scholarly journals Spices and herbs as immune enhancers and anti-inflammatory agents: A review

2021 ◽  
Vol 14 ◽  
Author(s):  
Andrew Garnier ◽  
Fereidoon Shahidi

Spices and herbs have been used in traditional medicine for centuries, with research starting to accumulate on their beneficial properties. Of these properties, the immune-enhancing and anti-inflammatory capabilities of many spices and herbs have led to promising results. The current review article aims to explore the current research of several spices and herbs as immune-enhancers and anti-inflammatory agents. The spices and herbs examined are African potato (Hypoxis hemerocallidea), allspice (Pimenta dioica), basil (Ocimum basilicum), black pepper (Piper nigrum), chili powders (Capsicum species), clove (Syzygium aromaticum), Devil’s claw (Harpagophytem procumbens), fenugreek (Trigonella foenum-graecum), ginger (Zingiber officinale), lavender (Lavandula angustifolia), oregano (Origanum vulgare), rooibos (Aspalathus linearis), rosemary/sage (Salvia rosmarinus/officinalis), saffron (Crocus sativus), South African geranium (Pelargonium sidoides), and turmeric (Curcuma longa). All the spices and herbs exhibited immune-enhancing or immunomodulatory and anti-inflammatory capabilities through various processes. Rooibos and oregano had the most contradictory results, with some studies finding pro-inflammatory properties, especially at high doses regarding oregano. Turmeric had the most extensive research with positive results.

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Christine T. Peterson ◽  
Dmitry A. Rodionov ◽  
Stanislav N. Iablokov ◽  
Meredith A. Pung ◽  
Deepak Chopra ◽  
...  

Although the impact of medicinal and culinary herbs on health and disease has been studied to varying extents, scarcely little is known about the impact of these herbs on gut microbiota and how such effects might contribute to their health benefits. We applied in vitro anaerobic cultivation of human fecal microbiota followed by 16S rRNA sequencing to study the modulatory effects of 4 culinary spices: Curcuma longa (turmeric), Zingiber officinale (ginger), Piper longum (pipli or long pepper), and Piper nigrum (black pepper). All herbs analyzed possessed substantial power to modulate fecal bacterial communities to include potential prebiotic and beneficial repressive effects. We additionally analyzed the sugar composition of each herb by mass spectrometry and conducted genome reconstruction of 11 relevant sugar utilization pathways, glycosyl hydrolase gene representation, and both butyrate and propionate biosynthesis potential to facilitate our ability to functionally interpret microbiota profiles. Results indicated that sugar composition is not predictive of the taxa responding to each herb; however, glycosyl hydrolase gene representation is strongly modulated by each herb, suggesting that polysaccharide substrates present in herbs provide selective potential on gut communities. Additionally, we conclude that catabolism of herbs by gut communities primarily involves sugar fermentation at the expense of amino acid metabolism. Among the herbs analyzed, only turmeric induced changes in community composition that are predicted to increase butyrate-producing taxa. Our data suggests that substrates present in culinary spices may drive beneficial alterations in gut communities thereby altering their collective metabolism to contribute to the salubrious effects on digestive efficiency and health. These results support the potential value of further investigations in human subjects to delineate whether the metabolism of these herbs contributes to documented and yet to be discovered health benefits.


Author(s):  
S. Devasahayam ◽  
T. K. Jacob ◽  
C. M. Senthil Kumar ◽  
M Balaji Rajkumar

Pest control strategies based on relatively non-toxic procedures that preserve the health of the ecosystem and minimizes negative effects on beneficial organisms, and utilize microbial pathogens and their products, plant natural products, semiochemicals, biotechnological strategies and reduced-risk pesticides can be termed as ‘biorational strategies’. This review consolidates the information available on the use of biorational strategies for the management of insect pests of spice crops such as Piper nigrum (black pepper), Elettaria cardamomum (cardamom), Zingiber officinale (ginger), Curcuma longa (turmeric), Coriandrum sativum (coriander), Cuminum cyminum (cumin) and Foeniculum vulgare (fennel). The review also identifies the current gaps in knowledge and the opportunities and challenges in using biorational strategies for the production of clean spices, reflecting the global concern over pesticide misuse.


2018 ◽  
Vol 21 (1) ◽  
pp. 55-62
Author(s):  
Muhammad Riaz ◽  
Saima Manzoor ◽  
Sadia Naseem ◽  
Sehrish Saddiq ◽  
Rehana Rashid

Five exotic dietary and medicinal spices (Trachyspermum ammi, Curcuma longa, Piper nigrum (Black pepper, Anacardium occidentate, Syzygium aromaticum) were studied for their metal contaminations, phenolic contents, antioxidant and antibacterial properties. White pepper contains maximum phenolic contents and black pepper showed higher antioxidant potential. Clove showed maximum antimicrobial potential (25-30 mm) against Escherichia coli and Staphylococcus aureus (18-21 mm). White pepper contained maximum phenolic contents. Estimation of metal contamination in spices indicated that K, Ca, Mg, Cu, Co, As, Hg, Mo were above the standard permissible limits (SPL), Cr, Ni and Cd within standard permissible limits, whereas, Fe, Zn, Mn and Pb were below standard permissible limits.Bangladesh Pharmaceutical Journal 21(1): 55-62, 2018


1970 ◽  
Vol 27 ◽  
pp. 47-50 ◽  
Author(s):  
Shah Hussain Ahmad Mahdi ◽  
Md Khaladur Rahman

The experiment was conducted to investigate the insecticidal potency of some spices eg. clove (Syzygium aromaticum), black pepper (Piper nigrum), ceylon cinnamon (Cinnamomum zeylanicum), black cardamom (Amomum subulatum), nutmeg (Myristica fragnans), black cumin (Nigella sativa), turmeric (Curcuma longa), red pepper (Capsicum frutescens), cumin (Cuminum cyminum), green cardamom (Elettaria cardamomum) and bay leaf (Cinnamomum tamala), against the pulse beetle, Callosobruchus maculatus (F.) on stored black gram (Phaseolus bengalensis L.). Data were recorded on days to 100% mortality; number of adults emerged and weight loss (%) of black gram. All the spices were effective as protectants of black gram seeds. However, clove and black pepper were most effective. Key words: Callosobruchus maculatus, stored black gram, mortality, adult emerge, extent of damage. doi:10.3329/ujzru.v27i0.1953 Univ. j. zool. Rajshahi Univ. Vol. 27, 2008 pp. 47-50


2020 ◽  
Vol 11 (4) ◽  
pp. 11122-11134

As of now, Coronavirus (COVID-19) is spreading overall quickly, and its control is troublesome because there is no compelling immunization or medications accessible in the medical sector. This contagious disease has been associated with numerous respiratory issues. Thus, there is a crucial need to elucidate plant-derived compounds that display inhibitory potential against potential targets of coronavirus and boost the human body's immunity. This infection can contaminate the individuals and cause diseases of the respiratory lot. This research has focused on exploiting the medicinal properties of phytocompounds of three plants that have shown significant anti-inflammatory potential and had been effective against numerous respiratory disorders. This research's main objective was to study the inhibitory potential of these selected twenty-seven phytocompounds derived from Piper nigrum, Syzygium aromaticum, and Zingiber officinale roscoe against protease of COVID-19. We performed screening of selected phytocompounds with antivirus action by employing different in silico approaches, including Lipinski rule of five, adme analysis, and molecular docking tools. In silico investigation has revealed the inhibitory potential of these selected ligands (phytocompounds), two crucial targets of coronavirus, including 6LU7 and 7JTL. Out of 27 selected phytocompounds guaiol and gingeronone A has displayed significant inhibitory potential against coronavirus's selected targets. Thus our research findings strongly recommended that phytocompounds derived from black pepper, clove, and ginger could be very useful in battling the COVID-19 pandemic era.


2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Mona Ghasemian ◽  
Sina Owlia ◽  
Mohammad Bagher Owlia

Medicinal plants and their secondary metabolites are progressively used in the treatment of diseases as a complementary medicine. Inflammation is a pathologic condition that includes a wide range of diseases such as rheumatic and immune-mediated conditions, diabetes, cardiovascular accident, and etcetera. We introduce some herbs which their anti-inflammatory effects have been evaluated in clinical and experimental studies.Curcuma longa, Zingiber officinale, Rosmarinus officinalis, Borago officinalis, evening primrose, and Devil’s claw are some of the introduced medicinal herbs in this review. Since the treatment of inflammation is not a one-dimensional remedy, this review tries to reach a multidimensional therapeutic approach to inflammation with the help of herbal medicine and modification in lifestyle.


Author(s):  
Danish Javed ◽  
Ashish Kumar Dixit

Abstract Objectives The aim of this review is to summarise and appraise the findings of various studies on Trikatu. Content COVID-19 or SARS-CoV-2 disease a pandemic principally contaminating the respiratory tract and bringing about Severe Acute Respiratory Syndrome is liable for significant mortality around the world. Far-fetched, there is no exact treatment accessible till today. Consequently, it is critical to discover the alternative methodology which can decrease the weight of illness. Trikatu powder recommended by authorities for the management of mild cases of COVID-19 is a conventional ayurvedic formulation containing three spices; Zingiber officinale, Piper nigrum, and Piper longum. A comprehensive search of the articles published since inception to 01/08/2020 on Trikatu was carried out. Major electronic medical databases such as Pub Med/MEDLINE and Cochrane Database of Systematic Reviews were used for the literature search. Summary A total of 21 records were identified by electronic searches between since inception to 01/08/2020 of which 13 records were included for review. The reviewed articles highlight Trikatu as a safe, anti-inflammatory, and immune-modulatory property by suppression of the production of pro-inflammatory cytokines TNF-a, IL-1b, IL-6, IL-17, alteration in levels of circulating immune complexes, anti-dyslipidaemia agent by reduced triglycerides and LDL cholesterol and increased HDL cholesterol, enhancing bio-availability of co-drug by reducing the elimination half-life (t1/2β) and zero time intercept of the elimination phase. Outlook The findings of this review seem to show Trikatu as a potential anti-inflammatory, anti-dyslipidaemia, and immune-modulatory ayurvedic formulation can be used for combating flu like illnesses and also in the management of COVID-19 as an adjuvant. However, rigorous double blind randomized controlled trials with larger sample size are warranted for better validation in such clinical conditions.


2011 ◽  
Vol 2 (1) ◽  
pp. 15-19
Author(s):  
Cipta Ginting ◽  
Dad R.J. Sembodo ◽  
Herry Susanto

The efficacy of plant powder to control foot rot on black pepper in field condition. One of the problems in cultivating black pepper (Piper nigrum L.) is foot rot caused by Phytophthora capsici Leonian (P. palmivora MF4), that could kill the plants in only few days especially during rainy season.  The objective of this experiment was to evaluate the efficacy of several plant powder to control the disease in semi-field condition.  The experiment was conducted at the experiment station located at the campus of the University of Lampung from May to October of 2000.  The semi-field condition was made by pushing a barrel into the soil to isolate the field soil as testing medium from the rest of the field soil.  The treatments were arranged in a randomized complete block design with five replications and consisted of the rhizomes of Zingiber officinale, Alpinia galanga, and Kaempferia galanga, whole plant of Cymbopogon citratus and Elephantopus scaber, metalaxyl, and untreated control.  To prepare the plant powder, each material was cut into small pieces then dried in oven at 50o C for 4 days and then ground in a blender.  The powder was applied 3 days after inoculum infestation.  The powder and inoculum was mixed with soil to the depth of 12 cm so that the soil contained 2% each.  After one week, four plants were planted.  As additional bioindicator to detect infective inoculum, eight leaf portions were pressed into the soil so that half of the leaf was bellowed the soil line.  The plants were watered and observed daily.  To determine viable fungal propagules, soil sample was taken weekly for five weeks.  Soil assay was done with dilution technique using PDA supplemented with rosebengal.  The results of the observation show that the treatments did not influence significantly the disease intensity on leaf portions or the whole plants.  There were no significant differences on viable fungal propagules in soils received different treatments.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Philip Adeyemi Adeniyi

Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis.


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