scholarly journals A COMPARATIVE STUDY OF KETOFOL (KETAMINE AND PROPOFOL) WITH PROPOFOL ALONE FOR RECOVERY IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Priyanka Thakur ◽  
Prteet Negi ◽  
Ajay Sood ◽  
Aparna Sharma
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Controlled Trial ◽  
Verbal Command ◽  
Medical College ◽  
Recovery Profile ◽  
Eye Opening ◽  
One Year ◽  
Gandhi Medical College ◽  
Double Blinded ◽  
Mean Time

Background: To compare the recovery in ketofol (ketamine and   propofol) with propofol alone for vas in   patients undergoing laparoscopic cholecystectomy Methods: Prospective, randomized, double blinded controlled trial. After approval by the research ethics committee and written informed valid consent of the patients, the proposed study was carried out for a period of one year in 60  patients , in ASA-I and ASA-II patients, aged between 19 to 60 years of either sex, who were  posted for laproscopic cholecystectomy surgery at Indira Gandhi Medical College, Shimla. Results: Recovery profile was statistically significant for two groups. In group P after stopping infusion ,mean time for eye opening was 8.27 ± 1.28 which was less than group K ( 12.53 ± 1.48).  Mean time of response to verbal command in group P(8.4 ± 1.19) was less than group K (12.5 ± 1.46) and mean time of extubation in group P (9.5 ± 1.25) was also less than group K (14.33 ± 1.52). Conclusion- Patients of Group P after stopping of infusion took less time for eye opening, obeying verbal command and also less time for extubation  in comparison to group K . Keywords: Recovery, Propofol, Ketamine

scholarly journals A COMPARATIVE STUDY OF KETOFOL (KETAMINE AND PROPOFOL) WITH PROPOFOL ALONE TO SEE EFFECT ON PULSE RATE DURING INDUCTION AND MAINTENANCE PHASE OF ANAESTHESIA IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Priyanka Thakur ◽  
Prteet Negi ◽  
. Ajay Sood ◽  
Aparna Sharma
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Pulse Rate ◽  
Postoperative Period ◽  
Controlled Trial ◽  
Maintenance Phase ◽  
Medical College ◽  
Intraoperative Period ◽  
One Year ◽  
Gandhi Medical College ◽  
Double Blinded

Background: In this study, we aimed to evaluate the intra and post-operative pulse rate of ketamine-propofol mixture (Ketofol) infusion in comparison with propofol infusion. Methods: Prospective, randomized, double blinded controlled trial. After approval by the research ethics committee and written informed valid consent of the patients, the proposed study was carried out for a period of one year in 60 patients, in ASA-I and ASA-II patients, aged between 19 to 60 years of either sex, who were  posted for laparoscopic cholecystectomy surgery at Indira Gandhi Medical College, Shimla. Results: HR for group K was significantly increased during intubation(89.30 ± 13.22) , 1 minute after intubation(91.30 ± 14.28), at 5minute (88.73 ± 11.94) and 10  minute(89.17 ± 12.53) in intraoperative period, every 5 minute before extubation(89.77 ± 12.82,89.93 ± 12.50, 90.13 ± 12.42),during extubation(92.10 ± 10.88) and at first 30 minutes in post operative period(88.17 ± 8.76) as compared to baseline HR(82.80 ± 10.95).HR in group P was significantly increased at 1 min after intubation(81.93 ± 10.77) , during extubation (85.80 ± 11.24) and initial 30 minute of postoperative period (82.80 ± 10.56) as compared to baseline HR(76.80 ± 12.55). Conclusion: HR parameter was significantly on higher side in group K during intubation, one -five -10 minutes after intubation , at 15 minutes before extubation , during extubation  and at first 30 minutes of postoperative period  as compared to group P where it significantly increased at one minute after intubation , during extubation and at initial 30 minutes of postoperative period when compared with their respective baselines Keywords: Pulse rate, Propofol, Ketamine

scholarly journals Recovery Profile and Patient Satisfaction After Ambulatory Anesthesia for Dental Treatment—A Crossover Comparison Between Propofol and Sevoflurane

2016 ◽  
Vol 63 (4) ◽  
pp. 175-180 ◽  
Author(s):  
Keita Ohkushi ◽  
Ken-ichi Fukuda ◽  
Yoshihiko Koukita ◽  
Yuzuru Kaneko ◽  
Tatsuya Ichinohe
Keyword(s):  
Patient Satisfaction ◽  
Dental Treatment ◽  
Recovery Phase ◽  
Day Case ◽  
Ambulatory Anesthesia ◽  
Verbal Command ◽  
Recovery Profile ◽  
Eye Opening ◽  
Emergence Phase ◽  
Severe Anxiety

The purpose of this study was to determine which anesthetic was preferable for ambulatory anesthesia: propofol alone or sevoflurane alone. A crossover study was performed to compare the recovery profile and patient satisfaction after 2 anesthesia methods. Twenty healthy patients with severe anxiety toward dental treatment undergoing 2 sessions of day-case dental treatment received either propofol or sevoflurane anesthesia. The order of these methods was randomized. The depths of anesthesia were kept constant using bispectral index (BIS) monitoring. Observations on recovery profiles were performed in the emergence phase, in the recovery phase, and 24 hours after discharge. Patient satisfaction and preference were obtained by a questionnaire. Most of the recovery profiles in the emergence phase such as time to eye opening to respond to verbal command, time to BIS ≥ 75, and time to extubation were shorter in the sevoflurane group than in the propofol group. All recovery profiles in the recovery phase showed no differences between the 2 groups. Based on the subject's satisfaction and preference, propofol was evaluated as a better anesthetic for ambulatory anesthesia than sevoflurane. Higher patient satisfaction and a greater preference for future dental treatment were revealed for propofol anesthesia. Propofol may be more suitable for ambulatory anesthesia for dental treatment.

scholarly journals Is suture ligation of cystic duct in laparoscopic cholecystectomy a safe alternative to clipping? Our experience in a rural centre

2019 ◽  
Vol 6 (10) ◽  
pp. 3715
Author(s):  
K. R. Manoj Prabu ◽  
Dhinesh Balaji ◽  
Vishwanath M. Pai
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Complications ◽  
Cystic Duct ◽  
Operating Time ◽  
Cost Effective ◽  
Safe Alternative ◽  
Suture Ligation ◽  
Medical College ◽  
The Mean ◽  
Mean Time

Background: Laparoscopic cholecystectomy is one of the most common surgeries performed nowadays. It remains an enigma regarding efficacy, safety and postoperative complications for using suture ligation for ligating cystic duct in laparoscopic cholecystectomy. The aim of the present study was to study the efficacy of ligating the cystic duct with sutures in laparoscopic cholecystectomy.Methods: This prospective study was performed between June 2018 and April 2019 in Saveetha Medical College and Hospital, in a rural center, Kanchipuram, India. All the patients included consented for the study. Patients who underwent subtotal cholecystectomy were excluded from the study.Results: The study included 70 patients who underwent laparoscopic cholecystectomy in a single unit. All cases were operated by a single surgeon. Of the 70 patients, the Cystic duct (CD) was simply ligated in 55 patients with CD <5 mm in diameter. The CD in 15 of those patients had to be divided and sutured in continuity for wide CD (>5 mm). The mean time for ligation of cystic duct was 5 min. Similarly, the mean time for ligation of cystic artery was 1.50 min. The mean operative time was 50 mins. There were no postoperative complications, such as bile leakage.Conclusions: SL of the CD is a very safe and secure alternative to the application of metal clips. It can be used in dilated CD, readily available and very cost effective and the complications of clips are avoided. The only disadvantage is that it needs expertise to perform and subsequently increasing the operating time. This technique is recommended in all laparoscopic cholecystectomies, especially in difficult cases.

scholarly journals Role of preoperative nutrition in gastro-intestinal cancer patients: a prospective study

2016 ◽  
Vol 4 (1) ◽  
pp. 131
Author(s):  
Samir Shukla ◽  
M. C. Songra ◽  
Naveen Kumar Patbamniya ◽  
M. Damor ◽  
Vijay Tyagi
Keyword(s):  
Prospective Study ◽  
Clinical Signs ◽  
Normal Diet ◽  
Control Group ◽  
Medical College ◽  
Preoperative Nutrition ◽  
Total Parentral Nutrition ◽  
One Year ◽  
Gandhi Medical College ◽  
A Prospective Study

Background:This prospective study was carried out to compare outcome and postoperative complication in patients with gastro-intestinal malignancy who received preoperative total parentral nutrition with those whom doesn’t.Methods: The study was a prospective single-centre, two-arm, conducted in department of general surgery, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India of one year duration, a total of 60 patients with G. I. malignancy, with or without sign of malnutrition, were included in the study. Patients were randomized and 30 patients were placed in each arm (interventional and control group) patients in the control group were asked to continue their normal feeding while interventional arm were given TPN in addition to their normal diet, for 7 to 10 days before surgery.Results:Infectious complications were more in control group, while one case each of pneumonia and sepsis was observed in patients receiving supplementation. Complications related to nutritional status of the patient like wound infection and anastomotic leak were observed only in patients without supplementation. There was no death observed in interventional group but two deaths occurred in control group.Conclusions:Preoperative nutritional support is beneficial and should be routinely used in abdominal and gastrointestinal cancer patient with or without clinical signs of malnutrition.

Preoperative Oral Rofecoxib and Postoperative Pain in Patients after Laparoscopic Cholecystectomy: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial

2005 ◽  
Vol 71 (10) ◽  
pp. 827-829 ◽  
Author(s):  
Rob Schuster ◽  
David Stewart ◽  
Lynn Schuster ◽  
Gregory Greaney ◽  
Kenneth Waxman
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Placebo Group ◽  
Postoperative Pain ◽  
Hospital Stay ◽  
Controlled Trial ◽  
Group Versus ◽  
Cox 2 ◽  
Double Blinded ◽  
Cox 2 Inhibitors ◽  
The Impact

Cyclooxygenase-2 (COX-2) inhibitors are a class of drugs that may avoid some of the side effects of narcotics and nonsteroidal anti-inflammatory drugs (NSAIDs). We performed a randomized, double-blinded, placebo-controlled trial giving a single oral dose of the COX-2 inhibitor rofecoxib 25 mg or placebo preoperatively to determine the impact upon postoperative pain, complications, narcotic use, and hospital stay after laparoscopic cholecystectomy. Investigators and patients were blinded. Pain was measured on a 10-point visual analogue scale. Eighty patients were randomized: 40 to the rofecoxib group and 40 to the placebo group. The amount of pain between the two groups postoperatively was equivalent. Pain was recorded at 1 hour, 4.03 ± 1.93 in the rofecoxib group versus 4.38 ± 1.34 in the placebo group ( P = 0.36); at 6 hours, 3.00 ± 1.12 in the rofecoxib group versus 2.78 ± 0.78 in the placebo group ( P = 0.42); and at 24 hours, 1.64 ± 0.67 in the rofecoxib group versus 2.68 ± 1.90 in the placebo group ( P = 0.17). The amount of pain medication received and lengths of hospital stay was not significantly different between the two groups. Our data demonstrate no significant benefit of preoperative oral rofecoxib in patients undergoing laparoscopic cholecystectomy.

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