scholarly journals Role Of Tea Tree Oil as A Skin Antimicrobial : A Literature Study

2021 ◽  
Vol 5 (1) ◽  
pp. 26-33
Author(s):  
Dian Ardiana
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Antiviral Activity ◽  
Skin Disease ◽  
Skin Diseases ◽  
Skin Infections ◽  
Tea Tree Oil ◽  
Literature Study ◽  
Tea Tree

Background: Skin disease due to microorganism infection are still widely found in community. The infections can be caused by bacteria, viruses, fungi, and parasite. Tea tree oil often used as a herbal medicine in the treatment of skin diseases due to microorganisms. This literature study is conducted to review the role of tea tree oil as an antimicrobial in skin infections. Method: Fifteen indexed journals published from 2015 to 2020 about tea tree oil and skin infections, were included. From 15 journals, 9 journals discuss antibacterial activity of tea tree oil, 2 journals discuss antiviral activity, 9 journals discuss antifungal activity, and 1 journal discusses antiparasitic activity. All journals state that tea tree oil has an antimicrobial effect on microorganisms that cause skin infections. Result: From 9 journals, it was found that A. baumanni, P. aeruginosa, and C. acnes were the most sensitive bacteria to tea tree oil in terms of MIC and S. epidermidis was the most sensitive bacteria, seen from their inhibition zone. Eight journals state variations with significant differences in the activity of tea tree oil as an anti-fungal. Tea tree oil has stronger antibacterial activity than antifungal activity. It also has antiviral activity against HSV and antiparasitic on S. scabiei. Conclusion: The conclusion of this study is that tea tree oil has antimicrobial activity against microorganisms that cause skin disease, including bacteria, viruses, fungi, and parasite.  

scholarly journals The Influence of Tea Tree Oil on Antifungal Activity and Pharmaceutical Characteristics of Pluronic®F-127 Gel Formulations with Ketoconazole

2021 ◽  
Vol 22 (21) ◽  
pp. 11326
Author(s):  
Magdalena Wróblewska ◽  
Emilia Szymańska ◽  
Katarzyna Winnicka
Keyword(s):  
Antifungal Activity ◽  
Fungal Infections ◽  
In Vitro Release ◽  
Antifungal Drugs ◽  
Artificial Skin ◽  
Diffusion Method ◽  
Skin Infections ◽  
Tea Tree Oil ◽  
Tea Tree ◽  
Gel Formulations

Fungal skin infections are currently a major clinical problem due to their increased occurrence and drug resistance. The treatment of fungal skin infections is based on monotherapy or polytherapy using the synergy of the therapeutic substances. Tea tree oil (TTO) may be a valuable addition to the traditional antifungal drugs due to its antifungal and anti-inflammatory activity. Ketoconazole (KTZ) is an imidazole antifungal agent commonly used as a treatment for dermatological fungal infections. The use of hydrogels and organogel-based formulations has been increasing for the past few years, due to the easy method of preparation and long-term stability of the product. Therefore, the purpose of this study was to design and characterize different types of Pluronic®F-127 gel formulations containing KTZ and TTO as local delivery systems that can be applied in cases of skin fungal infections. The influence of TTO addition on the textural, rheological, and bioadhesive properties of the designed formulations was examined. Moreover, the in vitro release of KTZ, its permeation through artificial skin, and antifungal activity by the agar diffusion method were performed. It was found that obtained gel formulations were non-Newtonian systems, showing a shear-thinning behaviour and thixotropic properties with adequate textural features such as hardness, compressibility, and adhesiveness. Furthermore, the designed preparations with TTO were characterized by beneficial bioadhesive properties. The presence of TTO improved the penetration and retention of KTZ through the artificial skin membrane and this effect was particularly visible in hydrogel formulation. The developed gels containing TTO can be considered as favourable formulations in terms of drug release and antifungal activity.

Role of tea tree oil in treatment of acne

2015 ◽  
Vol 28 (6) ◽  
pp. 404-404 ◽  
Author(s):  
Nooshin Bagherani ◽  
Bruce R. Smoller
Keyword(s):  
Tea Tree Oil ◽  
Tea Tree

scholarly journals A Comparative Clinical Study to Evaluate the Efficacy of Guduchyadi Kashaya and Rajrukshadipachana Kashaya in the Management of Eka Kushta w.s.r to Psoriasis

2021 ◽  
pp. 1-9
Author(s):  
Moulika Markonda ◽  
Sowmya S.B
Keyword(s):  
Clinical Study ◽  
Skin Disease ◽  
Skin Diseases ◽  
The Body ◽  
Skin Infections ◽  
Curative Effect ◽  
Causative Factors ◽  
Comparative Clinical Study ◽  
Modern Treatment ◽  
Chronic Course

In Ayurveda, all skin diseases have been described under the umbrella of Kushtha. Ekakusta is considered as the most commonest skin disease that can affect an individual. Acharya Charak has described the involvement of Vata-Kapha in Eka Kushtha. In the present study Eka kushtha is compared with psoriasis due to resemblance of signs symptoms and causative factors with it. Psoriasis is a papulosquamous disorder of the skin, characterized by sharply defined erythematosquamous lesions this illness exhibits a prompt response if treated carefully, left it may run a very chronic course extending into larger area of the body. Ayurveda focuses more on curative management than palliative management. The drug used in the treatment of Ayurveda does not have complications like modern treatment. Repeated Sodhana prevent the recurrence of the disease. Similarly various preparations have been advocated for the management of Psoriasis. The drugs used in this study are Guduchyadi Kashaya & Rajrukshadi Pachana Kashaya. Both the Kashayas are said to be effective in skin diseases. As per Yogaratnakara, Guduchyadhi Kwath has been mentioned as one of the drug having curative effect on all types of Kustha. Hence for present study the orally Guduchyadi Kwath is taken for EkaKustha treatment. The drugs in Guduchyadi Kwatha are Kusthaghana, Twachya, Swedal, Tridosh shamaka, as well as with Rasayan properties, which is beneficial to break down the pathogenesis of disease. As per Gadanigraha, as mentioned in Kayachikitsakhanda, Rajvrukshadipachana Kashaya is mentioned for the treatment of Ekakushtha. Ingredients in Rajvrukshadi Pachana Kashaya reduce Kapha dosha and most of them act on the skin. Kwatha dravyas are Rasadushtihara, Kaphapittahara, Deepana, Twachya, and also having antibacterial, antimicrobial, antiparasitic and anti-inflammatory properties, Hence, it is helpful for clearing the skin infections.

scholarly journals Synthesis and study of spectrally diagnosed heterocyclic compound

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2613-2622
Author(s):  
Sajida. Munadi. Th.AL-Suraify ◽  
Mohammed Abdul-Mounther Othman
Keyword(s):  
Antibacterial Activity ◽  
Mycobacterium Tuberculosis ◽  
Antifungal Activity ◽  
Heterocyclic Compounds ◽  
Antitubercular Activity ◽  
Pharmacological Activities ◽  
Mycobacterium Tuberculosis H37rv ◽  
Clinical Utilization ◽  
General Terms

In general terms, medicinal chemistry manages the revelation & plan of recent remedial synthetic concoctions & its uses as meds. Throughout the most recent couple of decades, mixes bearing heterocyclic cores have gotten considerably more consideration of the scientific expert, because of their expansive chemo remedial exercises, for example, calming, anthelmintic, hostile to tubercular, against parasitic & hostile to microbial exercises. Furthermore, Heterocycles & medicines are both interred related, the human is totally dependent on drugs & most of the drugs are derived from heterocyclic compounds. Hetero cycles & their derivatives have been excited regards chemist mainly due to broad-spectrum chemical & pharmacological activities. Most of the heterocyclic compounds are naturally occurs & playing the important role of metabolism regards cells of living. There has been a bigger count of pharmacologically attracted compounds of heterocyclic, several of which have been under continues clinical utilization. This paper presented a detailed study of synthesis which is spectrally detected Heterocyclic compounds, in results described the antibacterial activity of (e)-s-4-(is nicotinamide)-5-(phenoxymethyl)-4h-1, 2, 4-triazol-3-yl 3-(substituted phenyl) prop-2- enethioate. (7a-7f) and antifungal activity of (e)-s-4-(isonicotinamido)-5-(phenoxymethyl)-4h-1, 2, 4-triazol-3-yl 3-(substituted phenyl) prop-2-enethioate. (7a-7f), antitubercular activity of against mycobacterium tuberculosis h37rv presented the scope of this paper.

scholarly journals Effects of extraction solvent/technique on the antioxidant and antimicrobial activity of spring saffron (Crocus vernus (L.) Hill)

2020 ◽  
Vol 49 (2) ◽  
Author(s):  
Emir Horozić
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Skin Diseases ◽  
Ethanolic Extract ◽  
Early Spring ◽  
Aqueous Extracts ◽  
Bacterial Strains ◽  
Extraction Solvent ◽  
Ethanol Extracts

Spring saffron (lat. Crocus vernus (L.)Hill) is a perennial from the Iridaceae family. Purple or white coloured flowers bloom in the early spring. Saffron is commonly used in cookery, but because of its healing properties, crocus is also used in medicine for improving blood circulation, treating the cardiovascular diseases, preventing tumour and healing skin diseases. This research aimed to determine the influence of solvents (water, ethanol and acetone) on antioxidative, antimicrobial activity and the content of biologically important compounds, such as phenols and flavonoids in saffron. FRAP and DPPH methods were used to examine antioxidative activity. Antibacterial activity was analysed by using diffusion technique on bacterial strains of Escherichia coli, Enterococcus faecalis, Staphylococcus aureus, Bacillus subtilis, Listeria monocytogenes, and Pseudomonas aeruginosa. Antifungal activity was examined on Candida albicans. The results showed that the ethanol extracts have the highest antioxidant activity and the aqueous extracts have the lowest one. None of the tested extracts showed antibacterial activity, but aqueous extracts and ethanolic extract of saffron, obtained by maceration, showed antifungal activity.

Formulation and in vitro characterization of tea tree oil anti-dandruff shampoo

2021 ◽  
Vol 01 ◽  
Author(s):  
Humra Umar ◽  
Tariq Mahmood ◽  
Talib Hussain ◽  
Rabia Aslam ◽  
Yasser Shahzad ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Antifungal Activity ◽  
Synergistic Effects ◽  
Quality Attributes ◽  
Tea Tree Oil ◽  
Tea Tree ◽  
In Vitro Characterization ◽  
Selenium Sulfide

Background: Dandruff is the common scalp condition affecting half of the population of the world. Objective: The current study was aimed at developing anti-dandruff shampoos containing tea tree oil, which is believed to have effects against Malassezia furfur, a fungus involved in dandruff production. Methodology: Various shampoos containing tea tree oil in 0.5 to 3% concentration were prepared after careful selection of various shampoo ingredients. The formulated shampoos were subjected to various quality tests such as pH, viscosity, foam production, dirt dispersion, wetting time, surface tension, solid contents and antimicrobial activity against a model fungal strain, namely Candida albicans. The formulated shampoos were also compared with the marketed shampoos for quality attributes. Results: The results revealed that tea tree oil shampoos had pH values in the range of 5 – 6, which is close to the slightly acidic skin’s pH and considered as good for hair. All other quality attributes were comparable to the marketed products. The marketed shampoos had superior antifungal activity due to presence of zinc pyrithione or higher concentration of salicylic acid or selenium sulfide. Notwithstanding, the tea tree oil shampoos demonstrated an appreciable antifungal activity due to synergistic effects of tea tree oil, sodium lauryl sulphate and salicylic acid. Furthermore, the tea tree oil shampoos were stable during two months long stability testing. Conclusion: Thus, tea tree oil anti-dandruff shampoos have the potential to address the dandruff problem.

Antifungal activity of tea tree oil from Melaleuca alternifolia against Trichophyton equinum: An in vivo assay

Phytomedicine ◽  
2009 ◽  
Vol 16 (11) ◽  
pp. 1056-1058 ◽  
Author(s):  
F. Pisseri ◽  
A. Bertoli ◽  
S. Nardoni ◽  
L. Pinto ◽  
L. Pistelli ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Tea Tree Oil ◽  
Melaleuca Alternifolia ◽  
Tea Tree ◽  
In Vivo Assay

The Role of Psychological Stress in Skin Disease

2001 ◽  
Vol 5 (2) ◽  
pp. 140-145 ◽  
Author(s):  
Arash Kimyai-Asadi ◽  
Adil Usman
Keyword(s):  
Psychological Stress ◽  
Skin Disease ◽  
Basic Science ◽  
Skin Diseases ◽  
Case Reports ◽  
Numerous Case ◽  
Psychotherapeutic Interventions ◽  
Eczematous Dermatitis ◽  
Science Evidence

Background: Numerous case reports and studies have suggested that psychological stress may have a role in the onset or exacerbation of a variety of skin diseases. Objective: We review the literature pertaining to the role of psychological stress in the exacerbation of psoriasis, urticaria, eczematous dermatitis, herpesvirus infections, and other skin diseases; discuss potential mechanisms of stress-induced skin disease; and review studies and case reports of psychotherapeutic interventions that have been found helpful in the therapy of skin diseases. Conclusions: There is evidence linking psychological stress to exacerbation of certain skin diseases. Both the clinical and the basic science evidence, however, can be hard to interpret in light of the difficulty of defining and quantifying psychological stress as well as the questions regarding the etiologic significance of neuroimmunologic findings in skin diseases.

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