scholarly journals A CLINICAL COMPARATIVE STUDY BETWEEN MISOPROSTOL (PGE1) AND DINOPROSTONE (PGE2) FOR INDUCTION OF LABOUR AT TERM - A PROSPECTIVE RANDOMISED CONTROLLED TRIAL

Author(s):  
Dr Beena. B ◽  
Dr Shyla. S ◽  
Dr P.K. Syamala Devi

Background: Comparative study beween misoprostol and dinoprostone for induction of labour at term has been done at various centres which showed misoprostol to be more effective. This study was done, 18 years back in 2001, when the most common method of induction was dinoprostone. Since then both the drugs has been used equally for induction of labour at term. But in recent past, PGE1 is not being used widely because of fear of untoward effect.  Hence, the importance this article which shows misoprostol to  be more effective with less side effects, easy for storage and low cost. This study is to compare the effectiveness between the two molecules of prostaglandins PGE1 and PGE2 for induction of labour in term. The complication can be reduced by proper selection, 1 to 1 and continuous fetal monitoring. Methods: It was a prospective RCT. 200 Women at term in whom induction of labour was indicated with no contraindications for the use of prostaglandin attending labor room in a tertiary care centre (SAT Hospital Government Medical College Trivandrum) for a period of five months, from September 1St 2000 to January 31st 2001 was chosen to compare the effectiveness of Misoprostol and Dinoprostone for induction of labour at term. Both the groups were comparable in age, parity and bishop score. Results: Among 200, 123(61%) were primigravida and 146 (73%) were in the age group of 21 – 30 yrs. Median induction delivery interval was about 9 hrs shorter in PGE1 group. Only14.14% required oxytocin augmentation in PGE1 Group compared to 50.54% in PGE2 group. There was 8 failures in PGE2 and there was one case of hyper stimulation in PGEI group for which LSCS was done. PGE2 costs 10 times more than PGE1. Conclusion: Misoprostol is faster acting with low induction delivery interval and requirement for oxytoccin augmentation. Misoprostol is low cost drug, affordable to most of our patient from low socio economic status. Keywords: Term pregnancy, Tab Misoprostol, PGE1, Dinoprostone gel, PGE2, Induction of labour.

Author(s):  
V. Saravana Selvan ◽  
Muthamil Silambu ◽  
D. Vinodh Kumaran

<p class="abstract"><strong>Background:</strong> The objective of the study was to compare the advantages and results between coblation adenoidectomy and conventional adenoidectomy by curettage.</p><p class="abstract"><strong>Methods:</strong> The study was<strong> </strong>conducted in Stanley medical college, Chennai (a tertiary care centre) from June 2013 to June 2016. Fifty patients were studied who underwent adenoidectomy. Twenty five patients underwent conventional adenoidectomy by curettage and rest by nasal endoscopy assisted coblation adenoidectomy. Following outcomes were evaluated: pain score on first day, days reporting pain, analgesic days, school absenteeism, endoscopic adenoid grading and intraoperative bleeding.  </p><p class="abstract"><strong>Results:</strong> Patients who underwent coblation adenoidectomy showed better results during follow up with lesser complications.</p><p class="abstract"><strong>Conclusions:</strong> Coblation adenoidectomy is a better technique when compared to conventional technique of curettage.</p>


2016 ◽  
Vol 3 (1) ◽  
pp. 52-55
Author(s):  
RN Mandal ◽  
Z Ahmed ◽  
A Mishra ◽  
RC Das

Background and Objectives: Envenomation by poisonous snakes is considered as an occupational hazard. Snake bite is a common medical emergency and one of the important causes of mortality and morbidity in tropical region.Material and Methods: The present study was conducted in the emergency department of JMCTH. All the patients admitted to JMCTH from April 2014 to November 2014 with snake bite were followed up from the time of admission to throughout their stay in hospital. The data was obtained from hospital case records, direct interrogation from relatives, friends, person accompanying the patients. The information was collected in a pre-formed Proforma. Data were entered and analyzed using Microsoft Excel.Results: The victims of snake bite predominantly were male. Maximum numbers of snake bite cases were between the age group of 31 to 40 yrs and of low socio-economic status. 67.34 % cases were from rural areas and farmers were the most common victim (69.38 %).Conclusion: Maximum cases occurred during the summer and pre-monsoon months, during daytime and involved the lower limbs. Ptosis was the chief neurotoxic feature followed by dysarthria.Janaki Medical College Journal of Medical Sciences (2015) Vol. 3 (1):52-55


2019 ◽  
Vol 6 (4) ◽  
pp. 1247
Author(s):  
Rahul Singh ◽  
Shashank Shekhar Tripathi ◽  
Ankur Tripathi ◽  
Himansha Pandey

Background: Wound healing depends upon a balance between general factors which include nutritional status of the patient and local factors. Assessment of wound healing in relation to nutritional status of the patients in common surgical conditions.Methods: 46 surgical patients admitted in S.R.N. Hospital, Motilal Nehru Medical College, Allahabad during the period from July 2017 to July 2018, were included. Clinical, anthropometric examination, assessment of wound healing and factors affecting wound healing was done.Results: The mean age of the males patients were 38 years and that of female 33 years. Out of 46 patients included in our study 71.74% were male and 28.26% were females, and among these 15.15% of male and 38.46% female were malnourished. Percentage of wound contraction was 11.38% among the healthy and 2.30% in malnourished group, while the percentage of infection was 14% and 13% among healthy males and female and 20% each for malnourished males and females. Loss of weight was 9.4% and 10.1% among healthy male and female and 6.54% and 7.5% for malnourished male and females. The percentage of wound disruption in our study was 9% among malnourished group.Conclusions: Wound infection and disruption collectively increased the mortality and morbidity significantly in patients of malnourished group. Socio economic status has indirect correlation with wound healing. Malnourishment has a definite effect on wound healing.


2014 ◽  
Vol 62 (2) ◽  

In addition to the delivery of primary care services, recent changes to the NHS in the United Kingdom have placed increasing responsibility on GPs for the commissioning of the full range of health services from prevention through to clinical interventions and rehabilitation. Whilst historically there has always been an expectation that primary care professionals were ideally placed to provide support for prevention as well as treatment, their active engagement in the promotion of physical activity has remained largely superficial. With notable exceptions where individuals have a personal interest or commitment, the majority of health professionals tend to limit themselves to peremptory non-specific advice at best, or frequently don’t broach the subject at all. There are a number of reasons for this including increasing time pressures, a general lack of knowledge, limited evidence and concerns about litigation in the event of an adverse exercise induced event. However in the 1990s there was a surge of interest in the emerging “Exercise on Prescription” model where patients could be referred to community based exercise instructors for a structured “prescription” of exercise in community leisure centres. Despite the continuing popularity of the model there remain problems particularly in getting the active support of health professionals who generally cite the same barriers as previously identified. In an attempt to overcome some of these problems Wales established a national exercise referral scheme with an associated randomised controlled trial. The scheme evaluated well and had subsequently evolved with new developments including integration with secondary and tertiary care pathways, accredited training for exercise instructors and exit routes into alternative community based exercise opportunities.


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