scholarly journals Dose Dependent Elevation of Plasma Tocotrienol Levels and Its Effect on Arterial Compliance, Plasma Total Antioxidant Status, and Lipid Profile in Healthy Humans Supplemented with Tocotrienol Rich Vitamin E

2006 ◽  
Vol 52 (6) ◽  
pp. 473-478 ◽  
Author(s):  
Aida H. G. RASOOL ◽  
Kah H. YUEN ◽  
Khalid YUSOFF ◽  
Abdul R. WONG ◽  
Abdul R. A. RAHMAN
2007 ◽  
Vol 61 (1) ◽  
Author(s):  
K. Pawłowska-Góral ◽  
M. Wardas ◽  
P. Wardas ◽  
A. Rzepecka-Stojko

AbstractThe influence of CCl4 on the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), the value of the total antioxidant status (TAS), and the concentration of malonic dialdehyde (MDA) and glutathione (GSH) was monitored in plasma or whole blood of rabbits. The administration of CCl4 caused the increase of the SOD activity to approximately 150 % and the decrease in the activity of GPx and GR by about 50 %. These changes were accompanied with the increase in TAS value and MDA concentration and the decrease of GSH concentration. The effect of CCl4 was suppressed by the previous 7 days lasting or simultaneous administration of vitamin E. Oxidative stress caused by CCl4 was accompanied by the development of reactive oxygen forms, especially superoxide radical anion.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Faridah Hanim Shakirin ◽  
Azrina Azlan ◽  
Amin Ismail ◽  
Zulkhairi Amom ◽  
Lau Cheng Yuon

The aim of this paper was to compare the effects of pulp and kernel oils ofCanarium odontophyllumMiq. (CO) on lipid profile, lipid peroxidation, and oxidative stress of healthy rabbits. The oils are rich in SFAs and MUFAs (mainly palmitic and oleic acids). The pulp oil is rich in polyphenols. Male New Zealand white (NZW) rabbits were fed for 4 weeks on a normal diet containing pulp (NP) or kernel oil (NK) of CO while corn oil was used as control (NC). Total cholesterol (TC), HDL-C, LDL-c and triglycerides (TG) levels were measured in this paper. Antioxidant enzymes (superoxide dismutase and glutathione peroxidise), thiobarbiturate reactive substances (TBARSs), and plasma total antioxidant status (TAS) were also evaluated. Supplementation of CO pulp oil resulted in favorable changes in blood lipid and lipid peroxidation (increased HDL-C, reduced LDL-C, TG, TBARS levels) with enhancement of SOD, GPx, and plasma TAS levels. Meanwhile, supplementation of kernel oil caused lowering of plasma TC and LDL-C as well as enhancement of SOD and TAS levels. These changes showed that oils of CO could be beneficial in improving lipid profile and antioxidant status as when using part of normal diet. The oils can be used as alternative to present vegetable oil.


2010 ◽  
Vol 36 (6) ◽  
pp. 1185-1188 ◽  
Author(s):  
Aysegül Cinkaya ◽  
Hüseyin Levent Keskin ◽  
Umran Buyukkagnici ◽  
Tayfun Gungor ◽  
Esra Aktepe Keskin ◽  
...  

2009 ◽  
Vol 27 (Special Issue 1) ◽  
pp. S236-S240 ◽  
Author(s):  
T. Bojňanská ◽  
H. Frančáková ◽  
P. Chlebo ◽  
A. Vollmannová

The goal of this study is the evaluation of enriched bread prepared with an addition of buckwheat as a source of biologically active components in nutrition. Experimental pastry was baked using buckwheat wholegrain flour blended with wheat flour in different portions (10%, 20%, 30%, 40% and 50%) in order to observe the influence of buckwheat addition on dough processing and the quality of the final baked products. Taking into account the overall acceptability rating, it was concluded that bread with an addition of up to 30% of buckwheat could be baked with satisfactory evaluation results. The content of rutin in loaves in a consumable form prepared with a buckwheat addition varied between 7.76 mg/kg and 26.90 mg/kg. The clinical study which followed the baking experiment was based on the consumption of enriched bread (30% buckwheat, between 34.7 mg/kg and 38.2 mg/kg rutin content in dry matter) by a group of volunteers during a period of four weeks. The results approved the increase of the total antioxidant status thanks to the buckwheat enriched bread consumption from the value of 1.135 ± 0.066 mmol/dm<sup>3</sup> at the beginning of the study to 1.46 ± 0.083 mmol/dm<sup>3</sup> at the end of the study, i.e. significant differences.


2011 ◽  
Vol 35 (4) ◽  
pp. 1064-1067 ◽  
Author(s):  
Xue Feng Li ◽  
You Lan Zheng ◽  
Mei Hong Xiu ◽  
Da Chun Chen ◽  
Thomas R. Kosten ◽  
...  

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