A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours)

2019 ◽  
Author(s):  
Keyword(s):  
Advanced Cancer ◽  
Solid Tumours ◽  
Asian Patients ◽  
Different Types ◽  
Different Doses

Cleft palate induction in hamster fetuses by glucocorticoid hormones and their synthetic analogues

Development ◽  
1976 ◽  
Vol 36 (1) ◽  
pp. 101-108
Author(s):  
Ravindra M. Shah ◽  
Alan Kilistoff
Keyword(s):  
Cleft Palate ◽  
Growth Inhibition ◽  
Fetal Growth ◽  
Glucocorticoid Hormones ◽  
Synthetic Analogues ◽  
Total Frequency ◽  
Different Types ◽  
Palatal Development ◽  
Different Doses

The effect of prenatal administration of different doses of cortisone, corticosterone, dexamethasone, triamcinolone and prednisolone on the fetus and its palatal development was studied. All the glucocorticoids, except cortisone, produced cleft palate in the fetuses. Both the total frequency and morphologically different types of cleft palate were related to the dose of the teratogen. Triamcinolone appeared to be more potent than other glucocorticoid in inducing cleft palate. An association was noted between fetal growth inhibition, the dose of the teratogen and the frequency and type of cleft palate.

Rubber Modified Asphalt Storage Stabilizer Option

2011 ◽  
Vol 311-313 ◽  
pp. 1136-1139
Author(s):  
Zhong He Chen ◽  
Zheng Qian Zhang ◽  
Hua Lin Luo ◽  
Ning Ning Dong
Keyword(s):  
Storage Stability ◽  
Experimental Methods ◽  
Modified Asphalt ◽  
The Poor ◽  
Different Types ◽  
And Storage ◽  
Different Doses

In order to improve the poor compatibility and storage stability of rubber modified asphalt,authors using theoretical and experimental methods, to investigate the influence of the stabilizer on the storage stability and the using performance of rubber modified asphalt, through adding the different types and different doses of stabilizer, to improve its storage stability and using performance of modified asphalt.

The teratogenic effects of hydrocortisone on palatal development in the hamster

Development ◽  
1976 ◽  
Vol 35 (1) ◽  
pp. 213-224
Author(s):  
Ravindra M. Shah ◽  
Anthony A. Travill
Keyword(s):  
Cleft Palate ◽  
Close Association ◽  
Fetal Growth Retardation ◽  
Placental Barrier ◽  
Teratogenic Effects ◽  
Different Types ◽  
Palatal Development ◽  
Two Peaks ◽  
Different Doses ◽  
Hydrocortisone Treatment

The effect of different doses of hydrocortisone, administered at various times during gestation, on the fetal hamster and its palatal development was studied. Both the frequency of cleft palate and that of resorption depended upon the dose of hydrocortisone and the time of its administration. Two peaks in the incidence of cleft palate were observed, which appeared to be due to inhibition of different events. Incidence of morphologically different types of cleft palate was related to the doses and gestational time of hydrocortisone treatment. A close association was observed between the frequency of cleft palate and fetal growth retardation and between the latter and the dose and time of drug administration. It was suggested that maternal physiology and the placental barrier may play a crucial role in cleft palate induction.

scholarly journals 1965P Detection of BRCA1/2 mutations using next-generation sequencing in Asian patients with solid tumours

2020 ◽  
Vol 31 ◽  
pp. S1105
Author(s):  
K.T. Tan ◽  
H-Y. Lu ◽  
Y-H. Jan ◽  
Y-L. Hsieh ◽  
D-W. Zhuo ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Solid Tumours ◽  
Next Generation ◽  
Asian Patients ◽  
Generation Sequencing

scholarly journals Pooled safety analysis of tepotinib in Asian patients with advanced solid tumours

2019 ◽  
Vol 30 ◽  
pp. ix26 ◽  
Author(s):  
K. Yamazaki ◽  
B.-Y. Ryoo ◽  
T. Doi ◽  
P.K. Paik ◽  
R. Veillon ◽  
...  
Keyword(s):  
Safety Analysis ◽  
Solid Tumours ◽  
Asian Patients

Nanoscale porous organic polymers for drug delivery and advanced cancer theranostics

2021 ◽  
Author(s):  
Nem Singh ◽  
Subin Son ◽  
Jusung An ◽  
Ilwha Kim ◽  
Minhyeok Choi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Advanced Cancer ◽  
Organic Polymers ◽  
Porous Organic Polymers ◽  
Diagnosis And Therapy ◽  
Different Types ◽  
Cancer Theranostics

This tutorial review highlights the potential of nanoscale porous organic polymers in diagnosis and therapy of different types of cancers.

Immersive technology in ophthalmology education: a systematic review

2021 ◽  
pp. bmjstel-2021-000906
Author(s):  
Shakeel Lowe ◽  
Kathryn Mares ◽  
Zarnie Khadjesari
Keyword(s):  
Systematic Review ◽  
Teaching Practices ◽  
Conventional Teaching ◽  
Different Types ◽  
Standard Training ◽  
And Performance ◽  
Randomised Controlled ◽  
Value Of It ◽  
Different Doses ◽  
Immersive Technology

BackgroundDespite the increasing use of immersive technology (IT) in ophthalmology, the effectiveness of this approach compared to other teaching practices is unclear. This systematic review aimed to determine the value of IT to teach students ophthalmic skills and whether it can supplement or replace conventional teaching practices.MethodsA systematic search was performed of CENTRAL, MEDLINE, EMBASE, ERIC and PsychINFO databases. Randomised controlled trials comparing IT interventions versus (1) no training, (2) standard training, (3) different types of IT interventions, (4) different doses of IT interventions were eligible for inclusion.ResultsSeven trials involving 177 participants were included. IT offered some benefit compared to standard training as most trials demonstrated evidence of learning represented by composite performance score and performance time. Repetitive training with IT displayed similar results.ConclusionIT appears to improve the ophthalmic skill of healthcare trainees and should be considered as a supplement to training.

scholarly journals Latest Evidence on Using Hormone Replacement Therapy in the Menopause

2018 ◽  
Vol 36 (1) ◽  
pp. 26-32
Author(s):  
Mst Jesmin Akter ◽  
Eliza Shirin
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Multidisciplinary Approach ◽  
Hormone Replacement ◽  
Individual Decision ◽  
Ovarian Insufficiency ◽  
Menopausal Women ◽  
Different Types ◽  
Different Doses

Hormone replacement therapy (HRT) is the most effective therapy of menopausal symptoms for perimenopausal and menopausal women. When HRT is individually tailored women gain maximum advantages and the risk are minimized. There are different types of hormones with different doses and different routes of delivery exist. . The use of HRT is an individual decision which women can only make once she has been given correct information and advice from healthcare professionals. HRT should be recommended in women with premature ovarian insufficiency with advice to continue until the average age of menopause at 51.4 years. This review item promotes confidence in prescribing HRT in most symptomatic women. Prescribing HRT in women with relative contraindication where evidence is limited. Quality of life is priority. Multidisciplinary approach may be necessary and informed written consent documented.J Bangladesh Coll Phys Surg 2018; 36(1): 26-32

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