scholarly journals Female genital tract tuberculosis in Tribhuvan University Teaching Hospital: A retrospective one year histopathological study

1970 ◽  
Vol 2 (2) ◽  
pp. 29-34
Author(s):  
Abhimanyu Jha ◽  
Gita Sayami ◽  
Ram Adhikari ◽  
Roona Jha ◽  
Rashmi Chaudhari
Keyword(s):  
Teaching Hospital ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Clinical Findings ◽  
University Teaching ◽  
Histopathological Study ◽  
Fallopian Tubes ◽  
Peritoneal Biopsy ◽  
One Year ◽  
Female Genital

Aim: To determine frequency of female genital tract (FGT) tuberculosis (TB) in the gynecological biopsies received in the Department of Histopathology of Tribhuvan University Teaching Hospital. Methods: This is a retrospective study conducted in the Department of Pathology of Tribhuvan University Teaching Hospital. Histopathology records of one year (14th April 2006 to 13th April 2007) were retrieved and searched for the cases of female genital tract TB. Relevant histopathological findings and clinical data were recorded and analyzed. Results: We analyzed 5696 histopathological cases during one year period for FGT tuberculosis. There were 1565 cases of gynecological biopsy and 9 cases were diagnosed as FGT tuberculosis based on histopathological and clinical findings. Ovarian tuberculosis was seen in three cases, bilateral fallopian tubes were involved in 2 cases and endometrial tuberculosis was diagnosed in 2 cases. 3 cases of omental biopsy and 1 case of peritoneal biopsy showed tubercular granulomas. Conclusion: FGT tuberculosis was usually seen in age 16-28 years and constituted 0.57% of total gynecological cases and 0.15% of total biopsies. Fallopian tubes, ovaries and endometrium were affected with the involvement of peritoneum or omentum, common event being tubercular endosalpingitis. Histopathology in association with clinical findings still remains gold standard for the diagnosis of FGT tuberculosis in our country despite advancement in diagnostic modalities; however, incidental histological detection in clinically unanticipated cases is not an uncommon event. Key Words: Female genital tract TB, histopathology, clinical findings.   doi:10.3126/njog.v2i2.1452 N. J. Obstet. Gynaecol 2007 Nov-Dec; 2 (2): 29 - 34

scholarly journals An Over-View of Tuberculosis of Female Genital Tract With Reference To Experience in a Medical College in Rural Set-Up in West Bengal: A Retrospective Two Year Study

2012 ◽  
Vol 11 (3) ◽  
pp. 185-190
Author(s):  
J Datta ◽  
TK Ghosh ◽  
S Ghosh ◽  
D Guha
Keyword(s):  
Genital Tract ◽  
Medical Science ◽  
Female Genital Tract ◽  
Cystic Teratoma ◽  
Clinical Findings ◽  
Fallopian Tubes ◽  
Medical College ◽  
Benign Cystic Teratoma ◽  
Set Up ◽  
Female Genital

Aim: To determine frequency of female genital tract (FGT) tuberculosis (TB) in the gynecological biopsies received in the Department of pathology of a peripheral medical college. Methods: This is a retrospective study conducted in the Department of Pathology of Burdwan Medical College & Hospital. Histopathological records of two year (2008-2010) were retrieved and searched for the cases of female genital tract TB. Relevant histopathological findings and clinical data were recorded and analyzed. Results: There were 1537 cases of gynecological biopsy and 9 cases were diagnosed as FGT tuberculosis based on histopathological and clinical findings. Ovarian benign cystic teratoma was seen in one case along with ipsilateral tuberculous salpingitis, one case showed B/L ovarian tuberculosis with involvement of both the tubes. Bilateral fallopian tubes were involved in 2 cases and endometrial tuberculosis was diagnosed in 5 cases with 1 case showing simultaneous involvement of the cervix. In one case omental biopsy received along with tubal specimen showed tuberculous granulomas. Conclusion: FGT tuberculosis was usually seen in  age 16-28 years and constituted 0.59% of total gynecological cases. Fallopian tubes, ovaries and endometrium and cervix were affected with the involvement of peritoneum or omentum, commonest being tuberculous endometritis. Histopathology, in association with clinical findings still remains gold standard for the diagnosis of FGT tuberculosis in our country despite advancement in diagnostic modalities; however, incidental histological detection in clinically unanticipated cases is not an uncommon event. DOI: http://dx.doi.org/10.3329/bjms.v11i3.11719 Bangladesh Journal of Medical Science Vol. 11 No. 03 July’12  

scholarly journals Spectrum of histopathological lesions in the fallopian tubes

2013 ◽  
Vol 3 (5) ◽  
pp. 356-360 ◽  
Author(s):  
S Gon ◽  
A Basu ◽  
B Majumdar ◽  
TK Das ◽  
M Sengupta ◽  
...  
Keyword(s):  
Genital Tract ◽  
Histopathological Examination ◽  
Female Genital Tract ◽  
Secondary Malignancies ◽  
Fallopian Tubes ◽  
Serial Sections ◽  
Pathology Laboratory ◽  
Surgical Specimen ◽  
Neoplastic Lesions ◽  
Female Genital

Background: Fallopian tubes are common surgical specimen in the pathology laboratory; still there is a lack of data to describe the frequency of various histological fi ndings. The aim and objectives of this study was to describe the various histopathological fi ndings of fallopian tubes. Materials and Methods: Two thousand fi ve hundred and seventy fi ve cases where fallopian tubes were removed either separately or along with other female genital tract organs were studied retrospectively and their histopathological fi ndings documented. Results: Ectopic pregnancy comprised maximum number of cases closely followed by salpingitis. Primary neoplastic lesions were rare as compared to secondary malignancies. Serial sections of fallopian tube and sections from representative areas are essential for a pathologist so that the diagnosis of these pathological entities is not missed. Conclusion: Though the fallopian tubes remain unremarkable in majority of the surgical pathological specimens, it must be subjected for histopathological examination to demonstrate the pathological lesions. Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 356-360 DOI: http://dx.doi.org/10.3126/jpn.v3i5.7858

scholarly journals Synchronous primary tumors of the endometrium and ovary

1970 ◽  
Vol 2 (3) ◽  
pp. 189-192 ◽  
Author(s):  
S Karki ◽  
U Chapagain
Keyword(s):  
Genital Tract ◽  
Endometrial Hyperplasia ◽  
Female Genital Tract ◽  
Premenopausal Women ◽  
Ovarian Tumors ◽  
University Teaching ◽  
Primary Tumors ◽  
Atypical Endometrial Hyperplasia ◽  
Ovarian Cancers ◽  
Female Genital

Background: Primary synchronous cancer of the female genital tract is a relatively uncommon. Simultaneously detected endometrial and ovarian malignancies constitute the commonest occurrence. A set of pathological criteria has been described to differentiate synchronous primaries from metastatic tumors. The purpose of this study was to characterize patients with synchronous primary endometrial and ovarian tumors. Materials and Methods: This was a retrospective study done in Department of Pathology, Tribhuwan University Teaching Hospital from September 2006 to August 2011. The datas were retrieved from computer database. Results: There were totally of 10 cases of simultaneously detected endometrial and ovarian cancers. Out of 10 cases, 7 cases were synchronous primary endometrial and ovarian cancers while three were metastatic. Median age at presentation was 47.4 years. Six (85.8%) of these patients presenting with dual primary tumors were premenopausal. Grade 1 histology was seen in 57% of endometrial and 42% of ovarian tumors. Atypical endometrial hyperplasia was found in 42.8% of cases while none of the cases showed endometriosis. Conclusion: Though limited by relatively small number of cases, younger and premenopausal women were predisposed to developing synchronous primary tumors of the endometrium and ovary. DOI: http://dx.doi.org/10.3126/jpn.v2i3.6019 JPN 2012; 2(3): 189-192

scholarly journals Immune Pathogenesis of Asymptomatic Chlamydia trachomatis Infections in the Female Genital Tract

1995 ◽  
Vol 3 (4) ◽  
pp. 169-174 ◽  
Author(s):  
Steven S. Witkin
Keyword(s):  
Chlamydia Trachomatis ◽  
Genital Tract ◽  
Pregnancy Loss ◽  
Early Stage ◽  
Female Genital Tract ◽  
In Vivo Studies ◽  
Fallopian Tubes ◽  
Female Genital

Chlamydia trachomatis (CT) infections of the female genital tract, although frequently asymptomatic, are a major cause of fallopian-tube occlusion and infertility. Early stage pregnancy loss may also be due to an unsuspected and undetected CT infection. In vitro and in vivo studies have demonstrated that this organism can persist in the female genital tract in a form undetectable by culture. The mechanism of tubal damage as well as the rejection of an embryo may involve an initial immune sensitization to the CT 60 kD heat shock protein (HSP), followed by a reactivation of HSP-sensitized lymphocytes in response to the human HSP and the subsequent release of inflammatory cytokines. The periodic induction of human HSP expression by various microorganisms or by noninfectious mechanisms in the fallopian tubes of women sensitized to the CT HSP may eventually result in tubal scarring and occlusion. Similarly, an immune response to human HSP expression during the early stages of pregnancy may interfere with the immune regulatory mechanisms required for the maintenance of a semiallogeneic embryo.

scholarly journals HISTOPATHOLOGICAL STUDY OF NEOPLASTIC LESIONS OF FEMALE GENITAL TRACT IN KOLHAN, JHARKHAND

2018 ◽  
Vol 5 (40) ◽  
pp. 2833-2836
Author(s):  
Shailendra Nath Paul ◽  
Saket Kumar ◽  
Silbina Murmu ◽  
Emmanuel Anurag Soreng
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Histopathological Study ◽  
Neoplastic Lesions ◽  
Female Genital

scholarly journals Cervicovaginal Immune Activation in Zambian Women With Female Genital Schistosomiasis

2021 ◽  
Vol 12 ◽  
Author(s):  
Amy S. Sturt ◽  
Emily L. Webb ◽  
Catriona Patterson ◽  
Comfort R. Phiri ◽  
Tobias Mweene ◽  
...  
Keyword(s):  
Genital Tract ◽  
Multiple Testing ◽  
Female Genital Tract ◽  
Total Sample ◽  
Clinical Findings ◽  
Sub Saharan Africa ◽  
Causal Mechanism ◽  
Cross Sectional ◽  
Hiv 1 ◽  
Female Genital

HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female genital schistosomiasis (FGS), an inflammatory disease caused by S. haematobium egg deposition in the genital tract, has been associated with prevalent HIV-1 infection. Elevated levels of the chemokines MIP-1α (CCL-3), MIP-1β (CCL-4), IP-10 (CXCL-10), and IL-8 (CXCL-8) in cervicovaginal lavage (CVL) have been associated with HIV-1 acquisition. We hypothesize that levels of cervicovaginal cytokines may be raised in FGS and could provide a causal mechanism for the association between FGS and HIV-1. In the cross-sectional BILHIV study, specimens were collected from 603 female participants who were aged 18–31 years, sexually active, not pregnant and participated in the HPTN 071 (PopART) HIV-1 prevention trial in Zambia. Participants self-collected urine, and vaginal and cervical swabs, while CVLs were clinically obtained. Microscopy and Schistosoma circulating anodic antigen (CAA) were performed on urine. Genital samples were examined for parasite-specific DNA by PCR. Women with FGS (n=28), defined as a positive Schistosoma PCR from any genital sample were frequency age-matched with 159 FGS negative (defined as negative Schistosoma PCR, urine CAA, urine microscopy, and colposcopy imaging) women. Participants with probable FGS (n=25) (defined as the presence of either urine CAA or microscopy in combination with one of four clinical findings suggestive of FGS on colposcope-obtained photographs) were also included, for a total sample size of 212. The concentrations of 17 soluble cytokines and chemokines were quantified by a multiplex bead-based immunoassay. There was no difference in the concentrations of cytokines or chemokines between participants with and without FGS. An exploratory analysis of those women with a higher FGS burden, defined by ≥2 genital specimens with detectable Schistosoma DNA (n=15) showed, after adjusting for potential confounders, a higher Th2 (IL-4, IL-5, and IL-13) and pro-inflammatory (IL-15) expression pattern in comparison to FGS negative women, with differences unlikely to be due to chance (p=0.037 for IL-4 and p<0.001 for IL-5 after adjusting for multiple testing). FGS may alter the female genital tract immune environment, but larger studies in areas of varying endemicity are needed to evaluate the association with HIV-1 vulnerability.

scholarly journals Congenital absence of a part of the fallopian tube: a case report

2016 ◽  
Vol 6 (1) ◽  
pp. 320
Author(s):  
Mukta Agarwal ◽  
Hemali H. Sinha ◽  
. Anamika
Keyword(s):  
Case Report ◽  
Fallopian Tube ◽  
Genital Tract ◽  
Rare Case ◽  
Case Reports ◽  
Female Genital Tract ◽  
Fallopian Tubes ◽  
Rare Occurrence ◽  
Rare Case Report ◽  
Female Genital

Congenital malformations of female genital tract are frequently seen in Gynaecological clinics, incidence being upto 5-6% in cases of infertility. Most of these anomalies are related to uterus and vagina, abnormalities related to ovaries and fallopian tubes are of rare occurrence and the exact incidence of these anomalies are not known, only a few incidental case reports are available in literature. Here, we present a rare case report of absent mid- tubal segment of fallopian tube in a patient of infertility.

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