scholarly journals XANTHO-GRANULOMATOUS OSTEOMYELITIS OF STERNUM, RESEMBLING A TUMOR: FIRST REPORTED CASE

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Abhay Manchanda ◽  
Aanchal Manchanda ◽  
Yash Sharma ◽  
Ashish Jain
Keyword(s):  
Granulomatous Inflammation ◽  
Image Intensifier ◽  
Open Biopsy ◽  
Rare Type ◽  
Methyl Prednisolone ◽  
First Case ◽  
Short Course ◽  
Manubrium Sterni ◽  
Keloid Formation ◽  
Chest Radiology

Xantho-granulomatous inflammation is a rare type of chronic inflammation, when seen in the bones it is known as xanthogranulomatous osteomyelitis (XO). Here we present a rare case XO of the manubrium sterni, to best of our knowledge this is the first diagnosed. XO of the manubrium sterni mimics radiologically as tuberculosis and as eosinophillic granuloma. We have a 23 year old lady who presented with pain and swelling in the anterior chest, radiology was done and finally the lesion was biopsied. We accepted the patient as Xanthomatous Osteomyelitis and planned for into excision of manubrium sterni, with a flap comprising of ribs and muscle advancements to cover the midline gap in the chest wall, that would have been created. Meanwhile she was put on a short course of antibiotics. It had been observed that the first open biopsy scar had exhibited a tendency for keloid formation. Hence, the risk of final surgery incision producing a disfiguring keloid was informed to the patient, which unfortunately led the patient deter surgery indefinitely, since she was to be married soon. We proposed a local injection of steroid into the lesion to minimize the inflammation. Under image intensifier we injected 40 mg of methyl prednisolone into the tumor. There was some tolerable discomfort the next day of injection that eventually subsided in 3 days. However, the biopsy came inconclusive second core needle biopsy came as XO. Since 1984 with the first case by Cozzutto et al, only 17 cases have been reported in the worldwide literature including us.

scholarly journals 'Atypical Localized Not Well-Specified Cases' a case study of a rare type of Localized Lichen Myxedematosus

2018 ◽  
Vol 30 (1) ◽  
pp. 44-46
Author(s):  
Mohammad A Hye ◽  
Mohammad A Quyum ◽  
Roushan A Begum
Keyword(s):  
Excellent Result ◽  
Oral Prednisolone ◽  
Skin Involvement ◽  
Rare Type ◽  
Systemic Involvement ◽  
First Case ◽  
Short Course ◽  
Distinct Disease ◽  
Recent Classification ◽  
Lichen Myxedematosus

Lichen Myxedematosus (LM) is an uncommon and distinct disease entity characterized by cutaneous mucin deposition in dermis. It is classified in several subtypes depending on many factors including the monoclonal gammapathy, pattern of skin involvement and systemic involvement. We now present a case of LM which is localized in respect of skin involvement but according to recent classification it falls into a diagnosis of 'atypical localized not well- specified cases'. This is a very rare case and to the best of our knowledge, it is the first case report in medical literature until now. We treated the case with a short course of oral Prednisolone and got excellent result. Patient has been followed up in every 6 month for last 13 yrs and observed no progression to scleromyxedema.Medicine Today 2018 Vol.30(1): 44-46

scholarly journals Chordoid meningioma: report of two cases

2003 ◽  
Vol 61 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Oswaldo Ignácio de Tella Jr ◽  
Marco Antonio Herculano ◽  
Mirto Nelso Prandini ◽  
João Norberto Stavile ◽  
Antonio de Pádua Furquim Bonatelli
Keyword(s):  
Ct Scan ◽  
Male Patient ◽  
Infratemporal Fossa ◽  
Growth Patterns ◽  
Partial Removal ◽  
Rare Type ◽  
Chordoid Meningioma ◽  
First Case ◽  
Pathologic Findings ◽  
Histopathologic Findings

We present CT scan, MRI and histopathologic findings of two patients harboring a rare type of meningioma. In the first case, a 52 year-old male patient, a large parasellar mass invading the cavernous sinus, infiltrating the infratemporal fossa and extending as low as C2 was founded. The tumor was isointense on T1, enhanced strongly with gadolinium injection, and was hyperintense on T2. In the second case, a 19-year-old male patient, a large high density temporal right mass was disclosed by CT scan. Both patients were taken to surgery. In the first case, only a partial removal was possible to be accomplished due to a severe intra operative bleeding. In the second case, the tumor was totally removed. Both showed characteristic pathologic findings of a meningioma resembling a chordoma. Meningioma is a relatively common intracranial tumor, occurring most frequently in adults, showing a wide variety of growth patterns. We described a pattern that had a peculiar chordoma-like appearance. The pathological findings and the differential diagnosis from chordoma are discussed.

scholarly journals External supravesical hernia is a rare type of abdominal wall hernia: A case report

2017 ◽  
Vol 7 (1) ◽  
pp. 40-41 ◽  
Author(s):  
Pankaj Kumar Saha ◽  
Ratna Rani Roy ◽  
Mohammad Emrul Hasan Khan ◽  
Md Mamunur Rahman ◽  
Kazi Shafiqul Alam ◽  
...  
Keyword(s):  
Case Report ◽  
Inguinal Hernia ◽  
Abdominal Wall ◽  
Abdominal Wall Hernia ◽  
Surgical Anatomy ◽  
Rare Type ◽  
First Case ◽  
Made In

The first case of external supravesical hernia was made in 1804; but it is so rare that it is very difficult to find any case reported in Bangladesh. Here a case of external supravesical hernia is described in a male who was presented with a left sided direct incomplete reducible inguinal hernia. This report aims to review and discuss the surgical anatomy of these rare supravesical hernias and calls attention to the confusing presentation and treatment of this conditionJ Shaheed Suhrawardy Med Coll, 2015; 7(1):40-41

scholarly journals Patient re-presents to the clinic with reactive arthritis in the right hip after covid-19 infection: A case report

2021 ◽  
Author(s):  
Kamyar Shokraee ◽  
Soroush Moradi ◽  
Tahereh Eftekhari ◽  
Rasoul Shajari ◽  
Maryam Masoumi
Keyword(s):  
Case Report ◽  
Reactive Arthritis ◽  
Respiratory Symptoms ◽  
Gastrointestinal Infection ◽  
Case Presentation ◽  
Sexually Transmitted ◽  
Methyl Prednisolone ◽  
First Case ◽  
The Right

Abstract Background: SARS-COV-2, first reported in December 2019, usually presents with respiratory symptoms but can have various other manifestations and sequelae. One of the rare complications of COVID-19 infection is Reactive Arthritis. This complication is more likely to occur following sexually transmitted or gastrointestinal infection.Case presentation: Herein, we report a 58 years old woman hospitalized following COVID-19 infection and was discharged after a week. She consequently presented to the clinic ten days after her discharge, complaining of walking difficulties and radiating pain in her right hip. After ultrasound and MRI, she was diagnosed with reactive arthritis inflammation in the hip’s neck. Other known microorganisms responsible for reactive arthritis were ruled out before attributing it to the earlier COVID-19 infection. She reached remission after being treated using a combination of indomethacin and depot methyl-prednisolone for 14 days. Conclusion: To our knowledge, this is the first case of reactive arthritis caused by SARS-COV-2 in the hip. Further attention should be paid to symptoms occurring after an episode of infection with COVID-19 in order to expand our understanding of the disease and the symptoms with which it can manifest.

scholarly journals Borderline tuberculoid leprosy, lupus vulgaris and pulmonary tuberculosis: A rare association

2019 ◽  
Vol 9 (1) ◽  
pp. 1505-1507
Author(s):  
Palzum Sherpa ◽  
Amit Amatya ◽  
Trishna Kakshapati
Keyword(s):  
Pulmonary Tuberculosis ◽  
Extrapulmonary Tuberculosis ◽  
Granulomatous Inflammation ◽  
Simultaneous Occurrence ◽  
Lupus Vulgaris ◽  
Posterior Aspect ◽  
Mycobacterial Infections ◽  
Cutaneous Tuberculosis ◽  
First Case ◽  
Tuberculoid Leprosy

Tuberculosis and leprosy are chronic mycobacterial infections that elicit granulomatous inflammation. The incidence of co-existence of pulmonary tuberculosis and leprosy has ranged from 2.5%-13.4%.1 Cutaneous tuberculosis is a variant of extrapulmonary tuberculosis and its  simultaneous occurrence with leprosy is uncommon. The concomitant presence of leprosy, pulmonary as well as cutaneous tuberculosis is rare. We report a case of borderline tuberculoid leprosy, lupus vulgaris and pulmonary tuberculosis in a 45 years male who presented to the dermatology outpatient department with three morphologically distinct skin lesions over the posterior aspect of right leg. Ours is presumably the first case reported from Nepal, a country where both of these mycobacterial infections are endemic.

scholarly journals Double Filtration Plasmapheresis Treatment of Refractory Multiple Sclerosis Relapsed on Fingolimod: A Case Report

2020 ◽  
Vol 10 (21) ◽  
pp. 7404
Author(s):  
Roberto De Masi ◽  
Stefania Orlando ◽  
Salvatore Accoto
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Improvement ◽  
Gamma Globulin ◽  
Neurological Diseases ◽  
Methyl Prednisolone ◽  
Double Filtration Plasmapheresis ◽  
First Case ◽  
Double Filtration ◽  
Steroid Refractory ◽  
Inflammatory Effect

Double filtration plasmapheresis (DFPP) is an emerging semi-selective apheretic method for treating immuno-mediated neurological diseases. Here we report the first case of steroid-refractory relapsed multiple sclerosis (MS) on Fingolimod (FTY), treated effectively by this technique, in a 37-year-old woman. This condition is thought to be caused by soluble inflammatory species, but its demyelinating pattern is unknown; moreover, despite megadoses of intravenous 6-methyl prednisolone, it induces severe neurological deterioration, but dramatically responded to DFPP in our patient. The clinical improvement was driven by a strong DFPP-induced anti-inflammatory effect, with significant reduction of C3/C4 components, total gamma globulin concentrations (IgG), and gamma-fibrinogen (FGG), resulting in a brain pseudoatrophy phenomenon. Our findings are: first, the steroid-refractory relapsed MS on FTY, however serious, can be treated with DFPP; second, given the good clinical improvement due to the DFPP-induced neuroinflammatory components removal, this clinical condition can be associated with a Lucchinetti pattern II of demyelination.

scholarly journals Genitourinary tuberculosis in North America: A rare clinical entity

2015 ◽  
Vol 9 (7-8) ◽  
pp. 484 ◽  
Author(s):  
Michael W Sourial ◽  
Fadi Brimo ◽  
Ruth Horn ◽  
Sero Andonian
Keyword(s):  
North America ◽  
Percutaneous Nephrolithotomy ◽  
Left Kidney ◽  
Granulomatous Inflammation ◽  
Renal Stones ◽  
High Index ◽  
Canadian Woman ◽  
Radiologic Findings ◽  
First Case ◽  
High Index Of Suspicion

Introduction: Although tuberculosis (TB) is the most common cause of mortality from infectious diseases worldwide, genitourinary TB in North America is rare. We review 3 cases of genitourinary TB diagnosed within the last 5 years.Cases: The first case is that of a 76-year-old African-Canadian woman who was referred for percutaneous nephrolithotomy of right lower pole renal stones. Although renal TB was suspected, her initial urinary TB culture was negative. On follow-up imaging, she developed bilateral ureteral thickening and ureteroscopic biopsy confirmed necrotizing granulomata. Repeat urine cultures were positive for M. tuberculosis. The second case is a 73-yearold Italian-Canadian woman who was referred for ureteroscopic biopsy of left thickened ureter to rule out urothelial carcinoma. Initial urine TB cultures were negative, despite biopsies confirming granulomatous inflammation. She was closely followed with urine cytologies and TB cultures. Repeat urine culture was positive for M. tuberculosis. Both patients were treated with a course of anti-tuberculous agents and indwelling ureteral stents to relieve ureteral obstruction. The third case is a 70-year-old Cree woman who was referred for percutaneous nephrolithotomy of a left “staghorn stone” in an atrophic left kidney. Thirty years earlier she had been treated for pulmonary TB in addition to ileocystoplasty for a “thimble” bladder. A computed tomography scan showed autonephrectomized left kidney. Her urine TB cultures were negative. She was placed on prophylactic antibiotics for her recurrent bacterial urinary tract infections.Conclusion: Genitourinary TB may present in various subtle ways, and the astute clinician must have a high index of suspicion for this disease in patients with atypical clinical and radiologic findings. In addition, TB urine cultures should be repeated when there is high index of suspicion.

Autoimmune/inflammatory syndrome induced by methylmethacrylate associated to seronegative antiphospholipid syndrome and diffuse large B-cell non-Hodgkin’s lymphoma

Lupus ◽  
2020 ◽  
Vol 29 (10) ◽  
pp. 1292-1296
Author(s):  
Olga Vera-Lastra ◽  
Eduardo Rojas-Milán ◽  
Ana Lilia Peralta-Amaro ◽  
Magdalena Sánchez-Uribe ◽  
Leopoldo Isaac Cruz-González ◽  
...  
Keyword(s):  
B Cell ◽  
Antiphospholipid Syndrome ◽  
Hodgkin’S Lymphoma ◽  
Granulomatous Inflammation ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
First Case ◽  
Non Hodgkin's Lymphoma ◽  
Inflammatory Syndrome ◽  
Large B Cell

Background Autoimmune/inflammatory syndrome induced by adjuvants has been associated with different substances used for cosmetic purposes; for example, silicone, methylmethacrylate, autoimmune disorders and cancer. Discussion A 40-year-old man with a prior history of methylmethacrylate injection in the buttocks for aesthetic purposes 8 years ago, presented with deep venous thrombosis in the left leg 6 months ago, accompanied with inflammation, hardening, changes in colour, ulceration in the buttocks, arthritis, myalgias and fever. Weak and moderate lupus anticoagulant and low levels of anticardiolipin antibodies were present. Thoracoabdominal tomography showed hepatosplenomegaly and a pulmonary nodule, the biopsy of which showed chronic granulomatous inflammation. After a month, a new chest tomography showed multiple nodular pulmonary lesions. The new pulmonary biopsy showed a diffuse large B-cell non-Hodgkin’s lymphoma which was treated with cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab for four cycles, with good response of the autoimmune/inflammatory syndrome, but partial response of the diffuse large B-cell non-Hodgkin’s lymphoma. Conclusion We describe the first case of seronegative antiphospholipid syndrome and lymphoma associated with methylmethacrylate in a patient with autoimmune/inflammatory syndrome.

scholarly journals Struma ovarii: two case reports of a rare teratoma of the ovary

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Obed Rockson ◽  
Christine Kora ◽  
Abdelbassir Ramdani ◽  
Aabdi Basma ◽  
Tariq Bouhout ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Case Reports ◽  
Thyroid Tissue ◽  
Ovarian Teratoma ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Struma Ovarii ◽  
Rare Type ◽  
Benign Condition ◽  
First Case

Abstract Struma ovarii is an extremely rare type of ovarian teratoma distinguished by the unusual presence of thyroid tissue. It is usually a benign condition; however, malignant transformation is sometimes detected. The diagnosis relies on histopathological examination and is infrequently made on routine investigations. We report two cases of struma ovarii: one benign and the other malignant. The first case involved a 27-year-old woman who underwent a right ovarian cystectomy for an incidental ultrasonographic finding of a solid right adnexal mass. The diagnosis of a benign struma was made after histopathological study. The second case involved a 68-year-old woman who underwent a right salpingo-oophorectomy for a right ovarian bulky mass and the histopathological diagnosis was consistent with that of a malignant struma. We examine the challenges involved in the diagnosis and management of this rare entity.

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