Urinary tract abnormalities in children with first urinary tract infection

Abstract Urinary tract infection (UTI) caused by bacterial pathogens of the respiratory tract such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis is rare and little is known about their characteristics and potential host risk factors. We conducted a retrospective descriptive study on pediatric UTI due to S. pneumoniae, Haemophilus spp., or M. catarrhalis at a tertiary-care pediatric hospital. Pediatric patients with diagnosed UTI between 2002 and 2020 were included. Patient demographics, laboratory data, and microbiological findings were extracted from their electronic medical records and the infectious disease surveillance system. Among 46,332 urine samples, 76 bacteriuria (0.16%) and 22 UTI (0.05%) events due to the targeted species were identified (S. pneumoniae [n=7] and Haemophilus spp. [n=15]). Of the patients, 17 (85%) had underlying urinary tract abnormalities and 13 (60%) had vesicocutaneous fistula. All the UTI episodes caused by S. pneumoniae and Haemophilus spp. occurred after cystostomy. All the patients had satisfactory clinical outcomes.Conclusion: Although S. pneumoniae and Haemophilus spp. are rare causes of UTI in children, they could be the true causative bacteria of UTI even when detected in urine specimens, particularly in the patients with urinary tract abnormalities and vesicocutaneous fistula.

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COHORT STUDY OF BACTERIAL SPECIES CAUSING URINARY TRACT INFECTION AND URINARY TRACT ABNORMALITIES IN CHILDREN.

The Pediatric Infectious Disease Journal ◽

10.1097/00006454-199908000-00029 ◽

1999 ◽

Vol 18 (8) ◽

pp. 750

Author(s):

&NA;

Keyword(s):

Urinary Tract Infection ◽

Cohort Study ◽

Urinary Tract ◽

Tract Infection ◽

Bacterial Species ◽

Urinary Tract Abnormalities

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The incidence of urinary tract infections in febrile children during a two-year period in Tehran, Iran

Tropical Doctor ◽

10.1258/td.2008.070356 ◽

2008 ◽

Vol 38 (4) ◽

pp. 247-249 ◽

Cited By ~ 4

Author(s):

Yunes Panahi ◽

Fatemeh Beiraghdar ◽

Yashar Moharamzad ◽

Zahra Khalili Matinzadeh ◽

Behzad Einollahi

Keyword(s):

Escherichia Coli ◽

Developing Countries ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Voiding Cystourethrogram ◽

University Hospitals ◽

Urinary Tract Abnormalities ◽

Tract Infections

Of 433 febrile children examined in the paediatric clinics of two university hospitals in Tehran, Iran, 39 (9%) children (27 girls and 12 boys) were diagnosed as having urinary tract infection in which Escherichia coli was the most frequently detected pathogen (84.6%). According to the voiding cystourethrogram, nine (75%) boys and 17 (63%) girls had urinary tract abnormalities. This result is slightly higher than seen in other reports from developing countries.

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Cohort study of bacterial species causing urinary tract infection and urinary tract abnormalities in children

BMJ ◽

10.1136/bmj.318.7186.770 ◽

1999 ◽

Vol 318 (7186) ◽

pp. 770-771 ◽

Cited By ~ 35

Author(s):

O. Honkinen ◽

O.-P. Lehtonen ◽

O. Ruuskanen ◽

P. Huovinen ◽

J. Mertsola

Keyword(s):

Urinary Tract Infection ◽

Cohort Study ◽

Urinary Tract ◽

Tract Infection ◽

Bacterial Species ◽

Urinary Tract Abnormalities

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The effect of circumcision on urinary tract infection and growth in infants without any detected postnatal urinary tract abnormalities despite antenatal diagnosis of hydronephrosis

Journal of Dr Behcet Uz Children s Hospital ◽

10.5222/buchd.2013.023 ◽

2013 ◽

Vol 3 (1) ◽

pp. 23-27

Author(s):

Engin Kose ◽

Seda Sirin Kose ◽

Ozlem Pehlivan ◽

Caner Alparslan ◽

Murat Kangın ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Antenatal Diagnosis ◽

Urinary Tract Abnormalities

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The causative microorganisms and the underlying urological anomalies in children with urinary tract infection

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20182575 ◽

2018 ◽

Vol 5 (4) ◽

pp. 1614

Author(s):

Minakshi Bhat

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Renal Scarring ◽

Posterior Urethral Valve ◽

Tertiary Hospital ◽

Cystic Kidney ◽

Causative Organism ◽

Imaging Studies ◽

Urinary Tract Abnormalities

Background: Urinary tract infection (UTI) is among the most common bacterial infection in children and may be a presentation of variety of underlying urinary tract abnormalities. It is important to diagnose and treat UTI to prevent the long-term complications like renal scarring, hypertension and chronic renal failure. The aim of this study was to find the causative organism and underlying urological anomalies in children with UTI.Methods: A prospective study was carried in children (aged between one month to 12 years) admitted with symptomatic UTI in a tertiary hospital from May 2013 to June 2017.The children were investigated for UTI and the urine culture was positive in 121 patients. The confirmed cases of UTI were subjected to imaging studies as per guidelines. Final study included 116 patients as five patients were excluded due to incomplete investigations.Results: Out of 116 patients, 26 (22.41%) were below 1year ,68 (58.62%) were between 1 to 5 year and 22 (18.96%) were more than 5 years of age. There were 44 (37.93%) males and 72 (62.06%) females. E. coli was the commonest organism causing UTI (78.44%). Urinary tract abnormalities were found in 49 (42.24%) cases. VUR was detected in 23 (46.9%). The other urinary tract abnormalities observed include pelviureteric junction (PUJ) obstruction, posterior urethral valve, urolithiasis, bladder neck obstruction, ureterocele, ectopic kidney, cystic kidney, bladder diverticulum, Extrarenal pelvis, and renal scar respectively.Conclusions: In view of underlying urological anomalies and potential for renal parenchymal damage, UTI should be diagnosed at an earliest and imaging studies should be done in all confirmed cases as per guidelines.

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A hospital epidemic caused by a gentamicin-resistantKlebsiella aerogenes

Journal of Hygiene ◽

10.1017/s0022172400053432 ◽

1978 ◽

Vol 80 (1) ◽

pp. 115-123 ◽

Cited By ~ 59

Author(s):

Kathleen Curie ◽

D. C. E. Speller ◽

Rosemary A. Simpson ◽

Mary Stephens ◽

P. I. Cooke

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Clinical Manifestation ◽

Control Measures ◽

Klebsiella Aerogenes ◽

Urinary Tract Abnormalities ◽

Elderly Males ◽

Focus Of Infection ◽

Serotype K2

SUMMARYIn the 15 months, February 1976 to April 1977, more than 241 patients became colonized with a strain ofKlebsiella aerogenes, capsular serotype K2, resistant to most antibiotics. Urinary tract infection was the most common clinical manifestation but bacteraemia and, occasionally, infections of other sites were encountered. The main reservoir of the epidemic klebsiella was the gut, urine and skin of colonized patients. Gut carriage among staff was very uncommon. The most susceptible patients were elderly males, with debilitating illnesses and urinary tract abnormalities, especially if they were catheterized or receiving antibiotics. Likely vehicles for spread were the hands of staff, and contaminated bedpans and urinals. Control measures were directed at these factors. At the end of April 1977 no new cases had occurred for 3 months in the ward in which the outbreak began, and which had been the main focus of infection, and only 5 patients in the affected hospitals were known to be colonized by the epidemic klebsiella.

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