scholarly journals Squamous Cell Carcinoma of the Lower Lip in an Old Black African Woman

2015 ◽  
Vol 1 (1) ◽  
pp. 34-37
Author(s):  
K. Kassi ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Regional Lymph Node ◽  
Limited Resource ◽  
Surgical Excision ◽  
Functional Results ◽  
African Woman ◽  
Preventive Strategy ◽  
Lower Lip

Squamous cell carcinoma (SCC) of the lower lip is the most frequent cancer of the oral cavity in the elderly. The potential etiologic factors are pipe-smoking, tobacco-chewing and chronic alcohol consumption. They grow slowly and are easily diagnosed. But, they can lead to functional, esthetical complications and to death when diagnosed and treated lately. Here, we report a case of SCC of the lower lip in a black woman aged of 82 year-old evolving for 10 years, associated with tobacco use for over 40 years. The clinical examination noted: a large, bourgeoning and ulcerated tumor covering the 2/3 part of the lower lip with irregular raised indurate borders which bleed when traumatized, without regional lymph node and distant metastasis. The patient was treated by wide surgical excision associated with V to Y advancement flap added to nasolabial island flap, and healed within 4 weeks, with good aesthetic and functional results without any recurrences after 2 years follow up time. The late diagnosis of SCC makes its treatment difficult and expensive in limited resource countries like Côte d’Ivoire. Therefore, it is necessary to set up a preventive strategy to detect the disease in its initial stage to promptly institute effective and efficient care. Keywords: Lip squamous cell carcinoma, Surgical treatment, Local flaps.

scholarly journals Gillies fan flap repair for near total, full thickness defect of lower lip

2018 ◽  
Vol 5 (11) ◽  
pp. 3781
Author(s):  
Beena Aggarwal ◽  
Hitesh Kumar ◽  
Prashant Sharma ◽  
Manish Kaushik ◽  
Saurabh .
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Neck Region ◽  
Surgical Excision ◽  
Cumulative Exposure ◽  
Large Defect ◽  
Lower Lip ◽  
Neurovascular Flap ◽  
Flap Repair

Lip is one of the commonest sites of occurrence of squamous cell carcinoma in head and neck region. 90 % of the cases involve lower lip. Higher cumulative exposure of ultraviolet radiations by sun is an attributed risk factor. A large defect left after surgical excision can be covered by various methods. Myo-neurovascular flap used in Gillies fan flap technique is considered better functionally and aesthetically. We report a 70-year-old gentleman who presented with large carcinomatous growth occupying more than 3/4th of lower lip, only leaving commisures free. Edge wedge biopsy revealed it to be squamous cell carcinoma. Excision of tumor was done along with bilateral supra-omohyoid neck dissection and Gillies fan flap repair. Modified Gillies fan flap repair is one of the various techniques which serves to reconstruct large lower lip defects maintaining the vascularity, nerve supply of lip and gives functional, sensate and aesthetic results

scholarly journals Squamous Cell Carcinoma of the Lower Lip Complicating a Recurrent Labial Herpes During HIV Infection: a Case Report

2020 ◽  
Vol 5 (1) ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Hiv Infection ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Highly Active Antiretroviral Therapy ◽  
Surgical Excision ◽  
Hiv Positive ◽  
Epithelial Tumor ◽  
Lower Lip ◽  
Highly Active

Introduction: Squamous cell carcinoma (SCC) is the main cancer of lips; it is increasingly diagnosed in HIV-positive patients. In most cases, there are factors that promote his occurrence. We report a case of an HIV-positive woman with SCC of the lower lip complicating recurrent labial herpes. Medical observation: It was a case of a 40-year-old female received in consultation for a painful and ulcerous lesion of her lip lasting 5 months. She was a HIV-positive patient diagnose since 2007 and on Highly Active Antiretroviral Therapy since that time. She was taking alcohol, was exposed to sunlight regularly, and had presented many episodes of labial herpes in the past. On clinical examination she had a painful ulcero-crustal medallion measuring 2.5 centimeters in diameter, with a papular edge of pearlescent appearance of the lower lip. Given this clinical picture, the diagnosis of chronic decaying herpes labialis with in differential an epithelial tumor (in particular a squamous cell carcinoma of the lower lip) was mentioned. After surgical excision, an anatomopathological analysis of the part confirmed the diagnosis of squamous cell carcinoma. At the time of diagnosis, the patient had a respective CD4 and CD8 level of 939 and 964 cells / mm3 . The evolution was marked 6 weeks later by the scarring with complete epithelialization of the site of the lesion. Conclusion: SCC of the lips is a frequent cancer occurring during HIV infection; there are many risk factors which promote his occurrence. Earlier the treatment is instituted, better is the prognosis.

scholarly journals Keratinized tumor with aggressive evolution at the orofacial level

2019 ◽  
Vol 2 (1) ◽  
pp. 9-10
Author(s):  
Florica Sandru ◽  
Adelina Popa ◽  
Mihai Dumitrascu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Surgical Excision ◽  
Lower Lip ◽  
Dermatological Examination ◽  
Complete Surgical Excision ◽  
Mandibular Region ◽  
The Right

Squamous cell carcinoma accounts for 90% of the oral cavity carcinomas. Most commonly affects men over 50, smokers. We present the case of a 77-year-old patient diagnosed in our clinic with a rapidly evolutive, highly aggressive squamous cell carcinoma of the lower lip, with aesthetic and functional consequences. The onset of the tumor was at the lower lip and then rapidly spread to the entire surface of the chin. Dermatological examination revealed a suprainfected tumor, adherent to deep structures. The tumor exhibits numerous bumps at the surface, irregular edges, numerous ulcerations and purse bags. The tumor has invasive character, reaching the mandibular bone and was evolving for the last 3 months. The histopathological examinations showed squamous cells, intense nuclear tachycromasia, marked pleomorphism, hight nuclear and cytoplasmic ratio and frequent mitosis, thus being conclusive for the diagnosis of moderately differentiated squamous cel carcinoma. The bacteriological examination revealed bacterial infection with Proteus vulgaris and beta hemolytic Streptococcus. Computer tomography showed the partially necrotic tumor, located on the soft parts of the right mandibular region and submandibular adenopathies. There were no secondary disseminations. This case highlights the need for complete surgical excision of a rapidly evolving tumor with increased size, perineural and perivascular invasion, diagnosed at an early stage where appropriate treatment can be done. 

Reconstruction of a Lower Lip Defect with Bilateral Nasolabial Musculocutaneous Flap. Case Report

2020 ◽  
Vol 25 (3) ◽  
pp. 36-38
Author(s):  
Alina Helgiu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Functional Results ◽  
Radical Excision ◽  
Nasolabial Flap ◽  
Immediate Reconstruction ◽  
Large Defect ◽  
Complete Excision ◽  
Lower Lip

AbstractSquamous cell carcinoma is the most common form of malignant tumour in the lower lip and its radical excision sometimes leads to complex defects. The treatment of squamous cell carcinoma of the lower lip is mainly surgical and consists of complete excision of the tumour, followed by immediate reconstruction. Although the nasolabial flap is a common flap used in the reconstruction of facial defects, it is an underestimated option in the reconstruction of the lower lip. We describe the reconstruction of a large defect of the lower lip that includes the bilateral commissures and ¼ of the upper lip, left side, in a 76-year-old male patient. Bilateral musculocutaneous nasolabial flap was used, with good functional results and an acceptable cosmetic result. We believe that the nasolabial flap is a good alternative for large lip defects both for patients with an affected general condition, but also as an alternative to existing flaps.

Squamous Cell Carcinoma of the External Ear: A Review of 75 Cases

1987 ◽  
Vol 97 (3) ◽  
pp. 308-312 ◽  
Author(s):  
William W. Shockley ◽  
Fred J. Stucker
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cancer Control ◽  
Surgical Excision ◽  
External Ear ◽  
Common Cancer ◽  
Node Metastases

Squamous cell carcinoma of the external ear can be a potentially lethal lesion. Although it is the most common cancer involving the pinna, the variables that have the greatest impact on prognosis are still in question. We reviewed 75 cases of squamous cell carcinoma of the external ear to determine patterns of occurrence and treatment failure. Forty patients had adequate follow-up for determination of cancer control rates. Local control was successful with initial treatment in 85% of the cases. The incidence of lymph node metastases was 10%, whereas distant metastasis occurred in only one patient (2.5%). This series differs from others in that most patients were unselected and most of the lesions treated were early (less than 1 cm). The significance of positive margins after surgical excision is also analyzed.

Efficacy of Different Treatment Modalities for Eye Cancer in Bovines

2021 ◽  
Author(s):  
M. Prasanna Lakshmi ◽  
P. Veena ◽  
R.V. Suresh Kumar ◽  
D. Rani Prameela ◽  
K. Jagan Mohan Reddy
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Dietary Habits ◽  
Growth Factor Receptor ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Treatment Protocols ◽  
Hereditary Factors

Background: Bovine ocular squamous cell carcinoma also called cancer eye, represents the most economically important neoplasm in large animals. Hereditary factors, environmental factors (e.g: latitude, altitude, exposure to sunlight), lack of eyelid pigmentation, age and dietary habits have all been reported to play a role in the etiopathogenesis of bovine ocular squamous cell carcinoma. In addition, in cattle the etiology has been linked to a number of viral agents, especially bovine papilloma virus and bovine herpes virus type 1 and 5. Nevertheless, ultraviolet light, viruses and circumocular pigmentation are the major epidemiologic risk factors for the development of the tumor. The efficacy of different treatment modalities for eye cancer in bovines was studied.Methods: All the animals were divided in to four groups of six animals each. Surgical excision, intra lesion BCG vaccine, surgery with auto vaccine and surgery with mitomycin was the treatment protocols followed. Immunohistochemical studies were conducted to know the rate of proliferation of bovine ye cancer. Immunopositive reaction was observed against Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptor in all the cases.Result: The benefits of different treatment modalities depended on nature, type, location and extensiveness of tumor. Early detection and aggressive treatment were essential in the successful management of these tumors. A multimodal treatment approach was recommended with surgery, immunotherapy and chemotherapy in providing 100% disease free interval.

scholarly journals Occurrence of squamous cell carcinoma in Milchschaf sheep in Uruguay

2017 ◽  
Vol 48 (1) ◽  
Author(s):  
Juan Agustín García ◽  
Carina Quinteros ◽  
Agustín Romero ◽  
Fernando Dutra
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Regional Lymph Node ◽  
Phenotypic Characteristics ◽  
Head Region ◽  
High Prevalence ◽  
Node Metastases ◽  
Main Factors ◽  
Female Sheep

ABSTRACT: In this study, the epidemiological and pathological features of an outbreak of squamous cell carcinoma (SCC) in adult female sheep and a young ram, Friesian Milchschaf breed or crossbreed is described. Seven adult females belonging to an original flock nucleus of 20 animals were affected, as well as a young ram belonging to the same nucleus was affected in other establishment. Multiple verrucous neoplastic masses of several months of evolution were evident in the head region, with local invasion and regional lymph node metastases. Histological studies revealed a cancerous stage of invasion of the dermis and neoplastic proliferation characteristic of invasive SCC, and a pre-cancerous stage with solar elastosis and chronic solar keratosis lesions induced by sunlight. Decrease in latitude, increased level of solar radiation with long exposure to sunlight, and the phenotypic characteristics of the breed are the main factors responsible for the high prevalence of SCC, showing the susceptibility of the Friesian Milchschaf breed and crossbreed in temperate zones as Uruguay.

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