scholarly journals Antioxidants, polyphenols, and health benefits of cherry laurel: a review

2020 ◽  
Vol 10 ◽  
Author(s):  
Cesarettin Alasalvar ◽  
Sui Kiat Chang
Keyword(s):  
Clinical Trials ◽  
Health Benefits ◽  
The Black Sea ◽  
Good Source ◽  
Black Sea Region ◽  
Nutritional Characteristics ◽  
High Antioxidant Activity ◽  
Summer Fruit ◽  
Cherry Laurel

Cherry laurel (dark purple or black when mature) is a popular summer fruit in the Black Sea region of Turkey. It has been gaining popularity as a valuable source of healthy fruit over the last two decades and is a good source of nutrients and polyphenols together with high antioxidant activity. This contribution discusses nutritional characteristics, antioxidants, polyphenols, and health benefits of cherry laurel. Where available, comparisons are made with other cherry fruits (Cornelian, sweat, and sour) and blueberry. Although several health benefits of this fruit and its seeds have been known as home-made and traditional medicine, in vivo and well-designed human clinical trials are scarce. Therefore, additional carefully-designed human clinical trials are needed to validate the health benefits of this fruit.

Chemical and Antioxidant Properties ofLaurocerasus officinalisRoem. (Cherry Laurel) Fruit Grown in the Black Sea Region

2003 ◽  
Vol 51 (25) ◽  
pp. 7489-7494 ◽  
Author(s):  
Sevgi Kolayli ◽  
Murat Küçük ◽  
Celal Duran ◽  
Ferda Candan ◽  
Barbaros Dinçer
Keyword(s):  
Black Sea ◽  
Antioxidant Properties ◽  
The Black Sea ◽  
Black Sea Region ◽  
Cherry Laurel

Obsidian Exchange Networks in Prehistoric Anatolia: New Data from the Black Sea Region

Paléorient ◽  
2013 ◽  
Vol 39 (2) ◽  
pp. 173-182
Author(s):  
Bleda S. Düring ◽  
Bernard Gratuze
Keyword(s):  
Black Sea ◽  
The Black Sea ◽  
Exchange Networks ◽  
Black Sea Region

The referendum as an institution in the Black Sea Region: Does it signal the rise or collapse of democracy?

2019 ◽  
Vol 17 (4) ◽  
pp. 161-185
Author(s):  
Małgorzata Podolak
Keyword(s):  
Black Sea ◽  
Direct Democracy ◽  
The Black Sea ◽  
Moral Issues ◽  
Black Sea Region ◽  
Positive Effects ◽  
The Subject ◽  
Democratic Systems ◽  
Important State ◽  
Constitutional Changes

Views on the institution of direct democracy have changed during the period of democratic transition. The various advantages and positive effects of direct democracy have been confirmed by the practice of some democratic countries. Its educational and political activation value for society was also noted, without which civil society cannot form. The referendum is especially treated as the purest form of correlation between the views of society and the decisions of its representatives. In a situation where two representative bodies are present – the parliament and the president – a referendum is considered a means of resolving disputes between them in important state affairs. The referendum is nowadays becoming more than just a binding or consultative opinion on a legislative act, especially a constitution. First and foremost, it is important to see the extension of the type and scope of issues that are subject to direct voting. Apart from the traditional, i.e., constitutional changes, polarising issues that raise considerable emotion have become the subject of referenda. Problems of this type include, in particular, moral issues, membership in international organisations, and so-called ‘New Policy’. This article presents the role and importance of the referendum as an institution shaping the democratic systems of the Black Sea Region.

RESEARCH OF FEATURES OF FOREIGN ECONOMIC TRADE OF REGIONAL ECONOMY SERVICES

2019 ◽  
pp. 44-51
Author(s):  
Andrii ZAVHORODNII
Keyword(s):  
Foreign Trade ◽  
Economic Activity ◽  
Trade Balance ◽  
Well Being ◽  
General Situation ◽  
The Black Sea ◽  
Reduction Peak ◽  
Black Sea Region ◽  
Economic Relations ◽  
Export Dynamics

Abstract Introduction. Nowadays the foreign economic activity of the regions serves as a factor contributing to improving the population well-being, improving its life quality, as well as territory socio-economic development and increasing its competitiveness. The purpose of the article is to analyze the foreign trade in services at the regional level and to identify its features. Results. The comparative analysis of the services export dynamics was conducted in the studied regions for the period from 1996 to 2018: the periods of growth, reduction, peak values were identified, the leader – Odessa region was determined. At the same time, it is emphasized that due to the decrease in the indicator in Odessa region and the growth in the Mykolaiv region, the gap between them narrowed significantly for the period from 2012. The dynamics of the services import volume in the economy of the studied regions has been analyzed. Determination of the leader – Odessa region was done, the trends of dynamics for the studied period are considered. The dynamics calculation of the foreign trade balance in services in the Mykolayiv region is given. The calculation of the chain gains index of the services foreign trade balance in the Mykolaiv region is given, which indicates a considerable amplitude of fluctuations and reduction from 2014 to 2016. Results. The foreign trade balance in services in the studied areas was calculated and analyzed: the Odessa region was the leader before 2010. After in accordance with the services export dynamics in Odessa and Mykolaiv regions, their convergence to the actual equalization in 2018 is observed. The positive value of the balance in all the regions for the whole study period is noteworthy. The analysis makes it possible to confirm the significant dependence of the foreign regions economic activity of the Black Sea region on the general situation in the country with divergent tendencies of indicators changes, which allows to define it as heterogeneous. Keywords: foreign economic activity of the region, export, import, dynamics, regional foreign economic relations, foreign economic relations of the region.

Modulation of Matrix Metalloproteinases by Plant-Derived Products

2020 ◽  
Vol 20 ◽  
Author(s):  
Nur Najmi Mohamad Anuar ◽  
Nurul Iman Natasya Zulkafali ◽  
Azizah Ugusman
Keyword(s):  
Clinical Trials ◽  
Natural Products ◽  
Matrix Metalloproteinases ◽  
Animal Studies ◽  
Current Knowledge ◽  
In Vitro Models ◽  
In Vivo Studies ◽  
Extracellular Matrix Components

: Matrix metalloproteinases (MMPs) are a group of zinc-dependent metallo-endopeptidase that are responsible towards the degradation, repair and remodelling of extracellular matrix components. MMPs play an important role in maintaining a normal physiological function and preventing diseases such as cancer and cardiovascular diseases. Natural products derived from plants have been used as traditional medicine for centuries. Its active compounds, such as catechin, resveratrol and quercetin, are suggested to play an important role as MMPs inhibitors, thereby opening new insights into their applications in many fields, such as pharmaceutical, cosmetic and food industries. This review summarises the current knowledge on plant-derived natural products with MMP-modulating activities. Most of the reviewed plant-derived products exhibit an inhibitory activity on MMPs. Amongst MMPs, MMP-2 and MMP-9 are the most studied. The expression of MMPs is inhibited through respective signalling pathways, such as MAPK, NF-κB and PI3 kinase pathways, which contribute to the reduction in cancer cell behaviours, such as proliferation and migration. Most studies have employed in vitro models, but a limited number of animal studies and clinical trials have been conducted. Even though plant-derived products show promising results in modulating MMPs, more in vivo studies and clinical trials are needed to support their therapeutic applications in the future.

Hearing the Crimean War

2019 ◽  
Keyword(s):  
Nineteenth Century ◽  
Sound Studies ◽  
The Black Sea ◽  
Crimean War ◽  
National Unity ◽  
Black Sea Region ◽  
Academic Fields ◽  
History Of ◽  
The Many

This book addresses the sounds of the Crimean War, along with the many ways nineteenth-century wartime is aurally constructed. It examines wide-ranging experiences of listeners in Britain, France, Turkey, Russia, Italy, Poland, Latvia, Daghestan, Chechnya, and Crimea, illustrating the close interplay between nineteenth-century geographies of empire and the modes by which wartime sound was archived and heard. This book covers topics including music in and around war zones, the mediation of wartime sound, the relationship between sound and violence, and the historiography of listening. Individual chapters concern sound in Leo Tolstoy’s wartime writings, and his place within cosmopolitan sensibilities; the role of the telegraph in constructing sonic imaginations in London and the Black Sea region; the absence of archives for the sounds of particular ethnic groups, and how songs preserve memories for both Crimean Tatars and Polish nationalists; the ways in which perceptions of voice rearranged the mental geographies of Baltic Russia, and undermined aspirations to national unity in Italy; Italian opera as a means of conditioning elite perceptions of Crimean battlefields; and historical frames through which to understand the diffusion of violent sounds amid everyday life. The volume engages the academic fields of musicology, ethnomusicology, history, literary studies, sound studies, and the history of the senses.

scholarly journals Whither Magnetic Hyperthermia? A Tentative Roadmap

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 706
Author(s):  
Irene Rubia-Rodríguez ◽  
Antonio Santana-Otero ◽  
Simo Spassov ◽  
Etelka Tombácz ◽  
Christer Johansson ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Nanoparticle Synthesis ◽  
Careful Analysis ◽  
Magnetic Hyperthermia ◽  
Lessons Learned ◽  
In Vivo Testing ◽  
Evolution Of Science ◽  
Made In ◽  
Critical Aspects

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.

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