scholarly journals THE POSSIBILITIES OF COMPLEX VISUAL DIAGNOSTICS OF LIVER PATHOLOGY IN PATIENTS WITH DIFFUSE LIVER DISEASES ASSOCIATED WITH COVID-19.

2021 ◽  
Vol 4 (11(75)) ◽  
pp. 41-45
Author(s):  
A. Telesh ◽  
T. Morozova
Keyword(s):  
Liver Diseases ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Diagnostic Methods ◽  
Hospital Treatment ◽  
Liver Pathology ◽  
Resonance Imaging ◽  
Specific Diagnosis ◽  
Magnetic Resonance Imaging Mri ◽  
Diffuse Liver Diseases

The research shows the possibilities of visual diagnostics of liver pathology in patients with various diffuse liver diseases and COVID-19. The analysis is based on the results of examination of patients, who got hospital treatment in Clinical Hospital №1 of Smolensk from September to November 2021. The research shows the efficiency of ultrasound diagnosis as the first step of examination. Using Magnetic Resonance Imaging (MRI) allowed to study the symptoms of liver pathology more deeply. In order to improve the exact specific diagnosis of liver pathology in patients with diffuse liver diseases and COVID-19, arterial spin labeling technique is recommended to use. The research shows the efficiency of complex using of diagnostic methods in patients with diffuse liver diseases and SARS-CoV-2 infection

scholarly journals Impact of Arginase II on CBF in Experimental Cortical Impact Injury in Mice Using MRI

2010 ◽  
Vol 30 (6) ◽  
pp. 1105-1109 ◽  
Author(s):  
Brittany R Bitner ◽  
Danielle C Brink ◽  
Leela C Mathew ◽  
Robia G Pautler ◽  
Claudia S Robertson
Keyword(s):  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Brain Regions ◽  
No Production ◽  
Resonance Imaging ◽  
Low Levels ◽  
Arginase Ii ◽  
Magnetic Resonance Imaging Mri ◽  
Hemodynamic Processes ◽  
Impact Injury

Traumatic brain injury (TBI) results in reduced cerebral blood flow (CBF) and low levels of the vasodilator nitric oxide (NO) may be involved. Arginase II negatively regulates NO production through competition for the substrate L-arginine. We determined whether arginase II-deficient (ArgII−/−) mice would show improved CBF after TBI through arterial spin-labeling magnetic resonance imaging (MRI). The ArgII−/− mice exhibit a significantly improved CBF recovery after trauma in the perilesional brain ( P=0.0015) and in various other brain regions. In conclusion, arginase II deficiency leads to a better CBF recovery after TBI and implicates arginase II in hemodynamic processes.

scholarly journals Efficacy of arterial spin labeling for detection of the ruptured micro-arteriovenous malformation: illustrative cases

2022 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Arterial Spin Labeling ◽  
Screening Tool ◽  
Spin Labeling ◽  
Acute Stage ◽  
Digital Subtraction ◽  
Resonance Imaging ◽  
Internal Wall ◽  
Lobar Hemorrhage ◽  
Magnetic Resonance Imaging Mri ◽  
Standard Magnetic Resonance Imaging

BACKGROUND Diagnosis of a microarteriovenous malformation (micro-AVM) is difficult, especially in the acute stage of rupture because of the small size of the nidus and the existence of hematoma. We report two cases of ruptured micro-AVMs detected by arterial spin labeling (ASL). OBSERVATIONS In one case, a 45-year-old male was transported with a complaint of right hemiparesis. Computed tomography (CT) revealed a right parietal lobar hemorrhage. Standard magnetic resonance imaging (MRI) showed no abnormal findings as the cause of the hemorrhage. ASL 23 days after the onset demonstrated high signals on the medial wall of the hematoma. Digital subtraction angiography (DSA) showed a micro-AVM in accordance with the site of high signals on ASL. In another case, a 38-year-old female was transported with a complaint of left hemianopsia. CT on admission revealed a right parietal lobar hemorrhage. Standard MRI showed no abnormal findings as the cause of the hemorrhage. ASL 15 days after the onset demonstrated high signals on the internal wall of the hematoma. DSA showed micro-AVM in accordance with the site of high signaling on ASL. Both cases were successfully treated with open surgery. LESSONS ASL can manifest micro-AVMs as high signals within the hematoma. ASL is a useful less-invasive screening tool for the detection of ruptured micro-AVMs.

scholarly journals Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion

2019 ◽  
Vol 40 (9) ◽  
pp. 1869-1878 ◽  
Author(s):  
Doeschka A Ferro ◽  
Henri JJM Mutsaerts ◽  
Saima Hilal ◽  
Hugo J Kuijf ◽  
Esben T Petersen ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Cerebral Perfusion ◽  
Region Of Interest ◽  
Resonance Imaging ◽  
Memory Clinic ◽  
Anterior Circulation ◽  
Cortical Gray Matter ◽  
Arterial Transit Time ◽  
Magnetic Resonance Imaging Mri ◽  
Continuous Arterial Spin Labeling

Cerebral cortical microinfarcts (CMIs) are small ischemic lesions associated with cognitive impairment and dementia. CMIs are frequently observed in cortical watershed areas suggesting that hypoperfusion contributes to their development. We investigated if presence of CMIs was related to a decrease in cerebral perfusion, globally or specifically in cortex surrounding CMIs. In 181 memory clinic patients (mean age 72 ± 9 years, 51% male), CMI presence was rated on 3-T magnetic resonance imaging (MRI). Cerebral perfusion was assessed from cortical gray matter of the anterior circulation using pseudo-continuous arterial spin labeling parameters cerebral blood flow (CBF) (perfusion in mL blood/100 g tissue/min) and spatial coefficient of variation (CoV) (reflecting arterial transit time (ATT)). Patients with CMIs had a 12% lower CBF (beta = −.20) and 22% higher spatial CoV (beta = .20) (both p < .05) without a specific regional pattern on voxel-based CBF analysis. CBF in a 2 cm region-of-interest around the CMIs did not differ from CBF in a reference zone in the contralateral hemisphere. These findings show that CMIs in memory clinic patients are primarily related to global reductions in cerebral perfusion, thus shedding new light on the etiology of vascular brain injury in dementia.

Arterial spin-labeling magnetic resonance imaging for diagnosis of early seizure after stroke

2015 ◽  
Vol 354 (1-2) ◽  
pp. 127-128 ◽  
Author(s):  
Yosuke Miyaji ◽  
Yuichi Kawabata ◽  
Hideto Joki ◽  
Shunsuke Seki ◽  
Kentaro Mori ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Resonance Imaging ◽  
Early Seizure

Bone-related disorders of the jaw: A clinico-radiological diagnostic algorithm

2021 ◽  
pp. 197140092199896
Author(s):  
Ahmed Abdel Khalek Abdel Razek
Keyword(s):  
Diagnostic Algorithm ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Specific Diagnosis ◽  
Clinical Presentations ◽  
Neoplastic Lesions ◽  
Lesion Extension ◽  
Magnetic Resonance Imaging Mri ◽  
The Relationship ◽  
Ct And Mri

Bone-related disorders of the jaw (BRDJ) include a spectrum of non-neoplastic and neoplastic lesions of the maxillofacial region that have been recently classified into fibro-osseous lesions, giant cell lesions and osseous tumours. The histopathological features of BRDJ can be similar and overlie each other. Imaging is important in order to reach a specific diagnosis. However, the appearance of BRDJ on imaging is non-specific in some cases. Computed tomography (CT) and magnetic resonance imaging (MRI) are used for accurate localisation, characterisation of the tumour matrix, delineation of the lesion extension and establishment of the relation of BRDJ to the surrounding structures. Imaging is usually done to detect the relationship with the adjacent surrounding vital structures and to diagnose aggressive forms, malignant transformation and associated syndromes. The correlation of the demographic findings, the location and the clinical presentations with the imaging features are important for the diagnosis of BRDJ. The proposed clinico-radiological diagnostic algorithm with CT and MRI helps a specific diagnosis to be reached in some cases.

Arterial Spin Labeling for the Etiological Workup of Intracerebral Hemorrhage in Children

Stroke ◽  
2021 ◽  
Author(s):  
Jean François Hak ◽  
Grégoire Boulouis ◽  
Basile Kerleroux ◽  
Sandro Benichi ◽  
Sarah Stricker ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Intracerebral Hemorrhage ◽  
Computed Tomography Angiography ◽  
Arterial Spin Labeling ◽  
Diagnostic Performance ◽  
Spin Labeling ◽  
Digital Subtraction ◽  
Resonance Imaging

Background and Purpose: Pediatric nontraumatic intracerebral hemorrhage accounts for half of stroke in children. Early diagnostic of the causative underlying lesion is the first step toward prevention of hemorrhagic recurrence. We aimed to investigate the performance of arterial spin labeling sequence (ASL) in the acute phase etiological workup for the detection of an arteriovenous shunt (AVS: including malformation and fistula), the most frequent cause of pediatric nontraumatic intracerebral hemorrhage. Methods: Children with a pediatric nontraumatic intracerebral hemorrhage between 2011 and 2019 enrolled in a prospective registry were retrospectively included if they had undergone ASL-magnetic resonance imaging before any etiological treatment. ASL sequences were reviewed using cerebral blood flow maps by 2 raters for the presence of an AVS. The diagnostic performance of ASL was compared with admission computed tomography angiography, other magnetic resonance imaging sequences including contrast-enhanced sequences and subsequent digital subtraction angiography. Results: A total of 121 patients with pediatric nontraumatic intracerebral hemorrhage were included (median age, 9.9 [interquartile range, 5.8–13]; male sex 48.8%) of whom 76 (63%) had a final diagnosis of AVS. Using digital subtraction angiography as an intermediate reference, visual ASL inspection had a sensitivity and a specificity of, respectively, 95.9% (95% CI, 88.5%–99.1%) and 79.0% (95% CI, 54.4%–94.0%). ASL had a sensitivity, specificity, and accuracy of 90.2%, 97.2%, and 92.5%, respectively for the detection of the presence of an AVS, with near perfect inter-rater agreement (κ=0.963 [95% CI, 0.912–1.0]). The performance of ASL alone was higher than that of other magnetic resonance imaging sequences, individually or combined, and higher than that of computed tomography angiography. Conclusions: ASL has strong diagnostic performance for the detection of AVS in the initial workup of intracerebral hemorrhage in children. If our findings are confirmed in other settings, ASL may be a helpful diagnostic imaging modality for patients with pediatric nontraumatic intracerebral hemorrhage. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifiers: 3618210420, 2217698.

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