scholarly journals The Correlation of Mammary Gland Development of Heifers with Their Body Weight and the Milk Production of Their Dams

1953 ◽  
Vol 36 (10) ◽  
pp. 1058-1062 ◽  
Author(s):  
Donald S. Cross ◽  
C.B. Knodt
1955 ◽  
Vol 46 (2) ◽  
pp. 137-142 ◽  
Author(s):  
E. S. E. Hafez

Thirty-five buffalo heifers were tested daily with fertile males to ascertain the age and live weight at first possible oestrus and conception. Patterns of sexual behaviour were recorded while rectal palpation was carried out to define the conditions of the ovaries and to diagnose pregnancies. The mammary gland development, as well as the intensity of lactation, were noted post partum.1. Pubertal matings were allowed with less certainty than adult matings. The signs of oestrus were intensified by the recurrence of heat and association with the male. Homosexuality was only observed in the first and second oestrus.2. The average age of first oestrus, first conception and first calving were 406, 647 and 963 days respectively. The body weight at first oestrus and first conception were 198 and 319 kg. respectively.3. The number of services/conception ranged from 1 to 7 with an average of 4·25. The number of silent heats/female ranged from 1 to 4 with an average of 1·65. The period elapsing from first oestrus to first conception ranged from 52 to 438 days. Before conception, there was a period of anoestrus which ranged from 115 to 314 days, this was probably due to weak oestrus symptoms.4. The live weights at 28, 84, 140, 196, 252 and 308 days were correlated with the age and live weight at first oestrus as well as the live weight at first conception.5. All the buffalo-cows except two which showed oestrus conceived. Fourteen animals calved normally while fourteen aborted after 131–318 days. The gestation period ranged from 312 to 321 days with an average of 316 days. The birth weight of young ranged from 33 to 40 kg. Seven animals were not lactating while seven gave 1–2 kg. of milk.6. Puberty phenomenon is a gradual phenomenon and is attained in steps: sexual desire, ovulation, oestrus, conception, pregnancy then lactation.


2020 ◽  
Author(s):  
Yao Xiao ◽  
Jason M. Kronenfeld ◽  
Benjamin J. Renquist

ABSTRACTWith a growing population, a reliable food supply is increasingly important. Heat stress reduces livestock meat and milk production. Genetic selection of high producing animals increases endogenous heat production, while climate change increases exogenous heat exposure. Both sources of heat exacerbate the risk of heat-induced depression of production. Rodents are valuable models to understand mechanisms conserved across species. Heat exposure suppresses feed intake across homeothermic species including rodents and production animal species. We assessed the response to early-mid lactation or late gestation heat exposure on milk production and mammary gland development/function, respectively. Using pair-fed controls we experimentally isolated the food intake dependent and independent effects of heat stress on mammary function and mass. Heat exposure (35°C, relative humidity 50%) decreased daily food intake. When heat exposure occurred during lactation, hypophagia accounted for approximately 50% of the heat stress induced hypogalactia. Heat exposure during middle to late gestation suppressed food intake, which was fully responsible for the lowered mammary gland weight of dams at parturition. However, the impaired mammary gland function in heat exposed dams measured by metabolic rate and lactogenesis could not be explained by depressed food consumption. In conclusion, mice recapitulate the depressed milk production and mammary gland development observed in dairy species while providing insight regarding the role of food intake. This opens the potential to apply genetic, experimental and pharmacological models unique to mice to identify the mechanism by which heat is limiting animal production.Summary StatementsThis study demonstrates that heat stress decreases lactation and mammary development through food intake dependent and independent mechanisms.


2018 ◽  
Vol 18 (4) ◽  
pp. 973-990 ◽  
Author(s):  
Hoda Javaheri Barfourooshi ◽  
Armin Towhidi ◽  
Hassan Sadeghipanah ◽  
Mahdi Zhandi ◽  
Saeed Zeinoaldini ◽  
...  

AbstractThe aim of this study was to evaluate the effect of feeding oil supplement on mammary gland development and milk production responses in Holstein cows. Ten multiparous Holstein cows (42.2±9.2 d before calving, 3.25±0.25 body condition score, and 620±35 kg body weight) were randomly assigned to treatments. Treatments were a diet with oil added as palm oil (PO; n=5), or fish oil (FO; n=5) given to cows until 63 d in milk. Milk yield was recorded daily, milk composition (fat, protein, lactose, total solid and somatic cell count) was measured weekly and fatty acid profiles of milk fat were determined at first and last week of the experiment. Samples of mammary tissue were obtained at 7 and 63 d in milk by biopsy gun. Tissue slides were analyzed by Image J software. Results showed that fish oil supplemented diet compared to the palm oil supplemented diet increased milk production after 6 weeks of lactation (P<0.05), content of polyunsaturated fatty acids milk fat (P<0.05) and docosahexaenoic acid (P<0.01). Moreover, n-6:n-3 ratio was decreased by fish oil supplement (P<0.05). Histological studies showed that FO increased the relative percentage of tissue area occupied by epithelial cells as well as a number of total alveoli in each microscopic field (P<0.05). Data suggested that feeding fish oil during the dry period and early lactation could improve development and function of the mammary gland in the dairy cow.


2018 ◽  
Vol 239 (2) ◽  
pp. 121-136 ◽  
Author(s):  
Dan Li ◽  
Yan Ji ◽  
Chunlan Zhao ◽  
Yapeng Yao ◽  
Anlan Yang ◽  
...  

Oxytocin receptor (OXTR) is a G-protein-coupled receptor and known for regulation of maternal and social behaviors. Null mutation (Oxtr−/−) leads to defects in lactation due to impaired milk ejection and maternal nurturing. Overexpression of OXTR has never been studied. To define the functions of OXTR overexpression, a transgenic mouse model that overexpresses mouse Oxtr under β-actin promoter was developed ( ++ Oxtr). ++ Oxtr mice displayed advanced development and maturation of mammary gland, including ductal distention, enhanced secretory differentiation and early milk production at non-pregnancy and early pregnancy. However, ++ Oxtr dams failed to produce adequate amount of milk and led to lethality of newborns due to early involution of mammary gland in lactation. Mammary gland transplantation results indicated the abnormal mammary gland development was mainly from hormonal changes in ++Oxtr mice but not from OXTR overexpression in mammary gland. Elevated OXTR expression increased prolactin-induced phosphorylation and nuclear localization of STAT5 (p-STAT5), and decreased progesterone level, leading to early milk production in non-pregnant and early pregnant females, whereas low prolactin and STAT5 activation in lactation led to insufficient milk production. Progesterone treatment reversed the OXTR-induced accelerated mammary gland development by inhibition of prolactin/p-STAT5 pathway. Prolactin administration rescued lactation deficiency through STAT5 activation. Progesterone plays a negative role in OXTR-regulated prolactin/p-STAT5 pathways. The study provides evidence that OXTR overexpression induces abnormal mammary gland development through progesterone and prolactin-regulated p-STAT5 pathway.


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