scholarly journals Successful control of Johne's disease in nine dairy herds: Results of a six-year field trial

2010 ◽  
Vol 93 (4) ◽  
pp. 1638-1643 ◽  
Author(s):  
M.T. Collins ◽  
V. Eggleston ◽  
E.J.B. Manning
Keyword(s):  
Field Trial ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Dairy Herds ◽  
Successful Control

scholarly journals Effectiveness and Economic Viability of Johne's Disease (Paratuberculosis) Control Practices in Dairy Herds

2021 ◽  
Vol 7 ◽  
Author(s):  
Philip Rasmussen ◽  
Herman W. Barkema ◽  
David C. Hall
Keyword(s):  
Johne's Disease ◽  
Johne’S Disease ◽  
Dairy Herds ◽  
Dual Effect ◽  
Control Programs ◽  
Control Practice ◽  
Potential Control ◽  
Almost All ◽  
Selection Of ◽  
Promising Type

Johne's disease (JD or paratuberculosis) control programs have been established in many dairy-producing regions. However, the effectiveness (reduction of within-herd prevalence) and the relative economic impact as measured by, for example, the ratio of benefits to costs (BCR) across a comprehensive selection of regions and potential control practices require further investigation. Within a Markovian framework using region-specific economic variables, it was estimated that vaccination was the most promising type of JD control practice modeled, with dual-effect vaccines (reducing shedding and providing protective immunity) having BCRs between 1.48 and 2.13 in Canada, with a break-even period of between 6.17 and 7.61 years. Dual-effect vaccines were also estimated to yield BCRs greater than one in almost all major dairy-producing regions, with greater ratios in regions characterized by above-average farm-gate prices and annual production per cow. Testing and culling was comparably effective to a dual-effect vaccine at test sensitivities >70% but would remain economically unviable in almost all regions modeled.

scholarly journals Mycobacterium Avium Paratuberculosis: A Disease Burden on the Dairy Industry

Animals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1773
Author(s):  
Mary Garvey
Keyword(s):  
Economic Impact ◽  
Mycobacterium Avium ◽  
Dairy Industry ◽  
Latency Period ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Control Measures ◽  
Dairy Herds ◽  
Infectious Dose ◽  
Mycobacterium Avium Paratuberculosis

Mycobacterium avium paratuberculosis is responsible for paratuberculosis or Johne’s disease in cows, having economic impacts on the dairy industry and a prevalence rate exceeding 50% in dairy herds. The economic burden of Johne’s disease relates to decreased milk production and costs of disease prevention, treatment, and management, while having an economic impact on dairy producers, processors, consumers, and stakeholders of the dairy industry. Determining the true economic impact of the disease is difficult at regional and farm level as symptoms are not evident in subclinically infected animals. At present, the virulence, pathogenicity, persistence, and infectious dose of M. avium paratuberculosis are poorly understood, consequently effective paratuberculosis control measures remain obscure. M. avium paratuberculosis is potentially zoonotic with foodborne transmission a public health risk due to a possible causative link with inflammatory bowel disease in humans. A preventive approach is necessary to reduce the presence of this drug-resistant pathogen in dairy herds and subsequently dairy food. The use of inefficient diagnostic tests coupled with the long latency period of infection results in delayed animal culling and trade of asymptomatic animals, leading to regional transmission and increased disease prevalence. To date, there has been limited success at controlling and treating this terminal endemic disease, leading to significant prevalence rates. This study aims to outline the key factors associated with Johne’s’ disease while outlining its significant impact on the dairy sector.

Johne's Disease

1989 ◽  
Keyword(s):  
Health Problem ◽  
Animal Health ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Economic Losses ◽  
Dairy Herds ◽  
Southern States ◽  
Management Diagnosis

Johne's disease (paratuberculosis) afflicts cattle worldwide and causes significant economic losses. It is also prevalent in goats and sheep and has been implicated in Johne's disease in humans. The book is divided into six sections covering all aspects of the prevalence, management, diagnosis, control and research on Johne's disease. ]ohne's disease is an international animal health problem, and is of particular importance in the southern States of Australia, especially in the major dairy areas of Victoria where approximately 10% of dairy herds are infected.

scholarly journals Control of Johne's Disease in Four Commercial Dairy Herds in Iowa

1989 ◽  
Vol 1 (3) ◽  
pp. 223-226 ◽  
Author(s):  
Charles O. Thoen ◽  
Larry A. Moore
Keyword(s):  
Potassium Chloride ◽  
Milk Production ◽  
Market Value ◽  
Control Program ◽  
Johne's Disease ◽  
Johne’S Disease ◽  
Economic Losses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Dairy Herds ◽  
Serum Samples

A 6-year study was conducted in 4 dairy herds in Iowa in which Johne's disease was diagnosed previously. Fecal specimens were collected at 6-month intervals from animals 2 years of age and over for mycobacteriologic examination. Serum samples were obtained at 3-month intervals and tested by enzyme-linked immunosorbent assay (ELISA). The antigen used in the ELISA was a potassium chloride extract of a field strain of Mycobacterium paratuberculosis. The ELISA reactions were observed in 87% of the cows from which M. paratuberculosis was isolated. Dairy producers that participated in the Johne's control program reported reduced economic losses. Increased income was attributed to improved milk production, increased value of vaccinated animals sold as replacements to other dairy herds in which Johne's disease had been diagnosed, and the increased market value of slaughter animals removed from the herd.

scholarly journals Within-herd prevalence thresholds for the detection of Mycobacterium avium subspecies paratuberculosis-positive dairy herds using boot swabs and liquid manure samples

2015 ◽  
Vol 144 (2) ◽  
pp. 413-424 ◽  
Author(s):  
K. DONAT ◽  
N. HAHN ◽  
T. EISENBERG ◽  
K. SCHLEZ ◽  
H. KÖHLER ◽  
...  
Keyword(s):  
Mycobacterium Avium ◽  
Mycobacterium Avium Subspecies Paratuberculosis ◽  
Threshold Level ◽  
Johne's Disease ◽  
Probability Of Detection ◽  
Johne’S Disease ◽  
Dairy Herds ◽  
Liquid Manure ◽  
Herd Prevalence ◽  
Faecal Culture

SUMMARYThe control of Johne's disease requires the identification of Mycobacterium avium ssp. paratuberculosis (MAP)-positive herds. Boot swabs and liquid manure samples have been suggested as an easy-to-use alternative to sampling individual animals in order to diagnose subclinical Johne's disease at the herd level, but there is a need to evaluate performance of this approach in the field. Using a logistic regression model, this study aimed to calculate the threshold level of the apparent within-herd prevalence as determined by individual faecal culture, thus allowing the detection of whether a herd is MAP positive. A total of 77 boot swabs and 75 liquid manure samples were taken from 19 certified negative and 58 positive dairy herds. Faecal culture, three different polymerase chain reaction (PCR) methods and the combination of faecal culture with PCR were applied in order to detect MAP. For 50% probability of detection, a within-herd prevalence threshold of 1·5% was calculated for testing both matrices simultaneously by faecal culture and PCR, with the threshold increased to 4·0% for 90% probability of detection. The results encourage the use of boot swabs or liquid manure samples, or a combination both, for identifying MAP-positive herds and, to a certain extent, for monitoring certified Johne's disease-negative cattle herds.

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