scholarly journals DISABILITY AND EXECUTIVE FUNCTIONS IN SCHIZOPHENIA: A CROSSSECTIONAL STUDY. (RELATION OF DISABILITY WITH EXECUTIVE FUNCTIONS)

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Anil Kumar Sisodia ◽  
Akhil Menia ◽  
Sudhir Kumar ◽  
Rakesh Kumar
Keyword(s):  
Executive Functions ◽  
Clinical Data ◽  
Independent Living ◽  
Negative Symptoms ◽  
Significant Negative Correlation ◽  
Drug Dosage ◽  
Important Target ◽  
Duration Of Illness ◽  
Negative Score

The aim of the study was to see if there is any association between disability, positive- negative symptoms and executive functions in patients of schizophrenia. Study had a crossectional design with purposive sampling in 50 patients with schizophrenia. Subjects were assessed using   sociodemographic        and clinical data sheet, PANSS, IDEAS (disability) and WCST (executive functions). The result of the study revealed that poor executive functioning is responsible for functional impairment in patients with schizophrenia. A significant association was seen between IDEAS and WCST variables in patients of schizophrenia. A significant association was also seen between PANSS (positive and negative score) with IDEAS and WCST variables (disability and executive functions being more strongly associated with negative symptoms). On correlation analysis of socio-demographic and clinical data with IDEAS and WCST variables, a significant correlation (positive) of age and duration of illness was seen with IDEAS. Age and drug dosage were having significant (positive) correlation with WCST variable and education was found to be having significant (negative) correlation with WCST variables. Executive functions and negative symptoms are crucial for functional outcome and independent living and are important target for intervention in order to reduce disability and improve quality of life in patients suffering from Schizophrenia. Keywords: Schizophrenia, Disability, Positive–negative symptoms, Executive functions.

scholarly journals DISABILITY AND EXECUTIVE FUNCTIONS IN SCHIZOPHENIA: A CROSSSECTIONAL STUDY. (RELATION BETWEEN DISABILITY AND POSITIVE, NEGATIVE SYMPTOMS)

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Anil Kumar Sisodia ◽  
Akhil Menia ◽  
Sudhir Kumar ◽  
Rakesh Kumar
Keyword(s):  
Executive Functions ◽  
Clinical Data ◽  
Independent Living ◽  
Negative Symptoms ◽  
Improve Quality ◽  
Keywords Schizophrenia ◽  
Important Target ◽  
Duration Of Illness ◽  
Negative Score

The aim of the study was to see if there is any association between disability, positive- negative symptoms in patients of schizophrenia. Study had a crossectional design with purposive sampling in 50 patients with schizophrenia. Subjects were assessed using   sociodemographic        and clinical data sheet, PANSS, IDEAS (disability) . The result of the study revealed a significant association was seen between IDEAS and WCST variables in patients of schizophrenia. A significant association was also seen between PANSS (positive and negative score) with IDEAS and WCST variables (disability and executive functions being more strongly associated with negative symptoms). On correlation analysis of socio-demographic and clinical data with IDEAS and WCST variables, a significant correlation (positive) of age and duration of illness was seen with IDEAS. Executive functions and negative symptoms are crucial for functional outcome and independent living and are important target for intervention in order to reduce disability and improve quality of life in patients suffering from Schizophrenia. Keywords: Schizophrenia, Disability, Positive–negative symptoms, Executive functions.

Effect of positive and negative symptoms on schizophrenia related quality of life of hospitalized schizophrenic patients at Sargodha and Lahore: Moderating role of neuropsychiatric symptoms

2020 ◽  
pp. 1-11
Author(s):  
Tehmina kousar ◽  
Muhammad Naveed Riaz
Keyword(s):  
Quality Of Life ◽  
Negative Correlation ◽  
Negative Symptoms ◽  
Significant Positive Correlation ◽  
Neuropsychiatric Symptoms ◽  
Significant Negative Correlation ◽  
Positive Symptoms ◽  
Related Quality ◽  
Schizophrenic Patients

Abstract Objective: The purpose of study was to find out the moderating effect of neuropsychiatric symptoms in the relationship between positive-negative symptoms of schizophrenia with quality of life of schizophrenic patients. Subject and Methods: This cross-sectional study was conducted at Lahore and Sargodha, Pakistan. Data was collected by administering the Positive and Negative of Schizophrenia Questionnaire, Quality of Life of Schizophrenia Scale and Neuropsychiatry Inventory.  SPSS-23 has been used for data analysis. The study has been completed in one year. The data was collected from September 4, 2017 to November 1, 2018 after 10am in the morning. Results: The findings indicate that positive symptoms have significant positive correlation with negative symptoms (p < .001) and neuropsychiatric symptoms (p < .001) whereas significant negative correlation with schizophrenia quality of life (p < .001). Negative symptoms have significant positive correlation with neuropsychiatric symptoms (p < .001) whereas significant negative correlation with schizophrenia related quality of life (p < .001). Neuropsychiatric symptoms have significant negative correlation with schizophrenia quality of life (p < .001) in the study. Moreover, neuropsychiatric symptoms moderated between negative symptoms and schizophrenia related quality of life. Conclusion: In this study, findings suggested that negative symptoms and neuropsychiatric symptoms have positive association with quality of life of schizophrenic patients whereas positive symptoms have inverse relationship. The study also revealed that neuropsychiatric symptoms enhanced the effect of negative symptoms on quality of life of schizophrenic patients. Keywords: Schizophrenia, Positive Symptoms, Negative Symptoms, Quality of Life, Neuropsychiatric Symptoms Continuous...

ASSECSSING MOCA TEST IN SUBACUTE STROKE PATIENTS AND COMPARE MOCA VERSUS MMSE

2016 ◽  
pp. 120-127
Author(s):  
Dinh Toan Nguyen
Keyword(s):  
Human Life ◽  
Statistical Significance ◽  
High Sensitivity ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Female Age ◽  
Subacute Stroke ◽  
Duration Of Illness ◽  
Dsm Iv

Background: Dementia after stroke, particularly subacute period is often overlooked. Today the quality of human life is increasingly high, finding scales that have high value for detection of dementia in patients with stroke is increasingly interested. MoCA test is high sensitivity with mild dementia and identify more abnormalities of awareness caused by vascular, but MoCA have not been studied much in Vietnam. Objective: Assessing MoCA test in subacute stroke patients and compare MoCA versus MMSE in these patients. Subjects: 90 patients with subacute stroke period, these people are being treated at Department of cardiovascular internal medicine at Hue Central Hospital, from 7/2014 - 7/2015. Methods: cross-sectional description and analysis. Results: The mean age is 65.57 ± 13.38, accounting for 54.4% male and 45.6% female. Age, duration of illness has weak correlation with MoCA. The risk factors: hypertension, stroke ischemic transient, alcoholism, smoking, heart disease, diabetes, dyslipidemia related no statistical significance with MoCA. The proportion of dementia in subacute stroke according MoCA is 82.2%. The concordance between MoCA and MMSE was good (kappa = 0.684). Using DSM-IV criteria as the gold standard we found MoCA more valuable in the dementia diagnosis than MMSE (AUC 0.864 versus 0.774, p <0.05). Conclusion: The rate of dementia in stroke subacute period according MoCA is quite high. MoCA is valuable than MMSE in detecting dementia in patients with stroke subacute period, this scale is short, easy to implement so should put into using widely in clinical practice. Key words: MoCA test, subacute stroke, dementia

scholarly journals Community Living, Intellectual Disability and Extensive Support Needs: A Rights-Based Approach to Assessment and Intervention

2021 ◽  
Vol 18 (6) ◽  
pp. 3175
Author(s):  
Laura Esteban ◽  
Patricia Navas ◽  
Miguel Ángel Verdugo ◽  
Víctor B. Arias
Keyword(s):  
Intellectual Disability ◽  
Independent Living ◽  
Structural Equation ◽  
Equation Modeling ◽  
Community Living ◽  
Support Needs ◽  
Related Services ◽  
The Right To Privacy ◽  
The Right

People with intellectual disability (ID) and extensive support needs experience poorer quality of life than their peers whose disability is not as severe. Many of them live in residential settings that limit community participation and prevent them from exercising control over their lives. This work analyzes the extent to which professional practices are aimed at promoting the right to community living for people with ID and extensive support needs, as well as the rights that are particularly linked to it, such as the right to habilitation and rehabilitation and the right to privacy. A specific questionnaire was designed and administered to 729 adults with intellectual disability (M = 37.05; DT = 12.79) living in different settings (family home, residential facilities and group homes). Measurement and structural models were estimated using exploratory structural equation modeling. Results obtained reveal that people with extensive support needs receive less support in terms of guaranteeing their right to independent living and privacy, especially when they live in disability-related services. This study highlights the need to implement and monitor, using valid and reliable indicators, mesosystem strategies that guarantee the right to live and participate in the community, especially for individuals with ID and extensive support needs.

scholarly journals A high degree of knee flexion after TKA promotes the ability to perform high-flexion activities and patient satisfaction in Asian population

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Hyuk-Soo Han ◽  
Jong Seop Kim ◽  
Bora Lee ◽  
Sungho Won ◽  
Myung Chul Lee
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Clinical Data ◽  
Knee Flexion ◽  
Male Gender ◽  
Flexion Angle ◽  
Knee Flexion Angle ◽  
High Flexion ◽  
Standing Up

Abstract Background This study investigated whether achieving a higher degree of knee flexion after TKA promoted the ability to perform high-flexion activities, as well as patient satisfaction and quality of life. Methods Clinical data on 912 consecutive primary TKA cases involving a single high-flexion posterior stabilized fixed-bearing prosthesis were retrospectively analyzed. Demographic and clinical data were collected, including knee flexion angle, the ability to perform high-flexion activities, and patient satisfaction and quality of life. Results Of the cases, 619 (68%) achieved > 130° of knee flexion after TKA (high flexion group). Knee flexion angle and clinical scores showed significant annual changes, with the maximum improvement seen at 5 years and slight deterioration observed at 10 years postoperatively. In the high flexion group, more than 50% of the patients could not kneel or squat, and 35% could not stand up from on the floor. Multivariate analysis revealed that > 130° of knee flexion, the ability to perform high-flexion activities (sitting cross-legged and standing up from the floor), male gender, and bilateral TKA were significantly associated with patient satisfaction after TKA, while the ability to perform high-flexion activities (sitting cross-legged and standing up from the floor), male gender, and bilateral TKA were significantly associated with patient quality of life after TKA. Conclusions High knee flexion angle (> 130°) after TKA increased the ease of high-flexion activities and patient satisfaction. The ease of high-flexion activities also increased quality of life after TKA in our Asian patients, who frequently engage in these activities in daily life.

scholarly journals Adjunctive Garcinia mangostana Linn. (Mangosteen) Pericarp for Schizophrenia: A 24-Week Double-blind, Randomized, Placebo Controlled Efficacy Trial: Péricarpe d’appoint Garcinia mangostana Linn (mangoustan) pour la schizophrénie : un essai d’efficacité de 24 semaines, à double insu, randomisé et contrôlé par placebo

2020 ◽  
pp. 070674372098243
Author(s):  
Alyna Turner ◽  
Andrea Baker ◽  
Olivia M. Dean ◽  
Adam J. Walker ◽  
Seetal Dodd ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Schizoaffective Disorder ◽  
Negative Symptoms ◽  
Controlled Trial ◽  
Safety Data ◽  
Rate Of Change ◽  
Adjunctive Treatment ◽  
Garcinia Mangostana ◽  
Double Blind

Objectives: Garcinia mangostana Linn. (“mangosteen”) pericarp contains bioactive compounds that may target biological pathways implicated in schizophrenia. We conducted a double-blind randomized placebo-controlled trial evaluating the efficacy of adjunctive mangosteen pericarp, compared to placebo, in the treatment of schizophrenia. Methods: People diagnosed with schizophrenia or schizoaffective disorder ( Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition), recruited across 2 sites (Brisbane and Victoria, Australia), were randomized to receive 24 weeks of adjunctive mangosteen pericarp (1,000 mg/day) or matched placebo. The primary outcome measure was the Positive and Negative Symptom Scale total score. Secondary outcomes included positive and negative symptoms, general psychopathology, clinical global severity and improvement, participant reported overall improvement, depressive symptoms, functioning, quality of life, and safety data at 24 and 28 weeks (4 weeks postdiscontinuation). Data were collected from July 2016 to February 2019. Results: Baseline assessments were conducted on 148 people (mangosteen = 74, placebo = 74); data analyses were conducted on 136 (92%) participants with postbaseline data. The treatment group had significantly higher symptom severity compared to placebo, and both groups significantly improved on all symptom, functioning, and quality of life measures over time. No between-group differences were found for the rate of change between baseline and 24 or 28 weeks. Conclusion: Despite promising preclinical and clinical work, our results do not support mangosteen pericarp extract as an adjunctive treatment for schizophrenia or schizoaffective disorder.

scholarly journals Identification of Research Trends in Aging in Place Using Text Mining Analysis

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 50-50
Author(s):  
Ha Neul Kim ◽  
Seok In Nam
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Text Mining ◽  
Independent Living ◽  
Daily Life ◽  
Aging In Place ◽  
Research Trends ◽  
Life Activity ◽  
Daily Life Activity

Abstract Since 1980s professionals and social service providers have focused on aging at the place where people lived. This is the initial concept of the Aging in Place (AIP). Over 40 years, the topics have developed and extended to other disciplines welcoming different perspectives in the study of AIP. Therefore, this study aims to understand the overall research trends in Aging in Place (AIP) studies using text mining analysis to track the evolvement of AIP subtopics not only in Gerontology but also in various fields. To identify the topic trends, we collected the titles, abstracts, and keywords from 1,372 international articles that were published from 1981 to 2019. Then, keywords were extracted and cleaned based on precedent literature and discussions. We analyzed the keywords based on the degree of centrality and visualized the keyword-networks using VOSviewer and Pajek. Top-most popular keywords are “independent living”, “housing”, “older adults”, “home care”, “daily life activity” and “quality of life.” The change in topic trends shows that in the 1980s to early-2000s, research focused on organization and management level of intervention, home(housing) for the older adults, long term care. In the mid-2010s, health-related topics such as daily life activity, health service, health care delivery and quality of life have emerged. Recently, the topics have extended further to technology, caregiver, well-being, and environment design, environmental planning that support independent living of oneself. The research result shows that the interdisciplinary approach regarding AIP is not only inevitable but also encouraged for an in-depth discussion of the field.

scholarly journals Monitoring Health Parameters of Elders to Support Independent Living and Improve Their Quality of Life

Sensors ◽  
2021 ◽  
Vol 21 (2) ◽  
pp. 517
Author(s):  
Ilia Adami ◽  
Michalis Foukarakis ◽  
Stavroula Ntoa ◽  
Nikolaos Partarakis ◽  
Nikolaos Stefanakis ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Independent Living ◽  
Elderly Population ◽  
Well Being ◽  
The Elderly ◽  
Chronic Illnesses ◽  
Age Related ◽  
Self Sufficiency ◽  
Health And Well Being

Improving the well-being and quality of life of the elderly population is closely related to assisting them to effectively manage age-related conditions such as chronic illnesses and anxiety, and to maintain their independence and self-sufficiency as much as possible. This paper presents the design, architecture and implementation structure of an adaptive system for monitoring the health and well-being of the elderly. The system was designed following best practices of the Human-Centred Design approach involving representative end-users from the early stages.

scholarly journals Toxoplasma gondii Infection and Clinical Characteristics of Patients With Schizophrenia: A Systematic Review and Meta-analysis

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Arjen L Sutterland ◽  
David A Mounir ◽  
Juul J Ribbens ◽  
Bouke Kuiper ◽  
Tom van Gool ◽  
...  
Keyword(s):  
Systematic Review ◽  
Toxoplasma Gondii ◽  
Publication Bias ◽  
Clinical Characteristics ◽  
Negative Symptoms ◽  
Age Of Onset ◽  
Meta Analysis ◽  
Random Effects Models ◽  
Duration Of Illness ◽  
Toxoplasma Gondii Infection

Abstract Schizophrenia is associated with an increased prevalence of IgG antibodies against Toxoplasma gondii (T. gondii seropositivity), whereby the infection seems to precede the disorder. However, it remains unclear whether a T. gondii infection affects clinical characteristics of schizophrenia. Therefore, a systematic review and meta-analysis was conducted following PRISMA guidelines examining the association between T. gondii seropositivity and severity of total, positive, or negative symptoms or age of onset in schizophrenia. PubMed, Embase, and PsycInfo were systematically searched up to June 23, 2019 (PROSPERO #CRD42018087766). Random-effects models were used for analysis. Furthermore, the influence of potential moderators was analyzed. Indications for publication bias were examined. From a total of 934 reports, 13 studies were included. No overall effect on severity of total, positive, or negative symptoms was found. However, in patients with a shorter duration of illness T. gondii seropositivity was associated with more severe positive symptoms (standardized mean difference [SMD] = 0.32; P &lt; .001). Similar but smaller effects were seen for total symptoms, while it was absent for negative symptoms. Additionally, a significantly higher age of onset was found in those with T. gondii seropositivity (1.8 y, P = .015), although this last finding was probably influenced by publication bias and study quality. Taken together, these findings indicate that T. gondii infection has a modest effect on the severity of positive and total symptoms in schizophrenia among those in the early stages of the disorder. This supports the hypothesis that T. gondii infection is causally related to schizophrenia, although more research remains necessary.

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