scholarly journals Adiponection Serum Levels in Severe Preeclampsia

2021 ◽  
pp. 134-139
Author(s):  
Hermie M.M. Tendean ◽  
Juneke J. Kaeng ◽  
Astrina Supandy
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Pregnant Patient ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
Inform Consent ◽  
Cross Sectional ◽  
Research Procedure ◽  
The Difference

Objective : To determine the difference adiponectin serum levels in pregnant patient with severe preeclampsia and normotency in Manado. Methods : This study is a cross sectional study which the number of samples obtained was 52 samples in which the sample was divided into 26 pregnant samples with severe preeclampsia and 26 control samples. Samples were taken from Prof. dr. R. D. Kandou Manado Hospital and network hospitals around Manado within the inclusion and exclusion criteria. All patients were explained about the research procedure and singning the informed consent and take a blood sample by using the ELIZA method. After the data is collected, it is entered into the SPSS version 23.0 program for data analysis. Results : There was a significant relationship between adiponection serum levels with the incidency of severe preeclampsia and normotency. But for body mass index variables there were no significant differences by using T test (independent sample) in each severe preeclampsia and normotency pregnancy group where p=0.903. Body mass index, height, weight, and weight gain during pregnancy showed that there is no difference between cases and controls (p>0.05) which means that body mass index is not related to the stete of the severe preeclampsia and normotency. Conclusions : There was no relationship between BMI, age, parity, smoking, baby outcomes, delivery method and gestational age with the incidence of severe preeclampsia and normotency against adiponectin in this study. Keywords: adiponectin, obstetrics, preeclampsia.   Abstrak Tujuan : Untuk mengetahui perbedaan kadar adiponektin serum pada pasien hamil preeklamsia berat dengan hamil normal di Kota Manado. Metode : Studi ini merupakan studi potong lintang.  Jumlah Sampel yang didapatkan sebesar 52 sampel dimana sampel dibagi menjadi 26 sampel hamil dengan preeklamsia berat dan 26 sampel kontrol. Sampel diambil dari RSUP Prof. dr. R. D. Kandou Manado dan rumah sakit jejaring sekitar manado yang memenuhi kriteria inklusi dan eksklusi. Semua pasien dijelaskan mengenai prosedur penelitian dan penandatanganan inform consent baru dilakukan pengambilan sampel darah untuk dilakukan pemeriksaan laboratorium dengan menggunakan metode ELISA. Setelah data dikumpulkan, maka dimasukkan ke dalam program SPSS versi 23.0 untuk data analisis. Hasil : Perhitungan dengan menggunakan uji statistik Mann - Whitney menunjukkan bahwa terdapat perbedaan bermakna nilai rata-rata kadar adiponektin pada pasien hamil normal dengan pasien PEB     (p = 0,000). Adanya hubungan bermakna kadar adiponektin dengan kejadian preeklamsia berat. Namun untuk variabel IMT yang dilakukan secara uji t (sampel independen) didapatkan kesimpulan tidak terdapat perbedaan bermakna pada masing-masing kelompok normotensi dan kelompok preeklamsia berat di mana p= 0,903, indeks massa tubuh, tinggi badan, berat badan, serta pertambahan berat badan selama kehamilan tidak berbeda antara kasus dan kontrol (p>0,5). Ini berarti bahwa IMT tidak berhubungan dengan keadaan terjadinya preeklamsia berat. Kesimpulan: Tidak didapatkan hubungan antara IMT, usia, paritas, merokok, luaran bayi, cara persalinan dan usia kehamilan dengan kejadian preeklamsia berat dan normotensi  terhadap adiponektin pada penelitian ini. Kata kunci : adiponektin,  obstetri, preeklamsia.

scholarly journals Body Mass Index (BMI) and Dental Caries Experience among Children of Eastern Region of Nepal

2020 ◽  
Vol 1 (1) ◽  
pp. 4-7
Author(s):  
Tarakant Bhagat ◽  
Ashish Shrestha ◽  
Santosh Kumari Agrawal
Keyword(s):  
Body Mass Index ◽  
Dental Caries ◽  
Body Mass ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Caries Experience ◽  
Eastern Region ◽  
Anthropometric Measures ◽  
Cross Sectional ◽  
The Difference

 Introduction: Dental caries and obesity share some common, modifiable influences such as diet and lifestyle including changes in physical activity and food characters. So, obesity can be considered as a predictor of dental caries and various studies have shown the positive association between these two factors. Objective: The study aims to analyze the relationship between dental caries and BMI in children of eastern region of Nepal. Methods: A cross-sectional study design was used comprising 600 school children in eastern region of Nepal. Anthropometric measures for the calculation of Body Mass Index (BMI), occurrence of dental caries, missing, and filled teeth due to caries in both the primary and permanent dentition (dft and DMFT respectively) were collected. Data were analyzed using Spearman’s correlation and independent t test to assess correlation between dental caries and BMI. Results: Dental caries prevalence was 57.3%. The difference in caries experience among gender was insignificant (p = 0.172). Caries experience decreased significantly with increase in years of schooling (p = 0.002) and with increase in age (p < 0.001). Caries experience increased with an increase in BMI but was not significant (p = 0.199). There was a positive correlation between BMI and DMFT /DMFS but was not statistically significant. The correlation between dft and dfs was statistically significant. Conclusions: The study indicated that some form of correlation existed between BMI and dental caries but the association was weak. Healthy with age children experience more caries than overweight and underweight children.

scholarly journals The Study On Range Of Motion Of Hip And Knee In Prayer By Adult Muslim Males. A Preliminary Report

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ariff MS ◽  
Arshad AA ◽  
Johari MH ◽  
Rahimin Affandi MAS ◽  
Fadzli AS ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Range Of Motion ◽  
Body Mass ◽  
Preliminary Report ◽  
Weight Bearing ◽  
Negative Relationship ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Unit Increase ◽  
The Difference

Introduction: Praying represents a fundamental activity of daily living in Muslim community. Muslims need to adopt several postures that require deep flexion of the knee and hip to perform this daily obligation. This is a preliminary report of the study on hip and knee range of motion conducted to obtain normative passive and functional range of flexion data during Muslim prayers in both weight-bearing joints of normal Muslim adults. Methods: A cohort of Malay men aged between 20 to 30 years was recruited in this cross-sectional study. Passive range of motion and flexion angles of the joints in various postures during prayer were measured using a standard goniometer. The difference against existing normative range of motion database available and the influence of various factors were analysed. Factors analysed include body mass index and other anthropometric measurements. Results: Sixty participants recruited for the preliminary phase of this study. The mean (SD) of passive hip and knee flexions were higher compared to other existing normative range of motion database. A unit increase in body mass index will have 0.782 units lower of knee range of motion. The hip and knee flexion arc were from 74.1° to 119.0° and from 3.3° to 119.7° respectively. Conclusion: The range of motion involved for prayers was more for the knee but less for the hip as compared to the measured passive range of motion. Body mass index has a significant linear negative relationship with the passive range of motion of the knee, but not the hip.

scholarly journals Factors predicting serum clozapine levels in Middle Eastern patients

2022 ◽  
Author(s):  
Ahmed Hassab Errasoul ◽  
Mohammed A. Alarabi
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Smoking Status ◽  
Middle Eastern ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Therapeutic Drug ◽  
Clinical Predictors ◽  
Cross Sectional ◽  
Clozapine Dose

Objectives: Despite its superiority over other drugs for psychosis, clozapine remains underused and is associated with many clinical challenges, including difficulties in predicting serum levels. We thus investigated the clinical predictors of clozapine serum levels in Middle Eastern patients. Methods: This was a cross-sectional study including 94 patients of Middle Eastern ethnicity. Results: The average clozapine dose and serum level were 400 mg/daily and 705 ng/mL, respectively. Clozapine dose and serum levels were positively correlated (rs [94]=0.32, p=0.002). A predictive model of serum clozapine levels revealed that the daily dose, smoking status, use of fluvoxamine or lamotrigine, and body mass index predicted 43.6% of the variance in serum levels (p<0.001). Using this model, the maximum doses of clozapine to avoid levels above the optimal range (>650 ng/mL) were 300, 250, or 225 mg/day for non-smokers with a body mass index of 25, 30, or 35 kg/m2, respectively, and 475, 425, or 400 mg/day for smokers with a body mass index of 25, 30, or 35 kg/m2, respectively. Conclusions: These findings do not reduce the value of individualised therapeutic drug monitoring but may assist clinicians when prescribing clozapine to Middle Eastern patients. Further psychopharmacological studies are needed on this demographic population.

scholarly journals Prevalence of Thinness among Santal Preschool Children Using New Body Mass Index Cut-Off Points

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Subal Das ◽  
Kaushik Bose
Keyword(s):  
Body Mass Index ◽  
Preschool Children ◽  
Nutritional Status ◽  
Body Mass ◽  
Cross Sectional Study ◽  
High Rate ◽  
Tribal Community ◽  
Community Based ◽  
Cross Sectional ◽  
Purulia District

A community-based cross-sectional study was undertaken to determine the prevalence of undernutrition using body mass index (BMI) among 2–6-year Santal preschool children of Purulia District, West Bengal, India. A total of 251 (116 boys and 135 girls) children from 12 villages were measured. Commonly used indicators, that is, weight, height, and BMI, were used to evaluate the nutritional status. More boys (59.5%) than girls (53.3%), based on BMI, were undernourished. Significant age differences in weight (F=44.29∗∗∗; df=3), height (F=58.48∗∗∗; df=3), and BMI (F=3.52∗∗∗; df=3) among boys were observed. Similarly, significant differences between ages in mean weight (F=56.27∗∗∗; df=3), height (F=64.76∗∗∗; df=3), and BMI (F=2.62∗∗∗; df=3) were observed among the girls. The present study revealed that the nutritional status of the preschool children of Santal tribal community of these villages was poor with very high rate of thinness in boys and girls (59.5% and 53.3%, resp.).

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