICU in a tertiary care hospital at a public university.Patients.Study participants comprised 194 patients admitted to the ICU with a prospective length of stay greater than 48 hours, randomized into 2 groups: those who received Chlorhexidine (n = 98) and those who received a placebo (n = 96).Intervention.Oral rinses with Chlorhexidine or a placebo were performed 3 times a day throughout the duration of the patient's stay in the ICU. Clinical data were collected prospectively.Results.Both groups displayed similar baseline clinical features. The overall incidence of respiratory tract infections (RR, 1.0 [95% confidence interval [CI], 0.63-1.60]) and the rates of ventilator-associated pneumonia per 1,000 ventilator-days were similar in both experimental and control groups (22.6 vs 22.3; P = .95). Respiratory tract infection-free survival time (7.8 vs 6.9 days; P = .61), duration of mechanical ventilation (11.1 vs 11.0 days; P = .61), and length of stay (9.7 vs 10.4 days; P = .67) did not differ between the Chlorhexidine and placebo groups. However, patients in the Chlorhexidine group exhibited a larger interval between ICU admission and onset of the first respiratory tract infection (11.3 vs 7.6 days; P = .05). The chances of surviving the ICU stay were similar (RR, 1.08 [95% CI, 0.72-1.63]).Conclusion.Oral application of a 0.12% solution of Chlorhexidine does not prevent respiratory tract infections among ICU patients, although it may retard their onset.


2021 ◽  
Vol 41 (1) ◽  
pp. 111-114
Author(s):  
Shatanik Sarkar ◽  
Chaitali Patra ◽  
Shibani Pal ◽  
Arkapriya Pramanik

Recurrent respiratory tract infections, a cause of concern for both parents and paediatricians, can have various etiologies entitled to different organ systems. Diagnosing the exact cause warrants both clinical acumen and timely investigations. Here, we are reporting an infant with recurrent respiratory tract infections, where adequate clinical examination prompted us to diagnose the extra-respiratory cause with simple investigations.


Author(s):  
Merry Sunaryo

Dust is one type of potential hazardzs in the workplace that can affect the health of the workers. The occupation that are always exposed to dust is furniture industry workers so that they have higher risk of getting acute respiratory tract infection (ARI) disorder which can interfere with breathing. The wood dust is formed from some of the sawn wood and sanding that will lead to an acute respiratory tract infection. The study aimed to determine the effect of environmental factor and the use of Personal Protective Equipment (PPE) against the symptoms of acute respiratory infections in the furniture industry workers. The research method used was quantitative method with observational and cross-sectional research types and it was analysed by using logistic regression test. The population in this study was the workers of the furniture industry at Semarang street, Surabaya City, with a total of 57 people, of which 37 furniture workers as a sample. The results show that most of the workers has symptoms of acute respiratory tract infection. It could be influenced by the environmental factor such as dust exposure that produced wood dust in each manufacturing processes. Additionally, the use of PPE also affected the occurrence of acute respiratory tract infections symptoms in the workers. In conslusion, many factors can influence the occurrence of acute respiratory tract infection symptoms in the furniture industry workers. Therefore, it is necessary to minimize the dust exposure in workers by wearing PPE such as respirators.


2020 ◽  
Author(s):  
Sascha Accounts ◽  
Lucy Yardley ◽  
Peter Smith ◽  
Mark Weal ◽  
Alexander Milton ◽  
...  

BACKGROUND Around 57 million doctor appointments annually in the UK are for minor ailments that could be self-cared for by patients. As well as taking up healthcare resources, patients experience increased anxiety, lowered confidence and inconvenience. The ‘Internet Dr’ is a digital intervention developed to support patients to self-care for respiratory tract infections. In a randomised controlled trial, patients with access to the intervention had fewer visits to their doctor for respiratory tract infections. Having established intervention efficacy, further examination of the data collected in the trial is required to understand how the intervention was successful. OBJECTIVE This paper reports a process evaluation of the ‘Internet Dr’ intervention. The evaluation identifies meaningful usage metrics (ie, types of interaction that are specific and relevant to the intervention). These metrics are used to examine which parts of the intervention are effective in supporting self-care for respiratory tract infections, who used them and at what time. METHODS The ‘Internet Dr’ trial recorded patients’ characteristics and usage data over 24 weeks. At follow-up users reported changes in their levels of enablement to cope with their illness over the trial period. An evaluation plan to examine this data was developed using Medical Research Council guidance and the framework for Analysing and Measuring Usage and Engagement Data. RESULTS Viewing pages containing advice on caring for respiratory tract infections was identified as a meaningful metric for measuring usage of the intervention. Almost half the users (n=616, 42.32%) viewed at least one advice page, with most people (n=478, 77.60%) accessing them when they initially enrolled in the study. Users who viewed an advice page (M=2.12) reported increased enablement to cope with their illness as a result of having participated in the study (MD =.469, 95% CI [.082, .856]), compared to users who did not view advice pages (M=1.65). Users who had visited their GP for a respiratory tract infection in the year prior to the trial were a target population, and analyses revealed that this group were more likely to access advice pages (Wald's x2=14.915, P=<.001). CONCLUSIONS The process evaluation identifies viewing advice pages as associated to increased enablement to self-care, even when accessed in the absence of a respiratory tract infection, meaning that dissemination activities need not be restricted to targeting users who are ill. The intervention was also effective at reaching the target population of users who consulted their GP previously. However, attrition prior to advice pages was high, highlighting the necessity of prioritising access during the design phase. These findings provide guidance on how the intervention may be improved and disseminated, and have wider implications for minor ailment interventions. CLINICALTRIAL ISRCTN91518452


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