Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings

2019 ◽  
Author(s):  
Keyword(s):  
Lysine Clonixinate ◽  
Scorpion Stings ◽  
Metamizole Sodium

Descending Cervical-Sacral Pain after the Administration of Antivenom to the Scorpion Sting Poisoning: A Case Report

2020 ◽  
Vol 2 (2) ◽  
pp. 93-96
Author(s):  
Josué Saúl Almaraz Lira ◽  
Alfredo Luis Chávez Haro ◽  
Cristian Alfredo López López ◽  
Remedios del Pilar González Jiménez
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Case Report ◽  
Signs And Symptoms ◽  
Cervical Region ◽  
Scorpion Sting ◽  
Case Presentation ◽  
Sacral Region ◽  
Scorpion Stings

Introduction. Scorpion stings occur mainly in spring and summer, with an estimate of 1.2 million cases per year worldwide. About 300,000 poisonings occur within a year, primarily affecting children and adults older than 65 years. In 2019, Guanajuato (Mexico) ranked third in poisoning by scorpion sting with a total of 43,913 cases. The intoxication grades are three where the signs and symptoms are varied. There are two types of antivenom in the Mexican market, and we use Alacramyn® in our case. Case presentation. A 70-year-old female —with grade 1 scorpion sting poisoning, 30 minutes of evolution, with type 2 diabetes and high blood pressure— received two vials of antivenom according to current regulations. She presented transient vagal reaction and subsequent transient pain in the cervical region that radiates to the sacral region. At discharge, there are no data compatible with scorpion sting poisoning. Conclusions. Transient pain in the cervical region to the sacral region may be secondary to an anxiety crisis, hypersensitivity to IgG, or secondary reaction to administration in less time than recommended by the provider. The benefit was greater than the reactions that occurred.

scholarly journals Lysine clonixinate versus dipyrone (metamizole) for the acute treatment of severe migraine attacks: a single-blind, randomized study

2008 ◽  
Vol 66 (2a) ◽  
pp. 216-220 ◽  
Author(s):  
Abouch Valenty Krymchantowski ◽  
Henrique Carneiro ◽  
Jackeline Barbosa ◽  
Carla Jevoux
Keyword(s):  
Acute Treatment ◽  
Rescue Medication ◽  
International Headache Society ◽  
Randomized Study ◽  
Group 13 ◽  
Lysine Clonixinate ◽  
Inflammatory Drugs ◽  
Rectal Indomethacin ◽  
Single Blind ◽  
Severe Migraine

BACKGROUND AND OBJECTIVE: Nonsteroidal anti-inflammatory drugs (NSAID) are effective to treat migraine attacks. Lysine clonixinate (LC) and dipyrone (metamizol) have been proven effective to treat acute migraine. The aim of this study was to evaluate the efficacy and tolerability of the intravenous formulations of LC and dipyrone in the treatment of severe migraine attacks. METHOD: Thirty patients (28 women, 2 men), aged 18 to 48 years with migraine according the International Headache Society (IHS) (2004) were studied. The patients were randomized into 2 groups when presenting to an emergency department with a severe migraine attack. The study was single-blind. Headache intensity, nausea, photophobia and side effects were evaluated at 0, 30, 60 and 90 minutes after the drug administration. Rectal indomethacin as rescue medication (RM) was available after 2 hours and its use compared between groups. RESULTS: All patients completed the study. At 30 minutes, 0% of the dipyrone group 13% of the LC group were pain free (p=0.46). At 60 and 90 minutes, 2 (13%) and 5 (33%) patients from the dipyrone group and 11 (73%) and 13 (86.7%) patients from the LC group were pain free (p<0.001). At 60 minutes, significantly more patients from the LC group were nausea-free (p<0.001). Regarding photophobia, there were no differences between groups at 60 minutes (p=0.11). The use of RM at 2 hours did not differ among groups (p=0.50). Pain in the site of the injection was reported by more patients of the LC group compared to the dipyrone group (p<0.0001). CONCLUSION: LC is significantly superior to dipyrone in treating severe migraine attacks. LC promotes significantly more burning at the site of the injection.

scholarly journals Australian scorpion stings: a prospective study of definite stings

Toxicon ◽  
2003 ◽  
Vol 41 (7) ◽  
pp. 877-883 ◽  
Author(s):  
Geoffrey K. Isbister ◽  
Erich S. Volschenk ◽  
Corrine R. Balit ◽  
Mark S. Harvey
Keyword(s):  
Prospective Study ◽  
Scorpion Stings ◽  
A Prospective Study

scholarly journals Severe scorpion envenomation in Brazil: clinical, laboratory and anatomopathological aspects

1994 ◽  
Vol 36 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Palmira Cupo ◽  
Mauro Jurca ◽  
Marisa M. Azevedo-Marques ◽  
João Samuel M. Oliveira ◽  
Sylvia E. Hering
Keyword(s):  
Heart Failure ◽  
Pulmonary Edema ◽  
Continuous Monitoring ◽  
Cardiac Involvement ◽  
Clinical Laboratory ◽  
Laboratory Data ◽  
Scorpion Envenomation ◽  
The Hours ◽  
Scorpion Stings

Scorpion stings in Brazil are important not only because of their incidence but also for their potential ability to induce severe, and often fatal, clinical situations, especially among children. In this report we present the clinical and laboratory data of 4 patients victims of scorpion stings by T. serrulatus, who developed heart failure and pulmonary edema, with 3 of them dying within 24 hours of the sting. Anatomopathologic study of these patients revealed diffuse areas of myocardiocytolysis in addition to pulmonary edema. The surviving child presented enzymatic, electrocardiographic and echocardiographic changes compatible with severe cardiac involvement, which were reversed within 5 days. These findings reinforce the need for continuous monitoring of patients with severe scorpion envenoming during the hours immediately following the sting.

Clinical Toxicology of Scorpion Stings

2017 ◽  
pp. 221-238 ◽  
Author(s):  
Manuel Dehesa-davila ◽  
Alejandro C. Alagon ◽  
Lourival D. Possani
Keyword(s):  
Clinical Toxicology ◽  
Scorpion Stings

scholarly journals An epidemiological review of scorpion stings in Venezuela: the Northeastern region

2000 ◽  
Vol 6 (2) ◽  
pp. 128-166 ◽  
Author(s):  
L. DE SOUSA ◽  
P. PARRILLA-ALVAREZ ◽  
M. QUIROGA
Keyword(s):  
Northeastern Region ◽  
Scorpion Stings

scholarly journals Envenomation cases reporting to a rural primary health care center in Maharashtra

2018 ◽  
Vol 5 (12) ◽  
pp. 5265
Author(s):  
Swati Deshpande ◽  
Barsha Pathak ◽  
S. Rahini ◽  
Rukman Mecca
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Care Center ◽  
Primary Health Care Center ◽  
Seasonal Incidence ◽  
Case Record ◽  
Health Care Center ◽  
Primary Health ◽  
Snake Bites ◽  
Scorpion Stings

Background: Annually in the world 1,200,000 cases of envenomation and 3,250 deaths by scorpion stings ensue. Alarming statistics are also seen for snake bites globally i.e. 421,000 envenoming and 20,000 deaths. India is the country with the highest annual number of envenoming (81,000) and deaths (nearly 11,000).Methods: A retrospective cross-sectional study based on hospital record to assess the trend of diverse cases of scorpion sting and snake bite reporting to a rural primary health care center from January 2017 to December 2017. A pre-designed case record proforma was utilized to estimate the percentages of diverse cases of scorpion and snake bites attending the center and assess the demographic profile of the bite cases along with the evaluation of management protocol of these bite cases.Results: 190 cases of envenomation visited the health care center in a year where 165 were scorpion stings and 25 were snake bites. Referral to higher centres for management was established to be more in children and adolescent age groups but the mean age of envenomation was evaluated to be 33.8 years. Remarkable seasonal variation in the envenomation cases was spotted. Anti-snake venom was used for treatment of snake bites but anti-venom was not utilized for scorpion bites.Conclusions: Envenomation cases were common in adults but complications were higher in children and adolescents. We observed gender based risk and a seasonal incidence of envenomation. Most patients of envenomation were successfully managed in rural hospital with limited facilities. 

scholarly journals Relationship Between Scorpion Stings Events and Environmental Conditions in Mainland France

2021 ◽  
Author(s):  
Jules-Antoine Vaucel ◽  
Sébastien Larréché ◽  
Camille Paradis ◽  
Magali Labadie ◽  
Arnaud Courtois ◽  
...  
Keyword(s):  
North Africa ◽  
Environmental Conditions ◽  
Mediterranean Coast ◽  
Poison Control ◽  
Flow Temperature ◽  
The World ◽  
Scorpion Stings ◽  
Multi Center Study ◽  
The Impact ◽  
Amazonian Region

Abstract In the world, the impact of environmental conditions on the number of scorpion events was evaluated in North Africa,Middle East, and the Amazonian region but not in Europe. In mainland France, scorpion species described are Buthus occitanus (Amoreux, 1789), Belisarius xambeui (Simon, 1879) and 4 Euscorpiidae: Euscorpius concinnus (Koch, 1837), Euscorpius italicus (Herbst, 1800), Euscorpius tergestinus (Koch, 1837), and Tetratrichobothrius flavicaudis (De Geer, 1778). We aimed to describe the impact of environmental conduction on the number of scorpion events. For this, a retrospective multi-center study was conducted with data from the French poison control centers files about scorpion events between 1 January 2011 and 31 December 2020. During the study period, 975 incoming calls for scorpion events were recorded and 574 were related to scorpions native to mainland France and Corsica: B. occitanus (n = 86), Euscorpiidae species (n = 222), B. xambeui (n = 1), and undetermined species (n = 265). Cases were mostly reported along the Mediterranean coast, along rivers, and in cities with a trading port. The number of scorpion events was linked to the rivers' water level, rivers' flow, temperature, sunshine, and pluviometry (P &lt; 0.05 for all variables). B. occitanus need warmest and driest environment than Euscorpiidae spp. A link between the severity of the envenoming and climatic condition or seasonality was not demonstrated.

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