Use of Bladder diary as diagnostic and therapeutic tool for Overactive Bladder

Aims: To evaluate use of diary for teaching patient with overactive bladder and see its therapeutic effects in terms of reduction in their symptoms Methods: A single-blind randomized clinical trial, regarding “Effects of Bladder Training and behavioral intervention in Female Patients with Over active Bladder syndrome, attending Urogynecology clinic at The Aga Khan University Hospital Karachi, Pakistan: A Randomized Controlled Trial (OAB) trial” We here present the additional conclusions drawn from results of ARM-1.Arm-1 patients were managed by behavioral intervention only and were asked to fill 7 days diary in 12 weeks .By using WHO software a minimum of 114 women needed to meet the study objectives. We recruited 50 women in each group (150 totals) as there was a possibility of drop out.We calculated the mean difference in fluid intake and reduction in urinary frequency, urgency, nocturia before and after educating the patient using the paired-T Test. Results: A total of 47 women completed follow up visits for overactive bladder treatment ARM-A. (Mean ± SD) Mean fluid intake on first diary was 2392.9 ml while on last diary fluid intake was reduced to 177.1ml with mean fluid intake difference of 621.8ml+622.2(p<0.00).The mean reduction in frequency of micturition during day and nocturia was 2.9+2.7(P<0.00) and 0.59+ 0.99(p<0.00) respectively. The mean decrease in urgency score and reduction in leak accident was 1.19+1.2(p<0.00) and 0.9+0.95(p<0.00) respectively. Conclusions: The bladder diary for women with OAB has both diagnostic and therapeutic effect. In developing countries it is an easy least expensive but time consuming method of treatment for simple cases of OAB.

Download Full-text

Therapeutic Effects of Hab Shabyar on Open-Angle Glaucoma: A Double-Blinded, Randomized, Placebo-Controlled Trial

10.31661/gmj.v0i0.1218 ◽

2019 ◽

Vol 8 ◽

pp. 1218

Author(s):

Ebrahim Khalil BaniHabib ◽

Ali Mostafai ◽

Seyyed Mohammad Bagher Fazljou ◽

Ghadir Mohammdi

Keyword(s):

Placebo Group ◽

Intraocular Pressure ◽

Open Angle Glaucoma ◽

Controlled Trial ◽

Intervention Group ◽

Therapeutic Effects ◽

Open Angle ◽

The Mean ◽

The Right ◽

Double Blinded

Background: Open-angle glaucoma (OAG) is one of the leading causes of blindness worldwide. This study evaluates the therapeutic effects of hab shabyar in patients with open-angle glaucoma. Materials and Methods: In this clinical randomized controlled trial, 50 patients with OAG were randomized into two groups. The intervention group was received a drop of timolol plus 500 mg of hab shabyar every 12 hours. The placebo group was received a drop of timolol every 12 hours plus 500 mg of wheat germ as a placebo. The intraocular pressure in patients with OAG was measured in each group and compared at before the intervention (t1), one month (t2), and two months (t3) after the intervention. Results: The mean decrease in intraocular pressure for the right eye at three times in the intervention group was statistically significant, but the mean decrease in the placebo group was not significant. Similar results were obtained for the left eye at t1 when compared to t3. The patients in the intervention group expressed more satisfaction than the patients in the placebo group (P≤0.001). Conclusion: Our study demonstrated that consumption of timolol plus hab shabyar instead of consuming of timolol alone was probably more effective for reducing intraocular pressure in patients with OAG.[GMJ.2019;In press:e1218]

Download Full-text

The effectiveness of emotional freedom techniques (EFT) on depression of postmenopausal women: a randomized controlled trial

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2020-0245 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Asieh Mehdipour ◽

Parvin Abedi ◽

Somayeh Ansari ◽

Maryam Dastoorpoor

Keyword(s):

Randomized Controlled Trial ◽

Postmenopausal Women ◽

Controlled Trial ◽

Intervention Group ◽

Control Group ◽

Randomized Controlled ◽

Moderate Depression ◽

Before And After ◽

The Mean ◽

And Control

Abstract Objectives Postmenopausal women are at greater risk of depression. Depression may negatively affect the quality of life of women. An emotional freedom technique (EFT) is an evidence-based therapy combining cognitive and exposure components with acupressure. This study aimed to evaluate the effect of EFT on depression in postmenopausal women. Methods This was a randomized controlled trial in which 88 women with mild to moderate depression recruited from a menopausal clinic in Ahvaz, Iran, and randomly assigned into two groups of EFT (n=44) and control for sham therapy (n=44). Women in the EFT group received two sessions of training and asked to continue EFT for 8 weeks, one time per day. The Beck Depression Inventory (BDI2) completed by women before and after the intervention. The control group received training on sham acupressure points similar to the intervention group. Data collected using a demographic and BDI2. Women requested to complete the BDI2 before and after the intervention. The independent t-test, chi-square, and ANCOVA were used to analyze data. Results The mean depression score in the intervention group reduced from 20.93 ± 4.6 to 10.96 ± 4.38 in comparison to the control group that reduced from 19.18 ± 2.79 to 17.01 ± 6.05 after intervention (p=0.001). After the 8 week intervention, the frequency of moderate depression decreased from 56.8 to 9.35% in the intervention and from 50 to 29.5% in the control group. In total, 63.4 and 34.15% in the intervention and control groups were free of depression respectively after the intervention (p<0.001). Conclusions The results of this study showed that using EFT for 8 weeks could significantly reduce the mean score of depression in postmenopausal women. Using this method in public health centers for postmenopausal women is recommended.

Download Full-text

Comparative Effects of Portable and Stationary Traction in the Management of Mechanical Neck Disorders

Rehabilitation Process and Outcome ◽

10.4137/rpo.s24889 ◽

2015 ◽

Vol 4 ◽

pp. RPO.S24889

Author(s):

Ajediran I. Bello ◽

Jacquelyn A. Crabbe ◽

Emmanuel Bonney

Keyword(s):

Treatment Outcome ◽

Treatment Outcomes ◽

Therapeutic Effects ◽

Neck Flexion ◽

Pain Level ◽

Before And After ◽

Neck Disorders ◽

The Mean ◽

Traction Group ◽

Paired T Test

Objective The purpose of this study was to compare the therapeutic effects of portable and stationary tractions on treatment outcomes in patients with mechanical neck disorders (MNDs). Methods Forty-one participants with MNDs were randomly assigned to either portable traction or stationary traction. Participants' pain level, activity limitation, disability, and neck range of motion were measured before and after 6 weeks of intervention. Inferential statistics for comparing the treatment outcome involved paired t-test and two-way analysis of variance at P < 0.05. Results The mean age of participants was 47.3 ± 10.5 years. After intervention, there were significant improvements in both groups. However, the portable traction group had significantly higher score on neck flexion than the stationary traction group at baseline (portable: 27.1 ± 6.0, stationary: 22.1 ± 6.8; P = 0.009) and after intervention ( F-ratio = 15.0; P = 0.001). Conclusion Inclusion of both portable and stationary tractions to usual physiotherapy provided comparable treatment outcomes in patients with MNDs.

Download Full-text

Assessment of the Efficacy of Photodynamic Therapy in Patients with Chronic Central Serous Chorioretinopathy

Czech and Slovak Ophthalmology ◽

10.31348/2019/6/2 ◽

2020 ◽

Vol 75 (6) ◽

pp. 298-308

Author(s):

Kateřina Manethová ◽

Jan Ernest ◽

Michal Hrevuš ◽

Naďa Jirásková

Keyword(s):

Photodynamic Therapy ◽

Central Serous Chorioretinopathy ◽

Functional Results ◽

University Hospital ◽

Prospective Clinical Study ◽

Chronic Central Serous Chorioretinopathy ◽

Chronic Form ◽

Before And After ◽

The Mean

Purpose: The aim of this prospective clinical study was to evaluate the anatomical and functional results of the treatment of 54 eyes with chronic form of central serous chorioretinopathy (CSC) using photodynamic therapy in a reduced (half) verteporfin (HD-PDT) dosing regimen. Materials and Methods: Our prospective study included 54 eyes of 52 patients (40 males, 12 females) at an average age of 50.1 years (median 49.5, range 30–75 years) treated at the Ophthalmology Clinic of the First Faculty of Medicine and Military University Hospital in Prague from January 2012 to January 2018 for chronic form of CSC with a minimum disease duration of 3 months. In our study, we evaluated the improvement of the best corrected visual acuity (BCVA) and central retinal thickness (CRT) before treatment and at 1, 3, 6 and 12 months after HD-PDT. Results: The mean baseline BCVA was 68.91 ± 10.5 ETDRS letters (median 71; range 35–85) and the mean baseline CRT was 385.6 ± 118.5 µm (median 367, 5 µm; range 245–1000 µm). At the end of the follow-up period, the average BCVA was 79 ± 11 ETDRS letters (median 82; range 38–93). The improvement in BCVA before and after treatment was statistically significant in all measurements (p < 0.0001). The mean CRT at the end of the follow-up period was 263.5 ± 52 µm (median 258.5 µm; range 162–404 µm). The decrease in CRT at all timepoints was statistically significant compared to baseline (p < 0.0001). In our set of patients, at the end of the follow-up period, the retinal finding was improved or stabilized in 50 eyes (92.6 %). In this study, we observed in 2 cases the development of secondary choroidal neovascularization (CNV). Conclusion: HD-PDT is a long-term safe and effective method of treating chronic forms of CSC. However, despite a reduced dose of verteporfin, complications may occur.

Download Full-text

Effects of Acupuncture on the Hypothalamus-Pituitary-Adrenal Axis in Chronic Insomnia Patients: A Study Protocol for a Randomized Controlled Trial

10.21203/rs.2.14637/v1 ◽

2019 ◽

Author(s):

Chengyong Liu ◽

Shiyu Zheng ◽

Wenzhong Wu ◽

Xiaoqiu Wang ◽

Shan Qin ◽

...

Keyword(s):

Chinese Medicine ◽

Traditional Chinese Medicine ◽

Outcome Measures ◽

Controlled Trial ◽

Severity Index ◽

Chronic Insomnia ◽

Secondary Outcome ◽

Therapeutic Effects ◽

Before And After ◽

Fatigue Severity

Abstract Background : Acupuncture, as an important component of traditional Chinese medicine (TCM), has been widely applied in the treatment of chronic insomnia in China，while there is no clinical study related to its therapeutic mechanism. Methods/design : A single-center, single-blind, randomized, placebo-controlled trial will be conducted at Jiangsu Hospital of Traditional Chinese Medicine. A total of 60 patients will be registered.Eligible participantswill be randomly divided into acupuncture group and shamacupuncture group (n = 30 cases in each group). Patients in both groups will be treated once every other day, 3 times per week for 4 weeks.The primary outcome measures are Pittsburgh Sleep Quality Index (PSQI), concentrations of adrenocorticotropic hormone (ATCH), Corticotrophin-releasing hormone (CRH), and cortisol (CORT). Secondary outcome measures are Insomnia Severity Index (ISI) and Fatigue Severity Scale (FSS). Discussion : This study aims to evaluate the therapeutic effects of acupuncture on chronic insomnia by using PSQI, ISI, and FSS. The mechanism of acupuncture on CIPs will be preliminarily discussed by analyzing the changes in concentrations of CRH, ACTH, and CORT before and after treatment.

Download Full-text

Efficacy and tolerability of combined medication of two different antimuscarinics for treatment of adults with idiopathic overactive bladder in whom a single agent antimuscarinic therapy failed

Canadian Urological Association Journal ◽

10.5489/cuaj.269 ◽

2013 ◽

Vol 7 (1-2) ◽

pp. 88 ◽

Cited By ~ 8

Author(s):

Junseok Yi ◽

Seong Jin Jeong ◽

Min Soo Chung ◽

Hongzoo Park ◽

Sang Wook Lee ◽

...

Keyword(s):

Overactive Bladder ◽

Statistical Significance ◽

Single Agent ◽

Clean Intermittent Catheterization ◽

Dosage Escalation ◽

Before And After ◽

The Mean ◽

Combined Medication ◽

Voided Volume ◽

Antimuscarinic Therapy

Objective: Recent studies have investigated a combination of two antimuscarinics for adult neurogenic bladder managed with clean intermittent catheterization or pediatric refractory overactive bladder (OAB). We assessed the efficacy and tolerability of this strategy in adults with idiopathic OAB.Methods: We reviewed 49 patients with idiopathic OAB whoreceived combined antimuscarinic medication. Patients had seriallyreceived different kinds of antimuscarinics as monotherapy, but wished to take combined medication due to a lack of sufficient subjective improvement in urgency, even with dosage escalation. Efficacy was measured by changes of episodes of urgency, daytime voiding, nocturia and mean voided volume before and after the addition of the second antimuscarinic.Results: The mean duration of combined medication was 9.3 months. After adding the second antimuscarinic, urgency per day decreased from 3.8 to 1.9 (p < 0.001) and daytime voiding decreased from 10.4 to 7.4 (p < 0.001). The number of nocturia episodes and the mean voided volume also improved, although therewas no statistical significance. Efficacy did not differ between the 29 cases, with non-selective and non-selective drugs and 20 cases with non-selective and M3 selective drugs. Thirty-three (67.3%) patients reported to have benefited from combined medication. Maximal flow rate and post-void residual volume did not change in either of the sexes. Eleven (22.4%) patients discontinued the combination due to continued ineffectiveness and dry mouth.Conclusion: This retrospective study suggests that combined medication can help adults with refractory idiopathic OAB. Combined medication was tolerated in most of our patients.

Download Full-text

Comparison of the Effect of Inhalation Aromatherapy with 10% and 30% Peppermint Essential Oils on the Severity of Nausea in Abdominal Surgery Patients

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2020/5897465 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Yasin Ahmadi ◽

Jahangir Rezaei ◽

Mansour Rezaei ◽

Alireza Khatony

Keyword(s):

Abdominal Surgery ◽

Essential Oils ◽

Controlled Trial ◽

Control Group ◽

Green Food ◽

Severity Scores ◽

Significant Difference ◽

Before And After ◽

The Mean ◽

And Control

Background. One of the most common surgical complications is nausea. Regarding the contradictory findings on the effect of aromatherapy with peppermint on the severity of nausea, in the present study, we aimed at comparing the effect of aromatherapy with 10% and 30% peppermint essential oils on the severity of nausea in surgical patients. Methods. This single-blind randomized controlled trial was conducted at the surgical ward of Imam Reza Hospital in Kermanshah, Iran. A total of 120 patients undergoing abdominal surgery were randomly divided into three groups of 10% peppermint, 30% peppermint, and control (40 patients in each group) using a random number table. In each of the intervention groups, 0.2 ml of 10% and 30% peppermint essential oil was inhaled. In the control group, the same amount of distilled water colored with green food coloring was inhaled. The severity of nausea was measured by nausea visual analog scale (NVAS) before and 10 minutes after the intervention. Results. In the 10% peppermint group, the mean severity of nausea before the intervention was 52.3 ± 13.7 out of 100, which reduced to 40.5 ± 13.5 after the intervention (p<0.001). In the 30% peppermint group, the mean severity scores of nausea before and after the intervention were 60.2 ± 15.0 and 39.7 ± 12.4, respectively (p<0.001). In the control group, the mean severity scores of nausea before and after the intervention was not statistically significant. There was no significant difference between the two intervention groups in terms of the mean severity of nausea after the intervention. Conclusions. It can be concluded that 10% and 30% peppermint essential oils are equally effective on the severity of nausea.

Download Full-text

CHANGE OF SOME INDICATORS OF EYES BEFORE AND AFTER SURGICAL TREATMENT PHACO CATARACT SENIORS IN HUE UNIVERSITY HOSPITAL

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2014.6.11 ◽

2015 ◽

pp. 81-85

Author(s):

Thi Dieu Tram Phan ◽

Van Nam Phan

Keyword(s):

Anterior Chamber Depth ◽

University Hospital ◽

Radius Of Curvature ◽

Postoperative Astigmatism ◽

First Choice ◽

Before And After ◽

Corneal Radius ◽

The Mean ◽

Phacoemulsification Cataract Surgery ◽

Cataract Patients

Objective: Phacoemulsification cataract surgery is the method applyied commonly and the first choice of Ophthalmologist. Materials and Method: We study comprised 49 eyes of 42 cataract patients for Phacoemulsification at Hue Hospital University from 5/2013 to 4/2014 with within 3 months after surgery. Result: 3 months after surgery, the visual acuity ≤ 4/10 accounted for 75,5%, corrected vision ≥ 4/10 accounted for 95,9%. The mean postoperative astigmatism was 1,02D ± 0,58, stable and does not change much compared to before surgery. The mean intraocular pressure (IOP) increased to 10,51mmHg ± 1,77 at 3 months postoperatively,the IOP was 3,9mmHg lower at 3 months than preoperative. Anterior chamber depth (ACD) increased by 1,0mm deeper than before surgery. Corneal refractive power increased 0,43D. Corneal radius of curvature decreased 0,11mm by 3 month postoperatively. Key words: Cataract, Phacoemulsification.

Download Full-text

The Effect of the Web-Based Communication between a Nurse and a Family Member on the Perceived Stress of the Family Member of Patients with Suspected or Confirmed COVID-19: A Parallel Randomized Clinical Trial

Clinical Nursing Research ◽

10.1177/10547738211017688 ◽

2021 ◽

pp. 105477382110176

Author(s):

Esmail Shariati ◽

Ali Dadgari ◽

Seyedeh Solmaz Talebi ◽

Gholam Reza Mahmoodi Shan ◽

Hossein Ebrahimi

Keyword(s):

Family Member ◽

Perceived Stress ◽

Controlled Trial ◽

Intervention Group ◽

Control Group ◽

Web Based ◽

Randomized Controlled ◽

The Family ◽

Before And After ◽

The Mean

The aim of this study was to identify the effect of web-based communication between a nurse and a family member of a patient with COVID-19 on his/her perceived stress. In this multicenter parallel randomized controlled trial, 67 family members of COVID-19 patients admitted to the Intensive Care Unit (ICU) were investigated. In the intervention group, web-based communication was performed for four consecutive days for 10 to 15 minutes. The Perceived Stress Scale (PSS-14) were completed in both groups before and after the intervention. Mean and standard deviation of perceived stress scores in the two groups were not significantly different ( p = 0.26) before the intervention; however, after the intervention, the mean PSS-14 in the intervention group was significantly lower than that of the control group ( p < 0.001). Due to the need to follow the physical and social distancing to protect against Coronavirus disease, the use of web-based communication recommended in future studies.

Download Full-text

The Effects of Ketamin-Midazolam and Ketamin-Propofol on Bispectral Index Score as Sedatives During Bone Marrow Puncture Procedure Among Pediatrics

Journal of Anesthesiology and Clinical Research ◽

10.37275/jacr.v2i1.143 ◽

2021 ◽

Vol 2 (1) ◽

pp. 115-134

Author(s):

Aldiar ◽

Fredi Heru Irwanto ◽

Andi Miarta ◽

Irfannuddin

Keyword(s):

Bone Marrow ◽

Controlled Trial ◽

Invasive Procedure ◽

Combination Group ◽

Exclusion Criteria ◽

Pediatric Leukemia ◽

Significant Difference ◽

Optimal Value ◽

Before And After ◽

The Mean

Background: Bone Marrow Puncture (BMP) is an invasive procedure associated with pain and anxiety. The ketamine-midazolam and the ketamine-propofol is an effectivecombination with minimal side effects. This study of the study aims to compare the effect of the combination of ketamine-midazolam and ketamine- propofol on sedation depth based on BIS in pediatric leukemia patients undergoing BMP. Methods: This study was a randomized controlled trial that was done single-blinded. The population was all pediatric patients diagnosed with leukemia who underwent BMP at RSMH and performed sedation. The research sample is the population that fulfill the inclusion and exclusion criteria. The sample size for each group was 25, with 50 Subjects in total. Sampling was done by block randomization. Results: This study found no differences in sex, age, and body weight between the two groups ([p=1.000], [p=0.845], and [p=0.147], respectively). In this study, there was no difference in mean MAP (p=0.592), oxygen saturation (p=0.164), heart rate (p=0.098), and respiratory rate (p=0.252) before intervention between the two groups. BIS value of the two groups had significant difference before and after the intervention where the two groups could reduce BIS to reach the optimal value of sedation <60 (p <0.05) There was no difference in BIS before intervention in the two groups (p=0.385). In this study, it was found that hypersalivation occurred more frequently in the ketamine-midazolam combination group. Conclusion: The combination of ketamine-midazolam and ketamine-propofol was equally good for sedation as indicated by a decrease in the mean BIS in patients undergoing BMP.

Download Full-text