scholarly journals A Simulation of a Novel High Quantum Efficiency Scintillating Fiber Detector with Anti-scatter Properties for Megavoltage X-Ray Imaging

2021 ◽  
Author(s):  
James Day
Keyword(s):  
Spatial Resolution ◽  
Detection Efficiency ◽  
Original Design ◽  
High Quantum Efficiency ◽  
Imaging Device ◽  
X Ray ◽  
Image Guided Radiation Therapy ◽  
X Ray Imaging ◽  
High Detection Efficiency ◽  
Square Array

To further develop a MV x-ray portal imaging device with high detection efficiency and adequate spatial resolution for image guided radiation therapy, the experimental results for a prototype detector were matched using Monte-Carlo software to then improve upon the design. The simulation and experiment were carried out using a 6 MV beam from a linear accelerator machine. An adequate match was obtained with the spatial resolution matching up to a MTF value of 0.2 and then diverging and the total signal registered in the central fiber was matched for field sizes ranging from 3 cm by 3 cm to 20 cm by 20 cm for 5 cm, 15 cm and 25 cm air gaps within 3%. The design was altered from a hexagonal array of round double cladded fibers to a square array of single cladded square fibers. The spatial resolution was improved from 0.242 lp mm-1 to 0.359 lp mm-1 at an MTF value of 0.5 from the original design to a square array of square fibers 0.5 mm wide separated by 0.25 mm of lead foil. With further optimization of the detector design it may be possible to increase spatial resolution for MV x-ray imaging while maintaining an adequate detection efficiency.

scholarly journals A Simulation of a Novel High Quantum Efficiency Scintillating Fiber Detector with Anti-scatter Properties for Megavoltage X-Ray Imaging

2021 ◽  
Author(s):  
James Day
Keyword(s):  
Spatial Resolution ◽  
Detection Efficiency ◽  
Original Design ◽  
High Quantum Efficiency ◽  
Imaging Device ◽  
X Ray ◽  
Image Guided Radiation Therapy ◽  
X Ray Imaging ◽  
High Detection Efficiency ◽  
Square Array

To further develop a MV x-ray portal imaging device with high detection efficiency and adequate spatial resolution for image guided radiation therapy, the experimental results for a prototype detector were matched using Monte-Carlo software to then improve upon the design. The simulation and experiment were carried out using a 6 MV beam from a linear accelerator machine. An adequate match was obtained with the spatial resolution matching up to a MTF value of 0.2 and then diverging and the total signal registered in the central fiber was matched for field sizes ranging from 3 cm by 3 cm to 20 cm by 20 cm for 5 cm, 15 cm and 25 cm air gaps within 3%. The design was altered from a hexagonal array of round double cladded fibers to a square array of single cladded square fibers. The spatial resolution was improved from 0.242 lp mm-1 to 0.359 lp mm-1 at an MTF value of 0.5 from the original design to a square array of square fibers 0.5 mm wide separated by 0.25 mm of lead foil. With further optimization of the detector design it may be possible to increase spatial resolution for MV x-ray imaging while maintaining an adequate detection efficiency.

scholarly journals Visualization Ability of Phase-Contrast Synchrotron-Based X-Ray Imaging Using an X-Ray Interferometer in Soft Tissue Tumors

2021 ◽  
Vol 20 ◽  
pp. 153303382110101
Author(s):  
Thet-Thet Lwin ◽  
Akio Yoneyama ◽  
Hiroko Maruyama ◽  
Tohoru Takeda
Keyword(s):  
Computed Tomography ◽  
Soft Tissue ◽  
Spatial Resolution ◽  
Phase Contrast ◽  
Soft Tissue Tumors ◽  
X Ray ◽  
3 Dimensional ◽  
Computed Tomography Images ◽  
X Ray Imaging ◽  
X Ray Computed

Phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer provides high sensitivity and high spatial resolution, and it has the ability to depict the fine morphological structures of biological soft tissues, including tumors. In this study, we quantitatively compared phase-contrast synchrotron-based X-ray computed tomography images and images of histopathological hematoxylin-eosin-stained sections of spontaneously occurring rat testicular tumors that contained different types of cells. The absolute densities measured on the phase-contrast synchrotron-based X-ray computed tomography images correlated well with the densities of the nuclear chromatin in the histological images, thereby demonstrating the ability of phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer to reliably identify the characteristics of cancer cells within solid soft tissue tumors. In addition, 3-dimensional synchrotron-based phase-contrast X-ray computed tomography enables screening for different structures within tumors, such as solid, cystic, and fibrous tissues, and blood clots, from any direction and with a spatial resolution down to 26 μm. Thus, phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer shows potential for being useful in preclinical cancer research by providing the ability to depict the characteristics of tumor cells and by offering 3-dimensional information capabilities.

scholarly journals ZnWO4 Nanoparticle Scintillators for High Resolution X-ray Imaging

Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1721
Author(s):  
Heon Yong Jeong ◽  
Hyung San Lim ◽  
Ju Hyuk Lee ◽  
Jun Heo ◽  
Hyun Nam Kim ◽  
...  
Keyword(s):  
Particle Size ◽  
Zinc Oxide ◽  
High Resolution ◽  
Tungsten Oxide ◽  
Spatial Resolution ◽  
High Spatial Resolution ◽  
X Ray ◽  
X Ray Imaging ◽  
Average Size ◽  
And Tungsten

The effect of scintillator particle size on high-resolution X-ray imaging was studied using zinc tungstate (ZnWO4) particles. The ZnWO4 particles were fabricated through a solid-state reaction between zinc oxide and tungsten oxide at various temperatures, producing particles with average sizes of 176.4 nm, 626.7 nm, and 2.127 μm; the zinc oxide and tungsten oxide were created using anodization. The spatial resolutions of high-resolution X-ray images, obtained from utilizing the fabricated particles, were determined: particles with the average size of 176.4 nm produced the highest spatial resolution. The results demonstrate that high spatial resolution can be obtained from ZnWO4 nanoparticle scintillators that minimize optical diffusion by having a particle size that is smaller than the emission wavelength.

Investigation of the luminescence, crystallographic and spatial resolution properties of LSO:Tb scintillating layers used for X-ray imaging applications

2014 ◽  
Vol 62 ◽  
pp. 28-34 ◽  
Author(s):  
A. Cecilia ◽  
V. Jary ◽  
M. Nikl ◽  
E. Mihokova ◽  
D. Hänschke ◽  
...  
Keyword(s):  
Spatial Resolution ◽  
X Ray ◽  
X Ray Imaging

APD-based x-ray imaging telescope using Fresnel zone plates for extremely high spatial resolution

2005 ◽  
Author(s):  
Michael R. Squillante ◽  
Richard A. Myers ◽  
Mitchell Woodring ◽  
James F. Christian ◽  
Frank Robertson ◽  
...  
Keyword(s):  
Spatial Resolution ◽  
High Spatial Resolution ◽  
Fresnel Zone ◽  
Fresnel Zone Plates ◽  
X Ray ◽  
Zone Plates ◽  
X Ray Imaging ◽  
Imaging Telescope

1D GaAs Detector Arrays for Digital X-ray Imaging with a 108- m Spatial Resolution

2004 ◽  
Vol 33 (4) ◽  
pp. 206-208
Author(s):  
V. F. Dvoryankin ◽  
Yu. M. Dikaev ◽  
A. I. Krikunov ◽  
T. M. Panova ◽  
A. A. Telegin
Keyword(s):  
Spatial Resolution ◽  
Detector Arrays ◽  
X Ray ◽  
X Ray Imaging

scholarly journals Megavoltage X-Ray Imaging Based on Cerenkov Effect: A New Application of Optical Fibres to Radiation Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
A. Teymurazyan ◽  
G. Pang
Keyword(s):  
Optical Fibres ◽  
X Rays ◽  
Modulation Transfer ◽  
Imaging Device ◽  
Active Matrix ◽  
X Ray ◽  
X Ray Imaging ◽  
Order Of Magnitude ◽  
Detection Quantum Efficiency ◽  
Cerenkov Effect

A Monte Carlo simulation was used to study imaging and dosimetric characteristics of a novel design of megavoltage (MV) X-ray detectors for radiotherapy applications. The new design uses Cerenkov effect to convert X-ray energy absorbed in optical fibres into light for MV X-ray imaging. The proposed detector consists of a matrix of optical fibres aligned with the incident X rays and coupled to an active matrix flat-panel imager (AMFPI) for image readout. Properties, such as modulation transfer function, detection quantum efficiency (DQE), and energy response of the detector, were investigated. It has been shown that the proposed detector can have a zero-frequency DQE more than an order of magnitude higher than that of current electronic portal imaging device (EPID) systems and yet a spatial resolution comparable to that of video-based EPIDs. The proposed detector is also less sensitive to scattered X rays from patients than current EPIDs.

scholarly journals Application of the Gatan X-ray Ultramicroscope (XuM) to the Investigation of Material and Biological Samples

2008 ◽  
Vol 16 (6) ◽  
pp. 14-17 ◽  
Author(s):  
Paul Mainwaring
Keyword(s):  
Sample Size ◽  
Spatial Resolution ◽  
Biological Samples ◽  
Easy Access ◽  
X Ray ◽  
Analytical Functions ◽  
Important Development ◽  
X Ray Imaging ◽  
Sem Imaging ◽  
Power Capability

X-ray ultramicroscopy in the SEM is a relatively new application in the wider field of X-ray microscopy. This latter field includes synchrotron and cabinet-based systems that vary in their X-ray power, capability, sample size, spatial resolution, and convenience. One important capability of the SEM-hosted X-ray microscope is that the normal SEM imaging and analytical functions such as secondary and backscattered imaging and microanalysis by EDX or WDS are unimpeded. X-ray imaging then serves as a complement to the normal use of the SEM. The convenience of easy access in an SEM lab to an X-ray microscope with 3D tomographic capability makes this an important development.

scholarly journals Potentialities of the future technical improvements in the search of rare nuclear decays by bolometers

2018 ◽  
Vol 33 (09) ◽  
pp. 1843003 ◽  
Author(s):  
Fabio Bellini
Keyword(s):  
Nuclear Physics ◽  
Detection Efficiency ◽  
Neutrinoless Double Beta Decay ◽  
Double Beta Decay ◽  
Particle Identification ◽  
X Ray ◽  
High Detection ◽  
High Detection Efficiency ◽  
Hybrid Devices ◽  
Excellent Energy Resolution

Bolometers are cryogenic calorimeters which feature excellent energy resolution, low energy threshold, high detection efficiency, flexibility in choice of materials, particle identification capability if operated as hybrid devices. After 30 years of rapid progresses, they represent nowadays a leading technology in several fields: particle and nuclear physics, X-ray astrophysics, cosmology. However, further and substantial developments are required to increase the sensitivity to the levels envisioned by future researches. A review of the challenges to be addressed and potentialities of bolometers in the search for rare nuclear decays is given, with particular emphasis to the neutrinoless double beta decay physics case.

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