Recent Statistics and Risk Factors of Fentanyl Buccal Tablet Related Opioid Dependence Tendency at a Tertiary Hospital in Korea

The purpose of this study was to identify the risk factors of serious fall-related injuries by analyzing the differences between two fall groups: one with serious fall-related injuries and one without such injuries. Applying a retrospective, descriptive investigation study design, we analyzed the degree of fall-related injury and the risk factors related to serious falls by conducting a complete survey of the medical records of fall patients reported throughout one full year, 2017, at a tertiary hospital in Seoul, Korea. Among the patients with reported falls, 188 sustained no injury (63.1%), 72 sustained minor injury (24.2%), and 38 patients sustained serious injury (12.8%). The serious fall-related injuries included eight lacerations requiring suture (2.7%), 23 fractures (7.7%), five brain injuries (1.7%), and two deaths (0.7%). Analysis results indicated that taking anticoagulants/antiplatelet drugs (p = 0.016) and having a fall history (p = 0.038) were statistically significant in the differences between the group with serious injury related to falls and the group without serious injury. Logistic regression revealed that taking anticoagulant/antiplatelet drugs was the factor most significantly correlated with serious injuries related to falls (OR = 2.299, p = 0.022). Results show that it is necessary to develop a patient-tailored fall prevention activity program.

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745 Risk Factors of Incident Renal Stones in Indian Population: A Hospital-Based Case-Control Study

British Journal of Surgery ◽

10.1093/bjs/znab134.573 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

S Singh ◽

S Gupta ◽

T S Mishra ◽

B D Banerjee ◽

T Sharma ◽

...

Keyword(s):

Risk Factors ◽

Heavy Metals ◽

Case Control Study ◽

Dietary Habits ◽

Renal Stones ◽

Tertiary Hospital ◽

Case Control ◽

The Body ◽

Increased Risk ◽

Control Study

Abstract Introduction Nephrolithiasis is pathological calcification in the excretory passages of the body and is prevalent among 7.6% of Indians. We aimed to study the various risk factors associated with renal stones from India. Method It was a hospital-based case-control study conducted over 18 months in a tertiary hospital in Delhi. Cases were defined as patients with renal stones diagnosed on the basis of history and radiological examination. Controls were similar to cases in all respects except for the diagnosis and selected from the hospital. A total of 18 risk factors, including age, gender, heavy metals, stress, metabolic factors, alcohol intake, dietary habits, co-morbidities, etc. were assessed. Logistic regression analysis was performed to calculate the strength of the risk associations. Results In the analysis of 60 cases and controls, we found 6 times, 5.5 times, and 2.4 times increased odds of renal stones in patients with increased arsenic, cadmium, and lead concentrations in blood, respectively. Similarly, there are 3 times increased odds of renal stones in patients suffering from stress. Conclusions Exposure to smoke, occupation dust, and contaminated water may lead to an increased ingestion/inhalation of heavy metals like cadmium, arsenic, and predisposing people to an increased risk of renal stones.

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The Incidence and Risk Factors of Infusion-Related Reactions to Rituximab for Treating B Cell Malignancies in a Single Tertiary Hospital

Oncology ◽

10.1159/000357711 ◽

2014 ◽

Vol 86 (3) ◽

pp. 127-134 ◽

Cited By ~ 11

Author(s):

Jae-Woo Jung ◽

Hye-Ryun Kang ◽

Se-Hoon Lee ◽

Sang-Heon Cho

Keyword(s):

Risk Factors ◽

B Cell ◽

Tertiary Hospital ◽

B Cell Malignancies

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EffenDys—Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Patients With Advanced Cancer: A Multicenter, Open-Label, Randomized, Morphine-Controlled, Crossover, Phase II Trial

Journal of Pain and Symptom Management ◽

10.1016/j.jpainsymman.2016.05.023 ◽

2016 ◽

Vol 52 (5) ◽

pp. 617-625 ◽

Cited By ~ 13

Author(s):

Steffen T. Simon ◽

Marianne Kloke ◽

Bernd Alt-Epping ◽

Jan Gärtner ◽

Martin Hellmich ◽

...

Keyword(s):

Advanced Cancer ◽

Phase Ii ◽

Phase Ii Trial ◽

Open Label ◽

Fentanyl Buccal Tablet ◽

Buccal Tablet ◽

Crossover Phase

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Absolute and Relative Bioavailability of Fentanyl Buccal Tablet and Oral Transmucosal Fentanyl Citrate

The Journal of Clinical Pharmacology ◽

10.1177/0091270006297749 ◽

2007 ◽

Vol 47 (3) ◽

pp. 343-350 ◽

Cited By ~ 70

Author(s):

Mona Darwish ◽

Mary Kirby ◽

Philmore Robertson ◽

William Tracewell ◽

John G. Jiang

Keyword(s):

Relative Bioavailability ◽

Fentanyl Citrate ◽

Oral Transmucosal Fentanyl Citrate ◽

Fentanyl Buccal Tablet ◽

Buccal Tablet

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Clinical and radiological risk factors for rupture of vertebral artery dissecting aneurysm: significance of the stagnation sign

Journal of Neurosurgery ◽

10.3171/2021.9.jns211848 ◽

2021 ◽

pp. 1-6

Keyword(s):

Risk Factors ◽

Vertebral Artery ◽

Posterior Inferior Cerebellar Artery ◽

Significant Risk ◽

Multivariate Logistic Regression Analysis ◽

Significant Risk Factor ◽

Tertiary Hospital ◽

Dissecting Aneurysm ◽

Irregular Surface ◽

Vertebral Artery Dissecting Aneurysm

OBJECTIVE The aim of this study was to investigate the clinical and radiological factors associated with the rupture of a vertebral artery dissecting aneurysm (VADA) and to evaluate whether the stagnation sign is a significant risk factor for rupture of VADA. METHODS Clinical and radiological variables of 117 VADAs treated in a tertiary hospital from September 2008 to December 2020 were retrospectively reviewed. The stagnation sign is defined as the finding of contrast agent remaining in the lesion until the venous phase of angiography. Univariate and multivariate analyses were executed to reveal the associations between rupture status and VADA characteristics. RESULTS The rate of ruptured VADAs was 29.1% (34 of 117) and the stagnation sign was observed in 39.3% (46 of 117). Fusiform shape (OR 5.105, 95% CI 1.591–16.383, p = 0.006), irregular surface (OR 4.200, 95% CI 1.412–12.495, p = 0.010), posterior inferior cerebellar artery (PICA) involvement (OR 3.788, 95% CI 1.288–11.136, p = 0.016), and the stagnation sign (OR = 3.317, 95% CI 1.131–9.732, p = 0.029) were significantly related to rupture of VADA in multivariate logistic regression analysis. CONCLUSIONS This study showed that fusiform shape, irregular surface, PICA involvement, and the stagnation sign may be independent risk factors for the rupture of VADA. Therefore, when the potential risk factors are observed in unruptured VADA, more aggressive treatment rather than follow-up or medical therapy may be considered.

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