scholarly journals Antimicrobial Resistance Pattern of Bacterial Isolates from Intensive Care Unit of a Tertiary Care Hospital in Bangladesh

2017 ◽  
Vol 8 (1) ◽  
pp. 7-11
Author(s):  
Taslima Akter ◽  
Mohammad Murshed ◽  
Taslima Begum ◽  
Kamrun Nahar ◽  
Syeda Sharmin Duza ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Tertiary Care ◽  
Resistance Pattern ◽  
Care Hospital ◽  
College Hospital ◽  
Antibiotic Susceptibility Pattern ◽  
Medical College ◽  
Highly Active ◽  
The Common

Infections with resistant strain are one of the leading causes of morbidity and mortality in hospitalized patients especially the critically ill patients in intensive care unit (ICU). The present study was conducted to know the changing pattern of antibiotic resistance of the common isolates from blood, urine, respiratory secretions and pus/ wound swab of patients admitted in ICU at Holy Family Red Crescent Medical College hospital over a two years period from January 2012 to December 2013. A total of 1282 samples were analyzed. Out of which 301 (23.5%) samples were positive for growth of organisms. The predominant isolates were E.coli (28%), Klebsiella (27%), Acinetobacter (17.3%), Pseudomonas (9.6%), Staphylococcus aureus (5.3%) & candida (6%). Majority isolates were resistant to Cephalosporin and Amoxycillin, (>70-90%). Carbapenem were still highly active against E.coli. However, Klebsiella, Pseudomonas and Acinetobacter were showing alarming resistance (55-60%) towards those drugs. Aminoglycosides resistance has also increased for Pseudomonas and Klebsiella. The percentage of Cloxacillin resistant for staphylococcus was near about 40%. The most active drug against Pseudomonas was piperacillin/Tazobactam. The positive result from this study was that organisms showed decreased resistance towards Tetracycline, Cotrimoxazole and Ciprofloxacin. The sensitivity of Nitrofurantoin for urinary isolates was good. Regular surveillance of antibiotic susceptibility pattern & judicious use of antibiotics is very important for reducing the infection rate and antimicrobial resistance.Bangladesh J Med Microbiol 2014; 08 (01): 07-11

scholarly journals Isolation of Acinetobacter species and their antimicrobial resistance pattern in a tertiary care hospital in Dhaka, Bangladesh

2017 ◽  
Vol 10 (1) ◽  
pp. 18-21
Author(s):  
Jannatul Ferdous ◽  
Mohammad Murshed ◽  
Sabeena Shahnaz ◽  
Syeda Sharmin Duza ◽  
Prothoma Rahman Siddique
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Control Strategies ◽  
Tertiary Care ◽  
Tracheal Aspirate ◽  
Resistance Pattern ◽  
Care Hospital ◽  
Acinetobacter Species ◽  
Medical College

Acinetobacter species are important opportunistic and nosocomial pathogens capable of causing both community and health careassociated infections (HAIs). The clinical specimens obtained from patients admitted in Holy Family Red Crescent Medical College and Hospital (HFRCMCH) from July 2013 to June 2015. All laboratory works were performed in department of microbiology and immunology of HFRCMCH. The infection rate was maximum in blood (67.7%) followed by urine (12.9%), tracheal aspirate (8.8%) and wound swab (3.32%). Most of the Acinetobacter were isolated from Intensive care unit (ICU) and Neonatal intensive care unit ( NICU). Acinetobacter displayed higher resistance to many antibiotics like Ampicillin which showed 96% resistance, Ceftriaxone 72%, Amikacin 72%, Imipenem 55%, Meropenem 60%, Tetraclycline 64%, Ciprofloxacin 60% and Cotrimoxazole showed 38% resistance. In conclusion, there was a high resistant rate to available and common antibiotics. It seems that infection control strategies may help to control the evolving problem of Acinetobacter infections and prevent an epidemic nosocomial life threatening infections.Bangladesh J Med Microbiol 2016; 10 (1): 18-21

scholarly journals Clinical and biochemical profile of neonatal seizures admitted in neonatal intensive care unit of a tertiary care hospital

2021 ◽  
Author(s):  
Mohanram V. ◽  
Arulraj Russelian ◽  
Palpandi V.
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Biochemical Profile ◽  
Neonatal Seizures ◽  
The Common

Background: Several factors contribute to seizures among neonates. To avoid complications from under recognition of clinical seizures and the adverse effects of medications administered, the diagnosis and management of neonatal seizures necessitate an interprofessional approach. Present study was done to study the clinical and biochemical profile of neonates with seizures admitted to a tertiary care hospital, Chennai.Methods: A cross sectional study was conducted where all the neonates from birth to 28 days of life who got admitted in the neonatal intensive care unit (NICU) of a tertiary care hospital-Shri Sathya Sai medical college and research institute were included in the study. Baseline characteristics of all the babies were noted on the prescribed proforma. Thorough physical examination was done and seizures were diagnosed by clinical observation. Clinical details of each seizure episode were recorded like age at onset of seizures, duration of seizure, number and type of seizure.Results: In the present study, 50 neonates satisfying the inclusion and exclusion criteria were included in the study. The main mode of delivery was normal vaginal delivery (50%) followed by LSCS (40%) and assisted delivery (10%). 54% were male and 46% were female and majority of babies were delivered at term i.e., 72% and 28% were pre term babies. The mean day of onset of seizures in the present study was 3.18±2.09. Based on day of onset of seizures, with in 24 hrs (28%), 24 hrs to 72 hrs (46%), 4th day to 1 week (22%), more than 1 week (4%). Based on type of seizure 64% had subtle type, 26% had tonic type and 10% had clonic type of seizures. In this study, 24% had hypoglycemia, and 10 (20%) had hypocalcemia, 14% in the present study had hyponatremia, and 2 (4%) had hypomagnesemia, 2 (4%) had hypernatremia, 6% had combination of hypocalcemia and hypoglycemia.Conclusions: Hypocalcemia, hypoglycemia, hyponatremia were the common biochemical abnormalities observed in our study. Subtle seizures were the common type of seizures observed among both pre term and term infants.

Pattern of Provoking Factors and Psychiatric Co- morbidity in Migraine Headache: A Study from Tertiary Care Hospital

2018 ◽  
Vol 16 (1) ◽  
pp. 7-10
Author(s):  
Tanveer Ahmed Khan
Keyword(s):  
Anxiety Disorder ◽  
Migraine Headache ◽  
Age Of Onset ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Co Morbidity ◽  
The Common ◽  
The Mean

Introduction: Headaches are the most prevalent neurological disorders and among the most frequent symptoms seen in general practice among which migraine only accounts up to 30%. Certain factors are found to play role in the triggering of migraine headache. Avoidance of such factors is part of migraine management. Psychiatric co morbidities are common in migraine. Recognizing these co morbidities could therefore result in improved patient management. Methods: This study was done at Nepalgunj medical college hospital, Nepalgunj. Duration of study was six months i.e. from 1st July 2017 to 31st December 2017. All the new cases fulfilling diagnostic criteria of migraine headache visiting to psychiatric outpatient department were included in this study. The diagnosis of migraine was made based on criteria mentioned by the international classification of headache disorders (ICHD-II). Result: A total of 50 patients were enrolled in this study. The mean age of participants was 28.60 ± 10.388 years. There was significant predominance of female participants. Family history of migraine was found in 20 (40%) of participants. The mean age of onset was 22.76± 7.899 years. The commonest type of migraine was migraine without aura in 2/3rd number of cases. Psychiatric co-morbidity was found in 26 (52%) subjects among which the most common co-morbidity was anxiety disorder in 16 (32%) followed by depression in 8 (16%). Presence of provoking factors was found in 38 (76%) subjects. Light, smoke, smell, noise and lack of adequate sleep were the common provoking factors. Conclusion: Migraine predominantly affects females with common age of onset in second and third decade. Psychiatric co-morbidities are common in migraine patients. Anxiety disorder and depression are the commonest co-morbidities. The common provoking factors are light, smoke, smell, noise and lack of adequate sleep found in migraine. Avoidance of provoking factors and early detection and management of psychiatric co morbidities can result in better outcome.

scholarly journals Pattern of Admission and Outcome in a Neonatal Intensive Care Unit (NICU) of a Tertiary Care Hospital in Dhaka, Bangladesh

2019 ◽  
Vol 10 (2) ◽  
pp. 150-158
Author(s):  
Gule Tajkia ◽  
Syed Khairul Amin ◽  
M Ekhlasur Rahman ◽  
Mumtahina Setu ◽  
Kuntal Roy ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Medical College ◽  
Disease Pattern

Background: The neonatal period is a highly vulnerable time for an infant completing many of the  physiologic adjustments required for life outside the uterus. As a result, there are high rates of morbidity  and mortality. To reduce morbidity and mortality it is essential to know the neonatal disease pattern.  Neonatal disease pattern changes from time to time and place. Analyzing the neonatal admission pattern  helps the policy makers to make the better strategies and health care givers to serve better. Objectives: This study aimed to determine the disease patterns and outcome of patients admitted to the  Neonatal Intensive Care Unit (NICU) of Anwer khan Modern Medical College Hospital, a tertiary care  hospital in Dhaka, between January 2017 to December 2018. Methods: Retrospective data from the medical records of all neonates admitted during the study period  were reviewed and analyzed for age, weight, sex, reason for admission, duration of hospital stay,  diagnosis and final outcome. Results: The total number of neonates admitted during the study period was 262; 164 were male (62.6%), and  98 were female (37.4%). A total of 223 patients (85.12%) wereborn in the hospital while 39 (12.88%) were  born at home. The majority were admitted during the first 48 hours of life (72.2%). A total of 5 patients (2%)  weighed <1000 gm; 53(20.2%) weighed 1000-1500 gm, and 89 (34%) between 1600-2499 gm. Prematurity  and infection were the main reasons for admission (52.7% and 20%, respectively), followed by birth asphyxia  (12%) and neonatal jaundice (6.8%). A total of 206 patients (78.6%) were improved and discharged, 43 left  against medical advice (16.4%), 3 were referred for urgent cardiac intervention (1.1%) and 10 (3.9%) died. Conclusion: Prematurity, neonatal infection and birth asphyxia were the major causes of neonatal  morbidity and mortality. Anwer Khan Modern Medical College Journal Vol. 10, No. 2: July 2019, P 150-158

scholarly journals Scenario of Sepsis in Intensive Care Unit in a Tertiary Care Hospital

2020 ◽  
Vol 18 (1) ◽  
pp. 99-102
Author(s):  
Ram Hari Ghimire ◽  
Sampanna Budhathoki ◽  
Rupesh Kumar Shreewastav
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Tertiary Care ◽  
Laboratory Data ◽  
Age Groups ◽  
Common Source ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Source Of Infection

Background: Sepsis has been defined as life-threatening organ dysfunction caused by dysregulated host response to infection. Sepsis is an important cause of mortality in intensive care unit worldwide. The study aims to identify the outcome of sepsis patient admitted at tertiary care hospital.Methods: This is a descriptive cross-sectional hospital based study on 76 adult patients admitted at intensive care unit of Nobel Medical College with diagnosis of sepsis with an objective of estimating mortality of sepsis and identifying associated symptoms with it. Baseline demographics, clinical and laboratory data were collected and analyzed. Results: Out of 76 patients with sepsis, mean age of the patients was 50.07±18.15 years. Majority of patients 31.6% with sepsis were above age groups >60 years. The most common symptoms among the patients were fever, which was seen in 69 (90.8%) patients. The most common source of infection in those patients was found to be unknown, which was seen in 36.8% of patients. While analyzing the outcome, it was noted that 25 patients with sepsis (32.9%) died during treatment.Conclusions: Sepsis is related with high mortality. Elderly patients are at more risk. Fever is the commonest presentation and source is not identified in majority of cases. Keywords: Intensive care unit; mortality; sepsis.

scholarly journals Microbial infection and antibiotic patterns among intensive care unit patients in a tertiary hospital in Central Nepal

2013 ◽  
Vol 8 (3) ◽  
pp. 1-8
Author(s):  
RK Sanjana ◽  
PC Majhi
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Antibiotic Susceptibility ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Microbial Infection ◽  
Laboratory Procedure ◽  
Antibiotic Susceptibility Pattern

Aims The present study is a fundamental effort to evaluate the bacteriological and antibiotic patterns in the Intensive Care Unit (ICU) setting in a tertiary care hospital. This study was carried out to guide the clinician in choosing the appropriate antibiotics and to prevent emergence of multidrug resistance bacteria. Materials and Methods Between March 2009 to Feb 2012, the samples from various ICUs that were submitted to the microbiology laboratory for culture and sensitivity were included in this study. All the organisms were identified morphologically and biochemically by standard laboratory procedure and antibiotic susceptibility pattern was determined by disc diffusion methods. Result Of 3,780 specimens, 2,312 (61.1%) isolates were recovered. Single organisms were isolated from 1,746 (75.5%) samples while the remaining 566 (24.4%) had two or more organisms isolated. Pseudomonas aeruginosa was the most common isolate 819 (35.4%), followed by Klebsiella pneumoniae 637 (27.5%). Antibiotics sensitivity of Pseudomonas aeruginosa showed that almost all isolates were resistant to cephalexin (97.8%) and ciprofloxacin (80.3%). However (95.8%) of the isolates were sensitive to tobramycin, (92.0%) to meropenem & (74.80 %) to amikacin. Conclusion It is concluded that Pseudomonas aeruginosa is the predominate pathogen isolated from ICUs of this Hospital. Most of the frequently isolated pathogens are resistant to cephalosporins and quinolone antibiotics as compared to aminoglycosides and carbapenem. Regular surveillance of antibiotic susceptibility pattern is very important for setting a guideline to the clinician in choosing an appropriate therapy of infected patients of ICUs. Journal of College of Medical Sciences-Nepal, 2012, Vol-8, No-3, 1-8 DOI: http://dx.doi.org/10.3126/jcmsn.v8i3.8678

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