scholarly journals Histopathology of extra-pulmonary tuberculosis at pathology lab of Patan Hospital, Nepal

2020 ◽  
Vol 7 (3) ◽  
pp. 47-53
Author(s):  
Reetu Baral ◽  
Palzum Sherpa ◽  
Dipty Gautam ◽  
Shiva Raj KC
Keyword(s):  
Pulmonary Tuberculosis ◽  
Review Committee ◽  
Female Ratio ◽  
Extra Pulmonary Tuberculosis ◽  
Underdeveloped Countries ◽  
Institutional Review ◽  
Ethical Approval ◽  
Extra Pulmonary ◽  
Tubercular Lymphadenitis ◽  
Male To Female

Introduction: Tuberculosis is a common condition in underdeveloped countries, with approximately 100,000 cases in Nepal today. Tuberculosis is the 6th leading cause of death in Nepal. This study aims to find out the Extra Pulmonary Tuberculosis in the specimen received in the pathology lab. Method: This is a retrospective descriptive study of the histopathology database of Extra Pulmonary Tuberculosis at the pathology lab of Patan Hospital, Nepal from 2012 to 2019. Data were analyzed for prevalence, cite, and pathology details. Ethical approval was obtained from the Institutional review committee of Patan Hospital. Result: There were 300(1%) Extra Pulmonary Tuberculosis out of 29629 specimens. The majority 170(57%) were from the lymph nodes, 36(12%) skin, followed by intestine and urogenital each 28 and 26(9%). Male to female ratio was 2:3 (n=116, 39% vs n=184, 61%). The most common age group was 20-39 years comprising 194(64%). Granuloma was present in 288(96%), and 21(7%) tested positive for Acid Fast Bacilli. Conclusion:  Among the Extra Pulmonary Tuberculosis, more than half of them had tubercular lymphadenitis with granuloma present in the majority.

scholarly journals Epidemiology and the diagnostic challenge of extra-pulmonary tuberculosis in a teaching hospital in Ethiopia

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243945
Author(s):  
Balew Arega ◽  
Amdemeskel Mersha ◽  
Abraham Minda ◽  
Yitagesu Getachew ◽  
Alazar Sitotaw ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Teaching Hospital ◽  
Laboratory Diagnosis ◽  
High Rate ◽  
Diagnostic Challenge ◽  
Extra Pulmonary Tuberculosis ◽  
Histopathology Finding ◽  
Extra Pulmonary ◽  
Tubercular Lymphadenitis ◽  
Recorded Diagnosis

Background Ethiopia reported a high rate of extra-pulmonary tuberculosis (EPTB) and the cases are increasing since the last three decades. However, diagnostic evidence to initiate TB treatment among EPTB cases is not well known. Therefore, we described the epidemiology and assessed how EPTB is diagnosed in a teaching hospital in Ethiopia. Methods We conducted a retrospective review among all adult EPTB cases diagnosed in Yekatit 12 Hospital Medical College from 2015 to 2019. Using a standardized data abstraction sheet, we collected data from patients’ medical records on sociodemographic, sites, and laboratory diagnosis of EPTB cases. Results Of the 965 total TB cases, 49.8%(481) had a recorded diagnosis of EPTB during the study period. The mean age of EPTB patients was 32.9 years (SD±13.9) and 50.7% were males. Tubercular lymphadenitis (40.3%), abdominal (23.4%), and pleural TB(13.5%) were the most common sites of EPTB involvement, followed in descending order by the genitourinary, skeletal, central nervous system, abscess, breast, and laryngeal TB. We found a histopathology finding consistent with EPTB in 59.1% of cases, Acid-fast bacilli positive in 1.5%, and the rest diagnosed on radiological grounds. In the majority of cases, more than one diagnostic method was used to diagnose EPTB cases. Conclusions Nearly half of TB patients had a recorded diagnosis of EPTB that comprise heterogeneous anatomical sites. All EPTB patients were started anti-TB therapy without definitive microbiology results. This indicates the diagnostic challenge of EPTB faced in our setting and proves to be significant for TB control in Ethiopia.

scholarly journals Asymptomatic Isolated Cervical Tubercular Lymphadenopathy, How to Proceed?: A Case Series

2020 ◽  
Vol 9 (2) ◽  
pp. 1-5
Author(s):  
Ravi Singh Dogra ◽  
Arjun Singh ◽  
Vinay Bhardwaj ◽  
Poonam ◽  
Srijan Pandey ◽  
...  
Keyword(s):  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Case Series ◽  
The Body ◽  
Extra Pulmonary Tuberculosis ◽  
Female Predominance ◽  
Prevalent Disease ◽  
Extra Pulmonary ◽  
Tubercular Lymphadenitis

Tuberculosis is a highly prevalent disease in developing countries, the majority of cases are pulmonary and rest are extra-pulmonary. Cervical LN tuberculosis is one of the most common types of extra-pulmonary tuberculosis. Isolated cervical tubercular Lymphadenitis without accompanying pulmonary tuberculosis or another form of tuberculosis in the body is rare and, when present, requires thorough clinical examination and investigation. In the investigation of such patients, FNAC plays a major role, and aspirate should be tested for AFB through ZN stain and CBNAAT (PCR). Cervical tubercular Lymphadenitis is mainly a disease of young with a female predominance. All patients of cervical tubercular Lymphadenitis must receive antitubercular therapy with strict follow up for compliance and possible side effects from treatment.

scholarly journals Rapid diagnosis of extra pulmonary tuberculosis by automated Xpert MTB/RIF assay

2012 ◽  
Vol 12 (Suppl 1) ◽  
pp. P32 ◽  
Author(s):  
Shirly Suzana ◽  
Baby Shalini ◽  
Priscilla Rupali ◽  
K Venkatesh ◽  
DJ Christopher ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Rapid Diagnosis ◽  
Extra Pulmonary Tuberculosis ◽  
Extra Pulmonary

COMPARISON OF CLINICO-SOCIAL PROFILE OF PULMONARY AND EXTRA PULMONARY TUBERCULOSIS IN TERTIARY CARE HOSPITAL IN A RURALAREA: A RETROSPECTIVE STUDY

2021 ◽  
pp. 70-72
Author(s):  
Gaurav Santosh Nemade ◽  
Sumit Nitin Dhus ◽  
Arushi Ramesh Shetty ◽  
Neha Dhananjay Firake
Keyword(s):  
Tertiary Care ◽  
Care Hospital ◽  
Female Ratio ◽  
Extra Pulmonary Tuberculosis ◽  
Younger Age ◽  
Tobacco Addiction ◽  
History Of ◽  
Early Case ◽  
Male To Female ◽  
Clinical Characteristic

BACKGROUND AND OBJECTIVES: The burden of tuberculosis (TB) in India is the highest accounting for 26% of the global incidence. A total of 1.4 million people died from TB in 2019 (including 208 000 people with HIV). India accounts for a fourth of the global burden of TB and 29% of global mortality. Therefore, we carried out this study to compare demographic, lifestyle and clinical characteristic between pulmonary TB (PTB) and extrapulmonary TB (EPTB). MATERIALS AND METHODOLOGY:Aretrospective analysis was carried of 348 patients diagnosed in DOTS centre, Pravara Rural Hospital, Loni. Characteristics of demographic and clinical characteristics were obtained from medical case records. RESULTS:Among the 348 cases, 71.3% were PTB and 28.7% were EPTB including, pleural (36%), meningeal (27%) and lymphatic (20%) cases. The male to female ratio in PTB and EPTB are 1.99 and 1.22 respectively. EPTB was more common at younger age (<25 years). Tobacco addiction (10.9%), diabetes mellitus (4.03%), HIV positivity (12.1%) and history of contact with Tb patients (17.7%) were more likely to be associated with PTB. CONCLUSION:Increased awareness of the risk factors may facilitate early case nding and better management outcomes for these patients.

An accurate artificial intelligence system for the detection of pulmonary and extra pulmonary Tuberculosis

Tuberculosis ◽  
2021 ◽  
pp. 102143
Author(s):  
Anshu Sharma ◽  
Anurag Sharma ◽  
Rahul Malhotra ◽  
Parulpreet Singh ◽  
Ripon K. Chakrabortty ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Pulmonary Tuberculosis ◽  
Artificial Intelligence System ◽  
Extra Pulmonary Tuberculosis ◽  
Intelligence System ◽  
Extra Pulmonary
Sign in / Sign up

Export Citation Format

Share Document