scholarly journals Coronary Artery Thrombosis: Is High Serum Homocysteine Level a Culprit?

2014 ◽  
Vol 11 (1) ◽  
pp. 49-52
Author(s):  
Laxman Dubey ◽  
Sogunuru Guruprasad ◽  
Rabindra Bhattacharya ◽  
Gangapatnam Subramanyam
Keyword(s):  
Coronary Artery ◽  
Arterial Thrombosis ◽  
Biochemical Analysis ◽  
Homocysteine Level ◽  
Intravenous Thrombolysis ◽  
High Serum ◽  
Artery Thrombosis ◽  
Serum Homocysteine ◽  
Coronary Artery Thrombosis ◽  
Artery Disease

Hyperhomocysteinemia is a risk factor of coronary artery disease associated to arterial thrombosis. We report a case in which coronary angiography showed full of thrombus causing total obstruction of the left anterior descending artery. Patient was managed successfully with intravenous thrombolysis. Biochemical analysis revealed a high serum homocysteine level. DOI: http://dx.doi.org/10.3126/njh.v11i1.10982   Nepalese Heart Journal 2014;11(1): 49-52

scholarly journals Effect of Serum Homocysteine on Coronary Artery Disease in Younger and Older Ischaemic Heart Disease Patients

2016 ◽  
Vol 8 (2) ◽  
pp. 138-142
Author(s):  
Kazi Nazrul Islam ◽  
Abdul Wadud Chowdhury ◽  
Azizul Hasan Khondoker ◽  
Md Serajul Haque ◽  
KMN Sabah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Homocysteine Level ◽  
Serum Homocysteine ◽  
Artery Disease

Background: Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis. But the probable role of Hyperhomocysteinemia in Premature Coronary Artery Disease (CAD) is not well studied. The aim of this study was to assess the role of serum homocysteine on angiographically documented CAD in younger and older ischaemic heart disease (IHD) patients.Methods: Total 120 patients with IHD admitted in the Department of Cardiology, Dhaka Medical College Hospital for CAG were selected by purposive sampling method and divided into two groups. 60 patients in Group-I, d” 40 years of age (Younger); 60 patients in Group-II, >40 years of age (Older). Homocysteine was measured in all patients and other demographical and clinical data were collected. Homocysteine level was correlated with the presence and severity of CAD.Results: Smoking, positive family history of IHD, dyslipidaemia and hyper homocysteinemia were important risk factors in younger IHD patients. Whereas, hypertension, diabetes mellitus and dyslipidaemia were important cardiovascular risk factors in older age group. Obesity was not an important risk factors as evidenced by mean BMI. Serum homocysteine was not well related to presence of CAD or extent of CAD in older IHD patients. However in younger patients hyperhomocysteinemia was related to both presence and severity of CAD.Conclusion: In younger IHD patients hyperhomocysteinemia is an important cardiovascular risk factor. But in older patients it loses its significance. So serum homocysteine level should be screened routinely in younger IHD patients.Cardiovasc. j. 2016; 8(2): 138-142

scholarly journals CLINICAL CORRELATION OF SERUM HOMOCYSTEINE LEVEL WITH LIPID PROFILE IN CORONARY ARTERY DISEASE PATIENTS

2015 ◽  
Vol 4 (32) ◽  
pp. 5444-5451
Author(s):  
Shalini Jain ◽  
Pushpraj Singh Baghel ◽  
Neeraj Jain ◽  
Avdhesh Pratap Singh Kushwaha ◽  
Shashi Prabha Tomar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Homocysteine Level ◽  
Clinical Correlation ◽  
Serum Homocysteine ◽  
Artery Disease
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