Adenomyoepithelioma of breast

Adenomyoepithelioma of breast is a rare, benign proliferative tumor formed of proliferationof myoepithelial cells surrounding small epithelium lined spaces. We present two cases ofadenomyoepithelioma of the breast. The irst case was of a 23-years-old female with right breast lump and the second of a 41-year-old female with left breast lump. No patient had prior, coexistent carcinoma of either breast. None had any family history of breast cancer either. Excisional biopsy, Hematoxylin and Eosin staining and immunohistochemistry with S100 were performed. The pathological diagnosis was adenomyoepithelioma.

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Adenomyoepithelioma of the Breast

Tumori Journal ◽

10.1177/030089160709300515 ◽

2007 ◽

Vol 93 (5) ◽

pp. 493-495 ◽

Cited By ~ 5

Author(s):

Chun-Ying Huang ◽

Shyr-Ming Sheen-Chen ◽

Hock-Liew Eng ◽

Sheung-Fat Ko

Keyword(s):

Frozen Section ◽

Color Doppler ◽

Myoepithelial Cells ◽

Left Breast ◽

Full Description ◽

Breast Lump ◽

Supraclavicular Lymph Nodes ◽

History Of ◽

Immunohistochemical Studies ◽

Uncommon Tumor

Adenomyoepithelioma of the breast is an uncommon tumor characterized by the presence of both epithelial and myoepithelial cells; its first full description was published in 1970 by Hamperl. A 45-year-old woman presented a left breast lump that had been palpable for 4 weeks. There was no family history of breast cancer. Neither axillary nor supraclavicular lymph nodes were palpable. Craniocaudal mammography showed a 1.6 cm, well-defined nodule with several punctate intranodular calcifications in the subareolar region of the left breast. Color Doppler sonogram showed an ovoid, well-defined, homogeneous hypoechoic subareolar nodule with prominent peripheral vessels in the 6 o'clock position of the left breast. Operation was arranged and intraoperative frozen section examination revealed proliferation of round, oval or tubular glandular elements with intervening islands and bands of polygonal myoepithelial cells. Adenomyoepithelioma of the breast was the impression. Wide excision with adequate removal of the tumor and preservation of the left breast contour was successfully achieved. The diagnosis of adenomyoepithelioma of the breast was confirmed by immunohistochemical studies.

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Case 15.14

Mayo Clinic Body MRI Case Review ◽

10.1093/med/9780199915705.003.0397 ◽

2014 ◽

pp. 752-753

Author(s):

Christine U. Lee ◽

James F. Glockner

Keyword(s):

Breast Cancer ◽

Family History ◽

Surgical Excision ◽

Left Breast ◽

Strong Family History ◽

Peak Enhancement ◽

History Of ◽

Baseline Screening

36-year-old woman with a strong family history of breast cancer and a remote history of surgical excision of a 3-cm fibroadenoma at 16 years of age; this examination was performed as a baseline screening MRI The MIP images of the left breast at peak enhancement with (...

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Case 15.15

Mayo Clinic Body MRI Case Review ◽

10.1093/med/9780199915705.003.0398 ◽

2014 ◽

pp. 754-755

Author(s):

Christine U. Lee ◽

James F. Glockner

Keyword(s):

Breast Cancer ◽

Family History ◽

High Risk ◽

High Risk Patient ◽

Excisional Biopsy ◽

Risk Patient ◽

Strong Family History ◽

Guided Biopsy ◽

History Of

41-year-old woman with strong family history of breast cancer and a right breast stereotactic-guided biopsy of calcifications 6 months ago that demonstrated ALH. This patient subsequently underwent surgical excisional biopsy with no higher-grade lesion detected; MRI was performed for screening purposes in this high-risk patient...

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Primary MALT Lymphoma of the Breast Treated with Definitive Radiation

Case Reports in Hematology ◽

10.1155/2016/1831792 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Mohammad Hissourou III ◽

Sayyad Yaseen Zia ◽

Mahfood Alqatari ◽

James Strauchen ◽

Richard L. Bakst

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Family History ◽

Malt Lymphoma ◽

Current Literature ◽

Marginal Zone ◽

Left Breast ◽

Marginal Zone Lymphoma ◽

Rare Presentation ◽

History Of

We are reporting a case of a 59-year-old woman, with a family history of breast cancer, who presented with extranodal marginal zone lymphoma (MALT) of the left breast. She received definitive radiation therapy and remains without evidence of disease. Here, we present a case and review the current literature to determine the optimal treatment of this rare presentation of MALT.

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Multivariate analysis of predictors of positive or close margins in breast-conserving therapy.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.27_suppl.105 ◽

2011 ◽

Vol 29 (27_suppl) ◽

pp. 105-105

Author(s):

A. Chokechanachaisakul ◽

C. A. Wesen ◽

T. M. Hall ◽

J. S. Falk

Keyword(s):

Breast Cancer ◽

Family History ◽

Ductal Carcinoma ◽

Excisional Biopsy ◽

Breast Conserving Therapy ◽

Cosmetic Outcome ◽

Close Margin ◽

Palpable Mass ◽

Increased Risk ◽

History Of

105 Background: Local recurrence rates after breast-conserving therapy (BCT) are increased with positive or close margin lumpectomy. This group of patients usually requires a re-excision lumpectomy or a completion mastectomy, causing delays in systemic therapy, and a less desirable cosmetic outcome. The objectives of this study were to identify any predictive risk factors that might be associated with positive or close lumpectomy margins (<1mm), and thus have implications for the planning of appropriate primary surgical excision. Methods: This was a retrospective cohort study of 195 consecutive patients from a prospectively collected, single-institution database. Patients who underwent primary lumpectomy for ductal carcinoma in situ (DCIS), invasive ductal carcinoma, and invasive lobular carcinoma from October 2007 to July 2010 were reviewed. Statistical analysis of the data was performed using Chi-squared analyses, multivariate logistic regression and Student’s t-test to identify significant predictors of a close or positive margin following lumpectomy. Results: In this study, 53.8% had positive or close margins. Ninety-two percent of this group underwent re-excision (86.5%) and total mastectomy (13.5%). We also observed that 53.1% of patients who underwent second operation had no residual disease. Factors significantly associated with positive or close margins include a family history of breast cancer (OR=2.3, p=0.01), a non-palpable mass (OR=2.4, p=0.01), or an excisional biopsy (OR=6.02, p=0.022). Age, race, use of hormone replacement therapy, menopausal status, use of preoperative MRI or US, BIRAD, use of neoadjuvant chemotherapy, tumor size, staging, waiting time, histology, receptor status, and axillary status were not significantly correlated with positive or close margins. Conclusions: For patients who were recommended to have a lumpectomy, an increased risk of a positive or close margin was significantly associated with a family history of breast cancer, a nonpalpable mass, or an excisional biopsy. These predictors should be weighed in the decision for attempting lumpectomy with the goal of a negative margin versus the ability to obtain a satisfactory cosmetic outcome.

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Rosai-Dorfman Disease Presenting as a Male Breast Mass

The American Surgeon ◽

10.1177/000313480707300322 ◽

2007 ◽

Vol 73 (3) ◽

pp. 294-295 ◽

Cited By ~ 2

Author(s):

Anton S.N. Dias Perera ◽

Angela J. Keleher ◽

Manju Nath

Keyword(s):

Breast Cancer ◽

Surgical Resection ◽

Excisional Biopsy ◽

Left Breast ◽

Male Breast ◽

Breast Mass ◽

Appropriate Treatment ◽

Rosai Dorfman Disease ◽

History Of

A 23-year-old man presented with a 6-week history of a left breast mass. Mammography and ultrasonography confirmed a 1.1 x 0.7-cm mass suggestive of breast cancer. An excisional biopsy revealed Rosai-Dorfman disease of the breast. As illustrated by this case, extranodal Rosai-Dorfman disease can mimic breast cancer. Surgical resection is considered appropriate treatment for this condition.

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MR-guided intervention in women with a family history of breast cancer

Yearbook of Diagnostic Radiology ◽

10.1016/s0098-1672(08)70045-6 ◽

2007 ◽

Vol 2007 ◽

pp. 58-59

Author(s):

R.L. Birdwell

Keyword(s):

Breast Cancer ◽

Family History ◽

History Of

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Family history of breast cancer and local recurrence after breast conserving therapy

European Journal of Cancer ◽

10.1016/s0959-8049(98)80040-3 ◽

1998 ◽

Vol 34 ◽

pp. S12

Author(s):

C.T.M. Brekelmans ◽

A.C. Voogd ◽

G. Botke ◽

A.N. van Geel ◽

P. Rodrigus ◽

...

Keyword(s):

Breast Cancer ◽

Family History ◽

Local Recurrence ◽

Breast Conserving Therapy ◽

History Of

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A Group Therapy Approach to Facilitate Integration of Risk Information for Women at Risk for Breast Cancer

The Canadian Journal of Psychiatry ◽

10.1177/070674379804300405 ◽

1998 ◽

Vol 43 (4) ◽

pp. 375-380 ◽

Cited By ~ 17

Author(s):

Mary Jane Esplen ◽

Brenda Toner ◽

Jonathan Hunter ◽

Gordon Glendon ◽

Kate Butler ◽

...

Keyword(s):

Breast Cancer ◽

At Risk ◽

Family History ◽

Group Therapy ◽

Perceived Risk ◽

Positive Family History ◽

Risk Information ◽

Degree Relative ◽

Therapy Approach ◽

History Of

Objective: To describe and illustrate elements of a group counselling approach designed to enhance the communication of risk information on breast cancer (BC) to women with a family history of this disease. Breast cancer is a leading cause of female cancer death. The most important risk factor for BC is a positive family history in at least 1 first-degree relative, and approximately one-third of women with BC have a family history of the disease. Recent evidence suggests that there is a significant psychological impact associated with having a family history of BC, and this may influence the psychological adjustment and response to being counselled for personal risk. New counselling approaches are required. Method: This paper describes a group therapy approach that incorporates principles of supportive-expressive therapy designed to address the emotional impact of being at risk for BC and to promote accuracy of perceived risk. The key elements of the intervention are described along with clinical illustrations from groups that are part of an ongoing study to develop and standardize the group therapy. Conclusion: Qualitative data from the groups suggest that this model of therapy is both feasible and effective.

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