scholarly journals Hepatoblastoma in a 14-months old child

2021 ◽  
Vol 5 (1) ◽  
pp. 80-82
Author(s):  
Rashes Shrestha ◽  
Niraj Bhattarai ◽  
Binay Thakur ◽  
Mukti Devkota ◽  
Rajesh Kumar Mandel ◽  
...  

In children, commonest liver tumor is hepatoblastoma. We present a 14-month-old male child who presented with abdominal distension and loose stool. Radiological imaging revealed solid hepatic mass. Hematological investigations revealed anemia, thrombocytosis and high Serum alpha fetoprotein (AFP) level. Ultrasound (USG) guided FNAC confirmed the mass to be hepatoblastoma. CT scan revealed hepatoblastoma PRETEXT stage III. The patient underwent 6 cycles of neoadjuvant chemotherapy and responded to POSTTEXT stage II. Left hemi-hepatectomy was done with clear resectin margins. Complete surgical excision of the mass after preoperative chemotherapy remains the mainstay of the treatment of locally advanced hepatoblastoma. 

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Mahendra Singh ◽  
Lovekesh Kumar ◽  
Rajkumar Chejara ◽  
Om Prakash Prasad ◽  
Yuvraj Kolhe ◽  
...  

Schwannoma is a benign tumour of peripheral nerve sheath. It usually arises from head, neck, and trunk. Retroperitoneal schwannoma is a rare entity, accounting for only 0.3–3% of total schwannomas. Majority of retroperitoneal schwannomas reported in literature have a diameter of 5 to 15 cm. Preoperative diagnosis is difficult due to low frequency, nonspecific clinical course, and nonspecific imaging features. Histology usually provides definitive diagnosis. Schwannomas are solitary, well-circumscribed, and noninvasive, so complete surgical excision provides good result. We report a case of a 23-year-old male, who presented with progressive abdominal distension and intermittent episodes of intestinal obstruction. CECT was suggestive of huge solid-cystic mass in abdominopelvic region. Image guided percutaneous aspiration revealed around 1 litre of frank pus and FNAC was suggestive of abscess. Exploratory laparotomy revealed a large 32 × 28 × 26 cm mass with solid and cystic components containing 1 litre of pus. Histological features of tumour were suggestive of benign schwannoma and immunohistochemistry for S-100 was positive. Postoperative recovery was uneventful. We report this case of a retroperitoneal schwannoma because of giant size, rare location, unusual presentation, and diagnostic dilemma.


1998 ◽  
Vol 112 (9) ◽  
pp. 893-894 ◽  
Author(s):  
F. Rapado ◽  
J. D. C. Bennett ◽  
J. M. Stringfellow

AbstractBronchogenic cysts are rare congenital benign lesions that are usually detected in the paediatric patient with symptoms of infection or compression on vital structures. They are rarely diagnosed in the adult population. We present a case of bronchogenic cyst presenting as a lump in the neck in an adult patient. Radiological imaging helped to diagnose this lesion accurately before any form of intervention. Complete surgical excision is the treatment of choice.


2021 ◽  
Vol 7 (2) ◽  
pp. 28-31
Author(s):  
Deki Choden ◽  
Kinley Sangay Dorji ◽  
Sonam Choden

ABSTRACTRetroperitoneal teratoma is a extragonadal germ cell tumor comprising 5% of all teratomas in children, and the third most common retroperitoneal neoplasm in children. This is a case report of a 2 years old girl who presented with abdominal distension and palpable mass. The imaging findings of the mass was characteristic of retroperitoneal teratoma which was confirmed by histopathology report following complete excision. Retroperitoneal tumor is an uncommon tumor in children with characteristic imaging findings. Computed tomography is mainly used to evaluate the extent of the disease. Most of the retroperitoneal tumors are benign and curable with complete surgical excision.


Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5691
Author(s):  
Sacha Nahon-Estève ◽  
Corine Bertolotto ◽  
Alexandra Picard-Gauci ◽  
Lauris Gastaud ◽  
Stéphanie Baillif ◽  
...  

Although its incidence has increased over the last decades, conjunctival melanoma (CM) remains a rare but challenging periocular malignancy. While there is currently no recognized standard of care, “no-touch” surgical excision followed by adjuvant treatments is usually recommended. Despite its small size, managing CM is challenging for clinicians. The first challenge is the high risk of tumour local recurrence that occurs in about one third of the patients. The management of locally advanced CM (≥T2) or multiple recurrences may require mutilating surgeries such as orbital exenteration (OE). The second challenge is the metastatic spread of CM that occurs in about one quarter of patients, regardless of whether complete surgical excision is performed or not. This highlights the infiltrative and highly aggressive behaviour of CM. Recently, attention has been directed towards the use of eye-sparing strategies to avoid OE. Initially, wide conservative surgeries followed by customized brachytherapy or radiotherapy have appeared as viable strategies. Nowadays, new biological insights into CM have revealed similarities with cutaneous melanoma. These new findings have allowed clinicians to reconsider the management of locally advanced CM with “medical” eye-sparing treatment as well as the management of metastatic spread. The aim of this review was to summarize the current and future perspectives of treatment for CM based on recent biological findings.


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
S. Burkart ◽  
U. Schoenenberger

Vascular leiomyomas or angioleiomyomas are rare tumors that can be found in the nasal cavity. The etiology of angioleiomyoma remains poorly understood and there are several hypotheses to explain the origin of sinonasal leiomyoma. We here describe the clinical and histological findings in a case study along with the feasibility of surgical treatment using a radiofrequency instrument. In particular, we describe the case of an adult patient with recurrent epistaxis because of a nasal angioleiomyoma and the performed treatment in the form of complete surgical excision. Radiological imaging is a helpful tool to give an indication of the extension of the tumor, as well as for the proper planning of the surgical approach. Either MRI or CT scans are found to be best suited for this purpose. This case report recommends the complete surgical excision of the angioleiomyoma, by either an endoscopic or an open procedure. This can be safely performed using a radiofrequency instrument as shown in this case with no recurrence during a follow-up of 12 months.


2021 ◽  
Author(s):  
Xiang-Yu Long ◽  
Shuang Zhang ◽  
Lian-sha Tang ◽  
Xiang Li ◽  
Jiyan Liu

Abstract Background: Locally advanced Penile squamous cell carcinoma (PSCC) with unresectable inguinal lymph nodes has a poor prognosis, and benefits from surgical treatment alone. Effective conversion therapy regimens are urgently needed.Case Presentation: We report a locally advanced PSCC patient with bulky, fixed inguinal lymph node metastasis complicated within genial skin ulcers, who completed inguinal lymph node dissection and achieved pathologically complete response via conversion therapy by immunotherapy plus chemotherapy.Conclusion: For unresectable locally advanced PSCC, neoadjuvant immunotherapy combined with chemotherapy is a potential treatment approach. Biomarkers of immune efficacy need to be explored. At the same time, clinical trials are needed to test the notions.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e21116-e21116
Author(s):  
Lei Yu

e21116 Background: Thymoma is a kind of mediastinal tumors usually with an indolent growth pattern but malignant because of potential for local invasion, pleural dissemination, and even systemic metastases. Different from other malignant tumors, thymoma is often associated with autoimmune disorder s, the most common one being myasthenia gravis (MG). Complete surgical excision has been regarded as the standard of care for patients with thymoma, esp. locally advanced thymoma. The aim of this study was to investigate the effectiveness of reconstruction (Y-shaped bypass) of the superior vena cava (SVC) to treat locally advanced thymoma with SVC syndrome. Methods: We retrospectively studied data from 24 consecutive patients with locally advanced thymoma and SVC syndrome, operated on from October. 2015 to Dec. 2018 in Beijing Tongren Hospital. Their clinical data including clinical presentation, operation procedure, postoperative drug, adjuvant radiochemotherapy and follow-up were documented. 18 cases had MG, one having dermatomyositis, and two having interstitial pneumonia. Results: There were no perioperative deaths. All patients underwent complete resection and replacement with a GORE-TEX Vascular Graft (Y-shaped bypass) of SVC. The number of typeAB, B1, B2, B3 thymoma, and thymic carcinoma in this data were 2, 2, 7, 7, and 6, respectively. 7 patients had postoperative complications: 3 (with MG) experienced myasthenia crisis, 3 had pneumonia, and one had pulmonary embolisms, respectively. Both unfractionated heparin and Warfarin were routinely used the second or third day after surgery to maintain INR (International Normalized Ratio) between 1.8 and 2.5. All patients received mediastinal radiation therapy within one month after surgery. All patients were followed up for 2 months to 42 months. There were no patients dying and recurring. Conclusions: Reconstruction of SVC (Y-shaped bypass) is an effective way to treat locally advanced thymoma with SVC syndrome. After surgery, postoperative anti-thrombotic agents should be applied to prevent acute graft occlusion.


2021 ◽  
Vol 14 (5) ◽  
pp. e243302
Author(s):  
Kazuki Mitani ◽  
Elena Yukie Uebayashi ◽  
Hisanori Fujino ◽  
Shinichi Sumimoto

A 9-month-old girl presented with progressive abdominal distension. Imaging revealed a huge cystic mass in the left retroperitoneum with solid components. The right kidney was absent and hydrometrocolpos was found. Tumour drainage and complete surgical excision were performed. A bulge in the right side of the uterus, suggestive of a uterine anomaly, was seen on laparoscopic observation. Pathology was consistent with teratoma with a small portion of immature neural tissue. The patient was discharged in good condition and was advised regular follow-up.


Author(s):  
I. Gusti Ayu Agung Bella Bella Jayaningrum ◽  
Pande Made Gunawan Adiputra

Teratomas are neoplasms of the embryonic tissues that typically grow in the gonadal and sacrococcygeal regions of adults and children. Intrabdominal teratomas that occur in adolescent are rare and demand challenging management options. We report a case of an intraabdominal mature cystic teratoma in a 17-year-old female patient. Complete resection of the mass was performed by a laparotomy approach. Radiological imaging is helpful in preoperative diagnosis and planning. Multidisciplinary surgical team planning is also essential to avoid injury to the adjacent organs in duodenal teratoma operation. Complete surgical excision is the treatment of choice, and the prognosis of mature teratomas is excellent.  


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