scholarly journals Portrait de Budé en «intellectuel»: la G. Budæi viri clarissimi Vita de Loys Le Roy (1540)

2000 ◽  
Vol 36 (4) ◽  
pp. 29-48
Author(s):  
Michel Magnien

Hellenist, philologist, historian, friend and counsellor to the King, mythical founding member of the Collège de France, as well as family man, Guillaume Budé appears to us as a hero of humanism and compels our collective admiration because he could lead simultaneously a contemplative and an active life. How was he perceived by his contemporaries? A few months after the death of the humanist (August 1540), while still in mourning, his disciple Loys Le Roy — a future bright light in the study of Greek — published the G. Budaei Vita. This biography is a virtual hagiography of a lay saint, endowed with a high mission, who sacrificed his health, even his life, to the cause of knowledge and the service of the King. This paper analyzes how a young humanist defines the role of humaniores litterae in an ordered society through their greatest incarnation.

2018 ◽  
Vol 15 (9) ◽  
pp. 877-882 ◽  
Author(s):  
Blanka Klimova ◽  
Kamil Kuca ◽  
Martin Valis ◽  
Jakub Hort

Background: Currently, there is a significant increase in the number of older generation groups, which may result in serious economic and social issues. Therefore, there is a need to prolong the active life of these older individuals, especially by focusing on modifying lifestyle factors such as healthy nutrition. In fact, recent research has shown that, for example, nuts are an important part of people’s healthy diet because they have appeared to be neuroprotective compounds which might maintain or in some cases even improve people’s cognitive functions. Objective: The purpose of this review study is to explore the role of the nut nutrition in the maintenance and delay of cognitive decline among older individuals. Results: The findings indicate that the nut consumption may contribute to the delay of cognitive decline in aging. However, this nut diet is just one component of the multi-nutrient dietary intervention for health aging. Conclusion: More longitudinal controlled randomized studies have to be performed in this field to prove the efficacy of the nut nutrition for the delay of cognitive decline.


Cephalalgia ◽  
2011 ◽  
Vol 31 (12) ◽  
pp. 1274-1281 ◽  
Author(s):  
Jakob Møller Hansen ◽  
Anne Werner Hauge ◽  
Messoud Ashina ◽  
Jes Olesen

Objective: The aim was to identify and describe migraine trigger factors in patients with familial hemiplegic migraine (FHM) from a population-based sample. Methods: 127 FHM patients were sent a questionnaire listing 16 trigger factors. Distinction was made between attacks of hemiplegic migraine (HM) and migraine with aura (MA) or without aura (MO) within each patient. Results: The response rate was 59% (75/127) of whom 57 (76%) had current HM attacks. Sixty-three per cent (47/75) reported at least one factor triggering HM, and 36% (27/75) reported at least one factor that often or always caused HM. Twenty per cent (15/75) reported only HM, whereas FHM in combinations with MA and MO were reported by 80% (60/75). Stress (with attacks either following or during the stress), bright light, intense emotional influences and sleeping too much or too little were the trigger factors mentioned by most. Conclusion: Many FHM patients report trigger factors and one-third reported at least one trigger factor often or always triggering FHM. The typical triggers are the same as for MA. Patients should be educated to avoid these factors. The role of trigger factors in the onset of new or first attacks of FHM remains unknown.


2019 ◽  
Vol 2 ◽  
pp. 56-62
Author(s):  
Marina Kolinko

The article presents the innovatory understanding of the nomadic strategy of human being in the transitional condition. The aim of the article is to determine the role of the nomadic being way in the social group of internal migrants. It is substantiated, that aims and actions of a nomad are directed on creating new ways of realization and conceptualization of variants of nomadic being. It is explained, that a nomad doesn’t go by the way, offered by traditional types of activity, but searches innovatory ways of realization, doesn’t stop on deciphering of traditionally existing being senses, but produces them him/herself. A subject, living in a space of “boundaries” is deprived of the settled comfort, he/she searches for a possibility of balance and harmony, social recognition and improvement of own life conditions in the movement and change. The culture of choice, formed by the logic of the modern market, gives a nomad resources for regulating the own freedom degree. Nomadic instruments correspond to the migrants’ way of life. Digital nomadism creates stimuli for the active life and adaptation to new conditions of different groups of migrants.


1970 ◽  
Vol 14 (2) ◽  
pp. 59-63
Author(s):  
Piotr Gleń
Keyword(s):  

The authors of this article present issues concerning not only disability but also rehabilitation, which allows the disabled to become more independent. The principal aim of this article is to discuss the problem of the handicapped who have to face the world that is still non-adapted to their needs in terms of architecture. Hence, this paper is focused particularly on the role of designers creating the space surrounding the disabled who strive for returning to normal active life.


Author(s):  
Peter Clegg ◽  
Derek O’Brien

The Turks and Caicos Islands, a British Overseas Territory, has witnessed a decade of constitutional and political upheaval; the consequences of which are still being felt. The locally elected government took advantage of its relative constitutional freedom to abuse its position and brought governance in the territory to almost beyond breaking point. The investigations that followed shone a bright light on how the local government operated, the checks and balances that were (or were not) in place, and the role of the British government, which is meant to uphold good governance in the territories. The chapter provides a detailed assessment of the constitutional, legal, and political issues and arguments that were used as the British government tried to correct the deep-seated structural weaknesses present in the TCI, and prosecute individual cases of venality that were uncovered. This case study is important in highlighting how tenuous constitutionality, democracy, and legality can be in small territories.


2000 ◽  
Vol 278 (1) ◽  
pp. R201-R208 ◽  
Author(s):  
M. M. Canal-Corretger ◽  
T. Cambras ◽  
J. Vilaplana ◽  
A. Díez-Noguera

To examine the role of light in the maturation of the circadian pacemaker, twelve groups of rats were raised in different conditions of exposure to constant bright light (LL) during lactation: both duration and timing of LL were varied. We studied the motor activity rhythm of the rats after weaning, first under LL and then under constant darkness (DD). In DD, two light pulses [at circadian time 15 (CT15) and CT22] were applied to test the response of the pacemaker. Greater exposure to LL days during lactation increased the number of rhythmic animals and the amplitude of their motor activity rhythm in the LL stage and decreased the phase delay due to the light pulse at CT15. The timing of LL during lactation affected these variables too. Because the response of the adult to light depended on both the number and timing of LL days during lactation, the exposure to light at early stages may influence the development of the circadian system by modifying it structurally or functionally.


2006 ◽  
Vol 128 (6) ◽  
pp. 671-685 ◽  
Author(s):  
Maureen E. Estevez ◽  
Petri Ala-Laurila ◽  
Rosalie K. Crouch ◽  
M. Carter Cornwall

Our ability to see in bright light depends critically on the rapid rate at which cone photoreceptors detect and adapt to changes in illumination. This is achieved, in part, by their rapid response termination. In this study, we investigate the hypothesis that this rapid termination of the response in red cones is dependent on interactions between the 9-methyl group of retinal and red cone opsin, which are required for timely metarhodopsin (Meta) II decay. We used single-cell electrical recordings of flash responses to assess the kinetics of response termination and to calculate guanylyl cyclase (GC) rates in salamander red cones containing native visual pigment as well as visual pigment regenerated with 11-cis 9-demethyl retinal, an analogue of retinal in which the 9-methyl group is missing. After exposure to bright light that photoactivated more than ∼0.2% of the pigment, red cones containing the analogue pigment had a slower recovery of both flash response amplitudes and GC rates (up to 10 times slower at high bleaches) than red cones containing 11-cis retinal. This finding is consistent with previously published biochemical data demonstrating that red cone opsin regenerated in vitro with 11-cis 9-demethyl retinal exhibited prolonged activation as a result of slowed Meta II decay. Our results suggest that two different mechanisms regulate the recovery of responsiveness in red cones after exposure to light. We propose a model in which the response recovery in red cones can be regulated (particularly at high light intensities) by the Meta II decay rate if that rate has been inhibited. In red cones, the interaction of the 9-methyl group of retinal with opsin promotes efficient Meta II decay and, thus, the rapid rate of recovery.


2017 ◽  
Vol 24 (1) ◽  
pp. 177-197 ◽  
Author(s):  
Alister Wedderburn

This article interrogates the role of tragedy within the work of International Relations theorists including Michael Dillon, Mervyn Frost, Richard Ned Lebow and Hans Morgenthau. It argues that a tragic sensibility is a constituent part of much thinking about politics and the international, and asks what the reasons for this preoccupation might be. Noting that a number of diverse theoretical appeals to tragedy in International Relations invoke analytically similar understandings of tragic-political subjectivity, the article problematises these by building on Michel Foucault’s intermittent concern with the genre in his Collège de France lecture series. It proposes that a genealogical consideration of tragedy enables an alertness to its political associations and implications that asks questions of the way in which it is commonly conceived within the discipline. The article concludes by suggesting that International Relations theorists seeking to invoke tragedy must think carefully about the ontological, epistemological, ethical and political claims associated with such a move.


2013 ◽  
Vol 8 (3) ◽  
pp. 351-359 ◽  
Author(s):  
Nicole Lovato ◽  
Leon Lack

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