scholarly journals 'Atypical Localized Not Well-Specified Cases' a case study of a rare type of Localized Lichen Myxedematosus

2018 ◽  
Vol 30 (1) ◽  
pp. 44-46
Author(s):  
Mohammad A Hye ◽  
Mohammad A Quyum ◽  
Roushan A Begum
Keyword(s):  
Excellent Result ◽  
Oral Prednisolone ◽  
Skin Involvement ◽  
Rare Type ◽  
Systemic Involvement ◽  
First Case ◽  
Short Course ◽  
Distinct Disease ◽  
Recent Classification ◽  
Lichen Myxedematosus

Lichen Myxedematosus (LM) is an uncommon and distinct disease entity characterized by cutaneous mucin deposition in dermis. It is classified in several subtypes depending on many factors including the monoclonal gammapathy, pattern of skin involvement and systemic involvement. We now present a case of LM which is localized in respect of skin involvement but according to recent classification it falls into a diagnosis of 'atypical localized not well- specified cases'. This is a very rare case and to the best of our knowledge, it is the first case report in medical literature until now. We treated the case with a short course of oral Prednisolone and got excellent result. Patient has been followed up in every 6 month for last 13 yrs and observed no progression to scleromyxedema.Medicine Today 2018 Vol.30(1): 44-46

scholarly journals XANTHO-GRANULOMATOUS OSTEOMYELITIS OF STERNUM, RESEMBLING A TUMOR: FIRST REPORTED CASE

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Abhay Manchanda ◽  
Aanchal Manchanda ◽  
Yash Sharma ◽  
Ashish Jain
Keyword(s):  
Granulomatous Inflammation ◽  
Image Intensifier ◽  
Open Biopsy ◽  
Rare Type ◽  
Methyl Prednisolone ◽  
First Case ◽  
Short Course ◽  
Manubrium Sterni ◽  
Keloid Formation ◽  
Chest Radiology

Xantho-granulomatous inflammation is a rare type of chronic inflammation, when seen in the bones it is known as xanthogranulomatous osteomyelitis (XO). Here we present a rare case XO of the manubrium sterni, to best of our knowledge this is the first diagnosed. XO of the manubrium sterni mimics radiologically as tuberculosis and as eosinophillic granuloma. We have a 23 year old lady who presented with pain and swelling in the anterior chest, radiology was done and finally the lesion was biopsied. We accepted the patient as Xanthomatous Osteomyelitis and planned for into excision of manubrium sterni, with a flap comprising of ribs and muscle advancements to cover the midline gap in the chest wall, that would have been created. Meanwhile she was put on a short course of antibiotics. It had been observed that the first open biopsy scar had exhibited a tendency for keloid formation. Hence, the risk of final surgery incision producing a disfiguring keloid was informed to the patient, which unfortunately led the patient deter surgery indefinitely, since she was to be married soon. We proposed a local injection of steroid into the lesion to minimize the inflammation. Under image intensifier we injected 40 mg of methyl prednisolone into the tumor. There was some tolerable discomfort the next day of injection that eventually subsided in 3 days. However, the biopsy came inconclusive second core needle biopsy came as XO. Since 1984 with the first case by Cozzutto et al, only 17 cases have been reported in the worldwide literature including us.

scholarly journals Chordoid meningioma: report of two cases

2003 ◽  
Vol 61 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Oswaldo Ignácio de Tella Jr ◽  
Marco Antonio Herculano ◽  
Mirto Nelso Prandini ◽  
João Norberto Stavile ◽  
Antonio de Pádua Furquim Bonatelli
Keyword(s):  
Ct Scan ◽  
Male Patient ◽  
Infratemporal Fossa ◽  
Growth Patterns ◽  
Partial Removal ◽  
Rare Type ◽  
Chordoid Meningioma ◽  
First Case ◽  
Pathologic Findings ◽  
Histopathologic Findings

We present CT scan, MRI and histopathologic findings of two patients harboring a rare type of meningioma. In the first case, a 52 year-old male patient, a large parasellar mass invading the cavernous sinus, infiltrating the infratemporal fossa and extending as low as C2 was founded. The tumor was isointense on T1, enhanced strongly with gadolinium injection, and was hyperintense on T2. In the second case, a 19-year-old male patient, a large high density temporal right mass was disclosed by CT scan. Both patients were taken to surgery. In the first case, only a partial removal was possible to be accomplished due to a severe intra operative bleeding. In the second case, the tumor was totally removed. Both showed characteristic pathologic findings of a meningioma resembling a chordoma. Meningioma is a relatively common intracranial tumor, occurring most frequently in adults, showing a wide variety of growth patterns. We described a pattern that had a peculiar chordoma-like appearance. The pathological findings and the differential diagnosis from chordoma are discussed.

scholarly journals External supravesical hernia is a rare type of abdominal wall hernia: A case report

2017 ◽  
Vol 7 (1) ◽  
pp. 40-41 ◽  
Author(s):  
Pankaj Kumar Saha ◽  
Ratna Rani Roy ◽  
Mohammad Emrul Hasan Khan ◽  
Md Mamunur Rahman ◽  
Kazi Shafiqul Alam ◽  
...  
Keyword(s):  
Case Report ◽  
Inguinal Hernia ◽  
Abdominal Wall ◽  
Abdominal Wall Hernia ◽  
Surgical Anatomy ◽  
Rare Type ◽  
First Case ◽  
Made In

The first case of external supravesical hernia was made in 1804; but it is so rare that it is very difficult to find any case reported in Bangladesh. Here a case of external supravesical hernia is described in a male who was presented with a left sided direct incomplete reducible inguinal hernia. This report aims to review and discuss the surgical anatomy of these rare supravesical hernias and calls attention to the confusing presentation and treatment of this conditionJ Shaheed Suhrawardy Med Coll, 2015; 7(1):40-41

scholarly journals High dose, short course prednisolone for acute idiopathic thrombocytopenic purpura (ITP) in children

2017 ◽  
Vol 4 (5) ◽  
pp. 1705
Author(s):  
Aparna Jayaraman ◽  
Sarthak Das ◽  
Niranjan Biswal ◽  
Dillikumar C. G. ◽  
Bhavna Ashok Bade
Keyword(s):  
Platelet Count ◽  
Oral Prednisolone ◽  
High Dose ◽  
Study Group ◽  
Short Course ◽  
Significant Difference ◽  
Clinically Significant ◽  
Acute Itp ◽  
Limiting Condition ◽  
Dramatic Presentation

Background: Immune thrombocytopenia (ITP) is a relatively benign and self-limiting condition. Though its dramatic presentation with skin or mucosal bleeds could be worrisome, the incidence of serious bleeding like intracranial hemorrhage (ICH) is relatively low (<1%) occurs at a very low count of <20,000 /mm3. The aim of the study was to compare a high dose, short course prednisolone with conventional Prednisolone therapy in the treatment of acute ITP of childhood.Methods: 20 cases and 18 retrospective controls with acute ITP were enrolled. The study group received 5mg/kg/day of oral prednisolone for four days. All the controls had received 2mg/kg/day of oral prednisolone for 14 days, tapered and stopped over the third week.Results: The study group was found to have significant decrease in clinical bleeding, (p=0.02), and significant increase in platelet count by day 3 of treatment (p=0.03) but no significant difference in platelet counts on day 7 of treatment (p=0.07) when compared with the control group.Conclusions: We conclude that the high dose short course oral prednisolone is significantly better than the conventional regimen in reducing clinically significant bleeding and raising the platelet count to safe levels within first 72 hours of therapy. 

scholarly journals Scleromyxedema (Arndt - Gottron Syndrome) Developing Under Tenofovir Treatment for Hepatitis B: Unique Presentation in a Bulgarian Patient!

2019 ◽  
Vol 7 (5) ◽  
pp. 782-785 ◽  
Author(s):  
Ivanka Temelkova ◽  
James Patterson ◽  
Georgi Tchernev
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatitis Virus ◽  
Histological Study ◽  
Drug Induced ◽  
Systemic Involvement ◽  
First Case ◽  
The Face ◽  
Hepatitis B Treatment

BACKGROUND: Scleromyxedema, also referred to as the Arndt-Gottron (S-AG) syndrome or the systemic form of Lichen myxedematosus (LM), is a cutaneous mucinosis with a chronic course and high lethality from systemic involvement of other organs and systems. Interesting in several aspects is the association between scleromyxedema and viral hepatitis about: 1) hepatitis virus infection as a possible etiological factor for the development of scleromyxedema, 2) antiretroviral therapy for the treatment of hepatitis as a method of reversing scleromyxedema and 3) antiviral drugs as inducers of scleromyxedema. CASE REPORT: We present a 53-year old patient who for nine months had been on tenofovir disoproxil 245 mg (0-0-1) therapy for chronic hepatitis B. Three months after the start of antiviral therapy (i.e. for a period of 6 months), the patient observed swelling, itching and hardening of the skin on the face, ears and hands, which subsequently spread throughout the trunk. Subsequent histological study of a skin biopsy revealed changes of scleromyxedema at an advanced stage, though immunoelectrophoresis of serum and urine excluded the presence of paraproteinaemia or para proteinuria. Systemic antihistamine and topical corticosteroid therapy were instituted. Bone involvement with possible plasmacytoma was excluded, and a myelogram showed evidence of an erythroblastic reaction of bone marrow. CONCLUSION: We believe that drug-induced scleromyxedema is a rare but possible phenomenon. We describe the first case of tenofovir-induced scleromyxedema within the framework of chronic hepatitis B treatment.

Lichen myxedematosus with systemic involvement: Clinical and autopsy findings

2001 ◽  
Vol 45 (4) ◽  
pp. 606-608 ◽  
Author(s):  
Barbara Loggini ◽  
Raffaele Pingitore ◽  
Alessandro Avvenente ◽  
Giuseppina Giuliano ◽  
Paolo Barachini
Keyword(s):  
Systemic Involvement ◽  
Autopsy Findings ◽  
Lichen Myxedematosus

scholarly journals Struma ovarii: two case reports of a rare teratoma of the ovary

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Obed Rockson ◽  
Christine Kora ◽  
Abdelbassir Ramdani ◽  
Aabdi Basma ◽  
Tariq Bouhout ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Case Reports ◽  
Thyroid Tissue ◽  
Ovarian Teratoma ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Struma Ovarii ◽  
Rare Type ◽  
Benign Condition ◽  
First Case

Abstract Struma ovarii is an extremely rare type of ovarian teratoma distinguished by the unusual presence of thyroid tissue. It is usually a benign condition; however, malignant transformation is sometimes detected. The diagnosis relies on histopathological examination and is infrequently made on routine investigations. We report two cases of struma ovarii: one benign and the other malignant. The first case involved a 27-year-old woman who underwent a right ovarian cystectomy for an incidental ultrasonographic finding of a solid right adnexal mass. The diagnosis of a benign struma was made after histopathological study. The second case involved a 68-year-old woman who underwent a right salpingo-oophorectomy for a right ovarian bulky mass and the histopathological diagnosis was consistent with that of a malignant struma. We examine the challenges involved in the diagnosis and management of this rare entity.

scholarly journals Vogt-Koyanagi-Harada with Unilateral Clinical Presentation: A Case Report

2020 ◽  
Author(s):  
Seyedeh Maryam Hosseini ◽  
Maryam Dourandish ◽  
Marjan Mazouchi
Keyword(s):  
Case Report ◽  
Clinical Manifestations ◽  
Oral Prednisolone ◽  
Response To Treatment ◽  
Systemic Involvement ◽  
Optic Disc Swelling ◽  
Characteristic Features ◽  
The Right ◽  
Visual Blurring ◽  
Vkh Disease

Purpose: To report a case of acute Vogt-Koyanagi-Harada (VKH) disease with unilateral clinical manifestations followed by late fellow eye involvement. Case Report: This case report reviews the 12-month follow-up observation of a 44-year old woman who presented to the emergency department with unilateral progressive and painless visual blurring. Ophthalmoscopic findings, best-corrected visual acuity (BCVA), fluorescein angiography (FAG), enhanced-depth optical coherence tomography (EDIOCT), indocyanine green angiography, and response to treatment were evaluated. Her BCVA was 20/50 (logMAR: 0.4) in the right eye and 20/20 (logMAR: 0) in the left eye. Eye examination revealed optic disc swelling and multiple serous retinal detachments in the right eye and a normal left eye. She had headache, dysacusia, and mild hearing problems. Her past ocular and drug histories were unremarkable. Retinal imaging revealed characteristic features of VKH in the right eye. All laboratory testing results were inconclusive. VA and OCT findings significantly improved following the treatment with methylprednisolone 1 g/day continued by tapering dose of oral prednisolone. Two months after the presentation and during prednisolone tapering, VA of the left eye decreased and fundus examination revealed multiple serous retinal detachments in this eye. Conclusion: Ophthalmologists should recognize unilateral and asymmetrical VKH disease with subtle systemic involvement.

scholarly journals Dermatological Manifestations of COVID-19 in Children

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Vivek Athwani ◽  
Sunil Gothwal
Keyword(s):  
Toxic Shock Syndrome ◽  
Gastrointestinal Symptoms ◽  
Skin Lesions ◽  
Skin Involvement ◽  
Toxic Shock ◽  
Cutaneous Manifestations ◽  
Systemic Involvement ◽  
Atypical Kawasaki Disease ◽  
Coronavirus Infection ◽  
Inflammatory Syndrome

: Coronavirus infection 2019 (COVID-19) primarily has a respiratory system and multi-systemic involvement. Respiratory and gastrointestinal symptoms are predominantly seen in children. In adults, few COVID-19 cases are reported with cutaneous manifestations. Although children are less severely affected by COVID-19, there is increasing evidence for skin involvement, which is in the form of chilblain (e.g., lesions, vesicular, and maculopapular) and erythema multiforme (e.g., rash). Also, few COVID-19 cases are presented with a clinical picture of atypical Kawasaki disease and toxic shock syndrome, later defined as pediatric multisystem inflammatory syndrome (PMIS). The present study aims to summarize various skin lesions with COVID-19.

Sign in / Sign up

Export Citation Format

Share Document