scholarly journals THE FEATURES OF SURGICAL TREATMENT AND MORPHOLOGICAL ASPECTS OF EPULIS AND PAPILLOMA IN CHILDREN

2021 ◽  
pp. 28-37
Author(s):  
P.I. Tkachenko ◽  
I.I. Starchenko ◽  
S.O. Bilokon ◽  
N.M. Lokhmatova ◽  
O.B. Dolenko ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Giant Cell ◽  
Clinical Diagnosis ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Morphological Structure ◽  
Final Diagnosis ◽  
Histological Structure ◽  
Surgical Removal ◽  
Time Periods

The paper presents the findings of the study on the features of surgical treatment and morphological structure of epulis and papillomas in children. The clinical aspect of the paper concerns 123 children with epulis and 185 with papillomas, who were treated at the clinic of the Department of Pediatric Oral Surgery for the period of 10 years. Verification of the histological structure of neoplasms to determine the final diagnosis was performed by the faculty staff of the Department of Pathological Anatomy with Autopsy Course. Statistical processing of the digital data and analysis of the findings of the study showed that epulis and papillomas are more common in girls than in boys (in 2.5 and 2.3 times higher, respectively). A clear pattern of their diagnosis by age was established. Thus, the peak incidence of epulis was recorded in young adolescents of lower and higher secondary school ages (60.3% and 36.6%, respectively). Papilloma was also found quite often in the same age groups (47.0% and 31.4%, respectively). After comprehensive examination, the clinical diagnosis of the giant cell epulis was established in 21.1% of cases, and the share of its fibrous and angiomatous forms accounted for 35.0% and 43.9%, respectively. Neither patients with epulis of all its types nor their relatives could clearly determine the time periods of the appearance of the first clinical signs of the disease. All patients with papillomas and their relatives complained of the presence of newly formed masses on the oral mucosa or skin, which caused some discomfort, growing slowly, rarely reaching large sizes. The exact time periods of their occurrence could not be specified. Treatment of epulis, provided outpatiently for all patients under local anesthesia, was aimed at elimination of the etiological factor (if detected) and surgery. No recurrences were noted after removal of fibrous epulis and in cases of treatment of angiomatous epulis recurrence occurred in 1 girl. Among patients with giant cell epulis, recurrence after surgical removal was observed in 4 patients, 3 of whom underwent repeated surgery with preservation of teeth. In 1 child recurrence occurred for the third time and tooth extraction and partial resection of the alveolar ridge was made as part of the inpatient treatment. Treatment of papillomas involved surgical removal of neoplasms at the border of healthy tissue up to the submucosal layer using an electrocoagulator or radio knife. Depending on the clinical situation and localization of the tumor, manipulations were performed under local (161 cases - 87.0%) anesthesia at the polyclinic, and in 24 children (13.0%) with labile mental health and localization of papilloma on the soft palate, uvula, palatal arches, anesthesia was performed at inpatient. No complications during surgery and in the postoperative period were observed. The surgical material was always sent for histological examination, the results of which allowed determining one of the mentioned nosological forms. Morphological study has established, that the clinical diagnosis did not coincide with the morphological one in 5 cases (4.1%) in fibrous epulis, in 8 - 6.5% in angiomatous and in 10 - 8.1% in giant cell forms, which together made their discrepancy in 23 observations (18.7%). Thus, epulis and papillomas located in the oral cavity have a certain similarity in clinical symptoms and require careful differential diagnosis, and given their unique morphological structure, the final diagnosis must be established taking into account the findings of histopathological examination, as inconsistency of clinical and histopathological examinations, for example, in epulis, reaches 18.7%. When planning the treatment, in an every single case the type, extent and site of surgery, as well as type of anesthesia should be carefully considered. The presented material can serve as the basis for further in-depth scientific and practical research on comparison of clinical manifestations and immunohistochemical features of epulis and papillomas depending the age of patients.

scholarly journals Primary Paranasal Maxillary Hematoma: Clinical Characteristics, Diagnosis and Surgical Treatment

2019 ◽  
Vol 47 ◽  
Author(s):  
Natalia Franco De Oliveira e Oliveira ◽  
Murilo Martinez Matheus ◽  
Fernando Mosquera Jaramilo ◽  
Maurício José Bittar ◽  
José Carlos Guilarde Pacheco ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Nasal Cavity ◽  
Paranasal Sinus ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Definitive Diagnosis ◽  
Surgical Removal ◽  
Adequate Treatment ◽  
Complex Anatomy ◽  
The Right

Background: The equine paranasal sinus have a complex anatomy and large compartiments. For this reason, deseases that affect these structures may develop for long periods before the animal show any clinical signs, making it difficult to stablish a definitive diagnosis and institute an adequate treatment.  Usually, maxillary hematomas reports come from progression of ethmoidal hematomas, and the descriptions of primary maxillary hematomas are rare. This study aims to report the clinical features, diagnosis and treatment of a case of a maxillary hematoma not associated with ethmoidal turbinates.Case: An 8-year-old male horse, Mangalarga Paulista, was referred to the Centro de Apoio ao Ensino e Pesquisa FMVZ-USP with history of nasal bleeding for over a year. The animal presented deformity on the right side of the face, with significant volume increase on the maxillary bone region and dull sound at percussion, in addition to great painfull sensibility when palpated. The right nare had no airflow, suggesting complete obstruction of the right nasal cavity. In order to better evaluate, endoscopic and radiographic exams were performed. At the radiographic exam, in ventrodorsal projection, it was observed an increase of volume and radiopacity, occupying the right antimer of the nasal cavity, with left nasal septum deviation. In the right dorsoventral oblique projection, it was observed the filling of the rostral and caudal maxillary sinus with the content radiopacity as previously described. At endoscopy exam of the right nasal cavity, it was observed a rounded greenish structure on the middle meatus The diagnosis of maxillary paranasal sinus cist was suggested and surgical removal, through maxillary sinusotomy was recommended. During the surgical procedure, it was noted that the structure previously observed, was not a cavitary organization filled with liquid, but a deorganized, dark and friable mass, like a hematoma.   A fragment was sent to histopathological evaluation, which revealed the presence of intact eythrocytes interspersed by fibrilar eosinophilic material (fibrin). There were no indications of an infectious or neoplastic process. The diagnosis of maxillary hematoma was concluded. Forty days after admission, the patient had no surgical complications and showed adequate respiratory flow, at which point the animal was discharged.Discussion: Primary maxillary hematomas are rare on equines. Although benign, it has destructives and expansives characteristics, and for this reason, it can be confused with malignant tumor formation. It has unknown ethiology, and the clinical signs observed are diverse and non specific, which makes it hard to stablish a definitive diagnosis based only on the clinical manifestations of the animal. In this particular case presented, the diagnosis was defined from the hitophatological examination. Initially the image exams (radiography and endoscopy) were usefull to stablish differential diagnosis, as well as the extention of the sinus mass. The surgery was performed with the animal on quadrupedal position, under sedation and local anethesia, in order to dimish haemorrhage occurance during the procedure. This paper describes a primary maxillary hematoma on a horse, characterizing it as to the clinical and pathological manifestations, as well as its surgical treatment. Although rare descriptions and with non specific clinical signs, it is suggested that its occurrence is superior to that described in the literature.   

scholarly journals The Frequency and Causes of Subepidermal Gaps or Blisters and the Compliance Rate Between Clinical Diagnosis and Pathology Reports from 2015 to 2019

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Abbas Darjani ◽  
Hojat Eftekhari ◽  
Seyedeh Rojin Amini Rad ◽  
Narges Alizadeh ◽  
Rana Rafiee ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Skin Diseases ◽  
Histopathological Examination ◽  
Compliance Rate ◽  
Clinical Manifestations ◽  
Final Diagnosis ◽  
Direct Immunofluorescence ◽  
Diagnostic Challenge ◽  
Cross Sectional ◽  
Pathology Reports

Background: Skin diseases are the fourth most common cause of human illness, and blisters with different clinical manifestations make a diagnostic challenge. Objectives: This study aimed to evaluate the frequency and causes of subepidermal gaps or blisters, as well as the compliance rate between the initial and final clinical diagnoses based on pathology reports. Methods: In this cross-sectional study, pathology reports of subepidermal blisters or gaps were evaluated in the patients referred to the Razi Laboratory of Rasht from 2015 to 2019. The samples were examined by a pathologist after hematoxylin and eosin staining. The reports included demographic information, clinical differential diagnoses, final diagnosis, direct immunofluorescence findings, and salt split results. Finally, the compliance rate of clinical diagnosis with pathology reports was determined. Results: A total of 183 pathology reports were evaluated, 170 of which contained the final diagnosis. Females were more frequently affected by the disease, and pemphigoid bolus and lichen planus were the most prevalent final diagnoses. The compliance rate between the initial and final diagnoses was 94%. About 37.2% of the reports lacked direct immunofluorescence (DIF) and salt split, and only 42.6% of the samples had undergone DIF examination, while 20.2% had both DIF and salt split. There was no significant association between the compliance rate of the final diagnosis with age, sex, and undergoing diagnostic tests. Conclusions: A high incidence of subepidermal gaps or blisters was seen in middle-aged individuals and females. The compliance rate of the initial clinical diagnosis with the final diagnosis based on pathological reports was high. Our findings emphasize the importance of histopathological examination and the complementary role of direct immunofluorescence and salt split in diagnosis.

scholarly journals Case report of the successful removal of a haemangioma of the left ventricle in a paediatric patient

2020 ◽  
Vol 24 (3) ◽  
pp. 132
Author(s):  
U. G. Kolbik ◽  
A. V. Gorustovich ◽  
Yu. I. Linnik ◽  
M. M. Shved ◽  
V. V. Drozdovskaya ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Paediatric Patient ◽  
Conflict Of Interest ◽  
Recovery Period ◽  
Final Diagnosis ◽  
Surgical Removal ◽  
Capillary Haemangioma ◽  
Cardiac Tumours ◽  
Post Surgery ◽  
Choice Of Treatment

<p>This publication presents the clinical observation in a paediatric patient with haemangioma of the left stomach. The effectiveness of surgical treatment of this disease is also noted. We assess the challenges in diagnosis and the choice of treatment of this pathology in children and the effectiveness of surgical treatment disease.<br />Primary cardiac tumours are rare; vascular tumours and haemangiomas are rarer. The clinical picture of heart haemangioma is non-specific and varies as per its location and size. Echocardiography is the main diagnostic method for this disease. However, in most cases of preoperative diagnostic examination, the pre-surgery diagnosis is not confirmed. The final diagnosis of capillary haemangioma is established following immunohistochemical staining of the surgical material. Thus far, owing to the rare occurrence, a generally accepted tactic for the treatment of such patients with vascular heart tumours has not been developed.<br />This clinical case describes our experience of treating a rare pathology in children with unusual localisation as well as the rapid successful surgical removal of the tumour without complications and with a favourable post-surgery recovery period.</p><p>Received 14 May 2020. Revised 15 June 2020. Accepted 26 June 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong> <br />Literature review: U.G. Kolbik, A.V. Gorustovich, Y.I. Linnik<br />Illustrations: U.G. Kolbik, I.V. Sakharov, V.V. Drozdovskaya <br />Drafting the article: U.G. Kolbik, A.V. Gorustovich, I.V. Sakharov<br />Critical revision of the article: I.V. Sakharov, M.M. Shved, Yu.I. Linnik<br />Surgical treatment: A.V. Gorustovich, M.M. Shved, U.G. Kolbik<br />Final approval of the version to be published: U.G. Kolbik, A.V. Gorustovich, Yu.I. Linnik, M.M. Shved, V.V. Drozdovskaya, <br />I.V. Sakharov, K.V. Drozdovski</p>

scholarly journals SYNDROME OF THE FIRST GILL ARCH IN A NEWBORN CHILD (CLINICAL CASE)

2020 ◽  
Vol 20 (4) ◽  
pp. 237-240
Author(s):  
M. Yе. Fesenko ◽  
O. A. Scherban ◽  
M. M. Fastovets ◽  
O.O. Kalyuzhka ◽  
Yu. I. Chernyavska
Keyword(s):  
At Risk ◽  
Clinical Case ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Facial Asymmetry ◽  
Final Diagnosis ◽  
Gill Arch ◽  
Dynamic Monitoring ◽  
Large Variability ◽  
Neuropsychological Development

The article describes a clinical case of “First Gill Arch Syndrome" in a newborn girl, the peculiarities of the syndrome, its diagnosis. The characteristics of this disease is that the mother of the child was at risk group due to smoking, anaemia during the pregnancy and medical abortions in the past obstetric history. The aetiology of "First Gill Arch Syndrome" is insufficiently studied, but, according to latest concepts, this condition results from the mutations in the TCOF1 gene. The aetiology of the disease also does not exclude the role of adverse obstetric and gynaecological anamnesis and diseases of the mother, previous medical abortions and teratogenic factors. Difficulties in diagnosis are due to the large variability of clinical manifestations and course of the disease. The final diagnosis of the child was based on specific clinical signs of the disease: facial asymmetry, unilateral facial paralysis (lesions of the facial nerve on the right), the presence of blind fistula of the left cheek and skin suspension of the left auricle. We can conclude about the necessity to elaborate preventive measures to reduce the occurrence of this disease: timely ultrasound examination of pregnant women, who are at risk and mandatory dynamic monitoring of a child with this disease to assess physical and neuropsychological development.

Characteristics of clinical manifestations of Marfan syndrome in childrenand complications of surgical treatment of lens luxation

2013 ◽  
Vol 4 (1) ◽  
pp. 58-61
Author(s):  
Arofat Ziyavutdinovna Toshpulatova
Keyword(s):  
Surgical Treatment ◽  
Postoperative Complications ◽  
Marfan Syndrome ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Secondary Glaucoma ◽  
Traditional Methods ◽  
Ocular Manifestations ◽  
Lens Luxation

The most common ocular clinical signs of Marfan syndrome are lens luxation (46.16 %) and cataract (26.92 %), which during their progression are complicated by secondary glaucoma, lenticular myopia and strabismus. Discussed information indicates to the need to improve the traditional methods of surgery in children with ocular manifestations of Marfan syndrome in order to reduce the risk of intraand postoperative complications.

scholarly journals Diagnosis and surgical treatment of heart valve non-mixoma tumors

2014 ◽  
Vol 95 (6) ◽  
pp. 821-830 ◽  
Author(s):  
A Yu Kiprenskiy ◽  
M A Nechayenko ◽  
L M Kuznetsova ◽  
D N Fyodorov
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Heart Valves ◽  
Heart Defects ◽  
Artery Bypass ◽  
Clinical Signs ◽  
Diagnostic Procedures ◽  
Surgical Removal ◽  
Primary Tumors

Aim. To study the clinical, diagnostic, surgical and morphological features of non-mixoma primary tumors of the heart valves, the possibilities of their early diagnosis and to develop an optimal surgical approach. Methods. The surgical treatment of 331 patients with tumors of the heart was analysed, of which 45 (13.6%) were radically distant primary tumors of the heart valves including 33 (73.3%) myxoma and 12 (26.7%) non-myxoma tumors. Among considered in this study 12 non-myxoma tumors 9 cases were papillary fibroelastoma, 1 - neurolemmoma, 1 - lipoma, 1 - fibroma. Results. The leading non-invasive preoperative diagnostic procedures for non-myxoma primary tumors of the heart valves were transthoracic and transoesophageal echocardiographic studies, the sensitivity of which were 91.7 and 100% respectively. In unclear cases, a computer and magnetic resonance imaging were used. Additionally, electrocardiography, phonocardiography, radiological methods were performed, clinical and biochemical blood tests were analysed. Intraoperative revision and morphological verification ensures the establishment of tumors final clinical diagnosis. Patients with non-myxoma tumors of the heart valves had polymorphic symptomatic picture which included circulatory failure, false angina, arrhythmias, clinical signs imitating heart defects, embolic syndrome, dizziness and/or syncope, causeless fever. Surgical removal of the 12 non-myxoma tumor was performed by cardiopulmonary bypass and pharmacological cold cardioplegia, in 4 cases, the intervention combined with the replacement of the affected valves by artificial prostheses, in 1 case - coronary artery bypass grafting. Hospital mortality of patients was zero. Quality of life of operated patients was rated as good in 9 (75%) patients, satisfactory - in 2 (16.7%), unsatisfactory - in 1 (8.3%) patients, which was due to the death of the patient 13 months after removal of neurolemmoma in connection with multiple metastasis in the brain and spinal cord. Conclusion. Timely surgical intervention helped to stabilize the functional state of the patients, to create a favorable prognosis to improve the quality of life and increase its length.

scholarly journals DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER

2019 ◽  
pp. 92-98
Author(s):  
T. V. Vavilova ◽  
L. A. Isaeva ◽  
K. Yu. Grinchenko ◽  
Ju. D. Bogatenkova ◽  
V. A. Sorokoumov
Keyword(s):  
Antiphospholipid Syndrome ◽  
Laboratory Tests ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Final Diagnosis ◽  
Diagnostic Process ◽  
Clinical Criteria ◽  
Laboratory Confirmation ◽  
Diagnostic Center ◽  
Open Question

Antiphospholipid syndrome (APS) is an immune-mediated violation of coagulation, the diagnosis of which requires mandatory laboratory confirmation. Since the clinical manifestations of APS are extremely diverse, various specialists are involved in the diagnostic process – neurology, cardiologists, surgeons, hematologists, endocrinologists, laboratory medicine specialists, etc. So far, it remains an open question what specialist exactly should make the final diagnosis and supervise patient with APS. The experience of a separate diagnostic center shows the distribution of prescriptions and their compliance with the international recommendations. This study also provides data on the frequency of prescribing laboratory tests to confirm APS, which is 1.2% of all coagulation tests. Among the patients with suspected APS on the basis of clinical signs, only 12.2% of the diagnosis was confirmed. Presents the dangers of obtaining false-positive results that should be taken into account when prescribing laboratory tests.

scholarly journals Peritoneal simple mesothelial cyst: a case report

2019 ◽  
Vol 15 (2) ◽  
pp. 77-80
Author(s):  
Yu. V. Popov ◽  
N. S. Vanke ◽  
A. G. Kedrova
Keyword(s):  
Surgical Treatment ◽  
Clinical Manifestations ◽  
Complete Removal ◽  
Final Diagnosis ◽  
Pathological Examination ◽  
Cystic Formation ◽  
Federal Research ◽  
Clinical Center ◽  
Mesothelial Cyst ◽  
The Right

Primary retroperitoneal cysts are rare benign growths that are often random findings during diagnostic examinations or surgical treatment. The classification, etiology and clinical manifestations of retroperitoneal cysts are the subject of interdisciplinary debate. The most reliable test for their detection is ultrasound and computed tomography. Based on the available literature data, primary cysts of the retroperitoneal space are subject to complete removal within healthy tissues.We present a clinical case of intraoperative detection of a large-sized retroperitoneal cyst in a 42-year-old woman hospitalized in the gynecological department of the Federal Research and Clinical Center for Specialized Medical Care and Medical Technologies, Federal Medical and Biological Agency of the Russian Federation, for surgical treatment of uterine myoma. During the planned surgical treatment revealed the presence of cystic formation of large sizes in the right anterior pararenal space. The final diagnosis was made after a pathological examination. Histologically, the inner epithelial lining of the cystic formation contained multiple ciliary cells, forming papillary structures similar in some areas, with folds of the mucous membrane of the fallopian tube.

scholarly journals Large and giant melanocytic nevi of the maxillofacial area in children: features of the morphological structure and surgical treatment

2015 ◽  
Vol 3 (4) ◽  
pp. 22-28
Author(s):  
Anna Sergeevna Usoltseva ◽  
Yulia Vladimirovna Stepanova ◽  
Ivan Nikolaevich Krasnogorskiy ◽  
Margarita Sergeevna Tsyplakova
Keyword(s):  
Surgical Treatment ◽  
Treatment Options ◽  
Morphological Characteristics ◽  
Morphological Structure ◽  
Melanocytic Nevus ◽  
Surgical Removal ◽  
Congenital Melanocytic Nevus ◽  
Surgical Interventions ◽  
The Face ◽  
Surgical Treatments

Background. Congenital melanocytic nevus is a benign pigmented neoplasm composed of nevus cells that clinically manifest at birth. When choosing a treatment for nevi, the possibility of recurrence as well as the threat of tumor malignancy should be considered. The aim of this work is to justify the surgical removal of a large and giant nevi of the face as a method of treatment justified by the pathomorphological structure. Materials and Methods. In 40 children of different ages born with large and giant nevi of the face, we used various types of plastic surgery to eliminate any defects formed after the excised nevi. We accounted for the features of the maxillofacial area: local plasty, expander dermotension, and transplantation of free skin grafts. We performed a total of 68 surgical interventions. Sixteen patients underwent the surgery once and 24 patients underwent secondary surgery (from 2 to 4). We also developed a scheme of the staged surgical treatments and conservative methods. Results. All patients had stable positive results that were studied by comparing the outcomes of different surgical treatment options and accounting for various morphological characteristics of the removed nevi.

Cholescintigraphy versus Infusion Cholecystography in Acute Cholecystitis

1990 ◽  
Vol 29 (02) ◽  
pp. 51-53
Author(s):  
G. Edlund ◽  
V. Kempi
Keyword(s):  
Acute Cholecystitis ◽  
Clinical Diagnosis ◽  
Random Order ◽  
Final Diagnosis

Patients with the clinical diagnosis of acute cholecystitis were studied with intravenous cholecystography and cholescintigraphy. The two examinations alternated in a random order. The final diagnosis was ascertained by surgery in most patients. Either cholecystography or cholescintigraphy could be used in the diagnostics of patients with suspected acute cholecystitis. The methods have about the same accuracy. However, cholescintigraphy is performed more easily and more rapidly than intravenous cholecystography.

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