scholarly journals Vitamin D, Calcium, Alkaline Phosphatase, and Parathyroid Hormone in Patients with and without Chronic Periodontitis

2020 ◽  
Vol 4 (2) ◽  
pp. 51-56
Author(s):  
Shaili Pradhan ◽  
Shweta Agrawal ◽  
Benju Shrestha
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Chronic Periodontitis ◽  
Soft Tissues ◽  
Periodontal Diseases ◽  
Serum Vitamin ◽  
Tooth Surface ◽  
Dental Surgery ◽  
Serum Vitamin D

 Introduction: Periodontal diseases comprise a group of inflammatory diseases caused by bacteria that colonise the tooth surface and infect surrounding soft tissues, ultimately leading to tooth loss. Vitamin D, calcium, alkaline phosphatase, and parathyroid hormone have role in bone metabolism both in health or in disease. Objective: To compare serum Vitamin D, calcium, alkaline phosphatase, and parathyroid hormone levels in patients with generalised chronic periodontitis and healthy periodontium. Methods: A cross-sectional analytical study was done in 80 patients visiting Department of Dental Surgery from July to December 2019. Clinical parameters measured were plaque index, gingival index, clinical attachment level, and pocket depth in the healthy periodontium and generalised chronic periodontitis. Blood investigation for serum Vitamin D, calcium, alkaline phosphatase (ALP), and parathyroid hormone (PTH) level were done. Data was analysed in SPSS v.16. Results: Out of total 80 patients enrolled (mean age of 36.20±7.37 years), 40 (50%) patients had healthy periodontium and 40 (50%) had generalised chronic periodontitis. Mean levels of serum Vitamin D (P=0.006) and calcium (P=0.020) were significantly higher in chronic periodontitis patient compared to healthy controls while no significant intergroup differences were seen with respect to ALP (P=0.267) and PTH (P=0.351). Conclusion: No significant differences were found in the levels of ALP and PTH between generalised chronic periodontitis and healthy patients and higher levels of Vitamin D and calcium were seen in generalised chronic periodontitis patients as compared to healthy patients.

scholarly journals Thecomparisonofserumbiomarkersin patients with osteoarthritisand rheumatoidarthritis

2018 ◽  
Vol 6 (2) ◽  
pp. 1-11
Author(s):  
Almandlawi S G ◽  
Ahmed A S
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Calcium Phosphate ◽  
Serum Vitamin ◽  
Type Ii Collagen ◽  
Healthy Controls ◽  
Type Ii ◽  
Serum Vitamin D

Introduction: This study aims to assess the status of serum vitamin D, parathyroid hormone, type II collagen, calcium, phosphate,albumin, and alkaline phosphatase in osteoarthritis and rheumatoidarthritis patients and to study their association with rheumatoid arthritis disease activity. Materials and Methods: This prospectivecross-sectional study was conducted at the clinical analysis department, College of Pharmacy, Hawler Medical University in 2017.They study samples were collected at Rizgary Teaching Hospitalduring the period September 2015 to January 2016. A total of(N=156) participants were included: (N=53) patients with rheumatoid arthritis (RA), (N=53) with osteoarthritis (OA), and (N=50)healthy controls. Enzyme Linked Immuno Sorbent Assay kits determined serum vitamin D, parathyroid hormone, and type II collagen; and serum albumin, calcium, phosphate and alkaline phosphatase, were determined by standard colorimetric methods. Resultsand Discussion: Statistically significant higher levels of parathyroid hormone and type II collagen, with lower levels of Vitamin D,were found in the osteoarthritis group than the rheumatoid arthritisgroup and the healthy controls (P=0.007, P<0.001, P= 0.005) respectively. Multiple linear regression showed a statistically significant difference in serum type II collagen as a dependent variable, inpatients suffering from RA or OA compared to the healthy controlgroup; after adjusting for the effect of other independent studyvariables, there was a mean increase of (45.90 nmol/L, P<0.001)in RA patients, and OA patients showed greater levels of type IIcollagen (73.950 nmol/L) than the health control group (P<0.001).Conclusions: Elevated type II collagen levels, in conjunction witha low vitamin D status, may be strong discriminator between osteoarthritis and rheumatoid arthritis patients.

scholarly journals Serum Vitamin D in Patients with Chronic Periodontitis and Healthy Periodontium

2021 ◽  
Vol 18 (4) ◽  
pp. 610-614
Author(s):  
Shaili Pradhan ◽  
Shweta Agrawal
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Chronic Periodontitis ◽  
Serum Vitamin ◽  
Periodontal Pocket ◽  
P Value ◽  
Dental Surgery ◽  
Clinical Attachment Level ◽  
Serum Vitamin D ◽  
Attachment Level

Background: Periodontitis is inflammatory disorder resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation, recession, or both. Vitamin D has a benefit in bone metabolism and anti-inflammatory activity involving T-cell homeostasis. The objective of this study was to compare the vitamin D level in patient with chronic periodontitis and healthy periodontium and evaluate its correlation.Methods: A comparative cross-sectional study was done in 80 patients (40 with healthy periodontium and 40 with chronic periodontitis) visiting to Department of Dental Surgery (Periodontology and Oral Implantology Section) of Bir Hospital. Parameters measured were plaque index, gingival index, clinical attachment level and pocket depth for the evaluation of healthy periodontium and chronic periodontitis. Results: The result showed 16.58±6.65ng/mL and 19.06±11.52ng/mL level of vitamin D in female and male respectively (p-value 0.230) and 16.85±13.30 ng/mL and 19.78±5.87 ng/mL level of vitamin D in healthy and chronic periodontitis groups respectively (p-value 0.209).Conclusions: There are no differences in the level of serum vitamin D between healthy and chronic periodontitis groups. No association was seen between vitamin D level and chronic periodontitis.Keywords: Bone metabolism; chronic periodontitis; clinical attachment level; healthy periodontium; vitamin D; periodontal pocket

scholarly journals Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American—Diabetes Heart Study

Bone ◽  
2016 ◽  
Vol 87 ◽  
pp. 71-77 ◽  
Author(s):  
Nicholette D. Palmer ◽  
Jasmin Divers ◽  
Lingyi Lu ◽  
Thomas C. Register ◽  
J. Jeffrey Carr ◽  
...  
Keyword(s):  
Vitamin D ◽  
African American ◽  
Parathyroid Hormone ◽  
Serum Vitamin ◽  
Admixture Mapping ◽  
Serum Vitamin D ◽  
Heart Study ◽  
Diabetes Heart Study

scholarly journals Relationship between Parathyroid Hormone Level and Early Remodeling Heart Failure after Acute Myocardial Infarction

2020 ◽  
Author(s):  
Zohreh Firouzi ◽  
Saeideh Mahdizadeh Sajjadieh ◽  
Saeideh Mahdizadeh Sajjadieh ◽  
Maryam Mousavi ◽  
Zahra Erfanian ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Acute Myocardial Infarction ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Serum Vitamin ◽  
Current Evidence ◽  
Serum Vitamin D ◽  
Serum Pth ◽  
Pth Level

Background: Previous studies have indicated that parathyroid hormone (PTH) has been linked to post-myocardial infarction (MI) development. The aim of this cross-sectional study was to evaluate the relationship between PTH level and heart failure due to post infarction remodeling during the first 72 hours of hospitalization. Methods: Seventy patients with a diagnosis of acute MI (age ≥18 years, 22 females and 48 males) were enrolled. Patients were admitted to the Imam Raza Educational, Research and Treatment Center, Mashhad University of Medical Sciences, Iran between July 2014 to September 2015. We measured PTH and vitamin D level. Blood samples were taken after 24 hours and 72 hours. Results: During the first 72 hours, the PTH level significantly increased in patients with Post-MI heart failure. 68% of the subjects had an inappropriate vitamin D level at the time of admission. Mean levels of vitamin D and PTH increased compared with the baselines (95% CI, 0.15 to 10.03, P: 0.044), (95% CI, 6.5 to 24.8, P:0.001) respectively. Conclusion: Acute elevations of serum PTH levels increased early remodeling heart failure after MI. Serum vitamin D status was independent of high serum PTH level. Based on the current evidence, PTH excess may be a risk factor for heart failure, so early treatment and omitting risk factors are the most effective strategies for the patients with acute myocardial infarction. J Pharm Care 2020; 8(1): 11-15.

Seasonal Periodicity of Serum Vitamin D and Parathyroid Hormone, Bone Resorption, and Fractures: The Geelong Osteoporosis Study

2004 ◽  
Vol 19 (5) ◽  
pp. 752-758 ◽  
Author(s):  
Julie A Pasco ◽  
Margaret J Henry ◽  
Mark A Kotowicz ◽  
Kerrie M Sanders ◽  
Ego Seeman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Bone Resorption ◽  
Serum Vitamin ◽  
Seasonal Periodicity ◽  
Serum Vitamin D ◽  
Geelong Osteoporosis Study
Sign in / Sign up

Export Citation Format

Share Document