scholarly journals Primitive Ocular Cancers in the University Hospital of Brazzaville

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Young Adults ◽  
Cell Carcinoma ◽  
Developed Countries ◽  
Sebaceous Carcinoma ◽  
Health Science ◽  
University Hospital ◽  
East African ◽  
Black Africa ◽  
Uveal Tract ◽  
The University

Introduction: With the exception of retinoblastoma and melanoma of the uveal tract, primitive ocular cancers originate from the accessory structures of the eye, especially the eyelids and the conjunctiva. While in developed countries these cancers are mostly encountered after 60 years, in black Africa their prevalence has increased in young adults. Objective: To determine the epidemiological, clinical and histological profile of these tumors in the University Hospital of Brazzaville. Methodology: Mini analysis of nine (9) of our publications, published between 2015 and 2017, in the journals: East African Medical Journal, Health Science and Diseases, EC Ophthalmology, and Revue de Médecine et de Pharmacie. HIV serology has been systematically requested except for cases of retinoblastoma. Histological evidence was made in all cases. Results: 86 patients had been seen. Average age 31.2 years (2 years - 75 years), sex ratio equal to 1.08. Reasons for consultation: exophthalmia (44), mass (35%), leucocoria (20%) and palpebral wounds (1%). Affected structures: conjunctiva (38%), retina (35%) and eyelid (27%). Histological types: squamous cell carcinoma (55.5%), retinoblastoma (25.9%), basal cell carcinoma (8.5%), sebaceous carcinoma (5.5%), Kaposia’s sarcoma (3.5%) and acral melanoma lentiginous (1.1%). HIV serology was positive in 38% overall, but in 100% of conjunctival cancers. Conclusion: Primitive ocular cancers are dominated in children by retinoblastoma. In young adults, these are essentially opportunistic cancers in the context of HIV / AIDS.

Family Background and Psychiatric Disorders

1973 ◽  
Vol 18 (3) ◽  
pp. 209-214 ◽  
Author(s):  
J. A. S. Marriott
Keyword(s):  
Cultural Differences ◽  
West Indies ◽  
Family Background ◽  
Developed Countries ◽  
University Hospital ◽  
Racial Groups ◽  
The West ◽  
Parental Absence ◽  
Psychiatric Units ◽  
The University

The admissions to the Psychiatric Unit of the University Hospital of the West Indies during a 15-month period from September 1966 to January 1968 have been reviewed with special reference to family background. Despite cultural differences the pattern of admissions was very similar to that of psychiatric units in more highly developed countries. The various racial groups in the island were represented and included a high proportion of white alcoholics. Parental absence in childhood was largely related to social class but there was a definite association between parental absence in childhood and psychologically precipitated depression.

scholarly journals Obesity in Pregnancy – Implications on Pregnancy Events

2020 ◽  
Vol 8 (B) ◽  
pp. 1157-1161
Author(s):  
Lilia Koleva ◽  
Victoria Spasova ◽  
Marieta Popova ◽  
Valentina Petkova ◽  
Milen Dimitrov
Keyword(s):  
Pregnant Women ◽  
Preterm Births ◽  
Developed Countries ◽  
Overweight And Obesity ◽  
University Hospital ◽  
Control Group ◽  
Case Group ◽  
Normal Limits ◽  
The University ◽  
Maternal Overweight

BACKGROUND: Overweight and obesity are serious health problems in most developed countries. The percentage of young women with excessive weight who get pregnant continues to grow every year. This raises a concern about the risks of the mother and the baby during pregnancy and after birth. AIM: This study aims to determine health risk for overweight mothers and especially the risk for preterm birth. MATERIALS AND METHODS: This is a prospective and retrospective study taking place in the outpatient clinic of the University Hospital “Maichin Dom”. Our study included 105 pregnant women with BMI ≥25 kg/m2 as a case group and 91 pregnant women with BMI within normal limits as a control group. RESULTS: Mean BMI in the case group was 34.79 ± 3.71 kg/m2 and 20.20 ± 2.24 kg/m2 in the control group. Among 105 women in the case group, we registered 24.8% (n = 26) who gave birth before term. Preterm births among 91 women in the control group were registered in 17.6% (n = 16) patients. We found a significant correlation between increased BMI and the risk of increased systolic and diastolic blood pressure. Moreover, we found comorbidities in 43.8% of cases and 24.2% of controls. CONCLUSION: Maternal overweight and obesity during pregnancy are associated with increased risks of preterm delivery and complications of pregnancy. Extra efforts should be made to help women lose weight before this important period of life.

scholarly journals Limberg flap as simplest solution for covering skin defects of different sizes and localizations

2020 ◽  
Vol 11 (2) ◽  
pp. 188-194
Author(s):  
Siniša Kojić ◽  
Zuhra Memić ◽  
Vera Sabljak ◽  
Helena Marić-Kujundžić ◽  
Bojan Kujundžić ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Late Complication ◽  
University Hospital ◽  
Limberg Flap ◽  
Lumbosacral Region ◽  
Transposition Flap ◽  
Basic Principles ◽  
The Face ◽  
Case Presentations ◽  
The University

Introduction. Whether it is a classic version of the flap or its modification, the Limberg flap is an appropriate solution for covering small and medium-sized defects, as well as for covering largesized defects where certain localizations are concerned. It represents a local, transposition flap that has proven to be a safe option. Methods. The defect coverage was achieved by marking a defect that was in the form of an equilateral rhombus by means of extending a shorter diagonal by the length of its side and drawing a parallel with the defect side, which created four different flaps. We included 50 patients surgically treated at the Varis Clinic for Plastic and Reconstructive Surgery in Belgrade and the University Hospital in Foca for the period 2018-2020. In all patients, we used the Limberg flap as a method for defect reconstruction. Case presentations. The sample was comprised of up to 50 patients, with an average respondent age of 60.3 years. According to etiology, the most common changes in the skin belonged to Basal cell carcinoma (58%), Squamous cell carcinoma (24%) and melanoma (8%), with the most common predilection sites associated with the face in 22 patients and with the lumbosacral region in 8 patients. A well-planned Limberg flap caused minor complications in terms of mild marginal infection in one patient, and mild marginal infection as an early complication and a stretched scar as a late complication in one patient as well. Other complications in the sample were not recorded. Conclusion. To obtain the best possible functional and esthetic result with minimal disruption of the region, respecting the anatomy and the basic principles in plastic surgery, the Limberg flap is an excellent solution for the reconstruction of defects of different sizes.

scholarly journals Metabolomic Profile of Young Adults Born Preterm

Metabolites ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 697
Author(s):  
Serafina Perrone ◽  
Simona Negro ◽  
Elisa Laschi ◽  
Marco Calderisi ◽  
Maurizio Giordano ◽  
...  
Keyword(s):  
Young Adults ◽  
Gestational Age ◽  
University Hospital ◽  
Metabolomic Profile ◽  
Risk Of Disease ◽  
Precise Moment ◽  
The University ◽  
Preterm Newborns ◽  
Insight Into ◽  
Control Study

Prematurity is a risk factor for the development of chronic adult diseases. Metabolomics can correlate the biochemical changes to a determined phenotype, obtaining real information about the state of health of a subject at that precise moment. Significative differences in the metabolomic profile of preterm newborns compared to those born at term have been already identified at birth. An observational case–control study was performed at the University Hospital of Siena. The aim was to evaluate and compare the metabolomic profiles of young adults born preterm to those born at term. Urinary samples were collected from 67 young adults (18–23 years old) born preterm (mean gestational age of 30 weeks, n = 49), and at term of pregnancy (mean gestational age of 38 weeks, n = 18). The urinary spectra of young adults born preterm was different from those born at term and resembled what was previously described at birth. The Random Forest algorithm gave the best classification (accuracy 82%) and indicated the following metabolites as responsible for the classification: citrate, CH2 creatinine, fumarate and hippurate. Urine spectra are promising tools for the early identification of neonates at risk of disease in adulthood and may provide insight into the pathogenesis and effects of fetal programming and infants’ outcomes.

A single institution retrospective analysis of basosquamous carcinoma of the head and neck

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 15530-15530 ◽  
Author(s):  
P. Clement ◽  
J. Verheezen ◽  
S. Nuyts ◽  
V. Vanderpoorten ◽  
R. Sciot
Keyword(s):  
Overall Survival ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Lymph Node Involvement ◽  
University Hospital ◽  
Base Of Tongue ◽  
Node Involvement ◽  
The University

15530 Background: Basosquamous Cell Carcinoma (BSCC) of the larynx, hypopharynx and base of tongue represents 1% of all head and neck tumours. It is considered a more aggressive disease than squamous cell carcinoma, based on higher incidence of advanced stage disease (60% lymph node-involvement and 40% metastases at diagnosis). Therefore, a treatment regimen including chemotherapy is often recommended in addition to surgery and/or radiotherapy in the literature. Methods: We retrospectively analyzed the data of all patients diagnosed with BSCC of the head and neck at the University Hospital of Leuven between 1993 and 2003, and report here the stage at diagnosis, treatment modality, disease evolution, progression free and overall survival. Results: Seven patients where diagnosed with BSCC in the head and neck region. Six patients were male. Three of the tumours were localised in the larynx, two at the base of tongue, and two in the oral cavity. The AJCC stages of disease ranged from I to IVa. Three patients had lymph node involvement at diagnosis. Six patients were treated with surgery in combination with radiotherapy. One patient was treated with cryotherapy before brachytherapy was applied. Five patients have no evidence of disease with a follow up of 4, 5, 6, 10 and 11 years, respectively. One patient died of an unknown cause 18 months after treatment. Only one of the seven patients, developed metastases during follow up. This patient had BSCC of the base of tongue, and was diagnosed with lungmetastases 16 months after surgery and radiotherapy. He was treated with the combination of Doxorubicine, Cisplatin and Fluorouracil. A partial response was confirmed after six cycles. Eight months after the last treatment cycle, there is still no evidence of disease progression. Conclusions: BSCC is a rare tumour of the head and neck. Seven patients were treated at the University hospital of Leuven in the period between 1993 and 2003 with a median progression free and overall survival of more than 5 years. Only one patient developed metastases, and was consequently treated with chemotherapy, inducing a continuing partial remission 8 months after treatment. In contrast to what is reported in the literature we do not confirm a high incidence of metastases at diagnosis nor a high mortality rate. No significant financial relationships to disclose.

Revolutionary versus Evolutionary Change: The Experience of a University Hospital Department of Psychiatry

1996 ◽  
Vol 9 (4) ◽  
pp. 53-55
Author(s):  
Marilyn Rook ◽  
Kenneth I. Shulman
Keyword(s):  
Change Process ◽  
Radical Change ◽  
Evolutionary Change ◽  
Health Science ◽  
University Hospital ◽  
Revolutionary Change ◽  
Hospital Department ◽  
University Of Toronto ◽  
Science Centre ◽  
The University

In the spring of 1991, the Department of Psychiatry at Sunnybrook Health Science Centre chose to undergo a major reorganization in an attempt to better meet the needs of patients as well as the academic and research requirements of the University of Toronto. This brief report describes the circumstances leading up to the decision to make a “revolutionary” change, the department's experiences during the period of radical change and the impacts of the change process.

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