scholarly journals Serum calcium level among pregnant women and its association with pre-eclampsia and delivery outcomes: A cross-sectional study from North India

2019 ◽  
Vol 9 (4) ◽  
pp. 795-803 ◽  
Author(s):  
Shashi Kant ◽  
Partha Haldar ◽  
Anant Gupta ◽  
Ayush Lohiya
Keyword(s):  
Pregnant Women ◽  
Neonatal Mortality ◽  
Preterm Delivery ◽  
Serum Calcium ◽  
Calcium Intake ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Care Hospital

Background: Calcium requirement increases during pregnancy, thereby increasing the chances of developing hypocalcaemia. Hypocalcaemia may be associated with pregnancy-related complications. Therefore, we planned this study to estimate the prevalence of hypocalcaemia among pregnant women attending secondary care hospital, and to study the association between hypocalcaemia and pregnancy outcomes. Materials and Methods: This study was conducted in a secondary level hospital at Ballabgarh, district Faridabad, Haryana, India. Consecutive pregnant women with gestation period more than 28 weeks were enrolled. Dietary calcium intake was ascertained using 24-hour dietary recall method. Serum calcium estimation was done by Biolis 24i auto analyser. Outcome of pregnancy (preterm delivery, low birth weight (LBW) babies, and neonatal mortality) was assessed telephonically 3 months after the enrolment. Results: A total of 696 pregnant women were enrolled in the study. Mean (SD) dietary calcium intake and serum calcium level was 796.4 (360.4) mg/day and 9.56 (0.94) mg/dl respectively. Prevalence (95% CI) of hypocalcaemia was 23.9% (20.8 – 27.2%). Serum total calcium level was not associated with dietary calcium intake (p-value – 0.36). Mean serum calcium level was significantly lower in mothers who had LBW babies. Pre-eclampsia, preterm delivery, and neonatal mortality were not associated with serum calcium level. Conclusion: Serum calcium level may not be related to dietary calcium level. Hence, the current recommendation of calcium supplementation during antenatal period appears to be inconclusive among our study population.

scholarly journals Association of dietary calcium intake, total and ionized serum calcium levels with preeclampsia in Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rahel D. Gebreyohannes ◽  
Ahmed Abdella ◽  
Wondimu Ayele ◽  
Ahizechukwu C. Eke
Keyword(s):  
Serum Calcium ◽  
Calcium Intake ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Dietary Calcium ◽  
Ionized Calcium ◽  
Dietary Calcium Intake ◽  
Total Serum ◽  
Total Serum Calcium ◽  
Total Serum Calcium Level

Abstract Background Preeclampsia is a well-known cause of maternal mortality and morbidity in Ethiopia. The exact pathophysiology has not been fully understood. Calcium and magnesium deficiencies have been given emphasis to play roles in the pathophysiology. Although evidence is abundant, they are equivocal. The study aimed to see the association of dietary calcium intake, serum total calcium level and ionized calcium level with preeclampsia. It also evaluated the association between dietary calcium intake and serum calcium levels. Materials and methods An unmatched case–control study was conducted in Gandhi Memorial, Tikur Anbessa, and Zewditu Memorial Hospitals, all in Addis Ababa, between October to December, 2019. Cases were 42 women with preeclampsia and controls were 42 normotensive women. The medical and obstetric history was gathered using a structured questionnaire and the dietary calcium intake information using a 24-h dietary recall. The serum levels of total serum calcium and ionized (free) calcium were measured using an inductively coupled mass spectrophotometer. Bivariate and multivariate logistic regression and Pearson correlation test were utilized during data analysis. Results In comparison with controls, women with preeclampsia had lower mean (± 1SD) levels of ionized calcium level (1.1 mmol/l ± 0.11), total serum calcium level (1.99 mmol/l ± 0.35) and lower median (IQR) dietary calcium intake (704 mg/24 h,458–1183). The odds of having preeclampsia was almost eight times greater in those participants with low serum ionized calcium level (OR 7.5, 95% CI 2.388–23.608) and three times higher in those with low total serum calcium level (OR 3.0, 95% CI 1.024–9.370). Low dietary calcium intake also showed statistically significant association with preeclampsia (OR 3.4, 95% CI 1.092 -10.723). Serum ionized calcium level and total serum calcium level showed positive correlation of moderate strength (p = 0.004, r = 0.307), but no correlation was found between dietary calcium intake with both forms of serum calcium levels. Conclusion This study showed significant association between low dietary calcium intake and low serum calcium levels with preeclampsia, hence this can be used as a supportive local evidence for the current context-specific recommendation of calcium supplementation in societies with low-dietary calcium consumption in an attempt to prevent preeclampsia, therefore implementation study should be considered in Ethiopia to look for the feasibility of routine supplementation.

scholarly journals Dietary calcium intake, serum calcium level, and their association with preeclampsia in rural North India

2016 ◽  
Vol 41 (3) ◽  
pp. 223 ◽  
Author(s):  
Shashi Kant ◽  
Anant Gupta ◽  
ChandrakantS Pandav ◽  
SanjeevK Gupta ◽  
SanjayK Rai ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Calcium Intake ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Dietary Calcium ◽  
North India ◽  
Dietary Calcium Intake

scholarly journals A cross sectional study to evaluate serum calcium levels among pregnant women and it's association with preeclampsia and delivery outcomes at tertiary care Hospital Bikaner, Rajasthan

2021 ◽  
Vol 10 (5) ◽  
pp. 2026
Author(s):  
Laxmi Poonia ◽  
Swati Kochar ◽  
Shweta Chaudhary ◽  
Priyanka Gaur ◽  
Kirti Solanki
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Control Group ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Background: Hypertensive disorders of pregnancy, including preeclampsia complicates about 10% of pregnancies worldwide. Preeclampsia is one of the major cause of maternal and perinatal morbidity and mortality worldwide. According to the National Health Portal of India, the incidence of preeclampsia is reported to be about 8-10% among pregnant women. The present study was aimed to compare mean serum calcium levels in preeclamptic and normotensive pregnant women at third trimester of gestation and assess relationship between maternal serum calcium levels, severity of disease and overall maternal and perinatal outcome.Methods: This was a cross sectional study conducted on 200 females divided into two groups (i.e. Study and Control Group) from 1st November 2019 to 31st October 2020. Informed consent was obtained for subjecting. Detailed history and clinical examination were performed. Serum calcium level was measured in both groups by spectrophotometric method.Results: Mean serum calcium level in study group (preeclamptic) was 7.84+0.74mg/dl while in control group (normotensive) mean serum calcium level was 9.68+0.97mg/dl. Serum calcium level was significantly lower in preeclamptic women than normotensive pregnant women (p<0.001).Serum calcium showed significant negative correlation with systolic and diastolic blood pressure.Conclusions: This study concludes that hypocalcaemia may have a role in aetiology of preeclampsia and adverse maternal and perinatal outcome. Thus intake of calcium supplements may help in reduction of incidence of preeclampsia especially in a population of a developing country. 

Dietary Calcium Intake and Associated Factors Among Pregnant Women in Loma District, South West Ethiopia, 2020 

2021 ◽  
Author(s):  
Adisu Hailu Tofu ◽  
Yibeltal Kassa ◽  
Damene Darota Amamo
Keyword(s):  
Pregnant Women ◽  
Calcium Intake ◽  
Urban Areas ◽  
Associated Factors ◽  
Statistical Significance ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Nutritional Counseling ◽  
South West ◽  
South West Ethiopia

Abstract Background: Low dietary calcium intakes could cause harmful effects to the pregnant woman by influencing pregnancy outcome. Adequate intake of dietary calcium during pregnancy reduces the risk of complications and aids in improved birth outcome. Many researchers focus on urban areas to address the issue and our study was focused on rural community. Hence the study is aimed at assessing dietary calcium intake in rural communities.Objective: To assess the dietary calcium intakes and associated factors among pregnant women in Loma, south west Ethiopia from May to July, 2019Methods: -A community based cross-sectional study was conducted in Loma district, Dawuro zone, southwest Ethiopia. Data were collected from 398 pregnant women after random selection from nine kebeles. Simple random sampling technique was employed to select study subjects. Socio-economic and demographic, and health related data was collected using structured, interviewer administered, and pre tested questionnaire. The 24 hr dietary recall was used for three different days with seven days interval as per the recommendation. When dietary data is collected, often it was converted into nutrients, especially the calcium intake by using Ethiopian food composition table. Collected data was checked for completeness, and entered in to Epi Data version 3.02 for data clearance and exported to SPSS version 20 for analysis. AOR with 95% C.I results of multivariate logistic regression was used to assess the statistical significance of associations between independent and dependent variables. The level of statistical significance was declared at p <0.05.Result: The median calcium intake was 543mg per day. From 398 participants, 265(66.6%) were at risk of inadequate intake of calcium. Greater than half 249 (62.6%) respondents had practiced avoiding calcium rich food during their pregnancy. The finding of this study identified that nutritional counseling have strong statistical association with dietary calcium intake of mothers during pregnancy. The chance of dietary calcium intakes during pregnancy who were received nutritional counseling 2.4 times higher than those who were not received nutritional counseling (AOR=2.432 95% CI: 1.072-5.517).Conclusion and recommendation: From the present study, it can be concluded that, majority of pregnant mothers 265(66.6%) had a poor dietary calcium intakes during their pregnancy. It is recommended that consumption of enough calcium and dairy products should be included and emphasized in the nutrition education component of maternal health programs.

scholarly journals Calcium Intake and Serum Calcium Level in Relation to the Risk of Ischemic Stroke: Findings from the REGARDS Study

2019 ◽  
Vol 21 (3) ◽  
pp. 312-323 ◽  
Author(s):  
Daniel T. Dibaba ◽  
Pengcheng Xun ◽  
Alyce D. Fly ◽  
Aurelian Bidulescu ◽  
Cari L. Tsinovoi ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Serum Calcium ◽  
Calcium Intake ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Regards Study

scholarly journals Serum calcium level is associated with metabolic syndrome in the general population: FIN-D2D study

2011 ◽  
Vol 165 (3) ◽  
pp. 429-434 ◽  
Author(s):  
J Saltevo ◽  
Leo Niskanen ◽  
Hannu Kautiainen ◽  
Jorma Teittinen ◽  
Heikki Oksa ◽  
...  
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Serum Calcium ◽  
Calcium Intake ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Hdl Cholesterol ◽  
Vitamin D Intake ◽  
Study Population

BackgroundThe aim of this cross-sectional study was to examine the association between serum calcium and the components of metabolic syndrome (MetS).MethodsAs a part of the national prevention program of diabetes in Finland (FIN-D2D), a randomly selected study population of 4500 middle-aged men and women were recruited from three central hospital district areas. Anthropometric measurements were performed by a trained nurse. An oral glucose tolerance test was performed and serum calcium and lipids were measured. We assessed current medications, physical activity, smoking, alcohol consumption, calcium intake, and vitamin D intake. The MetS was defined according to the criteria of the updated National Education Program. The study population consisted of 2896 individuals: 1396 men (62% of invited individuals) and 1500 women (66.7% of invited individuals).ResultsThe mean age was 60.3±8.3 years in men and 59.8±8.5 years in women. The prevalence of MetS was 50.7% in women and 55.8% in men. The prevalence of MetS and its components, except high-density lipoprotein (HDL)-cholesterol, increased linearly with increasing serum calcium (P<0.001), even after adjustment for age, physical activity, alcohol, vitamin D intake, calcium intake, and smoking. The threshold value for serum calcium for MetS was 2.50 mmol/l in this population. The association of MetS with total serum calcium was similar even after exclusion of patients treated with hypertensive drugs. The drug treatments for hypertension, dyslipidemia, and diabetes increased in a similar pattern.ConclusionsSerum calcium level is associated with MetS and its components, except HDL-cholesterol.

scholarly journals Dietary Calcium Intake and Associated Factors among Pregnant Women in Southern Benin in 2014

2015 ◽  
Vol 06 (11) ◽  
pp. 945-954 ◽  
Author(s):  
Victoire Damienne Agueh ◽  
Madeleine Flore Tugoué ◽  
Charles Sossa ◽  
Clémence Métonnou ◽  
Colette Azandjemè ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Calcium Intake ◽  
Associated Factors ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Southern Benin

Evaluation of Serum Calcium Levels in Pre-eclampsia

2018 ◽  
Vol 30 (2) ◽  
pp. 57-60
Author(s):  
Heera Lal Roy ◽  
Susmita Nargis ◽  
Md Mahbubur Rahman ◽  
Mohammad Shahadat Hossain ◽  
Md Ruhul Amin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Gestational Age ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Colorimetric Method ◽  
Medical Complication ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
The Mean

Pre-eclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum calcium level are found associated with elevated blood pressure in preeclampsia. To evaluate serum calcium level in pre-eclamptic women. This cross sectional study was carried out in among 50 preeclamptic patients, aged 20 to 40 years, and gestational age ranges from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria. Serum calcium was measured by Colorimetric method. The mean age and mean gestational age of pre-eclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean body mass indexes of the test patients were significantly different from those of normotensive pregnant women (p<0.001). The mean serum calcium level was 7.27 ± 3.01 mg/dl in pre-eclampsia and 7.25 ± 2.59 mg/dl in normal pregnant women; did not differ significantly between the subjects of pre-eclampsia and normal pregnant women (p=0.963). Serum calcium has no association in occurrence of preeclampsia.Medicine Today 2018 Vol.30(2): 57-60

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