scholarly journals Alteration of haematolocial parameters of "zeol fish"- Clarias batrachus exposed to malathion

2013 ◽  
Vol 40 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Akhtarunnessa Chowdhury ◽  
Masudul Haq
Keyword(s):  
Active Ingredient ◽  
Tap Water ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Microcytic Anemia ◽  
Clarias Batrachus ◽  
Differential Count ◽  
Corpuscular Haemoglobin ◽  
Significant Difference ◽  
Mean Corpuscular Haemoglobin

Clarias batrachus, locally called zeol fish, reared in fresh water on protein diet were exposed to 5% (8.77 mg/l active ingredient) and 10% (17.74 mg/l active ingredient) concentrations of malathion at 24 h intervals, for three weeks in cement tanks containing 580 liters of water with a constant flow (1.5/1 min) of aerated dechlorinated tap water with no recirculation under natural light. Weekly two cc venous blood was drawn from each sample to determine the haematolocial parameters using EDTA (ethylenediamine tetraacetic acid) as an anticoagulant. The findings of this study showed that malathion in different concentrations have some diverse effects on the haematological parameters of Clarias batrachus. Exposer to 10% concentration of malathion was found to have a lethal effect on RBC, thrombocyte, neutrophil and Hb concentration which caused death of the fish with the sign of hypochromic microcytic anemia. Exposer to 5% concentration, on the other hand, showed leucopoenia due to decreased leucocyte counts. Haemoglobin (Hb) concentrations and values of mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV) and differential count of WBC levels showed decreased values at 5% concentration of malathion. Significant decrease (P<0.05) in Hb and concentration and MCH were observed during the exposer to the pesticide malathion. No significant difference (P>0.05) was observed in the levels of RBC, MCHC, PCV, MCV and WBC. DOI: http://dx.doi.org/10.3329/bjz.v40i2.14311 Bangladesh J. Zool. 40(2): 183-188, 2012

Titanium dioxide nanoparticles-induced cytogenotoxicity and alterations in haematological indices of Clarias gariepinus (Burchell, 1822)

2020 ◽  
Vol 36 (10) ◽  
pp. 807-815
Author(s):  
Opeoluwa M Ogunsuyi ◽  
Elizabeth O Adegoye ◽  
Olusegun I Ogunsuyi ◽  
Okunola A Alabi ◽  
Chibuisi G Alimba ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Tap Water ◽  
Clarias Gariepinus ◽  
Haemoglobin Concentration ◽  
Exposure Period ◽  
Negative Control ◽  
African Catfish ◽  
Mean Cell Volume ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin

The application of titanium dioxide (TiO2) nanoparticles (NPs) in the manufacturing of consumer products has increased tremendously and with the potential to induce deleterious effects on aquatic biota. There have been reports on metal oxide NP toxicity in aquatic organisms, however, information on cytotoxicity and genotoxicity of TiO2 NPs on the African catfish, Clarias gariepinus, is scarce. In this study, we investigated the genotoxicity and haematotoxicity of TiO2 NPs in C. gariepinus using the micronucleus (MN) assay and haematological analysis, respectively. Juvenile C. gariepinus were exposed to 6.25, 12.5, 25.0, 50.0 and 100.0 mg L−1 concentrations of TiO2 NPs for 7 and 28 days. Benzene (0.05 mL L−1) and dechlorinated tap water were used as positive and negative controls, respectively. Data of the MN showed a significant ( p < 0.05) concentration-dependent increase in the frequency of MN at both exposure periods in comparison to negative control. Red blood cells, haematocrit, platelets and heterophils significantly reduced with an increased mean corpuscular haemoglobin concentration and lymphocytes at the 7-day exposure period, while in the 28-day exposure period, mean cell volume, mean corpuscular haemoglobin and lymphocytes had a significant increase in comparison with the negative control. This study indicates that TiO2 NPs induced cytogenetic and haematological alterations in C. gariepinus and is of relevance in biodiversity and aquatic health management.

scholarly journals Haematology of air breathing mud eel, Monopterus cuchia (Hamilton, 1822) of Mymensingh and Kishoreganj districts of Bangladesh

2013 ◽  
Vol 22 (2) ◽  
pp. 127-134
Author(s):  
AFM Nazmus Salehin ◽  
Shankar Chandra Mandal
Keyword(s):  
Blood Cells ◽  
White Blood Cells ◽  
Haemoglobin Concentration ◽  
Air Breathing ◽  
Corpuscular Haemoglobin ◽  
Significant Difference ◽  
Haematological Profile ◽  
Mean Corpuscular Haemoglobin ◽  
Hb Concentration ◽  
Corpuscular Haemoglobin Concentration

Haematological profile of air breathing mud eel, Monopterus cuchia (Hamilton) from Mymensinghh and Kishoreganj were determined in the present study. Erythrocytes, lymphocytes, monocytes, neutrophils, eosinophils and platelet were evaluated. Significantly higher (p < 0.05) haemoglobin (Hb) concentration was found in air breathing mud eel of Kishoreganj than that of Mymensinghh area. The haematocrit (HCT), erythrocyte sedimentation rate (ESR), total red blood cells (TRBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), total white blood cells (TWBC), lymphocytes, neutrophils, monocytes, eosinophils did not show any significant difference. Findings of the present study showed little variation of haematological profile in air breathing mud eel sampled from Mymensinghh and Kishoreganj. Dhaka Univ. J. Biol. Sci. 22(2): 127-134, 2013 (July)

scholarly journals Haematological parameters of apparently healthy neonates at the Federal Medical Centre Bida, North Central Nigeria

2020 ◽  
Vol 6 (3) ◽  
pp. 276-286
Author(s):  
OE Ojewole ◽  
U Abubakar ◽  
AO Olowu
Keyword(s):  
Blood Cell ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Screening Tools ◽  
Haematological Parameters ◽  
Corpuscular Haemoglobin ◽  
Treatment Objective ◽  
Mean Corpuscular Haemoglobin ◽  
The Mean ◽  
Apparently Healthy

Background: Haematological parameters are used as screening tools for patient’s care and treatment. Objective: To determine the haematological parameters of apparently healthy term Nigerian babies and generate normative data. Methods: This was a descriptive, longitudinal study of consecutively recruited babies. The haematological parameters were determined using venous blood samples drawn at delivery and on the 14th day of life using a haematology auto-analyser. Results: Of the 309 babies recruited on the first day of life, 160 (51.8%) were males while 149 (48.2%) were females. Two hundred and seventy-nine (90.3%) were delivered vaginally.  Most (75%) of the neonates were of Nupe origin. The mean haematocrit, haemoglobin concentration, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), Mean Corpuscular Haemoglobin Concentration (MCHC), Red Blood Cell and reticulocyte count on Day 1 were 48.8±8.0%, 15.0±2.6g/dl, 104.1±8.8fl, 31.9±3.3pg, 30.7±1.7g/dl, 4.7±0.9 (×109/l) and 2.0±1.4% respectively. Corresponding Day 14 values were 41.2±5.2%, 12.8±1.9g/dl, 97.2±9.8fl, 30.3±3.8pg, 31.1±1.7g/dl, 4.5±0.6 (×109/l) and 1.0±0.7% respectively. The mean White Blood Cell (WBC) and platelet counts were 13.3±4.8 (×109/l) and 228.3±81.2 (×109/l) respectively, on the 1st day of life and 10.1±2.4 (×109/l) and 370.1±120.7 (×109/l) respectively on the 14th day. The mean differential WBC counts were 49.4±12.0% for neutrophils and 37.4±11.3% for lymphocytes on the 1st day and 32.4±10.0% and 52.8±9.3% respectively on the 14th day. Conclusion: Neonates from Bida have haematological parameters comparable with previously reported values from other parts of Nigeria.

scholarly journals Insecticide-treated net ownership, utilization and knowledge of malaria in children residing in Batoke–Limbe, Mount Cameroon area: effect on malariometric and haematological indices

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Rene Ning Teh ◽  
Irene Ule Ngole Sumbele ◽  
Derick Ndelle Meduke ◽  
Gillian Asoba Nkeudem ◽  
Samuel Takang Ojong ◽  
...  
Keyword(s):  
Blood Cell ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Full Blood Count ◽  
Haematological Parameter ◽  
Multilinear Regression ◽  
Corpuscular Haemoglobin ◽  
Mount Cameroon ◽  
Mean Corpuscular Haemoglobin ◽  
Haematological Indices

Abstract Background Insecticide-treated nets (ITNs) are the most widely used interventions for malaria control in Africa. The aim of this study was to assess the ownership and utilization of ITNs and the knowledge of malaria and their effects on malariometric and haematological indices in children living in the Mount Cameroon area. Methods A community-based cross-sectional study involving a total of 405 children aged between 6 months and 14 years living in Batoke–Limbe was carried out between July and October 2017. A semi-structured questionnaire was used to document demographic status, knowledge on malaria and ITN ownership and usage. Venous blood sample was collected from each child to determine the prevalence and intensity of parasitaemia by Giemsa-stained microscopy and full blood count by auto haematology analysis to obtain white blood cell (WBC) and red blood cell (RBC) counts, haemoglobin (Hb) level, haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). A multilinear regression model was used to determine the relationship between haematological parameter as dependent variable and the independent variables. Results The overall prevalence of parasitaemia, anaemia, knowledge about malaria, ITN ownership, usage and effective usage was 46.7%, 54.7%, 40.7%, 78.8%, 50.9% and 29.9%, respectively. The prevalence of parasitaemia was significantly higher (P < 0.001) in children who ineffectively utilized ITNs (54.9%) than effective users (27.3%). Having knowledge of malaria, negatively correlated with WBC counts (P = 0.005), but positively correlated with Hb levels (P < 0.001), RBC counts (P < 0.001), Hct (P < 0.001), MCV (P < 0.001) and MCH (P < 0.001). ITN use positively correlated with WBC counts (P = 0.005) but negatively with Hb levels (P = 0.004), RBC counts (P = 0.006), and MCH (P < 0.001). Meanwhile, parasitaemia negatively correlated with Hb levels (P = 0.004), RBC counts (P = 0.01), Hct (P = 0.04) and MCHC (P = 0.015). Conclusion There is need for more sensitization on the benefits of using the ITNs to meet up with the intended and expected impact of the free distribution of ITNs.

scholarly journals Insecticide Treated Net Ownership, Utilization and Knowledge of Malaria in Children Residing in Batoke-Limbe, Mount Cameroon Area: Effect on Malariometric and Haematological Indices

2020 ◽  
Author(s):  
Rene Ning Teh ◽  
Irene Ule Ngole Sumbele ◽  
Derick Ndelle Meduke ◽  
Gillian Asoba Nkeudem ◽  
Samuel Takang Ojong ◽  
...  
Keyword(s):  
Blood Cell ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Full Blood Count ◽  
Haematological Parameter ◽  
Malaria Parasitaemia ◽  
Corpuscular Haemoglobin ◽  
Mount Cameroon ◽  
Mean Corpuscular Haemoglobin ◽  
Haematological Indices

Abstract Background: Insecticide treated nets (ITNs) are the most widely used interventions for malaria control in Africa. The aim of this study was to assess the ownership and utilization of ITNs and the knowledge of malaria and their effects on malariometric and haematological indices in children living in the Mount Cameroon area.Methods: A community-based cross-sectional study involving a total of 405 children aged between 6 months and 14 years living in Batoke-Limbe was carried out between July and October 2017. A semi-structured questionnaire was used to document demographic status, knowledge on malaria and ITN ownership and usage. Venous blood sample was collected from each child to determine the prevalence and intensity of malaria parasitaemia by Giemsa-stained microscopy and full blood count by auto haematology analysis to obtain white blood cell (WBC) and red blood cell (RBC) counts, haemoglobin (Hb) level, haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). A multilinear regression model was used to determine the relationship between haematological parameter as dependent variable and the independent variables. Results: The overall prevalence of malaria parasitaemia (MP), anaemia, knowledge about malaria, ITN ownership, usage and effective usage was 46.7%, 54.7%, 40.7%, 78.8%, 50.9% and 29.9% respectively. The prevalence of MP was significantly higher (P<0.001) in children who ineffectively utilized ITNs (54.9%) than effective users (27.3%). Having knowledge of malaria, negatively correlated with WBC counts (P = 0.005) but positively correlated with Hb levels (P < 0.001), RBC counts (P < 0.001), Hct (P < 0.001), MCV (P < 0.001) and MCH (P < 0.001). ITN use positively correlated with WBC counts (P = 0.005) but negatively with Hb levels (P = 0.004), RBC counts (P = 0.006), and MCH (P < 0.001). Meanwhile, MP negatively correlated with Hb levels (P = 0.004), RBC counts (P = 0.01), Hct (P = 0.04) and MCHC (P = 0.015). Conclusion: There is need for more sensitization on the benefits of using the ITNs to meet up with the intended and expected impact of the free distribution of ITNs.

scholarly journals Effects of antioxidant supplementation on oxidative stress balance in young footballers- a randomized double-blind trial

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Błażej Stankiewicz ◽  
Mirosława Cieślicka ◽  
Sławomir Kujawski ◽  
Elżbieta Piskorska ◽  
Tomasz Kowalik ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Capacity ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Thiobarbituric Acid ◽  
Antioxidant Supplementation ◽  
Double Blind ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin ◽  
Chokeberry Juice

Abstract Background Intensive physical exercise that competitive sports athletes participate in can negatively affect their pro-oxidative–antioxidant balance. Compounds with high antioxidant potential, such as those present in chokeberry (Aronia melanocarpa), can prevent these adverse changes. We here investigated the effect of antioxidant supplementation on oxidative stress balance in young footballers. Methods The study was designed as a double-blind randomized trial. Diet of a group of young football players (male; n = 20; mean age, 15.8 years-old) was supplemented with 200 ml of chokeberry juice per day, for 7 weeks. The players were randomly assigned to the experimental (supplemented, FP-S; n = 12) and control (placebo, FB-C; n = 8) groups. Before and after the supplementation period, the participants performed a beep test. Venous blood was sampled for serum analysis before, immediately after, 3 h, and 24 h after the beep test. Serum levels of thiobarbituric acid reactive products, 8-hydroxy-2′-deoxyguanosine, total antioxidant capacity, iron, hepcidin, ferritin, myoglobin, and albumin, and morphological blood parameters (red blood cells, (RBC), haemoglobin (HGB), haematocrit (HCT) mean corpuscular volume (MCV) mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), and lactic acid) were determined. Results Chokeberry juice supplementation did not significantly affect the outcome of the beep test. The supplementation did not significantly affect any of the morphological, biochemical, or performance parameters analysed. Conclusions Chokeberry juice supplementation did not affect the measured parameters in the studied population, which may indicate insufficient antioxidant capacity of the juice.

scholarly journals Examination of Haematotoxicity of Fixed-Dose Highly Active Antiretroviral Drug in Albino Wistar Rats

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Thomas Nubila ◽  
Ernest O. Ukaejiofo ◽  
Nkoyo I. Nubila ◽  
Godfrey I. Okorie
Keyword(s):  
Highly Active Antiretroviral Therapy ◽  
Wistar Rats ◽  
Venous Blood ◽  
Haemoglobin Concentration ◽  
Test Group ◽  
Mean Value ◽  
Fixed Dose ◽  
Control Group ◽  
Highly Active ◽  
Significant Difference

Highly active antiretroviral therapy (HAART) is considered toxic and has other life-threatening side effects. Our aim was to evaluate the haematotoxic effects of lamivudine, zidovudine, and nevirapine fixed-dose combinations in Albino Wistar rats. Fifty (50) three (3) months old male Albino Wistar rats weighing between 200 and 250 g were randomly assigned to five (5) groups (A, B, C, D, and E). Group A served as control. Two (2 mLs) of venous blood was aseptically collected on Days 5, 10, 15, 20, and 25 of treatment. Red blood cell (RBC) mean value recorded statistically significant increase () in groups B and C when compared with the control group on Day 5. However, there was a statistically significant decrease () in RBC, haemoglobin concentration (Hb), packed cell volume (PCV), and some red cell indices on Day 10. In addition there was no statistically significant difference () in all the parameters evaluated when the test group was compared with the control on Day 25. Furthermore, there was a time-related statistically significant increase () in the two major blood cells—RBC and platelet counts. From the result of this present study, it can be concluded that HAART when administered in fixed-dose combinations have no subacute haematotoxic effects.

scholarly journals Nitrite Intoxication of Common Carp (Cyprinus carpio L.) at Different Water Temperatures

2006 ◽  
Vol 75 (4) ◽  
pp. 561-569 ◽  
Author(s):  
H. Kroupová ◽  
J. Máchová ◽  
V. Piačková ◽  
M. Flajšhans ◽  
Z. Svobodová ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Common Carp ◽  
Cyprinus Carpio ◽  
Haemoglobin Concentration ◽  
Nitrite Accumulation ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin ◽  
Higher Temperature ◽  
Lower Temperature ◽  
Plasma Nitrite

Common carp (Cyprinus carpio L.) were exposed to nitrite (1.45 mmol l-1 NO2-) for 48 hours at 14 °C and 20 °C, in order to investigate the mechanism of nitrite poisoning at these water temperatures. The effect of nitrite exposure on fish was assessed on selected haematological and biochemical indicators of the blood. Moreover, nitrite accumulation in the blood, liver and muscle was measured. Nitrite exposure produced high levels of methaemoglobin (88.2 ± 3.3% and 92.9 ± 6.1%) at both water temperatures compared with controls (0.3 ± 0.6% and 2.6 ± 3.0%). High fish mortality occurred in experimental groups (30% and 51%) compared with controls (0%). Nitrite exposure also resulted in an accumulation of nitrite in the fish body. The highest nitrite levels developed in the blood plasma, followed by the liver and muscle, respectively. Carp concentrated nitrite in the blood plasma and tissues to markedly higher levels at higher temperature (20 °C). The plasma nitrite concentrations (10.5 ± 1.9 mmol l-1) were in this case more than 7 times higher than the environmental one. At lower temperature (14 °C), plasma nitrite concentration reached 5.0 ± 1.5 mmol l-1. In either event, plasma K+ levels increased and Cl- levels and osmolality remained unchanged. Plasma Na+ levels slightly decreased at the higher temperature. Nitriteexposed fish showed lower haematocrit values (PCV) at both experimental temperatures compared with controls. At 20 °C, the blood haematocrit decrease (0.20 ± 0.02 l l-1) was accompanied by a low erythrocyte count (1.05 ± 0.12 1012 l-1) and by a low haemoglobin level (51 ± 11 g l-1). At the lower temperature (14 °C), the haematocrit decrease (0.25 ± 0.02 l l-1) was caused by a low mean corpuscular volume (167 ± 27 fl). No significant changes were observed in the mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), or selected erythrocyte dimensions (major axis, minor axis and aspect ratio).

scholarly journals Haematological and Serum Biochemical Profile of Growing Yankasa Ram Lambs Fed Diets Containing Graded Levels of Sesame Residue

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
Y. Garba ◽  
E. A. Adeola
Keyword(s):  
Blood Cells ◽  
Biochemical Parameters ◽  
White Blood Cells ◽  
Haemoglobin Concentration ◽  
Serum Biochemical Parameters ◽  
Corpuscular Haemoglobin ◽  
Randomized Design ◽  
Serum Biochemical ◽  
Mean Corpuscular Haemoglobin ◽  
Ram Lambs

An experiment was carried out to test the effect of Sesame residue (SR) inclusion in the diets of growing Yankasa ram lambs on haematological and serum biochemical parameters. Twelve (12) Yankasa ram lambs with initial body weight of 20.08±3.08kg were allotted to three dietary treatments containing 0, 20 and 30% SR (A, B and C). A completely randomized design was used for the study which lasted twelve (12) weeks. The haemetology results revealed that the white blood cells (12.85-16.85 109/L), red blood cells (1.49-2.04 1012/L), haemoglobin, mean corpuscular haemoglobin concentration (MCHC), mean corpuscular haemoglobin (MCH) (39.85-48.00 pg), mean corpuscular volume (MCV) and lymphocytes differed significantly (P<0.05) among the treatments. Lambs fed 30% SR had the highest MCV, MCH, MCHC and lymphocyte values. Serum biochemical analysis results revealed that lambs fed 20% and 30% SR had higher alkaline phosphatase, total protein and globulin values than lambs fed 0%SR. However, SR inclusion in the diets did not affect calcium and phosphorus levels of the lambs. In conclusion, including sesame residue at 30% in the diets of growing Yankasa ram lambs had no observable adverse effect on haematological and serum biochemical parameters.

Effects of Thyroid Function on Blood Cell Counts and Red Cell Indices – A Retrospective Study at a Tertiary Care Centre in Mandya, Karnataka

2021 ◽  
Vol 8 (27) ◽  
pp. 2434-2438
Author(s):  
Siddegowda M.S ◽  
Chaithra R ◽  
Shivakumar S ◽  
Maithri C.M
Keyword(s):  
Blood Cell ◽  
Blood Cells ◽  
Thyroid Dysfunction ◽  
Haematological Parameters ◽  
Red Cell ◽  
Corpuscular Haemoglobin ◽  
Significant Difference ◽  
Red Cell Indices ◽  
Mean Corpuscular Haemoglobin ◽  
Rbc Count

BACKGROUND Thyroid hormones play an important role in the regulation and production of red blood cells. Thyroid dysfunction induces different effects on blood cells such as anaemia, erythrocytosis, leucopenia, thrombocytopenia and alteration in red cell indices. In this study, we wanted to compare the changes in haematological parameters of thyroid dysfunction patients with those of euthyroid group. METHODS This was a retrospective study done on 310 individuals by collecting data from the medical records. Later the patients were categorized into hypothyroid (33) thyroid stimulating hormone (TSH > 5.5 μIU/mL), hyperthyroid (19) (TSH < 0.3 μIU/mL) and euthyroid (258) (TSH = 0.3 - 5.5 μIU/ml) groups. The haematological parameters of all these patients were obtained by 5-part automated cell count analyser. Finally, the obtained data was analyzed by statistical package for social sciences (SPSS) software. RESULTS The data obtained from the analysis revealed statistically significant (P < 0.05) difference between hypothyroidism, hyperthyroidism and euthyroidism in mean red blood cell (RBC) count, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), red cell distribution width (RDW), white blood cell (WBC) count and platelet count but the difference was not significant for mean haemoglobin, mean corpuscular haemoglobin concentration (MCHC) (P > 0.05). The mean haemoglobin was lower in hypothyroid patients when compared to euthyroid and hyperthyroid patients. The RBC count (P < 0.007), MCH (P = 0.002) and RDW (P < 0.001) showed statistically significant difference between hypothyroidism and euthyroidism, MCV (P = 0.005) showed statistically significant difference between hyperthyroid and euthyroid groups. CONCLUSIONS In case of patients with abnormal haematological parameters, thyroid hormones evaluation is necessary. KEYWORDS Hypothyroidism, Hyperthyroidism, Haemoglobin, Blood Count, Red Cell Indices

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