scholarly journals TCTAP A-078 Serum Homocysteine Level Influences on Risk Factor and Severity of Coronary Artery Disease in Young Patients

2014 ◽  
Vol 63 (12) ◽  
pp. S22
Author(s):  
Zhu Hang ◽  
Xue Hao ◽  
Zhang Ming ◽  
Chen Si ◽  
Wang Guang yi
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Homocysteine Level ◽  
Young Patients ◽  
Serum Homocysteine ◽  
Artery Disease

scholarly journals Effect of Serum Homocysteine on Coronary Artery Disease in Younger and Older Ischaemic Heart Disease Patients

2016 ◽  
Vol 8 (2) ◽  
pp. 138-142
Author(s):  
Kazi Nazrul Islam ◽  
Abdul Wadud Chowdhury ◽  
Azizul Hasan Khondoker ◽  
Md Serajul Haque ◽  
KMN Sabah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Homocysteine Level ◽  
Serum Homocysteine ◽  
Artery Disease

Background: Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis. But the probable role of Hyperhomocysteinemia in Premature Coronary Artery Disease (CAD) is not well studied. The aim of this study was to assess the role of serum homocysteine on angiographically documented CAD in younger and older ischaemic heart disease (IHD) patients.Methods: Total 120 patients with IHD admitted in the Department of Cardiology, Dhaka Medical College Hospital for CAG were selected by purposive sampling method and divided into two groups. 60 patients in Group-I, d” 40 years of age (Younger); 60 patients in Group-II, >40 years of age (Older). Homocysteine was measured in all patients and other demographical and clinical data were collected. Homocysteine level was correlated with the presence and severity of CAD.Results: Smoking, positive family history of IHD, dyslipidaemia and hyper homocysteinemia were important risk factors in younger IHD patients. Whereas, hypertension, diabetes mellitus and dyslipidaemia were important cardiovascular risk factors in older age group. Obesity was not an important risk factors as evidenced by mean BMI. Serum homocysteine was not well related to presence of CAD or extent of CAD in older IHD patients. However in younger patients hyperhomocysteinemia was related to both presence and severity of CAD.Conclusion: In younger IHD patients hyperhomocysteinemia is an important cardiovascular risk factor. But in older patients it loses its significance. So serum homocysteine level should be screened routinely in younger IHD patients.Cardiovasc. j. 2016; 8(2): 138-142

scholarly journals Homocysteine: Chemistry, metabolism and roles in pathophysiology processes

2003 ◽  
Vol 22 (2) ◽  
pp. 127-140 ◽  
Author(s):  
Dusko Mirkovic ◽  
Nada Majkic-Singh ◽  
Svetlana Ignjatovic
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Chemical Structure ◽  
Independent Risk Factor ◽  
Homocysteine Level ◽  
Premature Coronary Artery Disease ◽  
Severe Mental Retardation ◽  
Vascular Changes ◽  
Artery Disease

In 1962, 30 years after chemical structure discovery of homocysteine, Carson and Neil reported work in which they described cases of two young people with severe mental retardation and high homocysteinuria. In 1975 McCully emphasized the association between homocysteinuria and thrombus-occlusive vascular changes. Period 1991-98, is the time of very extensive comparative studies, with aim of establishing links between premature coronary artery disease and high homocysteine level in plasma. These results in a whole show that biochemical findings of a mild increase of homocysteine plasma levels in span of 15-45 mmol/L, are independent risk factor for premature coronary artery disease appearance. So far mechanism of direct homociysteine uninfluenced on endothelial vascular vessels cells, or influence of any other factor, which play role in methionine-homocysteine-cysteine path (vitamins B6, B12, folic acid) are not strictly elucidated.

scholarly journals Cardiovascular risk factor control is insufficient in young patients with coronary artery disease

2016 ◽  
pp. 219 ◽  
Author(s):  
Morten Christiansen ◽  
Jesper Møller Jensen ◽  
Anders Brondberg ◽  
Hans Erik Bøtker ◽  
Henrik Jensen
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factor ◽  
Young Patients ◽  
Risk Factor Control ◽  
Artery Disease

scholarly journals CLINICAL CORRELATION OF SERUM HOMOCYSTEINE LEVEL WITH LIPID PROFILE IN CORONARY ARTERY DISEASE PATIENTS

2015 ◽  
Vol 4 (32) ◽  
pp. 5444-5451
Author(s):  
Shalini Jain ◽  
Pushpraj Singh Baghel ◽  
Neeraj Jain ◽  
Avdhesh Pratap Singh Kushwaha ◽  
Shashi Prabha Tomar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lipid Profile ◽  
Homocysteine Level ◽  
Clinical Correlation ◽  
Serum Homocysteine ◽  
Artery Disease
Sign in / Sign up

Export Citation Format

Share Document