scholarly journals Male Contraceptives: Present and Future Approaches

There is general agreement that men, like women, must take full control of their fertility, an important global health issue. However, the contraceptives for preventing pregnancy that primarily involve male physiology have not changed in the last century. These options are still limited to the non-surgical methods of the use of a condom, abstinence, and a timely withdrawal (coitus interrupts) or the surgical approach of vas occlusion (vasectomy) that prevents sperm from being released during ejaculation. When not defective and used correctly, condoms are effective in preventing unwanted pregnancies as well as providing protection against sexually transmitted diseases. However, condoms, abstinence and timely withdrawal approaches have relatively higher typical-use failure rates whereas vasectomy is largely irreversible and not suitable for younger men. Thus, providing a safe, effective, reversible and affordable contraceptive for men has remained an elusive goal. In this article, we intend to discuss many details of currently available contraceptives for men, the current status of the research and development of non-surgical male contraceptives and also to describe experimental details of three intra-vas approaches that are undergoing advanced clinical trials and may soon be available for men to regulate their fertility. Finally, we will introduce the “sperm switch” approach. This is the latest invention that will allow men to decide if and when to ejaculate spermatozoa during coitus. The availability of several safe, effective, reversible and affordable contraceptives will allow men to take full control of their fertility.

There is general agreement that men, like women, must take full control of their fertility, an important global health issue. However, the contraceptives for preventing pregnancy that primarily involve male physiology have not changed in the last century. These options are still limited to the non-surgical methods of the use of a condom, abstinence, and a timely withdrawal (coitus interrupts) or the surgical approach of vas occlusion (vasectomy) that prevents sperm from being released during ejaculation. When not defective and used correctly, condoms are effective in preventing unwanted pregnancies as well as providing protection against sexually transmitted diseases. However, condoms, abstinence and timely withdrawal approaches have relatively higher typical-use failure rates whereas vasectomy is largely irreversible and not suitable for younger men. Thus, providing a safe, effective, reversible and affordable contraceptive for men has remained an elusive goal. In this article, we intend to discuss many details of currently available contraceptives for men, the current status of the research and development of non-surgical male contraceptives and also to describe experimental details of three intra-vas approaches that are undergoing advanced clinical trials and may soon be available for men to regulate their fertility. Finally, we will introduce the “sperm switch” approach. This is the latest invention that will allow men to decide if and when to ejaculate spermatozoa during coitus. The availability of several safe, effective, reversible and affordable contraceptives will allow men to take full control of their fertility.


Sexual Health ◽  
2015 ◽  
Vol 12 (5) ◽  
pp. 460
Author(s):  
Carole Khaw ◽  
Bin Li ◽  
Russell Waddell

Background With society ageing, sexually transmissible infections (STIs) in the older population are of interest from an economic, health-related and social burden perspective. Few studies on STIs in men older than 60 years of age exist. Methods: A retrospective study was performed looking at characteristics of, and STIs in, 29 106 men (of which 689 were older than 60 years of age), at first presentation, visiting the only South Australian public sexually transmitted diseases (STD) clinic over a 13-year period. Results: Older men [men who have sex with men (MSM) and men who have sex with women (MSW)] were less likely than younger men to have been tested for HIV. Conclusion: There is a need for increased HIV testing in older men.


2015 ◽  
Vol 5 (2) ◽  
pp. 37
Author(s):  
Victor Hugo de Oliveira Henrique ◽  
Edna Lopes Hardoim

A sexualidade compreende aspectos biológicos, psicológicos e socioculturais. Ela é desenvolvida ao longo da vida e inicia-se a partir das primeiras experiências afetivas do bebê. Objetivando compreender o entendimento de sexualidade dos professores de centro de apoio à deficientes auditivos, foi aplicado um questionário semi-estruturado. Todos foram unanimes quanto a importância da temática sexualidade ser trabalhada na escola. Quando questionados se já trabalharam a temática sexualidade em sala de aula a maioria disse que sim, e uma minoria disse que não. Dentro os que responderam abordar a temática em sala de aula, foram relatados os assuntos mais abordados: prevenção de Doenças Sexualmente Transmissíveis e gravidez indesejada, diversidade sexual e de gênero. Os recursos mais usados pelos professores são palestras/oficinas com profissionais da área e filmes/documentários. Percebe-se a necessidade de uma prática interdisciplinar no que toca à sexualidade, e de que todos os profissionais da educação estejam preparados para falar, partindo, ou não, do conteúdo de suas disciplinas.Palavras-chave: Sexualidade; Educação; Professores; Alunos surdos. ABSTRACT: The sexuality includes biological, psychological and sociocultural aspects. It is developed throughout life and starts from the first affective experiences of the baby. Aiming to understand the apprehension of sexuality a questionnaire was applied to teachers of a deaf support center. All were unanimous about the importance of the sexuality be worked at school. When asked if they have worked the theme sexuality in the classroom the majority said yes, and a minority said no. Inside the respondents address the issue in the classroom, the most discussed topics were reported: prevention of sexually transmitted diseases and unwanted pregnancies, sexual and gender diversity. The funds most used by teachers are lectures/workshops with professionals and films/documentaries. We realize the need for an interdisciplinary practice when it comes to sexuality, and that all education professionals are prepared to talk, starting or not the content of their disciplines.Keywords: Sexuality; Education; Teachers; Deaf students.


1997 ◽  
Vol 166 (12) ◽  
pp. 666-666 ◽  
Author(s):  
Sandra C Thompson ◽  
Barbara M Hocking ◽  
Gillian E Checkley ◽  
Nick Crofts ◽  
Anne M Mijch ◽  
...  

Rising threat of the global pandemic COVID 19 has become the major cause of concern among nations worldwide. The appalling pandemic has aggravated the global health of people making normal life come to a virtual standstill. The purpose of this study is to investigate and compare the similarities and differences between the previous global pandemic outbreak SARS-COV-1 with that of COVID 19. It makes use of a bioinformatic approach to analyze why COVID 19 has made situations uncontrollable as opposed to that of SARS-COV-1 although both belong to the same coronavirus family. Discusses about the recent clinical trials that are being conducted to evaluate potential therapeutics to combat the deadly pandemic. There is currently no available vaccine for COVID 19. E The current status of COVID 19 research stands progressive in various areas of knowledge. Further studies based on emerging evidences are required to produce drugs which can slow down disease progression and improve survival.


Vaccines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1026
Author(s):  
Anna Hargrave ◽  
Abu Salim Mustafa ◽  
Asma Hanif ◽  
Javed H. Tunio ◽  
Shumaila Nida M. Hanif

HIV-1 infection and its progression to AIDS remains a significant global health challenge, particularly for low-income countries. Developing a vaccine to prevent HIV-1 infections has proven to be immensely challenging with complex biological acquisition and infection, unforeseen clinical trial disappointments, and funding issues. This paper discusses important landmarks of progress in HIV-1 vaccine development, various vaccine strategies, and clinical trials.


1997 ◽  
Vol 31 (2) ◽  
pp. 285-290 ◽  
Author(s):  
John Coverdale ◽  
Ian Falloon ◽  
Sarah Turbott

Objective: We aimed to determine the attitudes and behaviours of mental health professionals (MHPs) including psychiatrists towards identifying and reducing their own patients' risk for sexually transmitted diseases and unwanted pregnancies. Method: 102 of all of the 162 mental health professionals serving predominantly chronically psychiatrically ill adult outpatients and inpatients in Waitemata district responded to an anonymous questionnaire (response rate = 63%), concerning their own attitudes and behaviours towards identifying and counselling patients on their risk for sexually transmitted diseases and unwanted pregnancies. Results: Mental health professionals reported that, on average, they had counselled 14% of their own male patients and 21% of their own female patients on sexually transmitted diseases, including AIDS prevention, and that more of their own patients were at risk than were counselled. They also reported that they had counselled 5% of their own male patients and 17% of their own female patients about family planning. Forty-two per cent of mental health professionals indicated that they had insufficient knowledge about sexually transmitted diseases to educate patients, 72% indicated that when it came to risky sexual behaviours chronic psychiatric patients were much the same as other people, and 33% or more felt uncomfortable discussing topics of condom use and patients' sexual preferences. Conclusion: These results suggest that family planning and sexually transmitted diseases risk preventive interventions for psychiatric patients need to overcome mental health professionals' own barriers to risk prevention.


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