scholarly journals Pancytopenia as a Presentation of Iron Deficiency: A Case Report

2021 ◽  
Vol 9 (2) ◽  
pp. 159-162
Author(s):  
Hossein Karami ◽  
◽  
Mohammad Naderisorki ◽  
Maryam Ghasemi ◽  
Mobin Ghazaiean ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Rare Condition ◽  
Nutritional Deficiencies ◽  
Deficiency Anemia ◽  
Main Role ◽  
Cold Intolerance ◽  
Iron Supplements ◽  
Leukocyte Counts ◽  
Symptoms And Signs

One of the most common nutritional deficiencies worldwide is iron deficiency. Fatigue, pallor, vertigo, dyspnea, cold intolerance, lethargy, palpitation, headache, and the pallor of the mucous membranes or nail beds are the most frequent symptoms and signs of iron deficiency. Thrombocytosis is commonly observed in iron deficiency anemia; it seems that erythropoietin plays the main role in this respect. Furthermore, thrombocytopenia and even leukopenia have been reported in iron deficiency; however, pancytopenia is a very rare condition. In this report, we presented two unusual cases of pancytopenia due to severe iron deficiency that improved after treatment with oral iron supplements. Iron deficiency anemia, if sufficiently severe, may be associated with reduced platelet and leukocyte counts. Accordingly, this condition should be considered as a differential diagnosis in all patients with pancytopenia.

scholarly journals Iron deficiency anemia: current strategies for the diagnosis and management

2013 ◽  
Vol 4 (3) ◽  
pp. 193-202 ◽  
Author(s):  
Zühre Kaya
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Binding Capacity ◽  
Ferritin Level ◽  
Nutritional Deficiencies ◽  
Deficiency Anemia ◽  
Iron Level ◽  
Serum Iron Level ◽  
Diagnosis And Management ◽  
Low Serum

Iron deficiency is one of the commonest nutritional deficiencies in the world. It is multifactorial and may be caused by lack of intake, blood loss and intestinal causes. Clinical features are highly variable, and most patients are asymptomatic. Typical laboratory features of iron deficiency anemia (IDA) include a hypochromic microcytic anemia, low serum iron level, high total iron binding capacity, low serum ferritin level. Usefulness of monitoring serum transferrin receptor level (sTfR) and hepcidin for identifying IDA have been examined in a few studies. Available data suggest that sTfR can potentially become a valuable tool for regular testing of patients in the future. Despite IDA is easily corrected with iron therapy, establishing the cause can be difficult, particularly in cases caused by disorders of iron transport. Education for clinician needs to focus on increasing awareness of the importance of failure respond to iron supplementation. The aim of this review was to outline the current strategies for the diagnosis and management of IDA in the light of the latest reports.

Effect of microalgae as iron supplements on iron-deficiency anemia in rats

2019 ◽  
Vol 10 (2) ◽  
pp. 723-732 ◽  
Author(s):  
Fengzheng Gao ◽  
Wei Guo ◽  
Mingyong Zeng ◽  
Yinong Feng ◽  
Guangxin Feng
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Iron Supplements ◽  
Nanosized Iron

Microalgae are functional iron nutritive fortifiers that can supply more intestinal nanosized iron.

Simultaneous determination and speciation analysis of arsenic and chromium in iron supplements used for iron-deficiency anemia treatment by HPLC-ICP-MS

Talanta ◽  
2017 ◽  
Vol 170 ◽  
pp. 523-529 ◽  
Author(s):  
Uenderson Araujo-Barbosa ◽  
Elena Peña-Vazquez ◽  
Maria Carmen Barciela-Alonso ◽  
Sergio Luis Costa Ferreira ◽  
Ana Maria Pinto dos Santos ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Simultaneous Determination ◽  
Iron Deficiency Anemia ◽  
Speciation Analysis ◽  
Deficiency Anemia ◽  
Iron Supplements ◽  
Icp Ms ◽  
Anemia Treatment

scholarly journals Effect of iron deficiency anemia on lipid peroxidation and antioxidant systems

2012 ◽  
Vol 7 (4) ◽  
pp. 34-43 ◽  
Author(s):  
NL Madhikarmi ◽  
KRS Murthy
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Binding Capacity ◽  
Lipid Hydroperoxide ◽  
Nutritional Deficiencies ◽  
Deficiency Anemia ◽  
Antioxidant Systems ◽  
Enzymatic Antioxidants

Iron deficiency is one of the most widespread nutritional deficiencies in the world. Globally more than two billion people are suffering from iron deficiency anemia. The present study was designed to investigate the influence of a large number of factors known to be associated with oxidative stress. The case-control study determines the lipid peroxidation and antioxidants status in forty Iron deficiency anemia and forty healthy volunteers with their informed consent. All the parameters were assayed by spectrophotometric methods. Blood hemoglobin and plasma iron were decreased whereas total iron binding capacity was increased significantly in Iron deficiency anemia. The lipid peroxidation parameters like malondialdehyde, lipid hydroperoxide were significantly increased in Iron deficiency anemia. Both enzymatic; glutathione peroxidase, superoxide dismutase and catalase and non-enzymatic antioxidants; vitamin C, E and reduced glutathione were significantly decreased in Iron deficiency anemia case as compared to their healthy counterparts. Our findings suggest, increased lipid peroxidation products and reduced antioxidants system boost the oxidative stress state, hence deteriorating the condition of Iron deficiency anemia patients. Journal of College of Medical Sciences-Nepal,2011,Vol-7,No-4, 34-43 DOI: http://dx.doi.org/10.3126/jcmsn.v7i4.6739

scholarly journals Iron Deficiency and Schooling Attainment in Peru

2016 ◽  
Vol 8 (4) ◽  
pp. 222-255 ◽  
Author(s):  
Alberto Chong ◽  
Isabelle Cohen ◽  
Erica Field ◽  
Eduardo Nakasone ◽  
Maximo Torero
Keyword(s):  
Iron Deficiency ◽  
Health Center ◽  
School Performance ◽  
Administrative Data ◽  
Iron Deficiency Anemia ◽  
Low Cost ◽  
Future Generations ◽  
Nutritional Deficiencies ◽  
Deficiency Anemia ◽  
Media Messages

Do nutritional deficiencies contribute to the intergenerational persistence of poverty by reducing the earnings potential of future generations? To address this question, we made available supplemental iron pills at a health center in rural Peru and encouraged adolescents to take them via media messages. School administrative data provide novel evidence that reducing iron deficiency results in a large and significant improvement in school performance and aspirations for anemic students. Our findings demonstrate that combining low-cost outreach efforts and local supplementation programs can be an affordable and effective method of reducing rates of adolescent iron deficiency anemia. (JEL I21, I23, I26, J24, J31, Q51, Q53)

scholarly journals Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qi Zhang ◽  
Xiao-Min Lu ◽  
Min Zhang ◽  
Chen-Ying Yang ◽  
Si-Yuan Lv ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Adverse Effects ◽  
Iron Deficiency Anemia ◽  
Light Chain ◽  
Pregnancy Outcomes ◽  
Iron Supplementation ◽  
Female Rats ◽  
Physical Growth ◽  
Deficiency Anemia ◽  
Iron Supplements

AbstractIron deficiency anemia (IDA) is a common micronutrient deficiency among pregnant women with severe consequences including impaired immuno-inflammatory system, premature birth, fetal death etc. The present study aimed to investigate the effects of three iron supplements on IDA female rats and their offspring. The IDA female rat model was established with low iron diet and the rats were then mated. After pregnancy, rats were fed diets containing different iron supplements (iron polysaccharide complex, iron protein succinylate and ferrous sulfate) until their offspring were 42 days old. Pregnancy outcomes, haematological, iron metabolism, physical and neurological development indexes were determined. The results showed that all three iron supplements improved the levels of hematological parameters of both mother and offspring rats. After iron supplementation, serum iron, transferrin saturation and serum ferritin levels were increased compared with the IDA group. The level of ferritin light chain in the liver and spleen of both mother and offspring rats in iron supplemented groups was significantly higher than that of the IDA group. The average number of born alive per litter in the iron treatment groups was significantly higher than that in the IDA group. Iron supplements also improved the physical growth and neurobehavioral development of offspring rats. It was also found that iron supplementation improved the expression of ferritin light chain and the synaptic growth associated proteins in the brain and hippocampus. No significant difference was found in the efficacy of three iron supplements. These results suggest that pregnant and postpartum IDA affects pregnancy outcomes, offspring physical development and causes neural impairment. Sufficient iron supplementation can significantly improve IDA and its adverse effects on both mother and offspring.

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