scholarly journals Role of β-type natriuretic peptide as predictor of early post-operative outcomes in Chinese patients undergoing anesthesia

2017 ◽  
Vol 12 (4) ◽  
pp. 393
Author(s):  
Chun Chen ◽  
Lei Lin
Keyword(s):  
Hospital Stay ◽  
General Anesthesia ◽  
Natriuretic Peptide ◽  
Elective Surgery ◽  
Chinese Patients ◽  
Operative Outcomes ◽  
Study Results ◽  
Before And After ◽  
Prolonged Hospital ◽  
Relationship Of

<p class="Abstract">The purpose of the present study was to assess whether pre-operative and post-operative B-type natriuretic peptide (BNP) levels could be used as the predictor of post-operative complications in Chinese patients undergoing elective surgery under general anesthesia. A total of 80 adult patients were analyzed. Blood sample to measure BNP was collected from each patient before and after surgery to assess the relationship of pre-operative BNP with all possible clinical outcomes. Elevated BNP levels were associated with prolonged hospital stay and mortality. Our study results suggested that the high levels of BNP predict the prolong hospital stay, increased mortality, and increased usage of balloon pump. Also results suggested that the BNP is one of the key predictors of early post-operative outcomes in Chinese patients undergoing elective surgery under general anesthesia.</p>

scholarly journals Utilization of apnea-hypopnea index as a novel predictive factor for difficult mask ventilation in the Chinese population under general anesthesia

2020 ◽  
Author(s):  
Jia-Yi Wang ◽  
Jing-Jie Li ◽  
Peng-Cheng Zhao ◽  
Jia-Li Peng ◽  
Rong Hu ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Anesthesia ◽  
Elective Surgery ◽  
Chinese Patients ◽  
Apnea Hypopnea Index ◽  
Mask Ventilation ◽  
Clinical Trial Registry ◽  
Difficult Mask Ventilation ◽  
Physical Status Classification ◽  
Obstructive Sleep

Abstract Background: Difficult Mask Ventilation (DMV) is a potentially life-threatening situation that can arise during anesthesia. Accordingly, the majority of current airway management guidelines include risk assessments for DMV. Although Obstructive Sleep Apnea (OSA) is among the most important risk factors associated with DMV, other measurements such as the Apnea-Hypopnea Index (AHI) may play an important role in determining patient risk.This study investigated the relationship between DMV and AHI, and determined preoperative risk factors for DMV in Chinese patients.Methods: A prospective cohort trial enrolled patients scheduled for elective surgery. After obtaining informed consent, patient demographic information was collected, and patients were tested with pre-operative polysomnography. Inclusion criteria: Patients >18 years of age, American Society of Anesthesiologists Physical Status Classification (ASA) I-III, and planned elective surgery with general anesthesia. Exclusion criteria: malformations of the airway, patients undergoing regional anesthesia, and patients with contraindications to mask ventilation (i.e. planned awake intubation). A logistic regression model was used to analyze the association between AHI and DMV. Results: A total of 159 patients were analyzed. For both primary and secondary outcomes, the unadjusted and adjusted odds ratio for DMV showed significant increases of 5 AHI units. AHI, age, and the Mallampati classification were found to be independent predictive factors for DMV.Conclusions AHI is associated with DMV as a novel independent risk factor in Chinese patients. Along with age and Mallampati classification, AHI should be included in establishing a superior predictive strategy DMV screening.Trial registration: Chinese Clinical Trial Registry (Registration number # ChiCTR17013076; Date of Registration on October 22nd, 2017).

Outcomes After Receipt of Neuraxial or Regional Anesthesia Instead of General Anesthesia for Lower Limb Revascularization Surgery: Protocol for a Systematic Review and Meta-Analysis (Preprint)

2021 ◽  
Author(s):  
Derek Roberts ◽  
Hannah Dreksler ◽  
Sudhir K. Nagpal ◽  
Allen Li ◽  
Jeanna Parsons Leigh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Outcomes ◽  
Hospital Stay ◽  
General Anesthesia ◽  
Regional Anesthesia ◽  
Lower Limb ◽  
Meta Analysis ◽  
Study Results ◽  
Multicenter Randomized Controlled Trial ◽  
Revascularization Surgery

BACKGROUND Patients undergoing lower limb revascularization surgery for peripheral artery disease (PAD) have a high-risk of perioperative morbidity and mortality and often have long hospital stays. Use of neuraxial or regional anesthesia instead of general anesthesia may represent one approach to improving outcomes and reducing resource use among these patients. OBJECTIVE To conduct a systematic review and meta-analysis to determine whether receipt of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery for PAD results in improved health outcomes and costs and a shorter length of hospitalization. METHODS We will search electronic bibliographic databases (MEDLINE, EMBASE, and the seven databases in Evidence-Based Medicine Reviews), review articles identified during the search, and included article bibliographies. We will include randomized and non-randomized studies comparing use of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery for PAD. Two investigators will independently evaluate risk of bias. The primary outcome will be short-term mortality (in-hospital or 30-day). Secondary outcomes will include longer-term mortality; major adverse cardiovascular, pulmonary, and renal events; delirium; deep vein thrombosis or pulmonary embolism; major adverse limb events; neuraxial or regional anesthesia-related complications; graft-related outcomes; length of operation and hospital stay; costs; and patient-reported or functional outcomes. We will calculate summary odds ratios and standardized mean differences using random-effects models. Heterogeneity will be explored using stratified meta-analyses and meta-regression. We will assess for publication bias using Begg’s and Egger’s tests and use the trim-and-fill method to estimate the potential influence of this bias on summary estimates. Finally, we will use Grading of Recommendations, Assessment, Development, and Evaluation methodology to make an overall rating of the quality of evidence in our effect estimates. RESULTS The protocol was registered in PROSPERO, the international register of systematic reviews. CONCLUSIONS This study will synthesize existing evidence regarding whether receipt of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery for PAD results in improved health outcomes, graft patency, and costs, and a shorter length of hospital stay. Study results will be used to inform practice and future research, including creation of a pilot and then multicenter randomized controlled trial. CLINICALTRIAL PROSPERO CRD42021237060.

scholarly journals PENGARUH PEMBERIAN TERAPI MUSIK TERHADAP KECEMASAN PASIEN PRE GENERAL ANESTESI DI RS PKU MUHAMMADIYAH YOGYAKARTA

2018 ◽  
Vol 7 (2) ◽  
pp. 60-65
Author(s):  
Ichtiarfi Waryanuarita ◽  
Induniasih Induniasih ◽  
Yustiana Olfah
Keyword(s):  
Music Therapy ◽  
General Anesthesia ◽  
Elective Surgery ◽  
Intervention Group ◽  
Wilcoxon Test ◽  
Control Group ◽  
Dopamine Level ◽  
Before And After ◽  
Post Test ◽  
The Difference

Pre operative anxiety occur in patients that undergoing anesthesia procedure and elective surgery. Music therapy is one of distraction technique , because music can reduce physiological pain, stress, and anxiety. Music therapy pushed down sympathy nerve system that reduce body stress respons. Music cause the brain release endorphine, increase dopamine level, and help rise up safety feeling. Find out the effect of music therapy to anxiety in pre general anesthesia patients in PKU Muhammadiyah Yogyakarta Hospital. This study uses a quasy experimental which aims to see the difference in pre anesthesia anxiety before and after given music therapy in intervention and control group. This study uses quasy experimental design here takes group pre test and post test with control sort design. Patients is given pre test and post test with APAIS scale, in intervention group with treatment. Samples in this study amounted to 20 respondents of control group and 20 respondents of intervension group. Data collection is done on May to June 2017. The result of collected data were processed using Wilcoxon test with significant α = 0,05. There is a difference of anxiety before and after in the intervention group using music therapy. Wilcoxon test results obtained Sig. 0,000 (<0.05) so that H1 is accepted or rejected H0. There is a significant effect of music therapy to anxiety on pre general anesthesia patients in PKU Muhammadiyah Yogyakarta Hospital.

scholarly journals Incidence of hyponatremia and its utility as an indicator of morbidity in children hospitalised with community acquired pneumonia

2020 ◽  
Vol 7 (3) ◽  
pp. 616
Author(s):  
Thrilok Natarajan ◽  
Thahsheen Nilofar Sahubar Sadique ◽  
Kabilan Shanmugham
Keyword(s):  
Mechanical Ventilation ◽  
Hospital Stay ◽  
Severe Pneumonia ◽  
Hemodynamic Instability ◽  
Community Acquired Pneumonia ◽  
Prolonged Hospital Stay ◽  
Previously Treated ◽  
A Prospective Study ◽  
Prolonged Hospital ◽  
Relationship Of

Background: The aims of the study were to determine the incidence of hyponatremia associated with pneumonia and to assess its utility as an indicator of morbidity in children hospitalized with community acquired pneumonia between 2 months and 5 years of age.Methods: This was a prospective study of children aged 2 months to 5 years hospitalized with community acquired pneumonia. 120 children aged 2 months to 5 years with symptoms of lower respiratory tract infection and had radiological evidence of pneumonia were recruited into the study. Children with chronic diseases, previously treated with intravenous fluids and those with chronic drug intake were excluded from study.Results: Of the 120 children, 40.8% (49/120) had hyponatremia at admission. The relationship of hyponatremia to different clinical and laboratory parameters was analyzed. Sixty-one percent (31/51) of children under 1 year and 26% (18/69) of children between 1 to 5 years of age had hyponatremia (p=0.001). Hyponatremia was seen more commonly in children with severe pneumonia, with initial high temperature(p=0.001), with tachycardia (p=0.001), leukocytosis (p=0.001), increased neutrophils (p=0.001) and reactive thrombocytosis (p<0.001) and in children who had hemodynamic instability on admission (p<0.001). All 11(9.2%) children who required mechanical ventilation had hyponatremia (p<0.001). Consolidation was significantly associated with hyponatremia (p<0.001). Hyponatremia also showed a significant association with prolonged hospital stay (p<0.001).Conclusion: The incidence of hyponatremia in children hospitalised with pneumonia is 40.8%. This study concludes that the hyponatremia shows a significant association with the morbidity of the disease like requirement of intensive care and mechanical ventilation, hemodynamic instability and prolonged hospital stay. Hence the presence of hyponatremia at admission can be used as an indicator of morbidity.

scholarly journals Outcomes After Receipt of Neuraxial or Regional Anesthesia Instead of General Anesthesia for Lower Limb Revascularization Surgery: Protocol for a Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Derek J. Roberts ◽  
Hannah Dreksler ◽  
Sudhir K. Nagpal ◽  
Allen Li ◽  
Jeanna Parsons Leigh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Outcomes ◽  
Hospital Stay ◽  
General Anesthesia ◽  
Regional Anesthesia ◽  
Lower Limb ◽  
Meta Analysis ◽  
Study Results ◽  
Multicenter Randomized Controlled Trial ◽  
Revascularization Surgery

Abstract Background: Patients undergoing lower limb revascularization surgery have a high-risk of perioperative morbidity and mortality and often have long hospital stays. Use of neuraxial or regional anesthesia instead of general anesthesia may represent one approach to improving outcomes and reducing resource use among these patients. We propose to conduct a systematic review and meta-analysis to determine whether receipt of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery results in improved health outcomes and costs and a shorter length of hospitalization. Methods: We will search electronic bibliographic databases (MEDLINE, EMBASE, and the seven databases in Evidence-Based Medicine Reviews), review articles identified during the search, and included article bibliographies. We will include randomized and non-randomized studies comparing use of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery. Two investigators will independently evaluate risk of bias. The primary outcome will be short-term mortality (in-hospital or 30-day). Secondary outcomes will include longer-term mortality; major adverse cardiovascular, pulmonary, and renal events; delirium; deep vein thrombosis or pulmonary embolism; major adverse limb events; neuraxial or regional anesthesia-related complications; graft-related outcomes; length of operation and hospital stay; costs; and patient-reported or functional outcomes. We will calculate summary odds ratios and standardized mean differences using random-effects models. Heterogeneity will be explored using stratified meta-analyses and meta-regression. We will assess for publication bias using Begg’s and Egger’s tests and use the trim-and-fill method to estimate the potential influence of this bias on summary estimates. Finally, we will use Grading of Recommendations, Assessment, Development, and Evaluation methodology to make an overall rating of the quality of evidence in our effect estimates.Discussion: This study will synthesize existing evidence regarding whether receipt of neuraxial or regional anesthesia instead of general anesthesia in adults undergoing lower limb revascularization surgery results in improved health outcomes, graft patency, and costs, and a shorter length of hospital stay. Study results will be used to inform practice and future research, including creation of a pilot and then multicenter randomized controlled trial. Systematic Review Registration: Submitted to PROSPERO February 12, 2020.

scholarly journals Sleep/wake cycle of women submitted to elective gynecological surgery with a one-day hospital stay

2008 ◽  
Vol 16 (5) ◽  
pp. 838-843 ◽  
Author(s):  
Maria Cristina Zaros ◽  
Maria Filomena Ceolim
Keyword(s):  
Sleep Quality ◽  
Hospital Stay ◽  
Elective Surgery ◽  
Descriptive Study ◽  
Daily Routine ◽  
Matched Pairs ◽  
Gynecological Surgery ◽  
Day Hospital ◽  
Before And After ◽  
Total Data

The aim of this descriptive study was to compare preoperative and post-operative sleep/wake cycle (SWC) patterns of 22 women undergoing elective surgery, with up to one day of hospitalization. The study was approved by the local Review Board. Voluntary women (average age 39 ± 9) filled out a Sleep Journal for 23 consecutive days, before and after the surgery (46 days total). Data were analyzed with Wilcoxon's matched-pairs test. The findings showed slight and transitory SWC changes (increased latency, reduced efficiency and later wake-up time) after the surgery. Nevertheless, sleep quality was improved and there was a fast return to the SWC patterns observed before the intervention, perhaps due to the early exposition to daily routine, e.g. the environmental clues that are important to rhythmic synchronization.

scholarly journals Pancreas preservation time as a predictor of prolonged hospital stay after pancreas transplantation

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098705
Author(s):  
Shengmin Mei ◽  
Zhichao Huang ◽  
Yinlei Dong ◽  
Zheng Chen ◽  
Jie Xiang ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Pancreas Transplantation ◽  
Patient Survival ◽  
Length Of Hospital Stay ◽  
Prolonged Length ◽  
Pancreas Preservation ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Prolonged Hospital ◽  
Relationship Of

Objective Length of hospital stay is a sensitive indicator of short-term prognosis. In this retrospective study, we investigated how pancreas preservation time affects length of hospital stay after pancreas transplantation. Methods Patients receiving pancreas transplantation (1998.7–2018.6) were identified from the Scientific Registry of Transplant Recipients database and grouped according to pancreas preservation time. We analyzed the relationship of pancreas preservation time with graft and patient survival and prolonged length of stay (PLOS; i.e., hospital stay ≥20 days). Results We included 18,099 pancreas transplants in the survival analysis. Pancreas preservation time >20 hours had a significantly higher risk of graft failure than 8 to 12 hours. Pancreas preservation time was not significantly associated with patient survival. We included 17,567 pancreas transplants in the analysis for PLOS. Compared with 8 to 12 hours, pancreas preservation time >12 hours had a significantly higher PLOS risk, which increased with increased pancreas preservation time. In simultaneous pancreas–kidney transplantation, we also found that pancreas preservation time was positively associated with PLOS risk with pancreas preservation time >12 hours. Conclusion Pancreas preservation time is a sensitive predictor of PLOS. Transplant centers should minimize pancreas preservation time to optimize patient outcomes.

scholarly journals Impact Of Adopting IAS-IFRS On The Handling Of Accounting Data: The Case Of France

2014 ◽  
Vol 30 (4) ◽  
pp. 1239 ◽  
Author(s):  
Emna Boumediene ◽  
Salem Lotfi Boumediene ◽  
Olfa Nafti
Keyword(s):  
Earnings Management ◽  
Accounting Information ◽  
Discretionary Accruals ◽  
Accounting Data ◽  
Advantages And Disadvantages ◽  
Study Results ◽  
Accounting Numbers ◽  
Before And After ◽  
Relationship Of ◽  
The Impact

<p>In this article we look at the possible relation between the IAS-IFRS, which promotes a present value, and earnings management enhanced by the application of these standards. The aim of this paper is to analyse the impact of the adoption of IAS-IFRS standards on the earnings manipulation used by managers to manipulate their earnings and other accounting information in order to keep the same image in front of investors and shareholders.</p> <p>We are expanding, to the French context, the problem of information content of the discretionary component of accounting income in connection with the application of IAS-IFRS since 2005.</p> <p>On the basis of a sample of 96 firms-year observations, selected from France, that adopted the IAS-IFRS since 2005, we studied the relationship of association between accounting variables the impact of the use of IAS-IFRS on discretionary accruals. In other words, we tried to analyse the advantages and disadvantages of the adoption of IAS-IFRS.</p> <p>The study results show that the manipulation of accounting information existed both before and after the adoption of IAS-IFRS. However, the application of IAS-IFRS accounting standards in France had less motivated managers to manipulate the accounting numbers to increase earnings. Infact, the degree of earnings management is higher before the adoption of IAS-IFRS (the manipulations were 22.06% of discretionary accruals after adoption of IAS-IFRS and 31.28% before).</p>

THE CHILD'S LOSS OF CONSCIOUSNESS: A PSYCHIATRIC VIEW OF PEDIATRIC ANESTHESIA

PEDIATRICS ◽  
1972 ◽  
Vol 50 (2) ◽  
pp. 252-263
Author(s):  
Albert Bothe ◽  
Richard Galdston
Keyword(s):  
General Anesthesia ◽  
Psychological Stress ◽  
Ego Development ◽  
Pediatric Patients ◽  
Elective Surgery ◽  
Pediatric Anesthesia ◽  
Loss Of Consciousness ◽  
Frequency Of Occurrence ◽  
Anesthetic Induction ◽  
Before And After

Fifty healthy pediatric patients receiving general anesthesia for minor elective surgery were studied to assess how children experience and conceptualize induced unconsciousness. The techniques used by the patients and staff to minimize the psychological stress of anesthesia were observed. The findings confirm previous studies of the incidence of agitated behavior before and after anesthesia and suggest methods to decrease the frequency of occurrence. Behavioral signs predictive of agitation during anesthetic induction or emergence are discussed. The theoretical implications of these observations are related to ego development and to the capacity of the child to tolerate stress.

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