Ekspresi cyclooxygenase-2 (COX-2) pada penderita rinosinusitis kronis

Background: Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus mucosa, which are closely related to the involvement of ostiomeatal complex as the drainage pathway of of maxillary and frontal sinuses. Inflammation or edema at the ostiomeatal complex could cause drainage problems leading to rhinosinusitis. Increased expression of COX-2 regulation was considered to play an important role in the development of CRS and increased airway inflammation in the nasal mucosa and paranasal sinuses. Purpose: To find out the expression of Cyclooxygenase-2 in our CRS patients. Methods: This descriptive research was conducted on July 2011 - December 2011 at ENT Department and Pathology Anatomy Department of Medical Faculty of Sumatera Utara University/H. Adam Malik General Hospital, Medan, to all patients diagnosed with CRS and underwent sinus surgery on July 2011 - December 2011. Results: The highest proportion of pain in patients with CRS is facial pain/pressure and headache with nasal congestion which was 78.6%. Multisinusitis on paranasal sinus CT scan was 88.0%. There was a significant correlation between the proportion of pain with the expression of COX-2 (p = 0.033). There was a significant correlation in proportion between the number of sinuses involved with the expression of COX-2 (p = 0.002). Conclusion: This study found positive expression of COX-2 was 84,0%, while negative expression was 16,0% in our rhinosinusitis patients. This lead to conclusion that upregulation of COX-2 expression is thought to play a role as a mediator in the development of CRS. Keywords: chronic rhinosinusitis, ostiomeatal complex, cyclooxygenase-2, immunohistochemical. Abstrak : Latar belakang: Rinosinusitis kronis merupakan peradangan mukosa hidung dan sinus paranasal yang erat hubungannya dengan keterlibatan kompleks ostiomeatal atau celah sempit di etmoid anterior, yang merupakan serambi muka bagi sinus maksila dan frontal. Bila terdapat gangguan di daerah kompleks ostiomeatal seperti inflamasi atau edema maka hal itu akan menyebabkan gangguan drainase sehingga terjadi rinosinusitis. Peningkatan regulasi ekspresi COX-2 diperkirakan memegang peran penting sebagai mediator dalam terjadinya rinosinusitis kronis dan peningkatan inflamasi saluran napas di mukosa hidung dan sinus paranasal. Tujuan: Mengetahui ekspresi cyclooxygenase-2 pada penderita rinosinusitis kronis di RSUP H. Adam Malik, Medan. Metode: Penelitian ini bersifat deskriptif dilakukan di Departemen THT-KL FK USU/RSUP H. Adam Malik, Medan dan Departemen Patologi Anatomi FK USU. Penelitian dilakukan bulan Juli - Desember 2011 pada seluruh penderita yang didiagnosis rinosinusitis kronis, yang menjalani operasi sinus di Divisi Rinologi Departemen THT-KL FK USU/RSUP H. Adam Malik, Medan bulan Juli 2011 - Desember 2011. Hasil: Proporsi rasa nyeri terbanyak pada penderita rinosinusitis kronis adalah rasa nyeri/ nyeri tekan wajah, sakit kepala disertai dengan hidung tersumbat 78,6%. Multi sinusitis pada pemeriksaan CT-Scan sinus paranasal sebanyak 88,0%. Ada hubungan yang bermakna antara jumlah sinus yang terlibat dengan ekspresi COX-2 (p = 0,002). Ada hubungan yang bermakna antara proporsi rasa nyeri dengan ekspresi COX-2 (p=0,033). Kesimpulan: Pada penelitian ini didapati pada penderita rinosinusitis kronis, ekspresi COX-2 yang positif yaitu sebanyak 84,0%, sedangkan yang negatif sebanyak 16,0%. Diperkirakan peningkatan regulasi ekspresi COX-2 berperan sebagai mediator dalam terjadinya rinosinusitis kronis. Kata Kunci: rinosinusitis kronis, kompleks ostiomeatal, cyclooxygenase-2, imunohistokimia.

Download Full-text

Machine-Learning Points at Endoscopic, Quality of Life, and Olfactory Parameters as Outcome Criteria for Endoscopic Paranasal Sinus Surgery in Chronic Rhinosinusitis

Journal of Clinical Medicine ◽

10.3390/jcm10184245 ◽

2021 ◽

Vol 10 (18) ◽

pp. 4245

Author(s):

Jörn Lötsch ◽

Constantin A. Hintschich ◽

Petros Petridis ◽

Jürgen Pade ◽

Thomas Hummel

Keyword(s):

Quality Of Life ◽

Machine Learning ◽

Chronic Rhinosinusitis ◽

Paranasal Sinus ◽

Endoscopic Sinus Surgery ◽

Relevant Information ◽

Olfactory Function ◽

Sinus Surgery ◽

Paranasal Sinus Surgery

Chronic rhinosinusitis (CRS) is often treated by functional endoscopic paranasal sinus surgery, which improves endoscopic parameters and quality of life, while olfactory function was suggested as a further criterion of treatment success. In a prospective cohort study, 37 parameters from four categories were recorded from 60 men and 98 women before and four months after endoscopic sinus surgery, including endoscopic measures of nasal anatomy/pathology, assessments of olfactory function, quality of life, and socio-demographic or concomitant conditions. Parameters containing relevant information about changes associated with surgery were examined using unsupervised and supervised methods, including machine-learning techniques for feature selection. The analyzed cohort included 52 men and 38 women. Changes in the endoscopic Lildholdt score allowed separation of baseline from postoperative data with a cross-validated accuracy of 85%. Further relevant information included primary nasal symptoms from SNOT-20 assessments, and self-assessments of olfactory function. Overall improvement in these relevant parameters was observed in 95% of patients. A ranked list of criteria was developed as a proposal to assess the outcome of functional endoscopic sinus surgery in CRS patients with nasal polyposis. Three different facets were captured, including the Lildholdt score as an endoscopic measure and, in addition, disease-specific quality of life and subjectively perceived olfactory function.

Download Full-text

Study of the effect of balloon sinuplasty in patients with rhinosinusitis

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20204622 ◽

2020 ◽

Vol 6 (11) ◽

pp. 2007

Author(s):

Tanya Singh ◽

Arjun Singh ◽

Sarbjeet Singh

Keyword(s):

Chronic Rhinosinusitis ◽

Sinus Surgery ◽

Saline Irrigation ◽

Balloon Sinuplasty ◽

Positive Biopsy ◽

Intravenous Antibiotics ◽

Nasal Steroids ◽

Frontal Sinuses ◽

A New Technique

Background: A new technique which has revolutionized sinus surgery recently is balloon sinuplasty. The vast majority of patients with chronic rhinosinusitis improve with medical management, including antibiotics, saline irrigation, nasal steroids, antihistamines, allergy therapy, and asthma control. This study was conducted to study the effect of balloon sinuplasty in patients affected with rhinosinusitis.Methods: This prospective study was conducted in all the patients visiting our hospital. Medical treatment included oral and sometimes intravenous antibiotics, nasal steroids, decongestants, systemic steroids, and allergy management. Those who had a positive biopsy were excluded from this study. The selected cohort of 20 patients, were prepared for balloon sinuplasty surgery in the same way as for conventional functional endoscopic sinus surgery (FESS) and were operated by our surgical team. Results: 20 patients were included in the study, 70% men and aged 30±12 years. Sinuplasty was performed in 32 sinuses of 20 patients (22 maxillary, 4 sphenoid and 8 frontal sinuses).Conclusions: Sinuplasty with balloon catheterization is effective in reducing symptoms and improving quality of life in selected patients with chronic rhinosinusitis. The results are beyond reported symptoms and confirm the benefit of balloon sinuplasty.

Download Full-text

Anatomic Variations of the Nose in Chronic Rhinosinusitis: Correlation between Nasal Endoscopic and Computerized Tomography Scan Findings and a Review of Literature

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1255 ◽

2016 ◽

Vol 9 (1) ◽

pp. 13-17

Author(s):

Priyanko Chakraborty ◽

Rajiv K Jain ◽

Purnima Joshi ◽

Rakhi Kumari ◽

Sidharth Pradhan

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Chronic Rhinosinusitis ◽

Sinus Surgery ◽

Anatomic Variations ◽

Review Of Literature ◽

Computed Tomography Scan ◽

Diagnostic Endoscopy ◽

The Mean ◽

Tomography Scan

ABSTRACT Background Chronic rhinosinusitis (CRS) refers to a group of disorders characterized by inflammation of the mucosa of the paranasal sinuses. Nasal endoscopy and computed tomography (CT) scans are successfully used as diagnostic modalities of nose and paranasal sinus diseases. There have been many studies regarding the anatomic variations leading to pathogenesis of paranasal sinus diseases. Considerable progress has been made in the medical and surgical control of these conditions; however, a large number of questions relating to the diagnosis, evaluation, and treatment of the diseases remain unanswered. Materials and methods The study included 82 clinically diagnosed cases of CRS who underwent CT scan and were advised to undergo diagnostic endoscopy. The anatomical findings of the nose were compared to see correlation between nasal endoscopy and CT scan. Results The mean age (±standard error of the mean) of presentation was 34.11 (±1.42) years, while most patients were from the age group of 18 to 30 years. Males were predominating the study group with 62.2%, while 37.8% were females. The most common anatomic variation was deviated nasal septum with 92.68% CT reported patients. This was followed by inferior turbinate hypertrophy, septal spur, concha bullosa, and agger nasi cells. Conclusion Computed tomography scan is considered the gold standard for sinonasal imaging. Diagnostic endoscopy and CT scan are a must prior to any functional endoscopic sinus surgery. They help in assessing the extent of sinus disease and to know the variations and vital relations of the paranasal sinuses. Computed tomography scan assists the surgeon as a “road map” during endoscopic sinus surgery. How to cite this article Chakraborty P, Jain RK, Joshi P, Kumari R, Pradhan S. Anatomic Variations of the Nose in Chronic Rhinosinusitis: Correlation between Nasal Endoscopic and Computerized Tomography Scan Findings and a Review of Literature. Clin Rhinol An Int J 2016;9(1):13-17.

Download Full-text

Pathomorphological Features of the Mucoperiostasis of the Processus Uncinatus in Discrete Diseases of the Maxillary Sinus

Ukraïnsʹkij žurnal medicini bìologìï ta sportu ◽

10.26693/jmbs06.05.255 ◽

2021 ◽

Vol 6 (5) ◽

pp. 255-262

Author(s):

Ya. V. Shkorbotun ◽

◽

O. G. Kuryk ◽

◽

Keyword(s):

Maxillary Sinus ◽

Chronic Rhinosinusitis ◽

Nasal Polyps ◽

Sinus Surgery ◽

Histological Features ◽

Dental Implantation ◽

Ostiomeatal Complex ◽

History Of ◽

Group 3 ◽

Group 2

The state of the mucoperiostasis of the maxillary sinus is one of the important factors that affect the effectiveness of dental implantation, especially in case of need for augmentation of the maxillary bone. Chronic rhinosinusitis with nasal polyps, chronic rhinosinusitis with fungal bodies, and sinus cysts are among the most common pathological processes in the maxillary sinus that are encountered when performing subantral augmentation. In addition, a separate category of patients is made up of those with a history of sinus surgery in their anamnesis. The condition of sinus mucoperiosteum can be estimated based on results of processus uncinatus research, because it has a similar histological structure, directly contacts with all maxillary sinus excretion and, as usual, gets removed while endoscopic sinusotomy. The purpose of the work was to study the histological features of mucoperiostasis and adjacent bone in the ostiomeatal complex in discrete diseases of paranasal sinuses: chronic rhinosinusitis with nasal polyps, maxillary sinus cysts, fungal balls and postoperative scar changes in the ostium. Materials and methods. Histological features of processus uncinatus fragments removed during endoscopic interventions in 45 patients were investigated: with sinus cysts – 12 patients (group 1), chronic rhinosinusitis with nasal polyps – 13 patients (group 2), sinus fungal body – 13 patients (group 3) and postoperative scarring changes in the ostiomeatal complex – 7 patients. The condition of the epithelial layer of the mucoperiosteum, the structure of its own plate, the periosteal layer and the bone to be treated were evaluated. Results and discussion. In 91.67 ± 0.08% of patients with maxillary sinus cysts, there were no changes in the mucoperiostasis and the bone of processus uncinatus. Most patients in groups 2 and 3 showed mucoperiostal edema with a predominant reaction of the mucosal layer and lamina propria. Fibrous changes of the processus uncinatus were most often detected after the intervention was performed at 71.43 ± 0.13% and in chronic rhinosinusitis with nasal polyps – 53.85 ± 0.14%. This confirms the significance of the mucoperiostasis injury factor with the underlying bone for the development of gross adhesive changes between the periosteum and bone tissue. Osteitis of the processus uncinatus was detected in 38.46 ± 0.13% of patients in group 2, 15.38 ± 0.1% in group 3, and 28.57 ± 0.17% in group 4. Conclusion. Signs of periostitis and processus uncinatus osteitis were most often detected in patients with neutrophilic mucoperiosteum infiltration in chronic rhinosinusitis with nasal polyps and in fungal balls sinus. History of surgery with periosteal and bone trauma promotes scarring and results in a tight connection between bone and periosteum, which can be regarded as a risk factor in relation to the rupture of the later in its peeling off during sinus lifting procedure. Therefore, when performing surgery on the maxillary sinus, in order to maintain conditions for possible dental implantation, excessive trauma of the periosteal layer of mucoperiosteum should be avoided

Download Full-text

Hubungan Gambaran Histopatologi Dan Derajat Konka Hipertrofi Dengan Sumbatan Hidung Pada Rinosinustis Kronik

Medica Hospitalia : Journal of Clinical Medicine ◽

10.36408/mhjcm.v7i2.516 ◽

2020 ◽

Vol 7 (2) ◽

pp. 427-431

Author(s):

Anna Mailasari Kusuma Dewi ◽

Rano Aditomo ◽

Riece Hariyati ◽

Meira Dewi Kusuma Astuti

Keyword(s):

Chronic Rhinosinusitis ◽

Nasal Obstruction ◽

Histopathological Examination ◽

Hypothesis Test ◽

Nasal Congestion ◽

Choanal Atresia ◽

Sinus Surgery ◽

Histopathological Features ◽

Turbinate Hypertrophy ◽

Symptom Evaluation

Latar belakang : Hidung tersumbat dapat disebabkan karena kelainan struktur hidung seperti deviasi septum, atresia koana, konka hipertrofi, celah palatum, hipertrofi adenoid, dan neoplasma. Dua puluh persen populasi dengan hidung tersumbat disebabkan konka hipertrofi. Konka hipertrofi merupakan pembesaran konka akibat bertambahnya ukuran sel konka, yang disebabkan hiperplasia dan hipertrofi lapisan mukosa dan tulang konka. Gambaran hipertrofi dan hiperplasi dapat dilihat melalui pemeriksaan histopatologi. Tujuan penelitian ini untuk mengetahui hubungan gambaran histopatologi dan derajat konka hipertrofi dengan sumbatan hidung pada pasien rinosinusitis kronik (RSK). Metode : Desain penelitian korelasi dengan metode belah lintang pada pasien RSK dengan konka hipertrofi yang menjalani operasi Bedah Sinus Endoskopik Fungsional (BSEF) dan konkotomi. Derajat konka hipertrofi dinilai berdasarkan nasoendoskopi, sedangkan sumbatan hidung menggunakan kuesioner Nasal Obstruction Symptom Evaluation (NOSE). Uji hipotesis yang digunakan adalah uji korelasi Spearman. Hasil : Karakteristik subyek penelitian sebanyak 33 orang, perempuan 60% lebih banyak daripada laki-laki 40%. Derajat sumbatan hidung ringan (30%), sedang (27%), berat (30%) dan sangat berat (13%). Konka hipertrofi terbanyak yaitu derajat 3 (54,5%). Hasil analisis dengan uji korelasi Spearman menunjukkan terdapat korelasi positif dengan nilai korelasi sedang antara derajat konka hipertrofi dengan derajat sumbatan hidung (p=0.02 dan rho = 0.404. Tidak terdapat hubungan yang bermakna antara derajat sumbatan hidung dengan gambaran histopatologi konka inferior (hiperplasia sel goblet, pembentukan kelenjar submukosa, eosinofil, limfosit, neutrofil). Simpulan : Derajat konka hipertrofi berpengaruh terhadap sumbatan hidung. Gambaran histopatologi konka hipertrofi tidak berpengaruh terhadap derajat sumbatan hidung pada pasien RSK. Kata kunci : Rinosinusitis kronik, sumbatan hidung, konka hipertrofi Background: Nasal congestion can be caused by abnormalities of nasal structures such as deviation of the septum, choanal atresia, turbinate hypertrophy, cleft palate, adenoid hypertrophy, and neoplasms. Twenty percent of the population with nasal congestion is due to turbinate hypertrophy. Turbinate hypertrophy is an enlargement of turbinate due to an increase in the size of turbinate cells, which is caused by hyperplasia and hypertrophy of the mucosal layers and turbinate bones. Description of hypertrophy and hyperplasia can be seen through histopathological examination. The purpose of this study was to determine the relationship between histopathological features and the degree of turbinate hypertrophy with nasal obstruction in patients with chronic rhinosinusitis (CRS). Methode: The correlative study design with a cross-sectional method in CSR patients with turbinate hypertrophy who underwent Functional Endoscopic Sinus Surgery (FESS) and turbinectomy. The degree of turbinate hypertrophy was assessed based on nasoendoscopy, whereas nasal obstruction used the Nasal Obstruction Symptom Evaluation (NOSE) questionnaire. The hypothesis test used is the Spearman correlation test. Result: The characteristics of the study subjects were 33 people, more women (60%) than men (40%). The degree of nasal obstruction is mild (30%), moderate (27%), severe (30%) and very severe (13%). Turbinate hypertrophy grade 3 was the most (54,5%). The analyzed using Spearman correlative test showed a positive correlation with a moderate correlation between the degree of turbinate hypertrophy with the degree of nasal obstruction (p=0.02 dan rho = 0.404). There was no significant relationship between the degree of nasal obstruction with histopathological features of the inferior turbinate (goblet cell hyperplasia, the formation of submucosal glands, eosinophils, lymphocytes, and neutrophils). Conclusion: The degree of turbinate hypertrophy affects nasal obstruction. Histopathological features of turbinate hypertrophy do not affect the degree of nasal obstruction in CSR patients. Keyword: Chronic rhinosinusitis, nasal obstruction, turbinate hypertrophy

Download Full-text

Eosinophilia in the Ethmoid Mucosa and Its Relationship to the Severity of Inflammation in Chronic Rhinosinusitis

American Journal of Rhinology ◽

10.1177/194589240201600301 ◽

2002 ◽

Vol 16 (3) ◽

pp. 131-134 ◽

Cited By ~ 38

Author(s):

Eva Szucs ◽

Saied Ravandi ◽

Anita Goossens ◽

Mieke Beel ◽

Peter A.R. Clement

Keyword(s):

Ct Scan ◽

Chronic Rhinosinusitis ◽

Staging System ◽

Inflammatory Cells ◽

Sinus Surgery ◽

Mucosal Inflammation ◽

Tissue Eosinophilia ◽

Eosinophilic Infiltrate ◽

Preoperative Ct ◽

Sinus Mucosa

Background The aim of this study was to analyze histopathologically mucosal inflammation in patients with chronic rhinosinusitis. In addition, we assessed tissue eosinophilia in relation to the severity of inflammation and to the computer tomographic (CT) findings. Methods Forty-eight pathological sinus mucosa specimens obtained during functional endoscopic sinus surgery were stained by hematoxylin and eosin. Total inflammatory cells and eosinophils were quantified. The preoperative CT scans were scored by the staging system of Lund-MacKay. Results The grade of the eosinophilic infiltration in the diseased sinus mucosa correlated significantly with the severity of the mucosal inflammation. Allergy or asthma had no effect on the proportion of the eosinophilic infiltrate. The CT scan scores assessed by the Lund-MacKay system correlated significantly with the severity of the inflammatory cellular infiltrate. The correlation between the CT scan scores and the eosinophilic infiltrate of the mucosa was close to significant. Conclusion Eosinophilic mucosal inflammation represents the most severe inflammatory changes of the mucosa. Twenty to forty percent of the patients with chronic rhinosinusitis had no eosinophilic inflammation of the mucosa. The CT-staging system of Lund-Mackay correlated with the extent of mucosal inflammation.

Download Full-text

Combined Image Guidance and Intraoperative Computed Tomography in Facilitating Endoscopic Orientation within and around the Paranasal Sinuses

American Journal of Rhinology ◽

10.2500/ajr.2008.22.3242 ◽

2008 ◽

Vol 22 (6) ◽

pp. 635-641 ◽

Cited By ~ 21

Author(s):

Sarah K. Wise ◽

Richard J. Harvey ◽

John C. Goddard ◽

Patrick O. Sheahan ◽

Rodney J. Schlosser

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Paranasal Sinus ◽

Image Guidance ◽

Sinus Surgery ◽

Intraoperative Ct ◽

Intraoperative Computed Tomography ◽

Significant Difference ◽

Preoperative Ct ◽

Anatomic Region

Background The utility of image guidance (image-guided surgery [IGS]) and intraoperative computed tomography (CT) scanning as a tool for less experienced endoscopic surgeons to aid in localization of paranasal sinus and skull base anatomic structures was evaluated. Methods Partial endoscopic dissection was performed on cadaver specimens by three fellowship trained rhinologists. Anatomic sites within and around the sinuses were tagged with radio-opaque markers. Otolaryngology residents identified tagged anatomic sites using four successive levels of technology: endoscopy alone (simulating outpatient clinic), endoscopy plus preoperative CT (simulating endoscopic sinus surgery [ESS] without IGS), endoscopy plus IGS registered to preoperative CT (simulating current ESS with IGS), and endoscopy plus IGS registered to real-time intraoperative CT. Responses were graded as follows: consensus rhinologist answer (4 points), close answer without clinically significant difference (3 points), within anatomic region but definite clinical difference (2 points), outside of anatomic region (1 point), no answer (0 points). Results Eleven residents participated. Of 20 specific anatomic sites, IGS-intraoperative CT provided the most accurate anatomic identification at 16 sites. For 8 sites, IGS-intraoperative CT had a significantly higher score than endoscopy alone (p < 0.05; eta2 = 0.29-0.67). For 6 sites, IGS-preoperative CT scan had a significantly higher score than endoscopy alone (p < 0.05; eta2 = 0.30-0.67). All participants found that IGS-intraoperative CT scan made them most comfortable in identifying anatomy. Conclusion Combined IGS and intraoperative CT scan technology may be an instructional adjunct for less experienced paranasal sinus surgeons for dissection and evaluation of unfamiliar or distorted anatomy.

Download Full-text

Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps

European Archives of Oto-Rhino-Laryngology ◽

10.1007/s00405-014-3481-9 ◽

2015 ◽

Vol 272 (12) ◽

pp. 3715-3720 ◽

Cited By ~ 10

Author(s):

Jarosław Miłoński ◽

Hanna Zielińska-Bliźniewska ◽

Karolina Przybyłowska ◽

Piotr Pietkiewicz ◽

Barbara Korzycka-Zaborowska ◽

...

Keyword(s):

Gene Expression ◽

Chronic Rhinosinusitis ◽

Nasal Polyps ◽

Cyclooxygenase 2 ◽

Interleukin 4 ◽

Cox 2

Download Full-text

The utilization of paranasal sinus coronal tomography scans as a predictor for the anterior ethmoidal artery course.

10.21203/rs.3.rs-16342/v1 ◽

2020 ◽

Author(s):

Hasan Al-Balas ◽

Amjad Nuseir ◽

Firas Alzoubi ◽

Ahmad Alomari ◽

Bayan Al-Balas ◽

...

Keyword(s):

Ct Scan ◽

Paranasal Sinus ◽

Preoperative Evaluation ◽

University Hospital ◽

Sinus Surgery ◽

Face Images ◽

The Face ◽

Ethmoidal Artery ◽

Anterior Ethmoidal Artery ◽

Ethmoid Labyrinth

Abstract Background. This study aims to identify radiological features on paranasal sinus coronal tomography images that can guide the surgeon to localize and determine the course of the anterior ethmoidal artery (AEA). These features include the visualization of anterior ethmoidal foramen (AEF) and anterior ethmoidal sulcus (AES) as well as the supraorbital pneumatization (SOP). Methods. This retrospective study includes 182 of the paranasal sinuses coronal tomography (CT) for patients who attended the clinic from January 2019 to August 2019 in King Abdullah University Hospital. We excluded the following images from our study: patients younger than twelve years old, patients with a sinus surgery record or trauma, patients with sinus malignancies, congenital anomalies of the face, images with fibro-osseous lesions that impaired the visualization of ethmoid roof, and images with opacified frontal recess region and/or the ethmoidal cells.Results. Both AEF and AES are prominent features on the coronal CT scan that are used to localize the AEA canal and predict its course in the ethmoid labyrinth. It was found that both radiological landmarks are presented in 100% and 93.4 % of our cases; respectively. Moreover, the presence of SOP is significant with the existence of AEA canal on coronal CT scan images.Conclusion. The preoperative evaluation of a coronal CT scan to localize the AEA can be precisely determined by visualization of both the AEF and AES. On the other hand, the presence of SOP is considered a significant sign on the CT scan were AEA can be identified.

Download Full-text

Korelasi Skor Lund-Mackay dan Volume Cairan Sinus Berdasarkan Gambaran CT-Scan Sinus Paranasalis 3D dengan Skor SNOT-22 pada Pasien RSK Tanpa dan dengan Polip

Majalah Sainstekes ◽

10.33476/ms.v6i2.1201 ◽

2019 ◽

Vol 6 (2) ◽

Author(s):

Muhammad Ridha Maulana ◽

Nurlaily Idris ◽

Nikmatia Latief ◽

Burhanuddin Bahar ◽

Muhammad Fadjar Perkasa ◽

...

Keyword(s):

Ct Scan ◽

Chronic Rhinosinusitis ◽

Paranasal Sinus ◽

Fluid Volume ◽

University Hospital ◽

3D Ct ◽

Snot 22

The aim of this study is to determine the correlation between Lund-Mackay scores and sinus fluid volume based on 3D CT paranasal sinus scan with SNOT-22 score in patients with chronic rhinosinusitis without and with polyps. This research was conducted at the Department of Radiology Hasanuddin University Hospital Makassar from April to June 2019. Samples were 38 patients without and with polyps in age ? 18 years. The method used is the Spearman rho test. The results showed a correlation between sinus fluid volume and SNOT-22 score in patients with chronic rhinosinusitis without polyps n = 25, p = 0.042 (p 0.05), the higher the sinus fluid volume, means the SNOT-22 score was higher in patients with chronic rhinosinusitis without polyps. There was no correlation between sinus fluid volume and SNOT-22 score in patients with chronic rhinosinusitis with polyps n = 13, p = 0.077 (p 0.05), there was not any correlation between Lund-Mackay scores and SNOT-22 scores in patients with chronic rhinosinusitis without and with polyps.

Download Full-text