scholarly journals Expression of Tenascin in the Uterosacral Ligament is Stronger in Women with Pelvic Organ Prolapse

Author(s):  
Eny Lusiadewi

Objective: This study aimed to compare the expression of tenascin uterosacral ligament in women with and without pelvic organ prolapsen (POP). Methods: The research was carried out in Dr. Wahidin Sudirohusodo Hospital and other educational hospitals of obstetrics and gynecology division UNHAS Faculty of Medicine, which began on January 1st, 2011 until April 2012. This study assessed the expression of tenascin in 35 women with POP levels III and IV, and the controls were 35 women without POP. Tenascin expression was assessed by immunohistochemical examination using tenascin antibody staining (mouse monoclonal antibody Novacastra tenascin C, code NCL-Tenas C). The research was carried out cross sectional. Sampling was done by consecutive sampling. Data processed by the chi-square. The significance level used was 0.05. Results: The results showed that the characteristics of research subjects based on age, education, parity, labor history, history of big babies, not statistically significant. This indicates that the variable does not affect the calculation of the research data. While the characteristics of menopausal status and body mass index (BMI), from the analysis of risk factors for POP is associated significantly with a higher intensity of tenascin in post-menopausal status and BMI> 25 (overweight) (p

Author(s):  
Y. Widyastuti Y. Widyastuti

ABSTRACT Preeclampsia is a disease with signs of hypertension, edema, and protein urine due to pregnancy. In Indonesia preeclampsia is still one of the cause of maternal death, range 1,5 % - 2,5 %. The purpose of this study is to determine the relationship between maternal disease and a history of gravida with severe preeclampsia incidience in the General Hospital Center Dr. Mohammad Hoesin Palembang in 2012. The method used in this reserch is Analytical research with Cross Sectional Design. The Population in this research is a case of delivering mothers with severe preeclampsia and control mothers with lower preeclampsia. The number of samples is 242 maternal, 181 maternal with weight preeclampsia and 61 maternal with lower preeclampsia. The data analysis conducted univariate and bivariate statistics with Chi-Square test with significance level α = 0,05. For the univariate analysis of 242 maternal, 181 mothers ( 74,8 % ) with  severe preeclampsia.which belong to the category of mother with primigravida as much as 131 people ( 72,3 % ) and maternal with history of genetic maternal illnes of 90 people ( 49,7 % ) . while the results of the bivariate analysis, Chi-square statistical test showed that there was sifnificant association between gravida status with weight preeclampsia accident where ( p value = 0,008 ) and also significant relationship between history of genetic maternal illnes with weight preeclampsia accident where ( p value = 0,012 ). We hope this research can be turn of weight preeclampsia accident Suggestion with prevention, early diagnose and prompt treatment with Antenatal Care Consistenly.   ABSTRAK  Preeklampsia adalah penyakit dengan tanda-tanda hipertensi, edema, dan protein urine akibat kehamilan. Diindonesia preeklampsia berat masih merupakan salah satu penyebab kematian ibu berkisar antara 1,5% - 2,5 %.. Tujuan penelitian ini adalah untuk mengetahui hubungan antara status gravida dan riwayat penyakit genetik pada ibu hamil dengan kejadian preeklampsia berat di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2012. Metode yang digunakan dalam penelitian ini adalah Survei Analitik dengan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah kasus ibu hamil dengan preeklampsia berat dan kontrol yaitu ibu hamil dengan preeklampsia ringan. Jumlah sampel yang diperoleh sebanyak 242 ibu hamil, terdapat 181 ibu yang menderita Preeklampsia berat dan 61 ibu menderita preeklampsia ringan. Analisa data dilakukan secara univariat dan bivariat dengan uji statistik Chi-Square melalui tingkat kemaknaan α = 0,05. Untuk hasil analisa univariat dari 242 ibu hamil, 181 ibu ( 74,8 % ) menderita preeklampsia berat. Yang termasuk kategori ibu dengan primigravida sebanyak 131 orang ( 72,3 % ) dan ibu yang mempunyai riwayat penyakit genetik sebanyak 90 orang ( 49,7 % ). Sedangkan hasil dari analisa bivariat, uji statistik Chi-Square menunjukan bahwa ada hubungan yang bermakna antara status gravida dan kejadian preeklampsia berat dimana ( p value = 0,008 ) dan ada hubungan yang bermakna antara riwayat penyakit genetik dengan kejadian preeklampsia berat dimana ( p value = 0,012 ). Hasil penelitian ini diharapkan dapat menurunkan angka kejadian preeklampsia berat tentunya dengan melakukan pencegahan dan deteksi dini melalui pemeriksaan secara  teratur.  


Author(s):  
Risma N. Sulham

Objectives: To compare the expression of tenascin in the anterior vaginal wall in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Method: This study was a cross sectional study. The study was conducted in RS Dr. Wahidin Sudirohusodo and other network hospitals of Obstetrics and Gynecology Department of Hasanuddin University, Makassar, from 1st January 2011 to 1st April 2012. This study assessed the expression of tenascin in 35 women with pelvic organ prolapse grade III and IV and the controls were 35 women without pelvic organ prolapse. Tenascin expression was assessed by immunohistochemical examination using tenascin antibody staining (mouse monoclonal antibody Novacastratenascin C, code NCLTenasC). Sampling was done by consecutive sampling. Data processed by the chi-square. The significance level used was 0.05. Result: The result of this research shows that with exception of history of bearing baby > 4000 gr weight (p=0.572); age, parity, menopausal status, and body mass index were significantly different between the group. This indicates that the variable does not affect the calculation of research data. While parity, menopausal status and body mass index (BMI), from an analysis of risk factors for POP were associated with increased intensity of tenascin is significant in postmenopausal status, and BMI > 25 (overweight) (p


2020 ◽  
Vol 11 (4) ◽  
pp. 402-412
Author(s):  
Doha Abo Aljadayel ◽  
Hadi Jalilvand ◽  
Mojtaba Abdi ◽  
Hesam Jahandideh

Background and Objectives: Smell disorder such as dostorted olfaction (parosmia) is one of the most common symptoms of COVID-19. Therefore, this study aimed to investigate the improvement of symptoms of parosmia in patients with COVID-19 in 2020. Material and Methods: This cross-sectional study was conducted in summer and spring of 2020 using a data collection form which was validated with Cronbach's alpha of r=0.826. The study was done in an international health center in Tehran. To report descriptive results, mean, standard deviation, absolute frequency and absolute frequency percentage, and for analysis, independent t-test and chi-square test were used using SPSS software version 16 and the significance level was considered to be 0.05. Results: In total ,350 patients participated in the study, the prevalence of parosmia in patients was 15.14% and the mean and age deviation of patients was 32.71 ± 10.93 years. There was not a significant relationship between parosmia and gender (p value=0.317), age (p value=0.271), previous history of allergic symptoms (p value=0.083), family history of the disease (p value=0.638), taste disorder (p-value=0.768), and smoking (p-value=0.558). 31 cases (58.49 % of Patients) with parosmia had complete remission within 4-6 weeks. Conclusion: Due to the high prevalence of olfactory disorders, especially parosmia in patients with COVID-19, parosmia and other olfactory disorders can be used to screen and triage patients with COVID-19, especially moderate and mild patients. Patients with parosmia should be followed for at least 4 to 6 weeks and if they do not recover for up to 12 weeks, they should be referred to ENT specialists for more specific measures.


2021 ◽  
Vol 3 (2) ◽  
pp. 95-106
Author(s):  
Hariza Adnani ◽  
Indah Sovi Savitri

Previous research found that 4.17% of children under five who experienced poor nutritional status based on body weight in Klepu Village, Krangan District, Tumangung Regency. The purpose of this study was to determine the factors related to the nutritional status of children under five in Klepu Village, Kranggan District, Temanggung Regency. This observational survey research used a cross sectional study approach. The population consisted of 72 children under five, all of them were research subjects. The data was processed using the chi square test. It was concluded that the factors related to nutritional status were infectious conditions, history of exclusive breastfeeding, history of complementary feeding and income level of parents. Meanwhile, factors that are not related to nutritional status are maternal nutritional knowledge, energy nutrition level and protein consumption level.


Author(s):  
Wahyu Ida Muliana Wahyu Ida Muliana

ABSTRACT [Preeclampsia is a disease with signs of hypertension, edema, and protein urine due to pregnancy. In Indonesia preeclampsia is still one of the cause of maternal death, range 1,5 % - 2,5 %. Until recently, the cause of severe preeclampsia is unknown. Some risk factors include severe preeclampsia parity, age mother, gravida status, history of preeclampsia in the family, history of Genetic maternal illness and others. The purpose of this study is to determine the relationship between parity and age maternal disease weight preecklampsia mother with genesis in the General Hospital Center Dr. Mohammad Hoesin Palembang in 2012. The method used in this reserch is Analytical research with Cross Sectional Design. The Population in this research is a all maternal three semester. The number of samples is 157 maternal, 90 maternal with weight preeclampsia and 67 maternal that happen’t weight preeclampsia . The data analysis conducted univariate and bivariate statistics with Chi-Square test with significance level α = 0,05. For the univariate analysis of 157 maternal, 90 maternal (57,3%) with weight preeclampsia. Which belong to the category of mother with high resico parity as 60 maternal (38,2%), and mother with low resico parity as 97 maternal (61,8%). Mother with high resico age  as 84 maternal (53,5%), and mother with low age as 73 maternal (46,5%) . While the results of the bivariate analysis, Chi-square statistical test showed that there was sifnificant association between parity with weight preeclampsia accident where (p value=0,007) and also significant relationship between    age   maternal   with    weight      preeclampsia    accident      where. (p value = 0,000). We hope this research can be turn of weight preeclampsia accident Suggestion with prevention, early diagnose and prompt treatment with Antenatal Care Consistenly.     ABSTRAK Preeklampsia adalah penyakit dengan tanda-tanda hipertensi, edema, dan protein urine akibat kehamilan. Di Indonesia preeklampsia berat masih merupakan salah satu penyebab kematian ibu berkisar antara 1,5% - 2,5 %. Sampai saat ini penyebab terjadinya preeklampsia berat belum diketahui, beberapa faktor resiko terjadinya preeklampsia berat antara lain paritas, usia ibu, status gravida, riwayat preeklampsi dalam keluarga, riwayat penyakit genetik ibu, dsb. Tujuan penelitian ini adalah untuk mengetahui hubungan antara paritas dan usia ibu hamil dengan kejadian preeklampsia berat pada ibu hamil di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2012. Metode yang digunakan dalam penelitian ini adalah Survei Analitik dengan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah seluruh ibu hamil trimester III yang pernah di rawat di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang. Jumlah sampel yang diperoleh sebanyak 157 ibu hamil, terdapat 90 ibu hamil yang mengalami preeklampsia berat dan 67 ibu hamil yang tidak mengalami preeklampsia berat. Analisa data dilakukan secara univariat dan bivariat dengan uji statistik Chi-Square melalui tingkat kemaknaan α = 0,05. Untuk hasil analisa univariat dari 157 ibu hamil, 90 ibu hamil (57,3%) menderita preeklampsia berat. Yang termasuk kategori ibu dengan paritas resiko tinggi sebanyak 60 ibu hamil (38,2%), dan ibu dengan paritas resiko rendah sebanyak 97 ibu hamil (61,8%). Ibu yang mempunyai usia resiko tinggi sebanyak 84 ibu hamil (53,5%), dan ibu yang mempunyai usia resiko rendah sebanyak 73 (46,5%). Sedangkan hasil dari analisa bivariat, uji statistik Chi-Square menunjukan bahwa ada hubungan yang bermakna antara paritas dan kejadian preeklampsia berat dimana (p value = 0,007) dan ada hubungan yang bermakna antara usia ibu hamil dengan kejadian preeklampsia berat dimana (p value = 0,000). Hasil penelitian ini diharapkan dapat menurunkan angka kejadian preeklampsia berat tentunya dengan melakukan pencegahan dan deteksi dini melalui pemeriksaan secara  teratur.    


2019 ◽  
Vol 5 (4) ◽  
pp. 116-121
Author(s):  
Dina Lusiana Setyowati ◽  
Risva Risva ◽  
Andi Anwar ◽  
Nurul Afiah

Background: Occupational skin diseases are the most common occupational diseases in many countries. Dermatitis has become one of the top 10 occupational diseases (PAK) based on the potential incidence, severity, and prevention ability. Fishermen are one of the oldest occupations and have a high risk of occupational accidents or occupational diseases, which one of the risks is dermatitis due to the exposure to sea water containing salt which is high enough to absorb the water from the skin.Objective: This study aims to determine the incidence of dermatitis, working duration, duration of exposure, history of skin diseases, use of personal protective equipment, and personal hygiene in the fishing communities in North Bontang.Methods: This study is an analytic observational study with a cross sectional study design. The population in this study was the fishing community in Loktuan Urban-Village, North Bontang. The samples were taken with the purposive sampling and a sample of 154 fishermen was obtained. The data were collected with a questionnaire that has been tested for the validity. The statistical analysis was conducted by Chi Square test with a significance level of 0.05.Results: The results showed that the history of skin diseases, the duration of exposure are related to the incidence of dermatitis in fishermen.Conclusion: Further research is needed to find out other risk factors that can cause dermatitis in fishermen.


2018 ◽  
Vol 14 (2) ◽  
pp. 91
Author(s):  
Herli Gustiani

Abstract: Preeclampsia is a syndrome characterized by an increase in blood pressure and proteinuria that appears in the second trimester of pregnancy which is always recovered in the postnatal period. Preeclampsia can be influenced by many factors, but the analysis of risk factors for preeclampsia in Dr. Murjani Hospital has never been done, especially in relation to the pregnant women age, history of pregnancy, abortion, and stages of hypertension. Thus, this research needs to be done. This research was analytical study with cross sectional approach, which aims to explain the relationship between the age of pregnant women and the stages of hypertension with preeclampsia. Research subjects were patients who came to Dr. Murjani Hospital on 28 May-9 June 2018. Data were collected from the Medical Record section and analyzed by t-test to compare the average of two groups (normal and preeclampsia). Chi Square test with 95% confidence interval was used to find out the relationship between two variables. The results showed that there was no relationship between the age of pregnant mother with preeclampsia incident in Dr. Murjani Hospital, but the stages of hypertension is related with preeclampsia incident in Dr. Murjani Hospital. Keywords: preeclampsia, stage of hypertension, the age of pregnant women


Author(s):  
Sulistyowati Tuminah Darjoko ◽  
Woro Riyadina Djoeworo ◽  
Aprildah Nur Sapardin

Background<br />In Indonesia, the prevalence of injury has increased from 7.9% in 2007 to 8.2% in 2013. Among older persons, falls were the main cause of injury. The objective of this study was to determine the major risk factors and the magnitude of the risk for fall-related injury in older persons.<br /><br />Methods<br />A study of cross-sectional design was conducted on 4,222 respondents aged 60 years and over. Injury was defined as fall-related injury occurring in the previous 12 months that disturbed activity dailyu living (ADL). Data collection was done by: 1) interview about sociodemographics and health (including hearing impairment, non-communicable diseases and injury) using a questionnaire, 2) measurement of blood pressure and anthropometry (body mass index), 3) examination of vision in the right nd left eyes using tumbling E cards and pinhole eye covers. Data were analyzed using the chi square test and multiple logistic regression with 0.05 significance level.<br /><br />Results <br />After controlling for age, occupation, vision disorder, educational level and economic status, older women had a 2.0-fold increased risk for fall-related injury compared to men (aOR=2.30; 95% CI: 1.93-2.73; p=0.000); subjects with a history of stroke had a 2.0-fold increased risk for fall-related injury compared to those without a history of stroke (aOR=2.07; 95% CI: 1.38-3.09; p=0.000). Educational level was a confounding factor.<br /><br />Conclusion<br />Women and stroke sufferers were at higher risk of fall-related injury among older persons. Prevention of fall-related injury should be done by older persons through periodic control of their health condition.


Author(s):  
Desti Widya Astuti Desti Widya Astuti

ABSTRAK   Berdasarkan data di RSUD Kota Prabumulih bahwa terdapat peningkatan jumlah kejadian perdarahan post partum, tahun 2014 sebanyak 178 orang, tahun 2015 sebanyak 246 orang dan tahun 2016 sebanyak 151 orang. Penelitian ini bertujuan untuk mengetahui hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. Penelitian ini merupakan penelitian analitik dengan rancangan cross sectional. Populasi yang digunakan adalah semua ibu bersalin di RSUD Kota Prabumulih, sebanyak 1.296 ibu bersalin dan 306 sampel. Pengambilan sampel dengan mengunakan random sampling, analisa data menggunakan analisa univariat dan bivariat dengan menggunakan uji statistik chi-square dengan derajat kemaknaan 0,05. Hasil penelitian ini menunjukan bahwa dari 288 ibu bersalin terdapat 151 yang mengalami perdarahan post partum sebagian besar adalah ibu dengan umur resiko tinggi sebanyak 43 orang  (40,9%) dan ibu dengan jarak kehamilan resiko tinggi sebanyak 21 orang (17,3%). Hasil uju chi-square umur didapatkan p.value 0,000 < α 0,05 dan uji chi-square untuk jarak kehamilan didapatkan p.value 0,000 < α 0,05. Maka ada hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. ABSTRACK   Based on the data at District General Hospital (RSUD) Prabumulih, there was increasing of post-partum bleeding, in 2014, there were 178 people. In 2015, there were 246 people. And in 2016, there were 151 people. The purpose of the study was to know relationship between maternal mother and the distance and old post-partum bleedingat District General Hospital (RSUD) Prabumulih in 2013. The study was analytic researchwith cross sectional design. Population thas was used in the study was all maternal mother ar District General Hospital (RSUD) Prabumulih. It was about 1.296 maternal mother and from 306. Random sampilng was done in the study, data analyses used univariate and bivariate analyses by using chi-square statistic test with significance level 0,05. The study result showed that from 306 maternal mother, there were 151 mother who experienced old post-partum bleeding, the large of that was high maternal mother 43 people  (40,9%) and mother age high distance 21 people (17,3%). The result of chi-square test was p value 0,000 < α 0,05 and chi-square test for age was p value 0,000 < α 0,05. It meant that there was relationship between maternal mother and the distance and of post-partum bleeding at District General Hospital (RSUD) Prabumulih in 2016.


Author(s):  
Wulan Citra Sari, Ana Safitri Wulan Citra Sari, Ana Safitri

ABSTRAK   Pneumonia masih merupakan masalah kesehatan yang penting karena menyebabkan kematian bayi dan balita yang cukup tinggi yaitu kira-kira satu dari empat kematian yang terjadi. Tujuan penelitian ini adalah diketahuinya hubungan antara umur balita dan pengetahuan ibu dengan kejadian pneumonia pada balita di Puskesmas Cambai tahun 2016. Penelitian ini menggunakan metode Survey Analitik dengan pendekatan Cross Sectional. Populasi pada penelitian ini adalah semua ibu yang membawa atau memeriksakan balitanya yang umur < 5 tahun di Puskesmas Cambai tahun 2016, pada saat penelitian. Pengambilan sampel tersebut secara Non Random dengan teknik Accidental Sampling. Analisa data dilakukan secara univariat dan bivariat dengan uji statistik Chi-Square dengan tingkat kemaknaan α = 0,05. Hasil penelitian menunjukkan ada hubungan antara umur balita dan pengetahuan ibu dengan kejadian pneumonia pada balita di Puskesmas Cambai tahun 2016. Dari hasil penelitian ini, peneliti berharap petugas pelayanan kesehatan dapat meningkatkan pelayanan kesehatan bayi dan balita di Puskesmas Cambai , serta lebih sering melaksanakan penyuluhan tentang pneumonia dan penyuluhan mengenai makanan 4 sehat 5 sempurna, agar terciptanya balita sehat.     ABSTRACT Pneumonia is an important health problem because it causes the death of infants and toddlers are quite high, roughly one in four deaths. The purpose of this study is known huubungan between toddler age and maternal knowledge with pneumonia incidence in infants in health centers Cambai 2016. This study used a survey method with the Analytical cross-sectional approach. The population in this study were all mothers who carry their babies or check the age < 5 years at Health Center Cambai in 2016, at the time of the study. The sampling is non- random with accidental sampling technique. Data analysis was done using univariate and bivariate statistical test Chi - Square with significance level α = 0.05. The results of this study showed association between maternal age and knowledge toddlers with pneumonia incidence in infants in Health Center Cambai in 2016. From these results, researchers expect health care workers to improve health services in health centers babies and toddlers Cambai, and more frequently to conduct information about pneumonia and counseling about 4 healthy 5 perfect food , in order to create a healthy toddler.


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