scholarly journals CLINICAL CORRELATION OF SERUM HOMOCYSTEINE LEVEL WITH LIPID PROFILE IN CORONARY ARTERY DISEASE PATIENTS

2015 ◽  
Vol 4 (32) ◽  
pp. 5444-5451
Author(s):  
Shalini Jain ◽  
Pushpraj Singh Baghel ◽  
Neeraj Jain ◽  
Avdhesh Pratap Singh Kushwaha ◽  
Shashi Prabha Tomar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Homocysteine Level ◽  
Clinical Correlation ◽  
Serum Homocysteine ◽  
Artery Disease

scholarly journals Effect of Serum Homocysteine on Coronary Artery Disease in Younger and Older Ischaemic Heart Disease Patients

2016 ◽  
Vol 8 (2) ◽  
pp. 138-142
Author(s):  
Kazi Nazrul Islam ◽  
Abdul Wadud Chowdhury ◽  
Azizul Hasan Khondoker ◽  
Md Serajul Haque ◽  
KMN Sabah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Homocysteine Level ◽  
Serum Homocysteine ◽  
Artery Disease

Background: Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis. But the probable role of Hyperhomocysteinemia in Premature Coronary Artery Disease (CAD) is not well studied. The aim of this study was to assess the role of serum homocysteine on angiographically documented CAD in younger and older ischaemic heart disease (IHD) patients.Methods: Total 120 patients with IHD admitted in the Department of Cardiology, Dhaka Medical College Hospital for CAG were selected by purposive sampling method and divided into two groups. 60 patients in Group-I, d” 40 years of age (Younger); 60 patients in Group-II, >40 years of age (Older). Homocysteine was measured in all patients and other demographical and clinical data were collected. Homocysteine level was correlated with the presence and severity of CAD.Results: Smoking, positive family history of IHD, dyslipidaemia and hyper homocysteinemia were important risk factors in younger IHD patients. Whereas, hypertension, diabetes mellitus and dyslipidaemia were important cardiovascular risk factors in older age group. Obesity was not an important risk factors as evidenced by mean BMI. Serum homocysteine was not well related to presence of CAD or extent of CAD in older IHD patients. However in younger patients hyperhomocysteinemia was related to both presence and severity of CAD.Conclusion: In younger IHD patients hyperhomocysteinemia is an important cardiovascular risk factor. But in older patients it loses its significance. So serum homocysteine level should be screened routinely in younger IHD patients.Cardiovasc. j. 2016; 8(2): 138-142

Serum Interleukin-6 and Lipid Atherogenic Index Risk Ratios as Interpreters of Cardiac Disease in Obese and Non Obese Male Patients of Coronary Artery Disease

2021 ◽  
Vol 15 (6) ◽  
pp. 1203-1205
Author(s):  
S. Naz ◽  
M. Raza ◽  
A. Akbar ◽  
A. N. Zaidi ◽  
S. Khaliq ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Interleukin 6 ◽  
Significant Positive Correlation ◽  
Atherogenic Index ◽  
Positive Correlation ◽  
Male Patients ◽  
Artery Disease ◽  
Obese Male

Aim: To evaluate serum Interleukin-6, and lipids as predictors of cardiovascular diseases (CVD) in obese and non obese male patients of coronary artery disease (CAD). Methodology: It was cross-sectional comparative study. Serum Interleukin-6 and lipid profile was determined in non diabetic, non smoker and non hypertensive age matched obese and non obese male patients of CAD and healthy subjects. Sixty male subjects were divided equally into groups. Group 1, healthy controls (n=20), group 2, non obese male patients with CAD (n=20) and group 3 included Obese male patients with CAD (n=20). The serum was assayed for lipid profile and interleukin-6 . Results: Age matched healthy and patients were non diabetics, non hypertensive and non smoker with altered lipid profile in obese and non obese male patients with coronary artery disease. Patients have high serum cholesterol, low density cholesterol(LDL-C), Triglyceride(TG,) very low density lipoprotein(VLDL) and interleukin-6. The High density lipoprotein was lowered in both obese and non obese male patients with CAD. Significant positive correlation was observed in CAD group of IL-6 with TC (rho= 0.405, p= 0.009*) , with TG (rho= 0.639, p= 0.000*) ,with LDL (rho= 0.398, p= 0.002*), with VLDL (rho= 0.315, p= 0.014*). Significant negative correlation was observed in CAD group of IL-6 with HDL (rho= -0.565, p= 0.000*) Significant positive correlation was observed in CAD group of IL-6 .Significant positive correlation of IL-6 was observed with AI (rho= 0.602, p= 0.000*). Conclusion: Dyslipidemia, Raised interleukin-6 and strong positive correlation of Atherogenic index with IL-6 are independent risk factors for CVD; using Atherogenic risk ratios as a screening tool for the estimation of CVD risk is useful in patients with CAD. Keywords: Lipid profile, serum interleukin-6,Atherogenic index,coronary artery disease.

scholarly journals Serum Copper with Coronary Artery Disease in Male and its Relation with Lipid Profile

1970 ◽  
pp. 7-9
Author(s):  
Sifat Jubaira ◽  
Forhadul Haque Mollah ◽  
Tahrim Mehdi ◽  
M Iqbal Arslan
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Acute Myocardial Infarction ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Serum Copper ◽  
Copper Level ◽  
Serum Copper Level ◽  
Artery Disease

The study was designed to explore serum copper as a risk factor for coronary artery disease (CAD). In this case-control study 30 healthy controls and 60 diagnosed cases of acute myocardial infarction (AMI) were enrolled. Serum copper concentration and serum lipid profile were measured in all study subjects. Serum copper level was significantly higher in AMI as compared to controls. The concentrations of serum TC, TG, LDL-C level were found to be significantly higher in cases as compared to controls. The concentration serum HDL-C was found to be significantly lower in cases as compared to controls. CAD leads to raised serum copper level and it has positive correlation with TC, TG and LDL-C but negative correlation with HDL-C in males.Keywords: Coronary artery disease; serum copper; acute myocardial infarction; total cholesterol; triglyceride; low density lipoprotein cholesterol. DOI: 10.3329/bjpp.v24i1.5730Bangladesh J Physiol Pharmacol 2008; 24(1&2) : 7-9

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