scholarly journals An Interim Report on the Dental Practice Management: COVID-19

2020 ◽  
pp. 1-4
Author(s):  
Somar Mirinal ◽  
Mohadeb-Somar Jhassu Varsha Naveena ◽  
Somar Mirinal
Keyword(s):  
Public Health ◽  
Respiratory Infections ◽  
Close Contact ◽  
Health Crisis ◽  
Healthcare Settings ◽  
New Public Health ◽  
Transmission Modes ◽  
New Public ◽  
Isolation Management ◽  
Novel Coronavirus

There is a new public health crisis threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV). Due to the specialty of oral healthcare settings, the risk of cross infection is severe among patients and oral healthcare practitioners as they work in close proximity to their patients employing droplet and aerosol generating procedures. The transmission modes of SARS-coronavirus appear to be through droplet spread and close contact. Although the principle of universal precautions is widely advocated and followed throughout the dental community, it is not sufficient to help control the spread of this highly contagious disease. Management protocols must be modified to minimize public health risks. This includes the identification, isolation, management and report of possible and probable cases and contacts. Patient assessment should include questions on recent travel to infected areas and, contacts of patients, fever and symptoms of respiratory infections. Hence, there is a need for strict and efficient infection control protocols as the patient may be symptomatic as well as asymptomatic.

scholarly journals SARS-CoV-2 Existence in Different Types of Biological Specimens and Leading Public Health Concern

2020 ◽  
Author(s):  
Priyanka Yadav
Keyword(s):  
Public Health ◽  
Health Care ◽  
Health Care Professionals ◽  
Health Concern ◽  
Health Crisis ◽  
Infected People ◽  
New Public Health ◽  
New Public ◽  
Care Workers ◽  
Novel Coronavirus

There is a new public health crisis threatening the world with the emergence and spread of novel coronavirus (SARS-CoV-2). The outbreak of coronavirus disease 2019 (COVID-19), which originated in Wuhan, China, in December 2019, has been declared a public health emergency of international concern by WHO. Most patients infected with SARS-CoV-2 exhibited symptoms of fever, cough, myalgia, fatigue and shortness of breath. Many infected people may be asymptomatic. It is generally believed that airway exposure to respiratory droplets from an infected patient is the main transmission route of this disease. However, apart from respiratory source, other source specimens like faecal matter and urine could be possible for COVID-19 infectivity. The spreading other routes of the virus has been alarming sign, both for public and health care professionals. Understanding the spreading routes of SARS-CoV-2 is crucial for patient management and defining biosafety strategies for public and health care workers.

Molecular characterization of SARS-CoV-2

2020 ◽  
Vol 20 ◽  
Author(s):  
Miribane Dërmaku-Sopjani ◽  
Mentor Sopjani
Keyword(s):  
Public Health ◽  
Drug Targets ◽  
Virus Genome ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Therapeutic Drugs ◽  
New Public Health ◽  
New Public ◽  
And Function

Abstract:: The coronavirus disease 2019 (COVID-19) is currently a new public health crisis threatening the world. This pandemic disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus has been reported to be originated in bats and by yet unknown intermediary animals were transmitted to humans in China 2019. The SARSCoV- 2 spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERSCoV) but has reduced fatality. At present, the SARS-CoV-2 has caused about a 1.16 million of deaths with more than 43.4 million confirmed cases worldwide, resulting in a serious threat to public health globally with yet uncertain impact. The disease is transmitted by inhalation or direct contact with an infected person. The incubation period ranges from 1 to 14 days. COVID-19 is accompanied by various symptoms, including cough, fatigue. In most people the disease is mild, but in some other people, such as in elderly and people with chronic diseases, it may progress from pneumonia to a multi-organ dysfunction. Many people are reported asymptomatic. The virus genome is sequenced, but new variants are reported. Numerous biochemical aspects of its structure and function are revealed. To date, no clinically approved vaccines and/or specific therapeutic drugs are available to prevent or treat the COVID-19. However, there are reported intensive researches on the SARSCoV- 2 to potentially identify vaccines and/or drug targets, which may help to overcome the disease. In this review, we discuss recent advances in understanding the molecular structure of SARS-CoV-2 and its biochemical characteristics.

scholarly journals COVID-19 in Children and Neonates: A Comprehensive Review Article

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Golnaz Gharehbaghi ◽  
Sedigheh Yousefzadegan ◽  
Asma Javid ◽  
Hamid Riazi-Esfahani ◽  
Ashraf Alsadat Mousavi ◽  
...  
Keyword(s):  
Pediatric Population ◽  
Severe Disease ◽  
Pulmonary Involvement ◽  
Age Group ◽  
Health Crisis ◽  
New Public Health ◽  
The People ◽  
New Public ◽  
Novel Coronavirus ◽  
Underlying Diseases

Context: Novel coronavirus (COVID-19) has become a new public health crisis, posing a great threat to the people all around the world. We aimed to review the articles on COVID-19 in pediatric population to help physicians and other healthcare workers understand the importance of detecting silent disease carriers in this age group and stop further transmission to other healthy individuals and manage symptomatic patients based on the latest recommendations. Methods: We searched databases including PubMed, Scopus, Google Scholar, and Medline and reviewed 70 articles from December 2019 to mid-July 2020. Relevant articles about COVID-19 in children were included. Results: According to the latest reports, 1% - 5% of infected patients were under 19 years old. Death in this age group was rare but it can occur in children with severe disease. The overall course of disease -mainly pulmonary involvement- of the infected children tend to be milder than adults. This may be related to both host factors and exposure. The lab tests and computed tomography (CT) scan findings are nonspecific and milder compared to those in older ages. The cornerstone of COVID-19 management in pediatric group is supportive care. Of note, there is not any approved specific drug for treatment of children affected by COVID-19. Conclusions: COVID-19 disease characteristics in children are not yet fully established, which poses a significant problem for pediatric medical specialists. It should be considered that most children are asymptomatic or have mild symptoms. Critical cases, although uncommon, can occur especially in children with underlying diseases.

scholarly journals Probable immersions for novel Coronavirus and its preventions: A systematic review

2020 ◽  
Author(s):  
Parth M. Kapatel ◽  
Nagma ara Malik
Keyword(s):  
Antiviral Agents ◽  
Severe Infection ◽  
Control Measures ◽  
Health Crisis ◽  
Infection Control Measures ◽  
New Public Health ◽  
New Public ◽  
The World ◽  
Novel Coronavirus

The new public health crisis threatening the world with the emergence due to the spreading of 2019 novel coronavirus (2019-nCoV) or it can also say as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus instigated in bats and was transmitted to humans through yet unknown transitional animals in Wuhan, Hubei province, China in December 2019. There have been around 3.04 million reported cases by WHO of coronavirus disease 2019 (COVID-2019) and 895 thousand are recovered, 211 thousand reported deaths to date (28/04/2020) from all over the world. The disease is spread by inhalation/breathing or interaction with infected droplets. The quarantine period ranges from 2 to 14 days. The symptoms are typically breathlessness, cough, sore throat, fever, fatigue, malaise, among others. The disease is mild in most people; while in about some (generally the aged and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi-organ dysfunction. Many people are asymptomatic. Treatment is very essentially supportive; the role of antiviral agents is up till now to be recognized. Prevention requires home quarantine of alleged cases and those with mild illnesses and severe infection control measures at hospitals that contain interaction, touch and droplet precautions.

scholarly journals The FDA- approved gold drug Auranofin inhibits novel coronavirus (SARS-COV-2) replication and attenuates inflammation in human cells

2020 ◽  
Author(s):  
Hussin A. Rothan ◽  
Shannon Stone ◽  
Janhavi Natekar ◽  
Pratima Kumari ◽  
Komal Arora ◽  
...  
Keyword(s):  
Public Health ◽  
Lung Injury ◽  
Human Cells ◽  
Viral Rna ◽  
Toxicity Profile ◽  
New Public Health ◽  
New Public ◽  
Public Health Threat ◽  
Human Use ◽  
Novel Coronavirus

SummarySARS-COV-2 has recently emerged as a new public health threat. Herein, we report that the FDA-approved gold drug, auranofin, inhibits SARS-COV-2 replication in human cells at low micro molar concentration. Treatment of cells with auranofin resulted in a 95% reduction in the viral RNA at 48 hours after infection. Auranofin treatment dramatically reduced the expression of SARS-COV-2-induced cytokines in human cells. These data indicate that auranofin could be a useful drug to limit SARS-CoV-2 infection and associated lung injury due to its anti-viral, anti-inflammatory and anti-ROS properties. Auranofin has a well-known toxicity profile and is considered safe for human use.

scholarly journals Probable immersions for novel Coronavirus and its preventions: A systematic review

2020 ◽  
Author(s):  
Parth M. Kapatel ◽  
Nagma ara Malik
Keyword(s):  
Antiviral Agents ◽  
Severe Infection ◽  
Control Measures ◽  
Health Crisis ◽  
Infection Control Measures ◽  
New Public Health ◽  
New Public ◽  
The World ◽  
Novel Coronavirus

The new public health crisis threatening the world with the emergence due to the spreading of 2019 novel coronavirus (2019-nCoV) or it can also say as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus instigated in bats and was transmitted to humans through yet unknown transitional animals in Wuhan, Hubei province, China in December 2019. There have been around 3.04 million reported cases by WHO of coronavirus disease 2019 (COVID-2019) and 895 thousand are recovered, 211 thousand reported deaths to date (28/04/2020) from all over the world. The disease is spread by inhalation/breathing or interaction with infected droplets. The quarantine period ranges from 2 to 14 days. The symptoms are typically breathlessness, cough, sore throat, fever, fatigue, malaise, among others. The disease is mild in most people; while in about some (generally the aged and those with comorbidities), it may progress to pneumonia, acute respiratory distress syndrome (ARDS) and multi-organ dysfunction. Many people are asymptomatic. Treatment is very essentially supportive; the role of antiviral agents is up till now to be recognized. Prevention requires home quarantine of alleged cases and those with mild illnesses and severe infection control measures at hospitals that contain interaction, touch and droplet precautions.

scholarly journals COVID-19 Pandemic, Disparity and Vaccine: An Update

2021 ◽  
Vol 2 (1) ◽  
pp. 01-03
Author(s):  
Prabir Mandal
Keyword(s):  
Public Health ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Infections ◽  
Respiratory Illness ◽  
World Health ◽  
Health Concern ◽  
Highly Pathogenic ◽  
New Public Health ◽  
New Public ◽  
Health Organization

Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections in humans. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with zoonotic origin, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), emerged in humans and caused fatal respiratory illness, making emerging coronaviruses a new public health concern in the twenty-first century1. In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally.

scholarly journals The Implementation of the Stay Home Measure and its Effectiveness in Containing the Spread of 2019-nCoV in East African Countries: Case of Rwanda, and Kenya

2020 ◽  
Vol 3 (3) ◽  
pp. 362-371
Author(s):  
Noel Korukire ◽  
Reverien Rutayisire ◽  
Liberatha Rumagihwa ◽  
Isabelle Kayitesi ◽  
Marie Claire Ineza ◽  
...  
Keyword(s):  
Public Health ◽  
Control Measures ◽  
Public Health Issue ◽  
East African ◽  
African Countries ◽  
New Public Health ◽  
New Public ◽  
Daily Report ◽  
Novel Coronavirus ◽  
Selection Of

A novel coronavirus (2019-nCoV), is a new public health issue that is threatening the entire world. The first cases were detected in China by the end of 2019 and spread worldwide rapidly. A significant number of hospitalization and deaths have been recorded globally. So far, Public health measures, including staying at home, are the only available efficient control measures that help to stop the spread of the disease. This paper aims to document how the stay home measure was implemented and highlight its effects on the prevention of the spread of the disease in Rwanda and Kenya. The selection of Kenya and Rwanda was based on the fact that authors able to access the daily report from these countries. The authors reviewed the available literature to inform their views. In Rwanda, the stay-home strategy was strictly enforced, and movements were highly restricted, while in Kenya, movements were allowed in some counties with respect to preventive measures in place.  The authors of this paper conclude that the stay home measure is a key measure to the containment of the spread of the outbreak. The paper recommends further studies to document the statistical association between the mode of implementation of the stay home measure and the decrease of new cases of 2019-nCoV. Rwanda J Med Health Sci 2020;3(3):362-371

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